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      • KCI등재

        삼나무 , 편백나무산출묘(山出苗)의 활착영향인자(Ⅰ)

        이정석,오광인 한국임학회 1979 한국산림과학회지 Vol.43 No.1

        삼나무, 편백나무의 經濟林 造林에 있어서 활착율이 極히 低調한 事例가 往往 있었다. 이에 對한 영향 因子를 究明코저 一次로 1-1의 實生山出苗와 삼나무의 揷木苗를 供試材料로 하여 室外, 室內 OED green을 葉莖에 處理한 것과 無處理한 것을 午前, 午後 종일 室內에서는 4日間 乾燥處理한 後 침적처리 시험을 하였으며 아울러 함수율을 測定分析하였다. 處理된 苗木은 同一 條件의 苗床에 植栽하여 만족할만한 관리를 하였던 바 다음과 같은 結果를 얻었다. 1. 삼나무, 편백나무의 山出苗의 OED green처리는 室內와 室外間에 高度의 有意性이 있었으며 무처리의 경우 오전, 오후, 종일 間에도 高度의 유의성이 있었다. 침적처리는 유의성이 없었다. 2. 삼나무 揷木苗는 건조처리간에 고도의 유의성이 있었다. 건조시간과 침적시간과의 상호작용에 유의성이 있었다. (6時間 건조할 경우 8時間 침적하였을 때 效果가 있었다) 3. 室內에서 4日間 건조처리를 계속했을 때 2日 경과 後부터 활착율이 현저히 떨어졌다. OED green 및 침적처리는 유의성이 없었으나 무처리에 비해 좋았다. 4. 함수율은 9時부터 15時사이에 급속히 떨어졌으며 室內에 比하여 室外處理가 극히 낮았다. 5. OED green과 無處理間의 含水率은 差가 적었다.

      • 국립중앙박물관 설계경기 참여안의 공간구조 비교분석

        이정석,김영욱,박영기 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

        This study intends to find out each plan's distinctive quality of spatial structure through a Comparative Study on the spatial structure of Entries in the International Architectural Competition for the National Museum of Korea. We use some programs based on Space Syntax theory for a Comparative Study on the spatial structure of Entries. The results of this study show how it paid special attention to study and evaluation in the process of architectural plan and judgment.

      • KCI등재

        DMF함유 혼합 유기용제에 대한 인화점의 측정과 평가

        이정석,한우섭,이근원 한국화재소방학회 2019 한국화재소방학회논문지 Vol.33 No.4

        The flash points of DMF based organic solvent mixtures used in the synthetic leather manufacturing process weremeasured. The test group was composed of seven types of solvent mixtures, which included DMF, toluene, and MEK. Eachflash point was tested according to the international standard test methods of KS M 2010. The flash points were thenpredicted using some prediction models and compared with the measured data. From the analysis results, the binarymixtures with a mole ratio of less than approximately 0.7 showed that the measured values were under 25 ℃. This showedthat the expectation for the flammable risk lowering effects due to the mixing of high flash point materials was reduced. In addition, the predicted values were evaluated using the average absolute deviation (A.A.D). The results showed that theLe Chatelier’s models had an “A.A.D” of 1.95 ℃ and were the closest to the measured values. 본 연구에서는 합성피혁 제조 공정에서 주로 사용되는 혼합 유기용제 중에서 디메틸포름아마이드(Dimethylformamide,DMF)를 기준물질로 톨루엔과 메틸에틸케톤 등이 혼합된 2성분 및 3성분 혼합물질 7종류에 대하여 국제적으로 표준화된 시험방법을 이용하여 인화점을 측정하였다. 그리고 몇 가지 예측모델을 이용하여 인화점을 예측하고 실험결과와 비교하였다. 그 결과, 2성분 혼합물에서 DMF 몰분율이 약 0.7 이하인 경우는 혼합물의 인화점이 25 ℃이하로 관측되어, 고인화점 물질의 혼합에 의한 인화점상승에 대한 효과가 작은 것으로 나타났다. 그리고 평균온도차이를 이용하여 각 모델별 예측값을 평가한 결과, 르샤틀리에 모델의 경우가 1.95 ℃로 측정값에 가장 근사한 것으로나타났다.

      • KCI등재

        CADASIL에서 고혈압이 열공경색과 뇌미세출혈의 발병위치에 미치는 영향

        이정석,오정환,송숙근,최재철,강사윤,강지훈 대한치매학회 2014 Dementia and Neurocognitive Disorders Vol.13 No.4

        Background: Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small vessel disease caused by mutations in the Notch3 gene. Lacunes may reflect occlusive type microangiopathy. However, cerebral microbleeds (CMBs) may reflect bleeding-prone microangiopathy. In the present study, we aimed to determine whether hypertension influence the distribution and severity of lacunes and CMBs in patients with CADASIL. Methods: The study population comprised 85 patients who underwent brain MRI, including T1-weighted image, susceptibility weighted image (SWI), and fluid attenuated inversion recovery (FLAIR) image. The patients were divided into two groups depending on the presence or absence of hypertension. In the first, demographic factors, and MRI findings were compared between CADASIL patients with and without hypertension. In the second, we undertook a region by region comparison of number of patients with lacunes or CMBs. Results: The hypertensive group showed a higher incidence of CMBs in lobar area (p<0.001) and basal ganglia (p=0.014). CMBs tend to be observed more frequently in the thalamus (p=0.058), brainstem (p=0.057), and cerebellum (p=0.052) in the hypertensive group. However, hypertensive group demonstrated a higher incidence of lacunes just in lobar area (p=0.040). Conclusions: Our findings suggest that CMBs may be a more sensitive neuroimaging marker of hypertensive arteriopathy in patients with CADASIL.

      • KCI등재

        쯔쯔가무시병의 질병기간에 영향을 미치는 인자

        이정석,강지현,조병기,유병연 대한가정의학회 2007 Korean Journal of Family Medicine Vol.28 No.10

        Factors Affecting Disease Duration in Patients with Tsutsugamushi DiseaseJeong-Seok Lee, M.D., Jee-Hyun Kang, M.D.†, Byoung-Ki Cho, M.D., Byung-Yeon Yu, M.D.Background: Tsutsugamushi disease, which is caused by Orientia tsutsugamushi, is an acute febrile illness transmitted by infected mites. Recently, the incidence rate has been increased especially in the Daejeon and Chungcheongnam-do. We analyzed the patients with tsutsugamushi disease, who lived in Daejeon and Chungcheongnam-do, to find out their clinical manifestations and factors affecting the disease duration. Methods: A total of 102 patients who were diagnosed with tsutsugamushi disease at the department of family medicine in a university hospital from September 2005 to November 2005 were studied. We analyzed their clinical characteristics and investigated the clinical factors associated with disease duration in tsutsugamushi disease by multiple regression analysis. The term “disease duration” was defined as the interval from symptom onset to discharge. Results: Among 102 patients, 33 were males and 69 were female, and the mean age was 57.4 years. The average interval from symptom onset to admission was 6.6 days. The average interval from symptom onset to discharge was 14.5 days. From multiple regression analysis, interval from symptom onset to admission (β=0.470, P<0.001), serum albumin level (β=3.441, P= 0.019), and abnormal findings of chest X-ray (β=2.925, P=0.021) were shown to independently contribute to disease duration (R2= 0.458). Conclusion: Disease duration is significantly correlated with clinical factors such as abnormal findings of the chest X-ray, lower serum albumin level, and longer interval from symptom onset to admission. These factors could be used as parameters of the severity of disease in patients with tsutsugamushi disease. (J Korean Acad Fam Med 2007;28:774-781) 연구배경: 쯔쯔가무시병은 Orientia tsutsugamushi의 감염으로 발생하며, 좀진드기에 의해 매개되는 급성 열성 질환이다. 최근 쯔쯔가무시병의 유병률이 증가하고 있으며 특히 대전, 충남 지역에 많은 환자가 발생하고 있다. 본 연구는 대전, 충남 지역의 쯔쯔가무시병 환자들의 임상적 특성을 분석하고, 질병기간에 영향을 미치는 요소를 알아보고자 하였다. 방법: 2005년 9월에서 11월까지 3개월 동안 대전 지역에 위치한 일개 대학병원 가정의학과에 내원하여 쯔쯔가무시병으로 진단받은 102명의 환자를 대상으로 임상적 특성을 분석하고, 다중 회귀 분석 방법을 통해 질병기간에 영향을 미치는 요소를 찾아보았다. 질병기간은 증상발생부터 퇴원까지의 기간으로 정의했다. 결과: 총 102명의 평균 연령은 57.4세였고, 여성이 69명(67.6%)으로 다소 많았다. 평균 입원기간은 7.5일이었고, 증상발생부터 내원까지의 기간은 평균 6.6일이었으며, 증상발생부터 퇴원까지의 기간은 평균 14.5일이었다. 질병기간을 종속변수로 이용하여 시행한 다중 회귀 분석에서 질병기간에 독립적인 영향을 미치는 변수는 증상발생 후 입원까지의 기간(β=0.470, P<0.001), 혈청 알부민 농도(β=-3.441, P=0.019), 흉부 엑스선 사진 이상 소견(β=2.925, P=0.021)이었다(R2=0.458). 결론: 쯔쯔가무시병의 질병기간은 입원 시 흉부 엑스선 사진상 이상 소견이 있거나 혈청 알부민 농도가 낮거나 증상발생 후 늦게 내원할수록 길어지며, 이들 변수들은 임상적으로 조기에 질환의 중증도를 판단하는 지표로 유용하게 사용할 수 있을 것이다.

      • KCI등재후보

        황복(Takifugu obscurus)에 대한 중금속, 유기주석화합물 및 다환방향족탄화수소(PAHs)의 급성 독성

        이정석,이규태,김동훈,김진형,한경남 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

        We exposed juvenile puffer fish, Takifugu obscurus(30 days after hatching) to various aqueous pollutants including 4 kinds of inorganic metals(Ag, Cd, Cu and Hg), 2 organotin compounds(tributyltin [TBT] and triphenyltin [TPhT]) and 5 polycyclic aromatic hydrocarbon(PAH) compounds(chrysene, fluoranthene, naphthalene, phenanthrene and pyrene) to estimate median lethal concentrations(LC50s) of each pollutant after the 96-hour acute exposure. Among the inorganic metals, Hg(52㎍/L; 96-h LC50) was most toxic to test animals and followed by Ag(164㎍/L), Cu(440㎍/L) and Cd(1180㎍/L). Aqueous TBT was more toxic between the two organotins; the 96-h LC50 for TBT(5.1㎍/L) was 3 times lower than that of TPhT(17.3㎍/L). The acute toxicity of PAH compounds was highest for chrysene(1.5㎍/L; 96-h LC50) and decreased in the order of pyrene(65㎍/L)>fluoranthene (158㎍/L)>phenanthrene(432㎍/L)>naphthalene(8690㎍/L). The toxicity of PAH compounds was closely related to their physico-chemical characteristics such as K_(ow) and water solubility, and well explained by simple QSAR relationship. The sensitivity of puffer fish to various inorganic and organic pollutants was generally comparable to various fish species widely used as standard test species in previous studies and further evaluation should be conducted to develop adequate testing procedures for T. obscurus when used in various toxicity tests.

      • KCI등재

        인지기능 저하에 따른 후각기능의 변화

        이정석,김상윤,김정훈 대한신경과학회 2007 대한신경과학회지 Vol.25 No.3

        Background: The aim of the current study was to investigate the changes of the olfactory function in the Korean elderly population related to cognitive decline by using the CDR (Clinical Dementia Rating scale) and KVSS Test (Korean Version of Sniffin’ Sticks Test). Methods: 41 subjects between the ages of 65-85 years, were included in this study. All subjects were screened to exclude conditions affecting olfactory functions. These subjects were divided into three groups according to CDR. 23 subjects belonged to the CDR 0 group, 9 to the CDR 0.5 group and 9 to the CDR 1 group. The KVSS Test consisted of the olfactory threshold test and olfactory identification test. Results: Significant differences were found among the CDR 0 group, CDR 0.5 group and CDR 1 group (p<0.001) in the olfactory identification test. Scores in the olfactory identification test was lower in the CDR 1 group than in the CDR 0.5 group and CDR 0 group. There were no significant differences between the scores of subjects in the CDR 0 group and those in the CDR 0.5 group on the olfactory identification test. Scores in the olfactory threshold test were not different in the CDR 0 group, CDR 0.5 group and CDR 1 groups (p>0.05). Conclusions: These results suggest that the cognitive deficits were associated with the decrease of scores in the olfactory identification test and that the olfactory identification test may have clinical utility in the diagnosis of the dementia.

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