박리성 골연골염환자 1예에 대한 증례보고

이옥진 ( Yu Chen Lee ),김빛나라 ( Bin Nara Kim ),이정민 ( Jung Min Lee ) 대전대학교 한의학연구소 2013 한의학연구소 논문집 Vol.22 No.1

Objective : The objective of this study is to observe the effect of anti-inflammatory herbal acupuncture, acupuncture, physical theraphy, external treatment, therapeutic exercise on the osteochondritis dissecans. Methods : Anti-inflammatory herbal acupuncture and acupuncture were used to treat knee pain and gait disturbance. We evaluated the patient through VAS(visual analogue scale) daily and symptoms. Results & Conclusions : After 31 days of treatment, right knee pain was decreased from VAS 10 to VAS 4, redness, burning sensation, edemaright of right knee were decreased. And the patient could walk. Oriental medicine treatment is proved to be helpful to imporve the symptoms of the osteochondritis dissecans.

세신(細辛) 주정(酒錠) 추출물(抽出物)이 LPS로 유발된 RAW 264.7 Cell의 염증 및 항산화 반응에 미치는 영향

이옥진 ( Yu Chen Lee ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.3

Objectives The purpose of this study was to investigate the Anti-oxidation and anti-inflammatory effects of ethanol extract from asiasari radix (AR) on lipopolysaccharide (LPS)-induced in RAW 264.7 Cells Methods Anti-oxidative effects of AR were measured by scavenging activities of 1,1-diphenyl- 2-picryl-hydrazyl (DPPH), 2,2``-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and production of reactive oxygen species (ROS) in RAW 264.7 cells. Anti-inflammatory effects of AR were measured by mediators including nitric oxide(NO), interleukin- 1β (IL-1β), interleukin-6 (IL-6), tumor necosis factors-α (TNF-α) and iNOS, IL-1β, IL-6, TNF-α mRNA expression in RAW 264.7 cells. Results Total phenolic content was expressed 28.77±1.67. DPPH radical Scavenging was increased depend on AR ethanol extract. ABAT radical Scavenging was increased depend on AR ethanol extract. Production of ROS was significantly decreased by AR ethanol extract on concentration of 100 (μg/ml). Production of NO was significantly decreased by AR ethanol extract on concentration of 100 (μg/ml). Production of IL-1β, interleukin-6 and TNF-α were increased depend on AR ethanol extract. And Production of interleukin- 6, TNF-α were significantly decreased AR ethanol extract. iNOS, IL-1β, IL-6, TNF- α mRNA expression of RAW 264.7 cells was increased depend on AR ethanol extract. Conclusions According to this study, AR ethanol extract has anti-oxidative and anti-inflammatoy effects. (J Korean Med Rehab 2014;24(3):99-110)

교통사고 후 발생한 경항통 환자에 대한 황련해독탕약침과 분리정제봉약침의 치료 효과 비교연구: 무작위 배정

이옥진 ( Yu Chen Lee ),남대진 ( Dae Jin Nam ),허건 ( Gun Huh ),이재은 ( Jae Eun Lee ),김빛나라 ( Bin Na Ra Kim ),송은모 ( Eun Mo Song ),이은정 ( Eun Jung Lee ),이정민 ( Jung Min Lee ),오민석 ( Min Seok Oh ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4

ObjectivesThe purpose of this study is to compare the effects of HWANGRY-UNHAEDOKTANG Pharmacopuncture and Essential Bee Venom pharmacopuncture on cervical pain caused by traffic accident.MethodsThe clincal study was conducted to traffic accident patients who had admitted to Dae-Jeon University Cheonan Oriental Hospital from May 17, 2014 to September 2, 2014. The patients were simple randomization and divided into two groups. In one group, patients were treated with the oriental medicine and HWANGRYUNHAEDOKTANGPharmacopuncture, While in the other group, patients were treated with the oriental medi-cine therapy and Essential Bee Venom pharmacopuncture therapy. visual analogue scale (VAS), pain threshold and neck disablity index (NDI) were used To estimate the efficacy of Pharmacopuncture treatment.Results1) HWANGRYUNHAEDOKTANG Pharmacopuncture Group showed significant decrease of VAS and NDI after 3rd times treatment than before treatment (p<0.001). Essential Bee Venom Pharmacopuncture showed significant decrease of VAS, NDI and improve ment of pain threshold after 3rd times treatment than before treatment (p<0.01, p<0.001). 2) There was no significant difference between HWANGRYUNHAEDOKTANGPharmacopuncture group and Essential Bee Venom Pharmacopuncture group in VAS, pain threshold and NDI. ConclusionsWe found out that HWANGRYUNHAEDOKTANG Pharmacopuncture and Essential Bee Venom Pharmacopuncture treatment are considered to be effective and useful in cervical pain caused by traffic accident. (J Korean Med Rehab 2014;24(4): 145-153)

요추부 염좌 환자에서 다용 경혈에 대한 침치료와 자가운동요법이 미치는 효과

이옥진 ( Yu Chen Li ),허건 ( Gun Huh ),남대진 ( Dae Jin Nam ),이은정 ( Eun Jung Lee ),오민석 ( Min Seok Oh ) 대전대학교 한의학연구소 2014 혜화의학회지 Vol.22 No.2

Objective : The purpose of this study was to investigate the effects of acupuncture treatment on frequently adopted acupuncture point and self exercise therapy for lumbar sprain patient Methods : For this study, a retrospective chart review was conducted. Data are derived from lumbar sprain patients who have received hospital treatment in Daejeon Univ. Cheon-Ahn Korean Hospital. All patients were treated with acupuncture treatment on high frequency acupuncture point (BL25, BL23, BL24, GB30, BL40, BL26, BL60, GB34), physical therapy and herbal medicine and self exercise therapy(Swiss ball exercise, Lumbar stabilization exercise.) We measured visual analogue scale(VAS), Oswestry disability index(ODI), Pain threshold twice(pre-treatment and post-treatment) on 1st day and 5 days later. Results : After being treated, lumbar sprain patients were meaningful improved in VAS, ODI, pain threshold The VAS score, ODI score were statistically decreased after treatment and the pain threshold was statistically increased after treatment. Conclusion : In this study, treatment on frequently adopted acupuncture point and self exercise therapy were effective on lumbar sprain patient.

반복적으로 시행한 온천요법이 경항통에 미치는 영향

이옥진 ( Yu Chen Li ),최보미 ( Bo Mi Choi ),장선정 ( Sun Jeong Jahng ),안택원 ( Taek Won Ahn ),이정민 ( Jung Min Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

ObjectivesThe purpose of this study was to investigate the clinical effects of repeatedly performed of balneotherapy on cervical pain. MethodsWe investigate 19 cervical pain subjects in this study. Subjects took 5 session of balneotherapy once a week during 5 weeks. Each session consisted of 15 minutes of high pressure underwater shower (32~36oC) and another 15 minutes of whole body bathing (32~40oC). To evaluate the efficiency of balneotherapy visual analogue scale (VAS) and pain threshold were applied before treatment and after 1st, 2nd, 3rd, 4th, 5th treatment. Then the results were analysed. Results1) The average of VAS significantly decressed from 59.11±14.67 to 33.95± 20.988 after 5 weeks of balneothreapy treatment (p<0.001). 2) The average of pain threshold significantly increased from 5.76±1.294 lbf to 8.74±1.126 lbf after 5 weeks of balneothreapy treatment (p<0.001). ConclusionsBalneotherapy has clinical effscts of pain reduction on cervical pain subjects. Balneotherapy can be used in addition to the Oriental physiotherapy for high effective treatment on cervical pain. Further clinical studies are required to verify these findings. (J Korean Med Rehab 2013;23(3):141-148) ObjectivesThe purpose of this study was to investigate the clinical effects of repeatedly performed of balneotherapy on cervical pain. MethodsWe investigate 19 cervical pain subjects in this study. Subjects took 5 session of balneotherapy once a week during 5 weeks. Each session consisted of 15 minutes of high pressure underwater shower (32~36oC) and another 15 minutes of whole body bathing (32~40oC). To evaluate the efficiency of balneotherapy visual analogue scale (VAS) and pain threshold were applied before treatment and after 1st, 2nd, 3rd, 4th, 5th treatment. Then the results were analysed. Results1) The average of VAS significantly decressed from 59.11±14.67 to 33.95± 20.988 after 5 weeks of balneothreapy treatment (p<0.001). 2) The average of pain threshold significantly increased from 5.76±1.294 lbf to 8.74±1.126 lbf after 5 weeks of balneothreapy treatment (p<0.001). ConclusionsBalneotherapy has clinical effscts of pain reduction on cervical pain subjects. Balneotherapy can be used in addition to the Oriental physiotherapy for high effective treatment on cervical pain. Further clinical studies are required to verify these findings. (J Korean Med Rehab 2013;23(3):141-148)

Guilain-Barre Syndrome 환자에 대한 한방치료 1례

허건 ( Gun Huh ),이옥진 ( Yu Chen Lee ),이정민 ( Jung Min Lee ),오민석 ( Min Seok Oh ) 대전대학교 한의학연구소 2014 한의학연구소 논문집 Vol.23 No.1

Objective : This is clinical about the Wei syndrome(위證)-patient diagnosed as Guillian-Barre Syndrome(GBS). GBS, What is called acute inflammatory plolyneuritis, is a disorder in which the body``s immune system attacks parts of peripheral nerve system. It is characterized by the rapid onset of weakness, paralysis of the legs, arms, breathing muscles and face. But the analysis of CSF and electical tests on nerve and muscle function can be performed to confirm the diagnosis. Most cases occur shortly after a viral infection. Methods & Result : This is the clinical report about the one patient diagnosed as Guillain-Barre Syndrome. The patient, 46-year-old men had weakness in both legs and arms after divertculitis. His weakness and general condition improved after oriental medical treatment and acupuncture. As a result, symptoms were improved remarkably. Conclusion : We report that we had good effects of oriental medical treatment on Guillain-Barre Syndrome.

원발성 월경통의 추나 치료에 대한 체계적 문헌 고찰

서하라 ( Ha-ra Seo ),이옥진 ( Yu-chen Li ),이재은 ( Jae-eun Lee ),김명규 ( Myoung-kyu Kim ) 대한한의학회 한방재활의학과학회 2017 한방재활의학과학회지 Vol.27 No.3

Objectives The purpose of this study is to evaluate the effectiveness of Chuna therapy for primary dysmenorrhea. Methods Researchers searched on 7 electronic databases (Pubmed, National Digital Science Library, China National Knowledge Infrastructure, Wangfang med online, Korean Studies Information Service System, Research Information Sharing Service and Oriental medicine Advanced Searching Integrated System). The search included Korean, English, Chinese reports and there was no limit on the search period. All of randomized controlled clinical trials (RCTs) that used Chuna manual therapy for primary dysmenorrhea were selected. Results 27 RCTs met required condition. Meta-analysis showed positive results for Chuna manual therapy for primary dysmenorrhea in terms of therapeutic effects and reduction of symptom scores compared to west medicine, herbal medicine, acupucture and other treatments. Conclusions Above results showed that performing chuna is effective in treating dysmenorrhea. However, in some studies, there was no statistic significance between the experimental group and the control group. Also, according to Cochrane Risk of Bias (RoB) evaluation method, quality of the studies were not high enough. Since most of the materials were in Chinese, more high-quality clinical trials about Chuna therapy for primary dysmenorrhea are needed in Korea. (J Korean Med Rehabil 2017;27(3):81-93)

5주간의 온천요법 전후 요통의 통증변화에 관한 임상연구

신재화 ( Jae Hwa Shin ),이옥진 ( Yu Chen Li ),최보미 ( Bo Mi Choi ),안택원 ( Taek Won Ahn ),이정민 ( Jung Min Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

ObjectivesThe aim of this clinical study was to find out the changes of self-reported pain intensity before and after balneothrapy in participants with low back pain. MethodsIn this study 20 participants with low back pain went through 5 weeks of balneothrapy course, once in a week. Each week visual analogue scale (VAS) and pain threshold were measured before and after balneothrapy, which consisted of 30 minutes of high pressure underwater shower (32~36oC) and another 30 minutes of whole body bathing (32~40oC). Results1. The average of VAS significantly decreased from 64.00±16.35 to 34.00±15.69 after 5 weeks of balneothreapy (p<0.001). 2. The average of pain threshold significantly increased from 8.31±2.52 lbf to 9.53±3.11 lbf after 5 weeks of balneothreapy (p<0.05). ConclusionsThe results showed that 5 weeks of balneotherapy had significant effect on alleviating pain in low back pain participants, which means balneothreapy may be used as a complementary treatment on musculoskeletal diseases and other chronic diseases. Further studies are anticipated in the future to find out other various effects of balneothrapy. (J Korean Med Rehab 2013;23(3):133-140) ObjectivesThe aim of this clinical study was to find out the changes of self-reported pain intensity before and after balneothrapy in participants with low back pain. MethodsIn this study 20 participants with low back pain went through 5 weeks of balneothrapy course, once in a week. Each week visual analogue scale (VAS) and pain threshold were measured before and after balneothrapy, which consisted of 30 minutes of high pressure underwater shower (32~36oC) and another 30 minutes of whole body bathing (32~40oC). Results1. The average of VAS significantly decreased from 64.00±16.35 to 34.00±15.69 after 5 weeks of balneothreapy (p<0.001). 2. The average of pain threshold significantly increased from 8.31±2.52 lbf to 9.53±3.11 lbf after 5 weeks of balneothreapy (p<0.05). ConclusionsThe results showed that 5 weeks of balneotherapy had significant effect on alleviating pain in low back pain participants, which means balneothreapy may be used as a complementary treatment on musculoskeletal diseases and other chronic diseases. Further studies are anticipated in the future to find out other various effects of balneothrapy. (J Korean Med Rehab 2013;23(3):133-140)

족관절 염좌의 봉독 약침 치료에 대한 체계적 문헌 고찰

구지향 ( Ji-hyang Gu ),이옥진 ( Yu-chen Li ),조동찬 ( Dong-chan Jo ),이은정 ( Eun-jung Lee ) 대한한의학회 한방재활의학과학회 2018 한방재활의학과학회지 Vol.28 No.3

Objectives To evaluate the evidence supporting the effectiveness of bee venom acupuncture for ankle sprain. Methods We conducted search across 11 electronic databases (Pubmed, EMBASE, Cochrane CENTRAL [CENTRAL], KoreaMed, Kmbase, Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], Korea Institute of Science and Technology Information [KISTI], China National Knowledge Infrastructure [CNKI], Wanfang and Chinese Scientific Journals Database [VIP] database) to find clinical trials that used bee venom acupuncture as treatment for ankle sprain. The methodological quality of randomized controlled clinical trials (RCTs) were assessed using the Cochrane Risk of Bias (RoB) tool, while non-randomized controlled clinical trials (NRCTs) were assessed using the Cochrane Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Four RCTs and one nRCT met our inclusion criteria. Almost studies showed that bee venom acupuncture has positive effect on ankle sprain. 4 studies of same intervention and control included in the meta-analysis. When comparing bee venom acupuncture and acupuncture with acupuncture, the effect size of standardized mean difference (SMD) was -0.19 (95% confidence interval [CI]: -1.95∼1.56, Z=0.55, p=0.83). And when comparing bee venom acupuncture with acupuncture, the effect size of SMD was -0.17 (95% CI: -0.65∼0.31, Z=0.71, p=0.48). Conclusions Although our systematic review found encouraging but limited evidence of bee venom acupuncture for ankle sprain, most of the studies included in the analysis were evaluated as methodologically high risk of bias. From now on further well-designed RCTs should be encouraged. (J Korean Med Rehabil 2018;28(3):55-66)

한방복합치료를 병행한 도인운동요법이 요통환자의 통증 및 기능 개선에 미치는 영향

최봉석(Bong Seok Choi),이은정(Eun Jung Lee),이옥진(Yu Chen Li),이정민(Jung Min Lee),김은석(Eun Seok Kim),송광찬(Gwang Chan Song),정인철(In Chul Jung),오민석(Min Seok Oh) 한의병리학회 2018 동의생리병리학회지 Vol.32 No.1