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      • KCI등재

        망막모세혈관종 환자에서 발생한 전층황반원공 1예

        이승범,김규섭,이원기,Seung Bum Lee,MD,Kyu Seop Kim,MD,Won Ki Lee,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.8

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Purpose: We report a case of a full-thickness macular hole treated in a female adult with bilateral retinal capillary hemangiomas. Case summary: A 20-year-old woman with bilateral retinal capilliary hemangiomas presented with blurred vision in her right eye. A thin epiretinal membrane and impending macular hole were found that did not appear to be related with a 2-disc-diameter-sized retinal angioma, telangiectactic vessels, and hard exudates in the lower retinal area of her right eye. Four months later, optical coherence tomography revealed a full-thickness macular hole in her right eye. A vitrectomy was performed, and the full-thickness macular hole was completely resolved. J Korean Ophthalmol Soc 2012;53(8):1177-1180

      • KCI등재

        다양한 골 이식재의 임상 효과에 대한 고찰

        이승범,연제영,채경준,정의원,김창성,이용근,조규성,채중규,김종관,최성호,Lee, Seung-Bum,Yon, Je-Young,Chae, Gyung-Joon,Jung, Ui-Won,Kim, Chang-Sung,Lee, Yong-Geun,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.4

        Purpose: Various bone graft materials are being used for periodontal tissue regeneration. Th materials are being developed continuously for ideal clinical effects. Therefore, it is necessary to identify the clinical characteristics of each bone graft material through comparing the various bone graft materials statistically and in doing so, proposing a more efficient bone graft material. In this study, the following results were attained through comparing the clinical effects among the bone graft materials, using the statistical method based on the clinical studies published at the department of periodontology of Yonsei hospital. Materials and Method: 6 selected studies of department of Periodontology at Yonsei University Hospital were based on clinical study of bone grafting in intrabony defects. It was compared the clinical parameters among the 6 clinical studies, using the statistical META analysis. Result: When comparing the probing depth reduction, there was a relatively great amount of decease when using the xenograft, Anorganic Bovine Derived Hydroxapatite Bone Matrix/Cell Binding Peptide(ABM/P-15: PepGen $P-15^{(R)}$) and the autogenous bone and absorbable membrane, d, 1-alctide/glycolide copolymer(GC: $Biomesh^{(R)}$). The allogfrafts showed a relatively low decrease in the probing depth and clinical attachment change. It also showed a slight decrease in the bone probing depth. The allografts showed various results according to different bone graft materials. When comparing the ABM/P-15 and bovine bone $powder(BBP^{(R)})$, ABM/P-15 showed a relatively high clinical attachment level and the bovine bone powder showed a relatively high clinical attachment level. The probing depth change and gingival recession change showed a lower value than the mean value between the two bone graft materials. The synthetic bone showed a relatively high decrease in clinical attachment level and periodontal probing depth change. There was a relatively larger amount of gingival recession when using Bioactive Glass(BG) but a relatively low bone regeneration effect was seen. Conclusion: Good restorative results of the periodontal tissue can be attained by applying the various bone graft materials being used today after identifying the accurate clinical effects.

      • 진행성 위암에서 종양 연관성 대식세포, 비만세포, 가지세포의 침윤과 임상-병리학적 인자와의 연관성

        이승범,지경천,Lee, Seung-Bum,Chi, Kyong-Chon 대한위암학회 2005 대한위암학회지 Vol.5 No.3

        목적: 신생혈관형성은 암의 증식, 침습, 전이에 있어 중요한 과정이며 위선암에서 대식세포, 비만세포는 혈관내피세포성장인자를 통한 신생혈관형성 작용을 보이고 가지세포는 혈관내피세포성장인자에 의해 기능이 억제된다. 이들 세포의 조직 침습이 조직병리 및 임상예후와 어떤 상관관계를 가지는지 알아보고자 한다. 대상 및 방법: 1999년 1월부터 2002년 12월까지 진행성 위암으로 위절제술을 받은 환자 중 79명을 대상으로 하여 파라핀 포매 조직을 이용하여 대식세포, 비만세포, 가지세포 및 미세혈관에 대한 면역조직화학 염색을 실시하고, 이들의 발현과 임상병기 및 생존율에 대한 분석을 실시하였다. 결과: 대식세포의 수는 분화도가 낮을수록, 조직침습이 깊을수록, 림프절전이가 많을수록 유의하게 감소하였으나(P<0.05), 미세혈관 밀도 및 생존기간의 차이는 보이지 않았다. 비만세포와 가지세포의 침윤정도는 조직병리 및 생존율과의 연관성을 보이지 않았다. 결론: 종양연관성 대식세포가 위암환자에 있어 예후인자로 가치를 가질 수 있을 것 인지와 대식세포의 침습부위에 따른 임상적 관련성에 대해 좀 더 세부적인 연구가 필요할 것으로 사료된다. Purpose: Angiogenesis has a critical role in tumor proliferation, invasion, and metastasis. In gastric cancer, tumor-associated macrophages and mast cells produce angiogenic factors such as VEGF, that inhibit the functional maturation of dendritic cells. The aim of this study is to identify tumor-associated macrophages, mast cells, dendritic cell infiltrations, and microvessel densities (MVD) to investigate the relationship between them and the prognosis for gastric-cancer patients. Materials and Methods: The subjects were 79 patients selected from those who had undergone a curative gastric resection for stomach cancer. With them, Immune-histochemical staining was done using CD34 for the MVD, CD68 antigen for macrophages, and S-100 protein for dendritic cells, and toluidine blue staining was done for mast cells. Results: Macrophage infiltration showed a statistically significant positive correlation with histologic differentiation and a negative correlation with invasion depth, nodal metastasis, and stage. S-100 (+) dendritic cells and mast cells had no significant correlations with histologic differentiation, invasion depth, nodal metastasis, distant metastasis, stage, and MVD. As survival, no statistically significant differences were seen between the variables. Conclusion: Tumor-associated macrophages should be evaluated as possible prognostic markers in gastric-cancer patients.

      • KCI등재
      • KCI등재후보

        백내장수술 후 발생한 안내염환자에서 최종시력과 연관된 여러 인자

        이승범,한정원,정성근,백남호.Seung-Bum Lee. M.D.. Jung-Won Han. M.D.. Sung-Kun Chung. M.D.. Nam-Ho Baek. M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.10

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Purpose: The most serious complication related to cataract surgery is endophthalmitis. Although its incidence is decreasing, it remains the great threat to the outcome of visual acuity in patients who received cataract surgery. Methods: Retrospective analysis was performed on 18 patients who were diagnosed with endophthalmitis. The following factors were investigated: method of cataract extraction, performance of anterior vitrectomy, presence of posterior capsule rupture, results of bacterial culture, existence of systemic disease, and the duration of time from initial cataract surgery to diagnosis of endophthalmitis and then to subsequent posterior vitrectomy. In addition, the differences in final visual acuity due to variations in these factors were analyzed. Results: Patients who were diagnosed with endophthalmitis and had been commenced on systemic antibiotics within a week of the cataract operation, showed better outcomes in final visual acuity (P=0.043). Conclusion: Occurrence of endophthalmitis and subsequent usage of systemic antibiotics within a one-week time frame of cataract surgery, led to statistically significant improvement in final visual acuity compared to cases in which these events occurred one week later.

      • KCI등재후보

        라식 수술시 미세각막절삭기의 유용성과 안전성

        이승범,김진형,주천기,Seung-Bum Lee,Jin-Hyoung Kim,Choun-Ki Joo 대한안과학회 2005 대한안과학회지 Vol.46 No.10

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Purpose: To evaluate the reproducibility of the flap thickness in LASIK using Moria M2 microkeratome and to examine the safety and the complication rate intraoperatively and postoperatively. Methods: 92-Ninety-two consecutive eyes of 50 patients that received LASIK using the Moria M2 microkeratome were reviewed. The mean of the predictable corneal flap thickness was compared with the mean of the created corneal flap thickness, and intraoperative and postoperative complication and safety were evaluated. Results: The average corneal flap thicknesses were 140±15.16 μm with 130 μm head and 108.01±16.72 μm with 110 μm head. There was no statistically significant correlation between the predictable corneal flap thickness and the created corneal flap thickness with the 130 μm head (p=0.001, one-sample t-test), but there was a stastistically significant correlation with the 110 μm head (p=0.573, one-sample t-test). Conclusions: The M2 Moria microkeratome created a desirable thickness with the 110 μm head, and we can expect postoperative stability of the remaining corneal thickness. The complication rate both intraoperatively and postoperatively was very low.

      • KCI등재

        치조골 결손부 치료시 calcium carbonate와 calcium sulfate 혼합물의 임상적 효과

        이승범,채경준,정의원,김창성,최성호,조규성,김종관,채중규,Lee, Seung-Bum,Chae, Gyung-Jun,Jung, Ui-Won,Kim, Chang-Sung,Choi, Seong-Ho,Cho, Kyoo-Sung,Kim, Chong-Kwan,Chai, Jung-Kyu 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.2

        Purpose: If bone grafts and guided tissue regeneration are effective individually in treating osseous defects, then the questionis, what would happen when they are combined. Bone grafts using Calcium Carbonate(Biocoral) and Guided Tissue Regeneration using Calcium Sulfate(CALMATRIX) will maximize their advantages and show the best clinical results in intrabony defects. This study was to compare the effects of a combination of CS and CC with control treated only with modified widman flap in a periodontal repair of intrabony defects. Materials and Methods: 30 patients with chronic periodontitis were used in this study. 10 patients were treated with a combination of CS and CC as the experimental group II and another 10 patients were treated with CC as the experimental group I, and the remaining 10 patients, the control group were treated only with modified widman flap. Clinical parameters including probing depth, gingival recession, bone probing depth and loss of attachment were recorded 6 months later. Results: The probing depth changes were $3.30{\pm}1.34\;mm$ in the control group, $4.2{\pm}1.55\;mm$ in the experimental group I(CC) and $5.00{\pm}1.33\;mm$ in the experimental group II(CS+CC). They all showed a significant decrease 6 months after surgery(p<0.01). There was a significant difference(p<0.05) between the control and experimental group. However there were no significant difference(p<0.05) between the experimental group I and II. The gingival recession changes w $-1.30{\pm}1.25\;mm$ in the control group, This is a significant difference(p<0.01). However, there was a $-0.50{\pm}0.53\;mm$ change in the experimental group I(CC) and $-0.60{\pm}0.97\;mm$ in the experimental group II(CS+CC). In addition, in terms of gingival recession, there was a no significance difference(p<0.05) among the groups. The clinical attachment level changes were $2.00{\pm}1.33\;mm$ in the control group, $3.60{\pm}1.58\;mm$ in the experimental group I(CC) and $4.40{\pm}1.17\;mm$ in the experimental group II(CS+CC). They all showed a significant decrease 6 months after surgery(p<0.01). There was a significant difference(p<0.05) between the control and experimental group. However there was a no significance difference(p<0.05) between the experimental group I and II. The bone probing depth changes were $0.60{\pm}0.52\;mm$ in the control group, $3.20{\pm}1.48\;mm$ in the experimental group I(CC) and $4.60{\pm}1.43\;mm$ in the experimental group II(CS+CC). All of them showed a significant decrease 6 months after surgery(p<0.01), there was a significance difference(p<0.05) among the groups. Conclusion: Treatment using a combination of CS and CC have a potential to improve periodontal parameters in intrabony defects and More efficient clinical results can be expected in intrabony defects less than 2 walls grafted with CS and CC.

      • KCI등재후보

        건강교육과 체육 특기·적성활동이 비만아동의 건강상태, 체지방율 및 혈중지질성분에 미치는 영향

        이승범(Seung-Bum Lee) 한국코칭능력개발원 2006 코칭능력개발지 Vol.8 No.1

        본 연구는 비만 아동들에게 10주간의 건강교육과 체육 특기·적성 활동을 통하여 건강상태, 체지방율 및 혈중 지질성분을 분석하여 그 차이를 검증하는 것이 목적이다. 연구대상자로 체지방율이 25%이상인 남자 초등학생 총 24명을 대상으로, 그룹Ⅰ은 건강교육 적용과 주당 1-2회 체육 특기·적성 활동에 참여한 8명이고, 그룹Ⅱ는 건강교육 적용과 주당 3-4회 체육 특기·적성 활동에 참여한 8명이며, 그룹Ⅲ는 건강교육에 참여하지 않고, 체육 특기·적성 활동에 전혀 참여하지 않은 8명으로 구분하였다. 자료처리는 SPSS Windows 12.0통계 프로그램을 이용하여 반복측정에 의한 이원 변량분석으로 처리하였다. 연구결과로 첫째, 신체적 기능과 신체적 역할 제한의 항목에서 그룹Ⅰ과 그룹Ⅱ가 증가하였으나 그룹Ⅲ는 별 차이를 보이지 않았다. 둘째, 사회적 기능과 감정적 역할제한, 정신건강의 항목에서 그룹Ⅰ, 그룹Ⅱ, 그룹Ⅲ 모두 유의한 차이를 보이지 않았다. 셋째, 체지방율에서는 그룹Ⅱ에서만 감소하였으나 그룹Ⅰ, 그룹Ⅲ는 별 차이를 보이지 않았다. 넷째, 혈중 지질성분에서는 총 콜레스테롤, 중성지방은 그룹Ⅰ, 그룹Ⅱ에서 감소를 보였으나, 그룹Ⅲ에서는 별 차이를 보이지 않았다. HDL-콜레스테롤과 LDL-콜레스테롤의 항목에서는 그룹Ⅰ, 그룹Ⅱ, 그룹Ⅲ 모두에서 유의한 차이를 보이지 않았다. 이상에서 보면 건강교육 및 체육 특기·적성 활동은 초등학생들의 신체건강 및 비만예방에 도움을 주는 것으로 나타났다. 이러한 교육활동이 모든 학교에서 자리 잡을 수 있도록 행정적, 제도적 뒷받침이 요구되며, 이를 바탕으로 체육 특기·적성 활동을 보다 활성화시켜야 할 것으로 판단된다. The purpose of this study is to analyze how health education, athletic educational program related to the talent and aptitude undertaken for 10 weeks influences on the health a state, body fat(%) and blood lipid component of obesity student. The subject were randomly assigned to one of three groups(two experimental groups and one control). Each group ended up with 8 subjects. The measurement items were physical function, role limitation-physical, social function, role limitation-emotion, mental health, body fat(%), total cholesterol, triglyceride, LDL-Cholesterol and HDL-Cholesterol. It were analyzed by repeated two-way ANOVAs. The results obtained from this study were as follows; 1. The item of physical function and role limitation-physical, group Ⅰ and Ⅱ were increased but group Ⅲ was not significant. 2. The item of social function, role limitation-emotion, mental health group Ⅰ, Ⅱ, Ⅲ all were not significant. 3. The item of body fat(%), group Ⅱ was decreased but group Ⅰ, Ⅲ were not significant. 4. The item of total cholesterol, triglyceride, group Ⅰ, Ⅱ were decreased, but group Ⅲ was not significant. 5. The item of LDL-Cholesterol, HDL-Cholesterol, group Ⅰ, Ⅱ, Ⅲ all were not significant.

      • KCI등재

        인구통계학적 요인 및 여가스포츠 참여에 따른 고령자의 삶의 질에 관한 연구

        이승범(Lee Seung-Bum),권문호(Kwon Mun-Ho) 한국관광레저학회 2011 관광레저연구 Vol.23 No.6

        The purpose of this study is to provide a positive data to examine the relations among demographic factor, leisure sports and quality of life among aged women. It analyzed the difference in quality of life by the subjects’ demographic variables and quality of life between leisure sports participation group and non-participation group. Those were sampled for the study that 300 women participating in. They took part in the survey of quality of life and were tested in the physical measurement tests. For the data analysis the Windows SPSS 10.0 was used. The frequencies, t-test, pearson’s correlation, one way ANOVA were processed and Scheffe for the after-verification. Comparing leisure sports participation group with non-participation group in quality of life, dance sport and abdominal respiration class participants were higher than the non-participation in physical factors. Abdominal respiration class participants were higher than non-participation group in emotional factors. Dance sport participants were higher than non-participation group in social factors.

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