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      • KCI등재

        GaN-based Ultraviolet Passive Pixel Sensor for UV Imager

        이창주,함성호,박홍식 한국센서학회 2019 센서학회지 Vol.28 No.3

        An ultraviolet (UV) image sensor is an extremely important optoelectronic device used in scientific and medical applications because it can detect images that cannot be obtained using visible or infrared image sensors. Because photodetectors and transistors are based on different materials, conventional UV imaging devices, which have a hybrid-type structure, require additional complex processes such as a backside etching of a GaN epi-wafer and a wafer-to-wafer bonding for the fabrication of the image sensors. In this study, we developed a monolithic GaN UV passive pixel sensor (PPS) by integrating a GaN-based Schottky-barrier type transistor and a GaN UV photodetector on a wafer. Both individual devices show good electrical and photoresponse characteristics, and the fabricated UV PPS was successfully operated under UV irradiation conditions with a high on/off extinction ratio of as high as 103. This integration technique of a single pixel sensor will be a breakthrough for the development of GaN-based optoelectronic integrated circuits.

      • KCI등재

        A FIXED POINT APPROACH TO THE STABILITY OF APPROXIMATELY QUADRATIC-ADDITIVE MAPPINGS

        이창주,이양희 충청수학회 2012 충청수학회지 Vol.25 No.1

        In this paper,we investigate the stability of a functional equation $$ f(x + y+z) - f(x + y) - f(y+z)-f(x+z)+ f(x) + f( y) + f(z) =0$$ by using the fixed point theory in the sense of L. C\u adariu and V. Radu.

      • KCI등재

        Stability of a generalized polynomial functional equation of degree 2 in non-Archimedean normed spaces

        이창주,이양희 충청수학회 2013 충청수학회지 Vol.26 No.4

        In this paper, we investigate the stability for the functional equation f(3x + y) - 3f(2x + y) + 3f(x + y) - f(y) = 0in the sense of M. S. Moslehian and Th. M. Rassias.

      • KCI등재후보

        초기 혼합치열기에서의 Face mask의 임상적 적용

        이창주,김종수,권순원 大韓小兒齒科學會 2001 대한소아치과학회지 Vol.28 No.4

        Ⅲ급 부정교합은 전치가 수평적으로 반대로 물리는 양상 때문에 치과의사뿐만 아니라 일반인에 의해서도 쉽게 발견되므로 비교적 조기에 치과를 찾는 빈도가 높다. 이러한 Ⅲ급 부정교합 치료 시에 치과의사들이 사용할 수 있는 방법은 여러 가지가 있을 수 있으며 그 중 정형적 Face mask는 Ⅲ급 부정교합에 기여하는 모든 요소 즉, 상악골 후퇴, 하악전돌, 낮은 전방하안면고경에 전반적으로 영향을 미치기 때문에 가장 폭넓게 적용가능하고 가장 짧은 기간에 극적인 결과를 나타내기 때문에 대부분의 발육중인 Ⅲ급 증례에 적용될 수 있다. 이에 본원에 내원한 Ⅲ급 부정교합 환하에서 Face mask를 적용함으로써 다음과 같은 결과를 얻었다. 1. 전치부 반대 교합이 상악골의 전방이동, 하악골의 후하방 회전에 의해 해소되었다. 2. 경조직, 연조직에서 안모의 개선이 나타났다. Class Ⅲ malocclusion usually becomes manifested at a very early age, most typically evidenced clinically by the appearance of either an edge-to-edge incisor relationship or an anterior crossbite. Anterior crossbite, by itself, retards growth of maxilla, and accelerates growth of mandible. So, treatment should be started as early as the patient cooperates, removing any factors or forces that inhibit growth and development in the same physiologic maxillary displacement direction. The facial mask is effective in most developing Class Ⅲ patients, because the appliance system affects virtually all areas contributing to a Class Ⅲ malocclusion. Thus, the facial mask can be applied to most developing Class Ⅲ cases regardless of the specific etiology. In these cases, the results were followed. Anterior crossbite was corrected by anterior movement of maxilla and downward backward rotation of mandible and simultaneously, lower facial height was increased. So, it can be concluded that the facial mask is effective in treating growing patients with a deficient maxilla.

      • KCI등재

        Follicular Degeneration After Treatment of Follicle Stimulating Hormone in Prepubertal Mouse Ovary

        이창주,고경수,김지향,김진규,윤용달 한국발생생물학회 2000 발생과 생식 Vol.4 No.1

        FSH는 미성숙 설치류의 난포성장을 촉진하며, 강소형성 난포의 퇴화비율을 감소시킨다. 본 연구는 미성숙 생쥐에 난포성숙호르몬을 투여한 후 유발되는 난포의 조직학적인 변화를 규명하기 위해 시행되었다. 3주령의 ICR생쥐에 10 i.u.의 재조합 난포자극호르몬을 복강주사한 후 1일, 2일, 3일에 좌측 난소의 조직학적 변화를 관찰하였다. 강소형성전 난포의경우 FSH처리 후 시간에 따라 퇴화난포의 비율이 증가하였으나 강소형성 난포의 경우에는 유의한 변화를 보 Follicle stimulating hormone (FSH) stimulates follicle growth, and inhibits the follicle atresia in the immature rodent ovaries. The present study was carried out to know the histological changes of ovarian follicles after FSH treatment in the prepubertal mice. Ten i.u. of recombinant FSH was i.p. injected on 3 weeks old mice. After the treatment, at 1, 2 and 3 days, left ovaries were collected for the histological study. The atretic ratio of preantral follicles increased with time after FSH treatment. However, in the case of antral follicles, there was no significant change in the ratio. The degenerating follicles contained apoptotic granulosa cells, macrophage, and polymorphonuclear leukocytes in the follicular cavity. The present results suggest that follicular degeneration caused by FSH hyperstimulation could be mediated by apoptosis as well as the acute inflammation.

      • KCI등재

        Charaeteristics and Applications of the Established Testosterone Immunoassays

        이창주,이준영,윤용달 한국발생생물학회 2001 발생과 생식 Vol.5 No.1

        Testosterone의 radioimmunoassay (RIA) 가 1970년대 개발된 이래, 경제적이고, 측정 한계가 낮고, 감도가 높은 호르몬의 측정방법을 개발하여 왔다. 방사면역측정법 (RIA와 IRMA)은 비방사면역측정법 (NIA)로 대체되어 정밀도, 정확도, 특이도와 실용성 등이 크게 발전되었다. 최근 혈액, 타액, 분뇨 등에서 호르몬을 측정하여 남성과 여성의 성기능장애, 심리적스트레스나 기분의 변화, 폐경 및 남성호르몬 결핍증 등의 노화 현 Since the first radioimmunoassay (RIA) was developed in 1970s, many conventional RIAs and non-isotopic immunoassays (NIA) had been developed in which the degree of precision, accuracy, specificity and practicability have progressively increased. Recently ultrasensitive assay method at femtogram to determine testosterone in serum, saliva and feces is required for the study of sexual dysfunctions in male and female, monitoring the psychological stress and conditions, aging process such as menopause and partial androgen deficiency in aging male, the hormonal changes of small experimental animals etc. This review discussed the recentd evelopments of steroid assay methods, based upon the testosterone assay results of authors far 20 years, and the problems associated the assay set-up, the characterizations and applications of the established procedures, and desifls of assay, reliablity criteria, and the practical aspects of assay set-up and application, based upon the data of the authors. The present study demonstrates the general problems methods to be consider in order to set up the highly sensitive assay methods and to increase the assay quality and the necessity of assay quality control program. To improve the assay quality of each laboratory and to compare the assay results in homeland, the national QC programs should be organized.

      • KCI등재

        Stability of a general quadratic functional equation in non-Archimedean normed spaces

        이창주,이양희 충청수학회 2013 충청수학회지 Vol.26 No.2

        In this paper, we investigate the stability for the func-tional equation f(x+y+z)+f(x-y)+f(x-z)¡f(x-y-z)-f(x+y)-f(x+z) = 0 in non-Archimedean normed spaces.

      • KCI등재후보

        Developments of Hormone Assays, Second Generation: Non-Isotopic Immunoassays

        이창주,김상수,윤용달 한국발생생물학회 2005 발생과 생식 Vol.9 No.2

        면역측정법의 주요 발전 단계를 3가지로 구분한다. 즉 첫 발전 단계(제 1세대)는 방사성 호르몬(방사선 추적자, radiolabeled analyte marker)을 이용한 길항적 측정방법의 개발과 보급이다. 두 번째(제 2세대)는 단가 항체(monoclonal antibody, McAb)를 추적자로 만들고, 비방사성 표지자를 이용하여 비경쟁적 초감도의 측정방법이 면역진단 분야에 적용되는 단계이다. 세 번째(제 3세대)의 발전은 최소량화, 칩을 이용하는 The three important phases in the development of ligand immunoassays are identified and summarized. The competitive radiolabelled hormone measurement had been developed in the first and early in the second generations(1950s to 1960s), such as radioimmunoassays(RIA) or immunoradiometric(saturation) assays(IRMA), and used in all most of the hormone and also analyte in biological samples. In the second generation, ultrasensitive non-isotopic immunoassays(NIA) were developed using monoclonal antibodies(McAb), labelling the McAb and high specific activity non-isotopic labels. After their usefulness, advantages and disadvantages has been evaluated and non-competitive methods are discussed. The chip/microarray based multianalyte ligand assays(microspot or genechip methods) are developed and known as alternative ones in the third generation. We summarize the developments of NIAs and its usefulness, and then introduce briefly the new ligand assays.

      • KCI등재

        STABILITY OF A QUADRATIC-ADDITIVE TYPE FUNCTIONAL EQUATION IN NON-ARCHIMEDEAN NORMED SPACES

        이창주,이양희 호남수학회 2013 호남수학학술지 Vol.35 No.1

        In this paper, we investigate the stability for the functional equation 2f(x + y) + f(x - y) + f(y - x) - f(2x) - f(2y) = 0in non-Archimedean normed spaces.

      • 2000年代를 대비하는 산수과 敎育課程의 方向

        이창주 공주교육대학교 과학교육연구소 1992 과학교육연구 Vol.14 No.

        Our arithmetic curriculum has changed over 5-times since 1945, and term of change becomes gradually short and it is necessary to research the cur riculum in order to prepare the various society of 21 cen�tury, We have experienced a various arithmetic curriculum and with foundations, must study the develo�pemnt of curriculum in order to prepare for the community of information and international, furthermore, to meet the requirement of our traditional culture and social demand. In this paper, I study the variation of curriculum of our country and that of Japan’s with comparing and analyzing during the period from 1945 to the latest date, and research that mathmathic education current in several nations at the viewpoint of the objects, the contents and each nation’s teaching methods essentially can be sumarize as followings. (1) Our arithmetic curriculum and that of Japan’s has been repeated with on analogous current, only upkeeping some interval from the resemble culture of tradition and from the structure of cons�chiousness. (2) In two nations, the text books which are made by the uniformal curriculum are used, but our natin we use one kind, the authorized textbooks. In Japan, 6 kinds are used. (3) Statements of objects, contents domain classification, and units construction resembles. The autho�rized textbooks changed every 3 years. (4) Recently, mathemathic education current has distinction in each nations about intention establish�ment. But at large respects there has much resemblance in the educational and social case in U.S.A. (5) In contents composition, they teach basic knowledge, problem solving ability, approximation calcula�tion had mathematic as information, inference,. Also they treated elements in preparing the life-lea�rning to cope the various society. (6) Unified mathematics, applied mathematics, and mathematics for everybody are investigation, they try to develop creative curriculum.

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