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      • SCOPUSKCI등재

        한우의 림프절내 림프구양 세포에서 Theileria sergenti schizonts의 검출

        이승옥,주묵,권오덕,박진호,박상열,Lee, Seung-ok,Lee, Joo-mook,Kwon, Oh-deog,Park, Jin-ho,Park, Sang-youl 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.1

        The life cycle of Theileria sergenti(T sergenti) in cattle, especially Korean native cattle, was not proved clearly. To find schizont stage in the life cycle of T sergenti in Korean cattle, T sergenti schizonts in the cells of parotid lymph nodes from 10 adult Korean cattle were examined. Lymphoid cells which were separated from these lymph nodes were cytocentrifuged to observe the parasites in the cells. T sergenti schizonts were detected in the cells of lymph nodes of 6 cattle out of them by IFA(Indirect Fluorescent Antibody) test and Giemsa stain. By peroxidase stain, the cells which contain schizonts were proved lymphoid cells. T sergenti schizonts identified by IFA test were able to be restained by Giemsa stain. Also, merozoites were observed in peripheral blood of the same 6 cattle that had schizonts, by giemsa stain, but not observed in the 4 cattle that had not been detected schizonts. As a part of life cycle of T sergenti, schizonts were observed in the lymphoid cells of Korean cattle.

      • KCI등재
      • KCI등재
      • KCI등재

        종설 : 간흡충과 담관암: 발암 기전

        이승옥 ( Seung Ok Lee ),김성훈 ( Seong Hun Kim ) 대한내과학회 2011 대한내과학회지 Vol.80 No.3

        It has been clarified that chronic infection with viruses such as hepatitis B virus, bacteria such as Helicobacter pylori and parasites contribute to carcinogenesis in human. Three helminth infections have been classified as definitely carcinogenic to humans (group I carcinogens), namely Schistosoma haematobium, which is associated with urinary bladder cancer and liver flukes Clonorchis sinensis and Opisthorchis viverrini associated with cholangiocarcinoma of the liver. Opisthorchis viverrini which has been extensively studied the association with cholangiocarcinoma is endemic in Southeast Asian countries including Thailand, Vietnam and Cambodia. Clonorchis sinensis infection which is common in rural areas of Korea and China has also been reported its definite association with cholangiocarcinoma. Carcinogenesis associated with liver flukes infections is a complex process hard to be studied because of long latency period and numerous other factors can play a role although chronic inflammation has been known as a key feature. Mechanical injury from the activities of migrating and sucking flukes contributes to biliary damage and chronic inflammation. The liver fluke also secretes or excretes metabolic products, some of which are highly immunogenic, toxic and promoting biliary epithelial cell proliferation. Host immune responses and immunopathological processes are also likely associated with chronic inflammation and carcinogenesis. Escape from host anti-tumor immune response and shift to Th2 response of Th1-Th2 balance are related with carcinogenesis. Biliary cell and its DNA damage can be induced by oxygen free radicals such as nitric oxide released from effector cells activated by inflammatory cytokines. Exogenous carcinogen suchas nitrosamine seemed also closely related with cholangiocarcinoma development in liver fluke infected individuals. In this paper, various and stepwise mechanisms of carcinogenesis by liver flukes and its potential targets can be intervene were reviewed. (Korean J Med 2011; 80:273-279)

      • KCI등재
      • KCI등재

        급성 담낭염의 치료

        이승옥 ( Seung-ok Lee ),임성균 ( Sung Kyun Yim ) 대한소화기학회 2018 대한소화기학회지 Vol.71 No.5

        Acute cholecystitis is a common serious complication of gallstones. The reported mortality of acute cholecystitis is approximately 3%, but the rate increases with age or comorbidity of the patient. If appropriate treatment is delayed, complications can develop as a consequence with a grave prognosis. The current standard of care in acute cholecystitis is an early laparoscopic cholecystectomy with the appropriate administration of fluid, electrolyte, and antibiotics. On the other hand, the severity of the disease and patient’s operational risk must be considered. In those with high operational risks, gall bladder drainage can be performed as an alternative. Currently percutaneous and endoscopic drainage are available and show clinical success in most cases. After recovering from acute cholecystitis, the patients who have undergone drainage should be considered for cholecystectomy as a definitive treatment. However, in elderly patients or patients with significant comorbidity, operational risks may still be high, making cholecystectomy inappropriate. In these patients, gallstone removal using the percutaneous tract or endoscopy may be considered. (Korean J Gastroenterol 2018;71:264-268)

      • SCOPUSKCI등재
      • KCI등재후보

        만성췌장염의 내시경적 치료

        이승옥 ( Seung Ok Lee ),김성훈 ( Seong Hun Kim ) 대한내과학회 2012 대한내과학회지 Vol.83 No.1

        Chronic pancreatitis is a debilitating disease with complications such as pancreatic duct stricture, duct stones, duct leak or fistulae, pseudocyst contributing to significant morbidity and mortality. Endoscopic intervention in patients with chronic pancreatitis compared to surgery has been known relatively safe and effective. Although there are several limitations, endoscopic intervention plays a specific role in carefully selected patients as primary interventional therapy when medical treatment was failed or patients are not suitable for surgery. In this review, we address the role of endoscopic intervention for chronic pancreatitis.

      • KCI등재

        현대패션에 나타난 바디캐스팅 디자인 연구

        박옥미(Ok Mi Pak),이승옥(Seung Ok Lee) 한국디자인문화학회 2013 한국디자인문화학회지 Vol.19 No.2

        현대패션에서 소재는 유행과 소비를 선도하게 되기도 하고, 디자인의 영감을 불러일으키는 요소로서 소재 표면의 변화로 다양한 재질을 표현함으로써 차별화, 고급화, 상징화되고 있다. 본 연구의 목적은 현대패션에서 나타난 바디캐스팅 디자인의 흐름을 분석하고, 몸(body)을 오브제로 제작한 바디캐스팅 디자인이현대패션이 추구하는 개성과 일품 디자인으로서의 패션 스타일링에 대한 적용 가능성을 살펴보는 것이다. 연구방법으로 오브제의 일반적 개념과 패션 오브제와 몸의 표현에 관한 이론적 고찰은 선행연구와 관련문헌 등을 통하여 연구하였고, 현대패션에 나타난 바디캐스팅 디자인 연구는 인터넷 사이트, 패션 전문지등의 사진을 중심으로 분석하였다. 연구범위는 패션에 표현된 몸을 독립적인 ‘바디스 오브제’로 한정하였고, 선행연구에 나타나 있는 20세기 이후 해외디자이너 작품을 중심으로 연구하였다. 그 결과 현대의 많은 디자이너들은 갑옷과 코르셋이 결합한 것으로 보이는 디자인으로 몸통 전체를 강조하며, 현대패션에 나타난 바디캐스팅 디자인은 패션 오브제의 조형성과 창조적 이미지 표현으로 나타나고 있음을 알 수 있었다. 패션 스타일링에의 적용가능성은 디자인을 계획 할 때 인체의 움직임 등을 고려하면 단점을 보완하며 스타일링이 가능하고 독특한 미를 표현할 수 있다. 바디캐스팅 디자인을 활용한 패션이 어떤 경우에나 활용될 수 있는 것은 아니지만 제한된 조건에서는 활용될 수 있고, 색다른 효과를 낼 수 있다. 바디캐스팅 디자인은 소재에 따라서 콜라주, 섬세한 엠보싱, 페이퍼 캐스팅 기법을 적용하기가 비교적 용이하므로, 앞으로 여러 소재의 장단점을 고려하여 다양한 조형방법으로 오브제를 활용한 의상뿐만이 아닌 액세서리와 문화상품 분야에서도 디자인 개발이 가능할 것이다. 본 연구를 통하여 현재 예술과 패션의 경계가 모호한 패션 경향을 반영하여 장식 조형물의 일부분으로 패션 코디네이션이 가능한 패션 오브제 디자인이 다양하게 개발되어 발전하기를 기대한다. The materials in modern fashion lead the trend and the consumption, and express various changes on materials to be differentiated, gentrified and symbolized. The purpose of this study is to analyze the trend of body casting design in modern fashion and to investigate the characteristics of using bodies as objects and the possibilities of fashion styling application as a one-style design. Literatures and previous studies were reviewed for the generalized concepts of objects, fashion objects and body expression. For up-to-date body casting design studies, internet sites and fashion magazines were used for analyses. The study was limited to independent body`s objects expressed in fashion, and focused on works of international designers since 20th century. Most of designers highlighted the entire body by combination of a armor and a corset and showed formative and creative images. The possibilities of application to fashion styling were implied by supplementing weak points by considering moves of body at the planning stage of designs, and expressing uniqueness. It is not necessarily true to fit body casting designs for all, but it could be used with limited conditions and producing very unique effects. Collage, sophisticated embossing and paper casting methods are easily applied to body casting designs depending on materials. Body casting designs could be used for formative methods not only costumes but also accessories and cultural products. It is expected to develop the various fashion object designs as a part of decorative formations using fashion coordination reflected by modern fashion trend in-between current art and fashion.

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