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알레르기접촉피부염 환자의 첩포검사에서(T.R.U.E. TEST^(R)) 판독일에 따른 결과 고찰
이한을 ( Han Eul Lee ),이종석 ( Jong Suk Lee ),이성열 ( Sung Yul Lee ) 대한피부과학회 2013 大韓皮膚科學會誌 Vol.51 No.2
Background: The patch test is widely used for diagnosis of allergic contact dermatitis. However, nearly half of positive reactions can be observed only on day 2 or day 4 and it is difficult to interpret these reactions. Objective: The purpose of this study is to assess the frequency of transient and delayed reactions in TRUE-test and detect common antigens that provoke these reactions. Methods: A total of 311 patients with allergic contact dermatitis were evaluated by TRUE-test between Jan 2007 and December 2011. Records of patch test results of day 2 and day 4 were reviewed and analyzed. Results: A total 311 cases of T.R.U.E. TEST^(R) records (male 79, female 232) were analyzed. Persistent reactions were observed in 80.1% patients tested, transient reactions were observed in 18.3%, and delayed reaction in 5%. Frequent allergens which showed transient reactions were cobalt dichloride (2.9%), nickel sulfate (2.2%), thiomersal (1.9%), and carba mix (1.6%), in order of frequency. Allergens which showed delayed reactions were nickel sulfate (0.3%), fragrance mix (0.3%), p-tert-butylphenol formaldehyde resin (0.43). Conclusion: Our results showed a relatively high frequency of transient reaction in T.R.U.E. TEST^(R). This suggests that additional reading at day 4 in the patch test would be of value. (Korean J Dermatol 2013;51(2):87∼93)
이한을 ( Han Eul Lee ),조홍기 ( Hong Ki Cho ),이성열 ( Sung Yul Lee ),이종석 ( Jong Suk Lee ),박영립 ( Young Lip Park ),황규왕 ( Kyu Uang Whang ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.12
Washboard nail is a dystrophy that presents as a series of ridges that extends across the nail. It is often accompanied by a central depression that extends from the cuticle to the free edge. Washboard nail is often a result of frequently repeated trauma, but sometimes predisposing factors cannot be found. When habitual tic is the cause of the lesions, restraining the habit is the most important treatment. Here, we report a case of a 6-year-old male with washboard nails on both thumbnails and was treated with topical 0.1% tacrolimus ointment. Significant improvement was observed after 4 months of application. This case suggests that topical tacrolimus can be considered as a primary therapy in the treatment of washboard nails in the absence of trauma. (Korean J Dermatol 2012;50(12):1054∼1056)
Voriconazole로 성공적으로 치료한 Scedosporium apiospermum에 의한 피부감염증
조홍기 ( Hong Ki Cho ),이한을 ( Han Eul Lee ),최영진 ( Young Jin Choi ),이상훈 ( Sang Hoon Lee ),황규왕 ( Kyu Uang Whang ),이종석 ( Jong Suk Lee ),이성열 ( Sung Yul Lee ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.2
Scedosporium apiospermum, an asexual state of Pseudallescheria boydii, is a widely distributed mould that can be found in the soil, manure, stagnant water and decaying vegetation. It has become an emerging pathogen among immunosuppressed patients but it can also cause infections in immunocompetent patients by penetrating trauma. This fungus is a classical cause of mycetoma and the localized skin infections caused by this mould are much rarer than mycetoma. We report a case of cutaneous S. apiospermum infection in a 79-year-old woman. She had erythematous plaque with crust and violaceous supprative nodules on the right forearm. The culture from pus showed typical white to gray colored cottony colonies of S. apiospermum. Treatment was started with voriconazole effectively. Skin lesions completely cured with no reccurence. Thus, voriconazole shows to be an effective treatment for Scedosporium infection. (Korean J Dermatol 2013;51(2):135∼139)