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증례 식도 상부의 이소성 위점막에서 발생한 원발성 선암
이중민 ( Jung Min Lee ),박승우 ( Seung Woo Park ),배상운 ( Sang Woon Bae ),김재학 ( Jae Hak Kim ),감창우 ( Chang Woo Gham ),이세준 ( Se Joon Lee ),송시영 ( Si Young Song ),정재복 ( Jae Bock Chung ),강진경 ( Jin Kyung Kang ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.3
The incidence of esophageal adenocarcinoma is steadily increasing. Most of them, however, are attributable to adenocarcinoma arising from the lower esophagus, which is quite contrary to rare incidence of upper esophageal adenocarcinoma. The origins of esophageal adenocarcinoma are postulated to be Barrett`s esophagus, ectopic gastric mucosa, and esophageal gland. Barrett`s esophagus is widely accepted as being associated with lower esophageal adenocarcinoma. On the other hand, ectopic gastric mucosa, which is believed to remain due to congenital defect during the developmental stage and which is found as many as 10% of routine esophagogastroscopy, has been rarely proven to be the origin of upper esophageal adenocarcinoma. In Korea, to our knowledge, no case has been reported yet, and we herein report a case of upper esophageal adenocarcinoma originated from ectopic gastric mucosa with a brief review of previous reports. (Korean J Gastroenterol 2003;41:224-228)
이중민(Jung-Min Lee),임익태(Ik-Tae Im) 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.12
In this study, separation efficiency of a hydro cyclone is investigated using numerical simulation. Flow field of water including solid particles was solved using a two-fluid model. Separation efficiency of a hydrocyclone at various solid volume fraction and inlet velocity was found by numerical simulations. Results show that the efficiency decreased with increasing of inlet velocity and sand volume fraction.
이중민 ( Jung Min Lee ),김도영 ( Do Young Kim ) 대한간암학회 2009 대한간암학회지 Vol.9 No.-
In Korea, hepatocellular carcinoma (HCC) is a fourth leading malignancy with poor prognosis of 5 year survival reaching just 18.9%. The peak incidence is 6th decade and the incidence drops with decreasing age. However, young patients with HCC are not uncommonly encountered in clinical practice, and notably, even though managements with all available modalities are undertaken in these patients, the prognosis does not seem to be better. As such, many physicians feel that the behavior of HCC in young patients takes a more aggressive course than that in old patients. From this perspective, we performed a systemic review of previous literatures focusing on the question whether or not HCC in young patients is more aggressive; it was found that young patients with HCC had presentation of more advanced stage, more preserved liver function, but poor or equivocal survival rate. In the multivariate analysis, however, the poor outcome resulted not from young age, but from advanced stage, which was supported by similar or better outcome when the prognosis was compared with the same stage between young and old patients. Consequently, it could be inferred that an earlier detection of the tumor through earlier starting point of surveillance might improve the prognosis of young patients with HCC. However, a matter of cost-effectiveness should also be considered, which necessitates a further analysis on this issue.
이차성 비기능항진증에서 부분적 비장동맥색전술의 장기 치료 효과
이중민 ( Jung Min Lee ),전재윤 ( Chae Yoon Chon ),한재용 ( Jae Yong Han ),윤기태 ( Ki Tae Yoon ),문창모 ( Chang Mo Moon ),안상훈 ( Sang Hoon Ahn ),한광협 ( Kwang Hyub Han ),이종태 ( Jong Tae Lee ),문영명 ( Young Myoung Moon ) 대한내과학회 2007 대한내과학회지 Vol.72 No.5
목적: 간경변증 환자에서 이차성 비기능항진증이 동반되어 범혈구감소증이 생기면서, 그 중에서 특히 혈소판감소증이 임상적으로 문제가 되는 경우가 많다. 치료를 위해서는 과거에 비장적출술(splenectomy; SPL)을 시행하였는데 간기능 저하가 동반되어 있어서 수술 자체의 위험성이 많아 적응증이 안 되는 경우가 있다. 따라서 수술에 비하여 비침습적인 부분적 비장동맥색전술(partial splenic embolization; PSE)이 소개되고 있으며 결과가 양호한 것으로 알려져 있다. 간경변증으로 진단된 환자에서 PSE의 치료 효과에 대해서 고찰하고 SPL과의 치료 효과를 비교하였다. 방법: 1999년 1월부터 2003년 12월까지 간경변증 환자 중 PSE 또는 SPL을 시행한 환자를 대상으로 후향적 연구를 수행하였다. 이차성 비기능항진증에 의한 혈소판 감소증으로 출혈 증상이 있거나 혈소판감소증을 교정해야 할 목적으로 시행하였으며, 치료 전후의 혈액검사를 비교하였고 합병증의 유무를 확인하였다. 결과: PSE 군이 총 40명, SPL 군이 35명이었고, 남녀 비가 각각 27:13, 23:12로 남자가 더 많았으며, 평균 연령은 각각 50.8, 49.2세였다. 백혈구는 PSE 및 SPL 군에서 2년째에 4,450 및 5,560/μL로서 치료 전에 비해 유의한 증가를 보였고 혈소판도 양 군에서 2년째에 각각 144, 174 k/μL를 보여 유의한 증가를 보였으며 혈색소도 마찬가지로 2년째에 각각 13.7, 12.8 g/dL로서 치료 전에 비해서 유의한 증가를 보였다. Child-Pugh score를 계산하면 PSE 군은 치료 전 6.5에서 치료 후 5.5로 유의한 감소를 보였으며(p=0.04), SPL 군은 6.4에서 5.9로서 통계적인 차이가 없었다. 합병증은 양 군에서 경미하였고 사망, 출혈, 감염증의 심각한 합병증은 7.5% 이하에서 나타났으며 통계적 차이가 없었다. 결론: 이상의 결과로 PSE는 간기능이 비교적 양호한 환자에서 이차성 비기능항진증으로 의한 혈구감소증에 좋은 치료 방법으로 생각되며, 심각한 합병증의 발생은 적고 일부 간기능의 호전을 기대할 수 있어서 간경변증 환자에서 시행해 볼 수 있는 비교적 안전하고 효과적인 방법으로 생각된다. Background: Liver cirrhosis causes secondary hypersplenism and thrombocytopenia is clinically troublesome. Splenectomy (SPL) was thought to be the curative management for correcting thrombocytopenia. However, decompensated liver function prevents any surgical approach due to high morbidity and mortality. Hence, partial splenic embolization (PSE) has been introduced, which is a less invasive procedure. The purpose of this study was to assess the long-term therapeutic effects of PSE and to compare them with those of SPL. Methods: This study was performed retrospectively in patients who underwent PSE or SPL from Jan. 1999 to Dec. 2003. The patients either had symptoms of bleeding or they needed to correct their thrombocytopenia for further treatment of associated diseases. The therapeutic effects were evaluated, and the complications were assessed. Results: Forty and 35 patients were enrolled in the PSE and SPL groups, respectively. WBC, platelet and hemoglobin counts were all significantly increased at the 2 year follow-up in both groups. Child-Pugh score significantly decreased in the PSE group from 6.5 before treatment to 5.5 after treatment (p=0.004). Minor complications were easily controlled with supportive care, and major complications very rarely occurred in both groups. Conclusions: PSE and SPL both proved to be effective measures with few serious complications for treating pancytopenia in patients with liver cirrhosis. Considering the improved liver function (the prothrombin time) and the Child-Pugh score after PSE, it may be more reasonable to initially recommend PSE for the patients with liver cirrhosis and secondary hypersplenism. (Korean J Med 72:470-479, 2007)
이중민 ( Jung Min Lee ),박준용 ( Jun Yong Park ),김도영 ( Do Young Kim ),김경식 ( Kyung Sik Kim ),박영년 ( Young Nyun Park ),김명진 ( Myeong Jin Kim ),전재윤 ( Chae Yoon Chon ),한광협 ( Kwang Hyub Han ) 대한간암연구회 2009 대한간암학회지 Vol.9 No.-
Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis as HCC develops on base of cirrhosis in majority cases, which requires multidisciplinary approach. If feasible, however, surgical resection is the choice of treatment, and many previous studies and guidelines offered appropriate indications for surgical resection; firstly, preservation of liver function should be confirmed with traditional Child-Pugh classification or more recently with Indocyanine Green retention test or absence of portal hypertension. Secondly, several variables about the size, number, and vascular invasion of tumor should be taken into consideration. It is suggested that to lessen the risk of recurrence gross vascular invasion be absent and the number of tumor be single. Regarding the size of tumor, although risk of dissemination increases with size, some tumors may grow as a single mass and thus the size of tumor is not a clear-cut limiting factor. Based on above suggestions, we herein offer our experience of a patient with initial hopeful expectation of good outcome with surgical resection, but who eventually turned out to result in disseminated tumor recurrence. Further study, maybe regarding a combination of adjuvant or neoadjuvant transarterial chemoembolization/chemotherapy or radiotherapy, is necessary on how to manage such patient.
차우정 ( Woo-jeong Cha ),이중민 ( Jung-min Lee ) 한국미용예술경영학회 2011 미용예술경영연구 Vol.5 No.3
By recognizing the hair salon employees' satisfaction on working environment according to the working types, this study purposed to suggest some improvements for them to work better workplace environment. For this purpose, the survey was conducted targeting some employees in hair salons located in Seoul and kyonggi province, and the 589 questionnaire copies were analyzed using the SPSS 16.0 statistical program. The analysis results are as follows. First, the demographic intypeation about the respondents showed that most respondents were single women in their 20s, and their income range was from 1 million to 2million won. Second, the working types of respondents showed that most respondents were staff working in franchised hair ships for about 10~12 hours every day with 4 duty-off days per month. Third, the respondents' satisfaction level on the working environment was somewhat lower than the moderate level. Fourth, their satisfaction on working environment according to demographic features showd there were some differences among groups in terms of age, marriage, monthly income, smoke amount, drinking frequency. Fifth, the respondents' satisfaction on the working environment showed there were some differences among groups in terms of hair salon type, the staff number, the salon location, their working period in current workplace, the hairdresser carrier, the position, the working type, the working hours, the average number of monthly holidays, and the wage type. As the research result, this study suggests following improvements for the better working environment. First, each hair salon needs some ways to shorten the working hours and to increase the number of duty-off days. Second, each hair salon should set some chances to promote the friendship among staff. Third, each hair salon should take more efforts to set the reservation culture in order to secure staffs suitable work amount and rest. Fourth, each hair salon should induce to create high additional values through more efficient customer management. Fifth, each hair salon needs to actively utilize the online media. Based on these improvements, this study hopes that the employees of hair salons work in better working environment, produce more satisfactory performance, and that the beauty industry will be more advanced.