피하 주머니 이식술을 이용한 수부 무지 첨부 재건술 - 2예 보고 -

이영근,문영재,이준모,Lee, Young-Keun,Moon, Young-Jae,Lee, Jun-Mo 대한미세수술학회 2011 Archives of reconstructive microsurgery Vol.20 No.2

Purpose: The subcutaneous pocket graft of the thumb tip amputation across or proximal to the lunula is chosen in case of impossible microvascular anastomosis and in patient who strongly desired to preserve the thumb tip after failed replantation. Materials and Methods: Two patients who underwent a subcutaneous pocket graft for a thumb tip reconstruction between August 2008 and November 2009 were reviewed retrospectively. They were all males with a mean age at the time of surgery of 48 years and had sustained complete thumb tip amputations across or proximal to the lunula. In one case, the microsurgical replantation was not feasible and the other one revealed arterial insufficiency at the 7th day after microsurgical replantation. Results: Authors had experienced 2 cases of flaps which survived completely. The results of sensibility was good, the range of motion at interphalangeal joint and tip to tip pinch was acceptable and color mismatch and loss of thumb finger nail was unacceptable after more than 1 year follow up with conventional successful thumb tip replantation. Conclusion: The subcutaneous pocket graft could be chosen in thumb tip amputation in case of impossible microvascular anastomosis as well as who strongly desires to preserve thumb tip after failed replantation.

유리 동맥화 정맥 피판을 이용한 수지 연부조직 결손의 재건

이영근,우상현,이준모,안희찬,천호준,Lee, Young-Keun,Woo, Sang-Hyun,Lee, Jun-Mo,Ahn, Hee-Chan,Cheon, Ho-Jun 대한미세수술학회 2010 Archives of reconstructive microsurgery Vol.19 No.1

Purpose: To report the clinical results of the use of arterialized venous free flaps in reconstruction in soft tissue defects of the finger and to extend indications for the use of such flaps based on the clinical experiences of the authors. Materials and Methods: Eighteen patients who underwent arterialized venous free flaps for finger reconstruction, between May 2007 and July 2009 were reviewed retrospectively. The mean flap size was 4.7${\times}3.2$ cm. The donor site was the ipsilateral volar aspect of the distal forearm in all cases. There were 8 cases of venous skin flaps, 5 cases of neurocutaneous flaps, 4 cases of tendocutaneous flaps, 1 case of innervated tendocutaneous flap. The vascuality of recipient beds was good except in 4 cases (partial devascuality in 2, more than 50% avascuality (bone cement) in 2). Results: All flaps were survived. The mean number of included veins was 2.27 per flap. Mean static two-point discrimination was 10.5 mm in neurocutaneous flaps. In 3 of 5 cases where tendocutaneous flaps were used, active ROM at the PIP joint was 60 degrees, 30 degrees at the DIP joint and 40 degrees at the IP joint of thumb. There were no specific complications except partial necrosis in 3 cases. Conclusions: An arterialized venous free flap is a useful procedure for single-stage reconstruction in soft tissue or combined defect of the finger; we consider that this technique could be applied to fingers despite avascular recipient beds if the periphery of recipient bed vascularity is good.

수지 재건시 불충분한 혈행상태의 수혜부에 시행한 동맥화 정맥 유리 피판술

이영근,박기태,이준모,박혁,Lee, Young-Keun,Park, Ki-Tae,Lee, Jun-Mo,Park, Hyuk 대한미세수술학회 2012 Archives of reconstructive microsurgery Vol.21 No.2

Purpose: Arterialized venous flap is useful for reconstruction of the traumatic soft tissue defect in fingers, but insufficient circulation of the traumatic fingers makes surgeons annoying to use the flap. We have grafted flaps in 7 fingers with insufficient vascular bed hoping to expanded the category of the flap. Materials and Methods: Arterialized venous flap have transplanted in 7 fingers from March 2008 through February 2010 and followed up for 4 to 16 months(average 7.2 months). They were all male with a mean age at the time of surgery was 33. The main injury was crushing in 4 degloving, contact burn and saw injury was I respectively. Time interval from injury to flap transplantation was average 3.1. weeks(3 days to 6 weeks). Designed flap size ranges from $8cm{\times}3.5cm$to $4cm{\times}3cm$. Vessel type of flap was one artery with two veins were 5 cases and one artey with one vein 2. Flap type was cutaneous in 3, tendocutaneous 2, neurotendocutaneous 1 and neurocutaneous 1. The circulation state of recipient site was avascular in 2 cases, insufficiency 3 and tip avascular 2. Results: Arterialized venous flap was complete survived in 2 cases, partial necrosis(less than 10%) 3 and failed in 2. Conclusion: An arterialized venous free flap could be a useful procedure for reconstruction in soft tissue or combined defect of the finger despite an avascular or insufficient vascular beds if the recipient beds were free from infection.

돼지여포의 퇴화과정 중 여포액 내 스테로이드 호르몬 양의 변화

이영근,윤용달,Lee, Young-Keun,Yoon, Yong-Dal 대한생식의학회 1985 Clinical and Experimental Reproductive Medicine Vol.12 No.1

In order to study the mechanism of follicular atresia, the follicles of the porcine ovary were isolated according to the presence or absence of the corpus luteum and their size, and then classified to the normal? or atretic?follicle on the morphological observation such as the transparency, the vascularization of follicle, the nuclear phase of oocyte, and the homogeneity of the granulosa cell layer. The viability of granulosa cells was examined. The concentrations of progesterone ($P_4$), testosterone (T), and estradiol-17 beta ($E_2$) in each follicular fluid were estimated by the radioimmunoassay. The viability of granulosa cells in the atretic follicle was much lower than that of the normal one. The concentration of each steroid hormone increased as the follicular size was increased, was not different in quantity between the normal- and the atretic follicle of which diameter was below 3mm, and were much higher in the atretic follicle than those in the normal one of which diameter was above 7mm. The ratio of the concentration of E2 to T in the large atretic follicle valued higher than that in the normal one, but smaller in the small and medium atretic follicle than that in the normal one. The present study suggests that the mechanism of atresia of the large follicle may be different from that of the small and the medium follicle and that the amount of steroid hormones regarded as the one of the criteria for the atretic follicles.

방사선을 이용한 느타리 ( Pleurotus ostreatus ) 의 섬유소 분해 변이주 선발

이영근,장화형,김원록,이창주,김진규 ( Young Keun Lee,Hwa Hyoung Chang,Won Rok Kim,Chang Joo Lee,Jin Kyu Kim ) 한국환경생물학회 1998 환경생물 : 환경생물학회지 Vol.16 No.2

To isolate the cellulolytic variants, the basidiospores of Pleurotus ostreatus were irradiated at the dose of 1Gy∼20kGy of gamma-ray. After irradiation the germination and survival rates of basidiospores were observed and the activity of extracellular enzyme was determined by means of MUF-substrate method. The 45 variants showed various levels of mycelial growth rate and cellulolytic activity on solid media and vari ous levels of activities of the extracellular enzymes. We have isolated highly cellulolytic variants. 1.5KG-2 and 2KG-2. among the above variants. It is suggested that the isolated 2 variants could be applied usefully to reuse and/or recycle of the cellulosic bioresources.

수근부 자해열상의 수술적 치료

이영근,박찬일,이준모,Lee, Young-Keun,Park, Chan-Il,Lee, Jun-Mo 대한미세수술학회 2012 Archives of reconstructive microsurgery Vol.21 No.1

Purpose: To report clinical appearances and the outcomes of patients treated for wrist laceration with suicidal intent. Materials and Methods: Between March 2005 and February 2008, patients with wrist laceration were treated at our center. Among them, 14 patients with suicidal intent were reviewed retrospectively. They were 8 females and 6 males with a mean age of 33 years at the time of treatment. The side of injured wrist, injured structures, suicidal instrument, the time of injury, a suicidal motive, drug or alcohol abuse or not, indication of combined psychiatric disease, the duration of postoperative treatment, and the results of treatment were analyzed. Results: The injured wrist was the left one in 13 cases (93%), and knife wounds in 11 cases (79%) was the most frequent mechanism of injury. An average of 4.6 structures were injured including 3.5 tendons, 0.57 nerves and 0.5 arteries. The most frequently injured structures were the palmaris longus (71%), FCU (50%), FCR (43%), FDS 3 (36%), FDS 2, median nerve, and ulnar artery (each 29%). Simultaneous injury of both median and ulnar nerves occurred in 3 cases (21%), and simultaneous injury of both radial and ulnar artery occurred in 1 case (7%). The injury time was the night in 12 cases (86%), and the most frequent suicidal motive was human relations such as lover or spouse in 12 cases (86%). In 9 cases (64%), the injured were in a drunken state, 3 cases (21%) had been treated for a psychiatric disease at the time of the injury. The durations of postoperative treatment were an average of 5 days of admission and 1 day follow up. Only 1 case results could be evaluated. Conclusions: Patient's poor compliance in wrist laceration with suicidal intent should be expected and these characteristics may affect the management plan.

노인건강과 영양

이영근(Lee Young Keun) 한국노년학회 1984 한국노년학 Vol.4 No.1

A number of aged-related physiological and biochemical changes and many social, psychological, physical and economic factors can influence nutritional needs, alter dietary intake and the utilijation of nutrients and compromise the nutritional status of the elderly. Therefore, in order to meet the problem of nutrition having a great influence on their health and prolonging we should make the nutrition plan as such: 1. With advancing age, lean body mass, basal metabolic rate and physical activity all decline. This results in a lower expenditure of energy which means that the elderly need to consume fewer Calories to maintain body weight. Some elderly remain very active throughout life, others become comparatively inactive but may retain their earlier patterns of eating and consume more Calories than can be utilized, thus leading to overweight. Obesity is a major problem, and for the elderly it can present an increasing hazard to mobility and increase the tendency to diabets and coronary heart disease. The problem for many of the elderly is to decrease the Calorie stake or quantity food consumed and yet maintain an adequate intake of each of the nutrients. 2. They should take the food which is easy to be digestive considering their digestive and absorbing is much lower than younger. As they have bad tooth, their all food must not impose chewing by cooking all softly. Thus they must be able to take high Calory by small amount. 3. They should escape the salty food. Korean people take 20-30g a day in stead of necessary amount of adult 10-15g a day. It is the very bad habit of korean food life and an urgent problem. The excessive taking of salt causes all kinds of chronic disease and adult disease, so their taking salt of amount must be reduced by 10g a day. 4. They should take fresh fruit, vegetable and seaweeds. As food absorbing rate of the elderly is low and their excretive amount is much, all kinds of vitamin and mineral is easy to be lack to them. They also often have contstipation by diminishing of their mucous secretion. Accordingly they should take enough the fruit, vegetable and seaweeds helping their liquid operation and their excretive operation of motions smoothly, and they also take water and juice. 5. The meat is good for the elderly in order to take the animal protein of good quality, but the excessive intake is rather bad to them. The fish is good for them on account it has much unsaturated fatty acid. It is good for their hearth to eat an egg, an half cake of bean-curd and an half fish a day. 6. It is good for the elderly to take the liver, the treasure of all kinds of nurishment, a week, by using cooking of escaping the small of liver. 7. We should change the recognition that milk is good for only children. It is good food for the health of woman and the elderly as well as that of grown-up. Therefore, it is good to have two cups of milk everyday.

단기간의 나트륨 섭취수준이 정상 성인 여성의 혈청 지질과 혈당에 미치는 영향

이영근(Young-Keun Lee),승정자(Chung-Ja Sung),최미경(Mi-Kyeong Choi),이윤신(Yoon-Shin Lee) 한국식품영양과학회 2002 한국식품영양과학회지 Vol.31 No.6

본 연구는 나트륨 섭취수준이 혈중 지질과 혈당에 미치는 영향을 규명해보기 위하여 정상 성인 여성 20명을 대상으로 고나트륨식과 저나트륨식을 각각 6일씩 공급한 후 혈중 지질, 혈당 및 기타 혈액성상의 변화를 비교분석하였다. 그 결과를 요약하면 다음과 같다. 연구대상자들의 평균연령은 22.9±2.5세였으며 평균 체중과 신장은 54.7±6.6 kg과 160.0±4.8 cm였고 수축기/이완기 혈압은 110.3±7.7/67.5±9.7 mmHg로 정상범위에 속하였다. 나트륨 섭취수준에 따른 평균 체중의 변화는 고나트륨식이 54.7±6.4 kg으로 저나트륨식의 53.8±6.2 kg보다 유의하게 높았다(p<0.001). 평균 신장은 고나트륨식과 저나트륨식간에 유의적인 차이를 보이지 않았으며 체질량지수는 고나트륨식보다 저나트륨식을 실시한 후 유의하게 감소하였다(p<0.001). 수축기혈압은 고나트륨식과 저나트륨식에 따라 유의한 차이가 없었으나, 이완기혈압은 고나트륨식(65.5±8.3 mmHg)보다 저나트륨식(60.8±8.6mmHg) 이후 유의하게 감소하였다(p<0.05). 혈청 콜레스테롤, LDL-콜레스테롤, HDL-콜레스테롤 함량은 나트륨 섭취수준에 따라 유의적인 차이를 보이지 않았으나 중성지질은 고나트륨식의 89.4±27.3 mg/dL보다 저나트륨식이시 73.8±12.5 mg/dL로 유의하게 감소하였다(p<0.05). 혈청 아포 A-I은 고나트륨식의 183.7±32.7 mg/dL보다 저나트륨식에서 167.5±22.8 mg/dL로 유의적으로 감소하였으나(p<0.001), 아포 B는 고나트륨식의 83.3±13.9 mg/dL보다 저나트륨식에서 90.8±12.9 mg/dL로 유의하게 증가하였다(p<0.001). 아포 A-I/B는 저나트륨식이 1.9±0.2로 2.2±0.3을 보인 고나트륨식보다 유의하게 낮았으나(p<0.001), AI(atherogenic index)는 나트륨 섭취수준에 의한 영향을 받지 않았다. 혈액 응고시간으로 thrombin time과 prothrombin time은 저나트륨식이 각각 9.6±1.1초, 11.6±0.7초로 나타나 고나트륨식의 11.3±1.3초, 12.0±0.4초보다 유의하게 빠른 것으로 나타났다(p<0.001, p<0.05). 나트륨 섭취수준에 따른 혈당 농도는 고나트륨식과 저나트륨식간에 유의한 차이가 없었으나, 인슐린 함량은 저나트륨식이 10.3±5.0 μIU/mL로 고나트륨식의 6.0±2.6 μIU/mL보다 유의하게 높았다(p<0.01). 이상의 결과를 종합할 때 저나트륨식에서 이완기 혈압, 혈청 중성지질, 아포A-I, 혈액 응고시간은 감소되었으나, 혈청 아포 B와 인슐린함량은 유의하게 증가되어 지속적인 저나트륨식 처방시 지질과 당질대사의 변화를 초래할 가능성이 있는 것으로 보여진다. 따라서 혈압 저하를 목적으로 하는 나트륨 제한식의 실시는 다양한 체내의 생화학적 변화를 고려해서 이루어져야 할 것이며, 앞으로 이에 대한 보다 다각적인 연구가 요구된다. This study was conducted to investigate the effect of sodium intake on serum lipids and glucose. 20 young adult women were fed the diets containing 290.5 mEq (high-Na diet) and 51.3 mEq (low-Na diets) Na for 6 days, respectively. Serum lipids, glucose, and other parameters after high-Na diet and low-Na diet were compared. The results would be summarized as follows. The mean age, body weight, height, and blood pressure of the subjects were 22.9±2.5 years, 54.7±6.6 kg, 160.0±4.8 cm, 110.3±7.7/67.5±9.7 mmHg, respectively. Body weight, BMI, and diastolic blood pressure were significantly higher at the end of high-Na diet than of low-Na diet (p<0.001, p<0.001, p<0.05). However, there were not significantly different in height and systolic blood pressure between high- and low-Na diet. Serum cholesterol, LDL-cholesterol, and HDL-cholesterol were not significantly different with Na intakes. Serum triglyceride was significantly higher at the end of high-Na diet than of low- Na diet (p<0.05). Serum apo A-I was significantly decreased in low-Na diet, while apo B was increased (p<0.001, p<0.001). Thrombin time and prothrombin time, blood aggregation time were significantly faster following low-Na diet (p<0.001, p<0.05). There was not significantly different in serum glucose between high- and low-Na diet. However, serum insulin was significantly higher following low-Na diet (p<0.01). It is concluded that diastolic blood pressure, serum triglyceride, serum apo A-I, blood aggregation time were decreased in low-Na diet, while serum apo B and serum insulin were increased. These results suggest that Na-restricted diet affects not only blood pressure but other biochemical parameters in blood. Therefore, for the patients who need restricted Na diet, it would be suggested that various biochemical changes should be carefully considered along with dietary Na manipulation.

묵은 배추종자의 발아와 생육에 미치는 저선량 γ 선 효과

이영근(Young Keun Lee),김재성(Jae Sung Kim),백명화(Myung Wha Back),이영복(Young Bok Lee),박영선(Young Sun Park) 한국환경생물학회 1999 환경생물 : 환경생물학회지 Vol.17 No.1

To investigate the stimulating effects of the low-dose radiation, the seeds of chinese cabbages(Brassica campestris L. cv. Hanyoreum and cv. Tropic emperor) were irradiated at the dose of 0.5㏉∼20㏉ with the γ-ray radition. In case of `Hanyoreum` cultivar, there were no significant promoting effects on the germination rate except the 0.5㏉ irradiated group. The increase in seedling height and fresh weight in 8㏉ and 12㏉ irradiated groups was 20% and 40%, respectively, which suggested the stimulating effect of the low-dose radiation on the early growth. In case of `Tropic emperor` cultivar, the germination rate of 1㏉ irradiated group increased approximately 10% and the seedling height and fresh weight of 1㏉ and 12㏉ irradiated group in the greenhouse 20% on the average, and plant height and fresh weight of 0.5㏉ and 4㏉ irradiated group in the field increased 10% and 20% on the average, respectively.

Cationic / Anionic IPN Membranes for the Pervaporation of Ethanol - Water Mixture

이영근(Young Keun Lee),김성철(Sung Chul Kim) 한국고분자학회 1988 한국고분자학회 학술대회 연구논문 초록집 Vol.1988 No.4