객체지향 및 동적연동 교육용 통계패키지 K-plot 개발

이정진,이태림,강근석,김성수,박헌진,이윤동,심송용,Lee, Jung Jin,Lee, Tae Rim,Kang, Gunseog,Kim, Sungsoo,Park, Heon Jin,Lee, Yoon-Dong,Sim, Songyong 한국통계학회 2013 응용통계연구 Vol.26 No.3

현대통계학은 많은 분야에서 사용되고 있으나 사용자들이 통계학적 개념을 이해하는데 어려움을 겪고 있다. 한편으로는 초등학생 때부터 줄기잎 그림이나, 비율자료의 원그림 등은 물론이고 평균과 같은 기술통계를 배우고 있다. 초등학교 고학년이나 중학교 저학년 학생들을 위한 직관적인 통계 패키지가 있다면 미래의 통계 사용자들인 이들 학생들이 통계적 개념을 이해하는데 많은 도움이 될 것이라고 생각하여 직관에 기초한 통계 패키지를 개발하였다. Modern statistics is used in many fields; however many users face difficulties in understanding statistical concepts. On the other hand, elementary school curriculum covers stem and leaf plot, pie chart, charts for proportional data as well as descriptive statistics including the mean. We find that an "intuitive" statistical package focused on 5-8 graders for statistical education will help future statistics users understand statistical concepts at earlier stages of their lives.

삼출성 나이관련황반변성 반대안의 새로운 신생혈관 발생 빈도

이정진,유영주,조성원,김종우,Jung Jin Lee,MD,Young Ju Lew,MD,Sung Won Cho,MD,Jong Woo Kim,MD 대한안과학회 2013 대한안과학회지 Vol.54 No.10

Purpose: To investigate the development of new choroidal neovascularization in fellow eyes of patients treated for unilateral exudative age-related macular degeneration (AMD). Methods: Three hundred fourteen patients who were first diagnosed with unilateral exudative AMD and treated with intravitreal bevacizumab or ranibizumab were studied retrospectively. Results: New exudative AMD developed in 7.0% of fellow eyes after 1 year, 10.8% after 2 years and 13.7% after more than 2 years. According to the subtype of exudative AMD, there were no significant differences between classic CNV, occult or minimally classic CNV, and PCV in the incidence of new exudative AMD. After 2 years, a higher conversion rate was found in the bevacizumab-treated group than the ranibizumab-treated group. Conclusions: The cumulative incidence of involvement in fellow eyes with exudative AMD was 13.7% over 2 years.

끝단 질량이 부착된 복합재료 날개의 진동특성

이정진,이인 ( Jung Jin Lee,In Lee ) 한국복합재료학회 1990 Composites research Vol.3 No.2

스마트 무인기 개발 프로그램의 시스템 엔지니어링 적용

이정진,김재무,임철호,Lee, Jung Jin,Kim, Jai Moo,Lim, Cheol Ho 한국시스템엔지니어링학회 2005 시스템엔지니어링학술지 Vol.1 No.2

The Smart UAV Program was motivated by a huge potential market, a various application and future core technologies. The Smart UAV system is defined as the advanced air vehicle with the smart technology such as collision awareness and avoidance, healthy monitering and self-recovering, intelligent active control. Due to the broad interest by government, industry and academia, Smart UAV development center and government steering committee were established. The organization of the Smart UAV program consists of domestic/international companies and academia. In this paper, the process and application of system engineering was introduced for Smart UAV development program.

스마트 무인기 시스템 요건 도출

이정진,Lee, Jung Jin 한국시스템엔지니어링학회 2005 시스템엔지니어링학술지 Vol.1 No.1

This paper presents the brief generation process of system requirements for Smart UAV from a development objective. The current Smat UAV requirements deal with the restricted life cycle from development to test and verification exclusive of full life cycle because of the new technology demonstration research program funded by governments. The Smart UAV system consists of flight vehicle, avionics, communication link, payload, ground control station and ground supporting system. In this paper, top-down flown requirements are introduced how to allocate to each sub-system.

총의치 제작에 적용 가능한 디지털 기술과 임상적 고찰

이정진,송광엽,박주미,Lee, Jung-Jin,Song, Kwang-Yeob,Park, Ju-Mi 대한치과의사협회 2019 대한치과의사협회지 Vol.57 No.9

Digital technology has changed various aspects of the clinical dentistry. The intraoral scanner and Computer-aided design / Computer-aided manufacturing (CAD-CAM) technology are widely used in fabricating fixed prostheses and in implant surgery. These technologies greatly improved the efficiency of clinical and laboratory procedures. With all newly introduced software, devices, and clinical studies, digital technology has been actively applied in removable prostheses. It is now possible to fabricate the removable prostheses more quickly and easily through subtractive and additive manufacturing. Various clinical and laboratory protocols were introduced by many manufacturers. The purpose of this review is to summarize the literature on digital technology for fabricating complete denture with current status and future perspectives.

Helicobacter pylori에 의해 호중구 및 위점막 세포로부터 유도되는 Leukotriene $B_4$의 생성에 미치는 Rebamipide의 영향

이정진,한복기,노재열,이광호,윤희상,김말남,정명희,Lee, Jung-Jin,Han, Bok-Gee,Ro, Jai-Youl,Rhee, Kwang-Ho,Youn, Hee-Shang,Kim, Mal-Nam,Chung, Myung-Hee 대한약리학회 1997 The Korean Journal of Physiology & Pharmacology Vol.1 No.6

Leukotrienes(LTs) are hewn to act as a mediator provoking tissue response in inflammation. This finding implicates that LTs also play important roles in the pathogenesis of H, pylori-induced gastritis and gastric ulceration. Rebamipide is being currently used as a therapeutics for gastritis and peptic ulcer, but their mechanisms of action have not been known clearly yet. One possibility is that their therapeutic effects are ascribed to interfering with the H. pylori-induced release of LTs from neutrophils and gastric mucosal cells. In the present study, this possibility was tested using $LTB_4$ as the test material in human neutrophils and Kato III cells(gastric adenoma cells as a substitute for gastric mucosal cells). The release of $LTB_4$ from both neutrophils and Kato III cells was time and H. pylori-dose dependent. The maximum release of $LTB_4$ was induced by neutrophils and Kato III cells when these cells incubated with H. pylori $(4.8{\times}10^8\;cells/ml$ for 30min. But in the presence of rebamipide the release of $LTB_4$ from these cells was suppressed in dose dependent manners. The release was completely suppressed at 1.0 mM of rebamipide in neutrophils and 2.0 mM of this drug in Kato III cells, respectively. We also obtained the results that the release of $LTB_4$ was induced by A23187$(Ca^{2+}\;ionophore)$ and the A23187-induced release was also inhibited by rebamipide. It seems that the machanism of action of rebamipide is through its interaction with the level of intracellular $Ca^{2+}$. In view of the roles of $LTB_4$ in inflammatory reaction and the roles of H. pylori in gastritis and peptic ulcer, the effects of this drug observed in this study may contribute to their therapeutic action in these gastric disorders.

악성두피종양환자에게 사용되는 보루스헬멧(Bolus-helmet)의 제작방법 및 유용성에 관한 연구

이정진,문재희,김희성,김군주,서정민,최재훈,김성기,장인기,Lee, joung jin,Moon, jae hee,Kim, hee sung,Kim, koon joo,Seo, jung min,Choi, jae hoon,Kim, sung gi,Jang, in gi 대한방사선치료학회 2021 대한방사선치료학회지 Vol.33 No.-

본 연구는 악성두피종양 환자를 대상으로 자체 개발한 보루스헬멧(bolus-helmet)의 제작방법에 관한 소개 및 유용성 평가에 관한 연구이다. 두피종양환자의 치료를 위한 헬멧제작(helmet-production)에 있어 매우 창의적이고 다양한 방법의 연구들이 시도되어 왔고, 앞으로도 지속되어져 나갈 것이지만, 보고된 대부부분에 연구자료에서 헬멧(helmet)의 제작에 소요되는 시간적 경제적인 비용이나 제작의 편의성과 과정의 복잡성으로 인해 환자가 부담해야 하는 심리적인 부담감과 신체적 물리적 불편함은 크게 감소되지 않았으며, 치료효과를 높이기 위한 방안으로 최근 연구되고 있는 3D-프린터(printer) 기술과 같이 보다 첨단화된 기술과 장비를 사용하는 등에 연구들이 소개되고 있는데 이러한 방안들 또한 시간적 경제적인 소요비용과 심리적 물리적 부담을 오롯이 환자의 몫으로 보다 가중되고 있는 것은 아닌가? 하는 우려의 생각 또한 지울 수 없는 것이 현실이다. 이에 본원에서는 보루스(bolus)가 가진 물리적 성질을 그대로 유지하고 사용함으로 별도의 추가비용의 발생이 없이, 보루스(bolus)를 이용해 헬멧(helmet)을 제작함으로 환자에게 발생된 물리적 신체적인 불편함을 감소시키고자 하였으며, 헬멧의 제작에 요구되는 절차와 시간을 줄이고자 안내서(guide-line)를 제작하여 공유함으로 약 3~40분의 시간이면 누구나 쉽게 제작이 가능한 시스템을 마련하도록 했다. 헬멧(helmet)의 제작에 소요되는 시간과 환자가 부담해야 하는 경제적 비용 및 물리적인 불편함을 감소시킴으로 보이지 않게 발생되는 환자의 심리적 부담 또한 최소화할 수 있었다고 사료되며, 추가적으로 헬멧의 유용성 평가에 있어서도 공기층(air-gap)의 발생간격을 줄이는 방안을 지속적으로 모색하고 발전시켜 나감으로 결과적으로 2.0mm이내로 유지하는 방안을 본 연구를 통해 제작방법과 함께 소개할 수 있게 되어 매우 반갑게 생각된다. 본원에서 제공한 헬멧의 제작에 관한 안내서(guide-line)을 통해 방사선종양학과에 종사하는 누구나 보루스(bolus)를 이용하여 방사선 치료에 요구되는 헬멧(helmet)을 쉽게 제작할 수 있게 되기를 바라며, 제작과정에서 생기는 궁금한 사항이나 문의가 있다면 언제든지 본 연구자의 메일과 휴대폰을 통해 문의해 주시기를 적극적으로 바라고 소망합니다. This study is about the introduction and usefulness evaluation of the manufacturing method of the bolus-helmet. Helmet-production for the treatment of scalp tumor patients has been tried and will continue in many creative and various ways. However, Most of the research data did not significantly reduce the psychological burden and physical and physical discomfort that the patient had to bear due to the time and economic cost required for the production of the helmet, the convenience of production, and the complexity of the process. In addition, recently, studies using more advanced technologies and equipment such as 3D-printer technology, which are being studied as a way to increase the treatment effect, are being introduced, but the time, economic cost, and psychological and physical burden are still the sole responsibility of the patient. Isn't it getting worse? The reality is that the thoughts of concern cannot be erased. Therefore, by maintaining the physical properties of the bolus and manufacturing a helmet without incurring additional costs, the physical and physical discomfort aggravated to the patient was reduced and the procedure and time for helmet manufacturing were minimized. In this way, it was possible to reduce the time, economic cost, and physical discomfort required for the production of the helmet, and it was also possible to minimize the psychological burden of the patient, although it is invisible. Additionally, in evaluating the usefulness of helmets, we are able to continuously seek and develop ways to reduce the air-gap interval, and as a result, we will be able to introduce a method to keep it within 2.0mm along with the manufacturing method through this study. I feel very welcome. Finally, I hope that anyone working in the Department of Radiation Oncology will be able to easily manufacture the helmet required for radiation therapy using a bolus through the guide-line on helmet manufacturing provided by this institute. I hope and hope that if you have any questions or inquiries that arise during the production process, please feel free to contact us through the researcher's e-mail or mobile phone at any time.

원양어선 조업 데이터의 혼합 극단분포를 이용한 이상점 탐색 연구

이정진,김재경,Lee, Jung Jin,Kim, Jae Kyoung 한국통계학회 2015 응용통계연구 Vol.28 No.5

남극해에서는 우리나라를 포함한 연안 강대국들의 원양어업이 활발히 성행하고 있다. 주인 없는 남극해의 생태계를 보호하기 위해 조업 국가들은 남극해양생물자원보존위원회를 만들고 협약을 맺어 일정한 어획량만 조업하고 금지기간과 금지구역을 설정하여 불법조업을 방지하고 있다. 남극해에서 조업하는 어종 중의 하나가 이빨고기(tooth fish)인데 비싼 값 때문에 불법조업이 있는 경우가 많다. 한 배의 조업성과는 CPUE(catch per unit effort)로 나타낼 수 있고, 한 지역에서 조업한 배들의 CPUE는 단일 또는 혼합 극단분포 형태를 가진다. 단일 극단분포일 경우 이상점 탐색은 상위 백분위수를 이용하면 된다. 본 논문은 자료가 혼합 극단분포인 경우 이상점 탐색을 위한 통계적 방법을 연구하고자 한다. 본 연구에서는 자료에 적합한 혼합 극단분포 모형을 EM 알고리즘으로 추정한 후 로그 가능도함수 값을 이용하거나 사후 확률을 이용한 이상점 탐색 알고리즘을 제안한다. 이 방법을 남극해 조업 데이터에 적용하여 시뮬레이션 한 결과 통계적 방법 적용의 가능성을 보여주었다. Deep-sea fishery in the Antarctic Ocean has been actively progressed by the developed countries including Korea. In order to prevent the environmental destruction of the Antarctic Ocean, related countries have established the Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) and have monitored any illegal unreported or unregulated fishing. Fishing of tooth fish, an expensive fish, in the Antarctic Ocean has increased recently and high catches per unit effort (CPUE) of fishing boats, which is suspicious for an illegal activity, have been frequently reported. The data of CPUEs in a fishing area of the Antarctic Ocean often show an extreme Distribution or a mixture of two extreme distributions. This paper proposes an algorithm to detect an outlier of CPUEs by using the mixture of two extreme distributions. The parameters of the mixture distribution are estimated by the EM algorithm. Log likelihood value and posterior probabilities are used to detect an outlier. Experiments show that the proposed algorithm to detect outlier of the data can be adopted instead of simple criteria such as a CPUE is greater than 1.

지구온난화에 따른 국내 기후변화와 젖소 착유우의 생산효율에 미치는 영향 평가 : 모델 시뮬레이션을 이용한 접근

이정진,이준성,김종남,서자겸,조남철,박성민,기광석,서성원,Lee, Jung-Jin,Lee, Jun-Sung,Kim, Jong-Nam,Seo, Ja-Keum,Jo, Nam-Chul,Park, Seong-Min,Ki, Kwang-Seok,Seo, Seong-Won 한국유기농업학회 2013 韓國有機農業學會誌 Vol.21 No.4

지난 25년간 지구온난화로 인한 국내 기후변화 양상은 지역 간에 차이가 있어, 고온지역은 평균온도의 증가를 보이지는 않았으나, 최저기온의 지속적인 상승과 그에 따른 열대야 발생을 확인할 수 있었다. 또한 그로 인한 젖소의 고온스트레스 발생, 섭취량의 감소 및 생산성 저하가 예상된다. 저온지역의 경우에는 여름철 평균온도 및 최저온도의 상승으로 인해 연평균기온이 유의적으로 상승한 반면, 겨울철에는 오히려 최저기온의 지속적인 하강이 관찰됨에 따라 동물의 저온스트레스가 가중될 것으로 예상된다. 착유우가 저온스트레스 상태에 있을 때는 에너지요구량과 건물섭취량이 증가하여 생산 효율이 떨어지며, 사료효율의 감소로 경제성은 감소되고 우유 생산비는 증가한다. 특히, 극심한 저온스트레스 또는 사료, 음수 및 우사바닥의 결빙은 섭취량 감소를 야기하며 이에 따른 생산성의 저하는 더욱 가중될 것으로 예상된다. 결론적으로 지구온난화로 인한 기후변화에 따른 지역별 영향은 다르며, 온도 스트레스에 의한 낙농우의 생산성 저하를 최소화하고, 동물의 복지와 건강을 증진시키기 위해서는 지역별 기후변화 특성에 맞춘 사양기술의 개발이 필요하다. The objectives of this study were to access climate change by global warming in Korea, and to investigate its effects on production efficiency of lactating dairy cows. Two regions, Daegu and Daekwanryung, were selected to represent a warm and a cold area, respectively. Time-series analyses on meteorological records for 25 years (from January 1, 1988 to December 31, 2012) revealed significant and different climate changes in two regions. In the warm area there has been a significant (P<0.05) increase in low temperature during the summer, which can cause heat stress to the animal. On the other hand, a decrease in low temperature during the winter was observed in the cold region (P<0.01), and cold stress in winter can thus be an issue in this region. Simulations using a model integrated the Korean feeding standard for dairy cattle and the environmental effect module of Cornell Net Carbohydrate and Protein System, indicated that a reduction in feed efficiency can be a problem during the winter in the cold region while during the summer in the warm area. We conclude that the effect of climate change by global warming varies in different areas in Korea and a region-specific management strategy should be developed in order to maintain productivity, health and welfare of lactating dairy cows.