일부 한국 성인 남성 흡연자들의 림프구 DNA 손상의 증가

이주현,오은하,이준영,설동근,김주자,이은일,Lee, Joo-Hyun,Oh, Eun-Ha,Lee, June-Young,Sul, Dong-Geun,Kim, Joo-Ja,Lee, Eun-Il 대한예방의학회 2007 예방의학회지 Vol.40 No.1

Objective : The purpose of this study was to evaluate the levels of DNA damage in human lymphocytes caused by smoking and other lifestyle factors. Methods : The study population consisted of 173 normal healthy male adults from 21 to 59 years old. The demographic and lifestyle variables were obtained from administered questionnaires. The level of lymphocytic DNA damage in the peripheral blood was evaluated by the Comet assay. Statistical analyses were done by general linear model analysis and Dunnett's multiple comparison. Results : The difference in DNA damage between smokers and non-smokers was statistically significant. The means for the Tail%DNA were found to be 10.48 in the current smokers and 9.60 in the non-smokers (p < 0.05). The tail moment means were 1.58 and 1.45 (p < 0.05) for the current smokers and non-smokers, respectively. The number of cigarettes smoked per day did not result in a significant difference in the level of DNA damage among the smokers. Other lifestyle factors such as age, and drinking and exercise habits were not related to DNA damage. Conclusions : The DNA damage in the lymphocytes of smokers was found to be significantly higher than that for non-smokers. However, the number of cigarettes smoked per day was not related to DNA damage. Further study is needed to evaluate the relationship between the amount of smoking and level of damage to DNA. In addition, the status of DNA repair activities should be assessed.

영재 학생들을 위한 과학사-CPS 수업 모형을 활용한 분자생물 영역 수업 프로그램의 개발 및 적용

이주현 ( Ju Hyun Lee ),이미숙 ( Mi Sook Lee ),주희영 ( Hee Young Ju ),이길재 ( Kil Jae Lee3 ) 경북대학교 과학교육연구소 2011 科學敎育硏究誌 Vol.35 No.2

This research was aimed to develop and apply the molecular genetics teaching program based on the history of science and creative problem solving model (HS-CPS model) for gifted students. Based on the strategies of creative problem solving and scientific theory development, the HS-CPS teaching program were developed. This program was applied to 8 first and second graders of the special class for invention activity in a high school. Creative problem solving ability in science and the understanding of DNA and gene concept were tested in pre and post of 12 lessons. The results were as follows: First, creative problem solving ability in science was improved meaningfully. Second, HS-CPS teaching program was effective in the understanding of DNA and gene concepts. Third, the students responded positively to the program evaluation questionnaire.

초미세 결정립 조직을 만들기 위한 복합전단가공법에 관한 연구

이주현,이진호,Lee, Ju-Hyun,Lee, Jin-Ho 한국군사과학기술학회 2008 한국군사과학기술학회지 Vol.11 No.4

The development of the equal channel angular pressing(ECAP) process in metals has recently provided a feasible solution to produce ultra-fine or nano-grained bulk materials with tailored material properties. However, ECAP process is difficult to scale up commercially due to requirements of an excessive load. In this paper, a new Hybrid-ECAP process with torsional die is considered to obtain materials of ultra-fine grain structure under low forming load. An upper bound analysis and numerical simulation (DEFORM 3D, a commercial FEM code) are carried out on the torsional die. By the upper bound analysis, analytical expression for the compression force and rotation speed are obtained. By the FEM analysis, the distribution of strain, stress and deformation are obtained. These results show that the Hybrid-ECAP is a useful process because this process can obtain the homogeneous deformations with relatively low forming load. Additionally, due to decreased forming load, die life can be improve.

소아환자에서 chloral hydrate와 hydroxyzine을 사용한 진정치료 시 생징후 평가

이주현,박호원,Lee, Ju-Hyun,Park, Ho-Won 대한소아치과학회 2002 大韓小兒齒科學會誌 Vol.29 No.3

최근 치과에 내원하는 환아의 연령이 어려지고, 장애아 및 행동조절이 어려운 환아의 치료에 관심이 높아지고 있어 이를 위한 한가지 방법으로 진정치료가 고려되고 있으며 그 중 chloral hydrate/hydroxyzine을 사용한 진정치료가 널리 오랫동안 사용되어 왔다. 이 연구에서는 강릉대학교 치과병원 소아치과에 내원하여 국소마취 하 수복치료가 필요하고, 통상의 행동조절에 반응하지 않거나 너무 어려 행동조절이 불가능한 아동을 대상으로 chloral hydrate/hydroxyzine을 사용 진정치료를 시행하고 생징후를 측정하였다. 이상의 결과 생징후는 chloral hydrate/hydroxyzine을 사용한 진정치료시 일시적 자극을 제외하고는 큰 변화를 보이지 않으며, 환아의 수면에 따른 호흡과 심박수의 감소가 관찰되었다. 따라서, 이러한 진정치료는 행동조절이 불가능하거나 아주 어린 아동에서 생징후에 영향을 적게 주면서 적절한 진정을 유도할 수 있는 방법이라 여겨진다. Currently, the ages of the patients visiting dental hospital for dental care are becoming younger and the interest in the treatment for the handicapped and incapable of cooperation children increases. As a method for treatment of these patients, the sedation treatment is considered. A dental sedation using chloral hydrate and hydroxyzine of them were used widely and for a long time. In this study, the samples were consisted of incapable of cooperation or very young children required treatment of restoration under local anesthesia. Then, the vital signs were accessed in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. As a result of this study, the vital signs were little different in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. Simply, the respiration rate and pulse rate decreased according to sleeping of patients. Therefore, the sedation using the combination of chloral hydrate and hydroxyzine induced to appropriate sedation in incapable of cooperation or very young children with little effects of vital signs.

컴퓨터 소프트웨어를 이용한 인지 훈련 방법의 연구 동향

이주현,오도영,구교인,Lee, Juhyeon,Oh, Doyeong,Koo, Kyo-In 대한의용생체공학회 2014 의공학회지 Vol.35 No.6

Mild cognitive impairment is status between healthy people and dementia patients. In order to prevent dementia or slow its progression, cognitive interventions could be effective. In this paper, review of the cognitive intervention with computer software was undertaken. Previous reports showed that the cognitive intervention with additional equipment could practical to the mild cognitive impairment.

전력계통 안정도 확보를 위한 발전기 무효전력 성능시험

이주현,Lee, Ju-Heon 한국열병합발전협회 2006 열병합발전 Vol.53 No.-

원전 디젤발전기 디지털 다중화 여자시스템 개발 및 적용

이주현,Lee, Ju-Hyeon 한국열병합발전협회 2010 열병합발전 Vol.78 No.-

FTIR을 이용한 복합레진의 중합도 비교

이주현,박호원,Lee, Ju-Hyun,Park, Ho-Won 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.2

The degree of conversion of cross-linked polymer has great importance in determining the physical and mechanical properties, and biocompatibility. Therefore, this study examined the comparison of light-cured composite resin polymerization of various light-curing systems composed of plasma arc, halogen, LED curing units and pluse-delay curing with FTIR. From this experiment, The following results were obtained : 1. From FTIR, the degree of conversion(DC) of composite resin was 34.52-49.31%, DC of composite resin used in Flipo was $39.36{\pm}1.22%$, CrediII $45.64{\pm}1.34%$, XL3000 $43.48{\pm}1.34%$, VIP(mode 4) $44.31{\pm}0.72%$, LUXOMAX $49.31{\pm}2.37%$, Elipar Freelight $44.51{\pm}0.62%$ and $34.52{\pm}0.85%$ in pulse-delay curing. 2. The degree of conversion of composite resin in each light-curing unit was highest DC of the LUXOMAX system, lowest DC of the pulse-delay curing. 3. Compared with other curing system, Flipo, LUXOMAX, and pulse-delay curing were significant difference(p<0.05). 4. In same curing method group, the differences of each light-curing unit were no significace in halogen(conventional) curing method(p>0.05), but significance in plasma arc curing and LED curing method(p<0.05). 치과용 복합레진의 중합률은 레진 기질내의 이중결합의 전환도를 나타내는 것으로 이는 재료의 물리적 성질과 기계적 성질 및 생체 친화성에 영향을 미친다. 레진의 중합도가 증가하면 취성과 수축이 증가하고 중합도가 낮으면 기계적 물리적 성질이 감소한다. 따라서 본 연구에서는 광중합형 복합레진을 사용하여 플라즈마 아크 중합기 2종, 할로겐 중합기 2종, LED 중합기 2종, pulse-delay curing의 서로 다른 중합방법의 경우를 FTIR 분석법으로 복합레진의 물리적 기계적 성질 및 생체친화성에 영향을 미치는 중합률을 분석하여 다음과 같은 결과를 얻었다. 1. 광중합 복합레진의 중합률은 FTIR로 측정하였을 때 34.52-49.31%사이로 나타났으며 플라즈마 아크 중합의 경우 Flipo는 $39.96{\pm}1.22%$, CrediII는 $45.64{\pm}1.34%$로, 할로겐 중합시 XL3000은 $43.48{\pm}1.34%$, VIP의 mode 4 사용시는 $44.31{\pm}0.72%$, LED의 LUXOMAX는 $49.31{\pm}2.37%$, Elipar Freelight는 $44.51{\pm}0.62%$, pulse-delay curing시에는 $34.52{\pm}0.85%$로 나타났다. 2. 각 중합 방법별로 중합률은 LED 중합 방법을 이용한 LUXOMAX가 다른 실험군에 비하여 가장 높은 중합률을 나타냈으며 pulse-delay curing 방법이 가장 낮은 중합률을 보였다. 3. Flipo 중합기, LUXOMAX 중합기, pulse-delay curing 방법이 다른 중합기와 비교하여 통계적으로 유의한 차이를 보였다(p<0.05). 4. 각 중합방법이 동일한 군 내의 중합기기별 차이에서는 할로겐에서는 광중합기 사이에 중합률의 차이를 보이지 않았으나 플라즈마 아크에서는 CrediII가, LED에서는 LUXOMAX가 중합률이 높았다(p<0.05).

긴급 메시지의 우선 처리를 위한 무선센서네트워크 MAC 프로토콜 설계

이주현,박형근,Lee, Ju-Hyeon,Park, Hyung-Kun 한국정보통신학회 2010 한국정보통신학회논문지 Vol.14 No.4

Wireless Sensor Networks are widely applied for organizing real-time monitoring systems. Unlike general kinds of sensor networks, it is important to preferential send emergency data to the control server when urgent events are occurred. But IEEE 802.15.4 MAC protocol which is generally deployed for wireless sensor network does not support algorithm for urgency data handling. Therefore, we proposed a MAC protocol which consider the priority for the urgency data handling. 반도체 검사장비 환경과 같이 실시한 환경 모니터링을 위한 무선 센서 네트워크가 많은 분야에서 응용되고 있다. 그러나 일반적인 센서네트워크와는 달리 모니터링 시스템의 경우 긴급한 처리가 필요한 데이터가 발생하게 되는데, 이때 긴급 데이터는 다른 일반적인 모니터링 데이터에 비해 우선적으로 관리서버에 전송되어져야 한다. 반면 일반적으로 센서 네트워크에서 사용되는 IEEE 802.15.4 MAC 프로토콜에서는 이러한 긴급 데이터 처리를 위한 알고리즘을 제공하지 않는다. 따라서 본 논문에서는 데이터의 우선순위 및 긴급 데이터전송을 위한 MAC 프로토콜을 제안하였다.

Design Methodology-T-DMB(지상파 DMB) Synchronizer 설계 기술

이주현,엄낙웅,Lee, Ju-Hyeon,Eom, Nak-Ung IT-SOC협회 2005 IT SOC magazine Vol.8 No.-