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최은경(Eun Kyung Choi),장혜숙(Hyesook Chang),서철원(Cheolwon Suh),이규형(Kyoo Hyung Lee),이정신(Jung Shin Lee),김상희(Sang Hee Kim),김명환(Myung Hwan Kim),민영열(Young Ⅱ Min),김진천(Jin Cheon Kim),이승규(Sung Gyu Lee),박건춘(Kun Choo 대한방사선종양학회 1991 Radiation Oncology Journal Vol.9 No.2
A Retrospective study to analyze the failure pattern in locally advanced stomach cancer, treated with radical surgery and post-op chemotherapy was performed. Among 107 patients who underwent radical gastrectomy in Asan Medical Center between June 1989 and August 1990. there were 20 stageⅡ(T2NO, T2N1) and 87 stageⅢ (T3N1, T3N2) and 91 patients were eligible for study. 57 patients treated with 6 cycles of postop adjuvant chemotherapy. Among 57 patients treated with postop adjuvant chemotherapy, local failure occurred in 21% and distant failure in 12%. Among 34 patients who were not treated with postop chemotherapy, local failure occurred in 24% and distant failure in 26%. Among 29 failures including 13 locoregional, 9 distant metastasis and 7 locoregional and distant metastasis, 11 cases recurred in the anastomotic site, 3 in the gastric bed, 7 in the regional lymph nodes and peritoneal seeding occurred in 6 cases. The true incidences of gastric bed, nodal and peritoneal failures may be higher in the longer follow-up or reoperative or autopsy series. Our data sugest that postop chemocherapy is beneficial by reducing distant failure rate. Our data suggest that postop chemocherapy is beneficial by reducing distant failure rate. Postop adjuvant locoregional radiotherapy in addition to the systemic adjuvant therapy may reduce the local failure rate and potentially benefit in at least 20% of patients who developed the local failure only. 수수로가 항암요법만으로 치료한 국소 진행된 위암환자에서 치료실패의 양상을 분석해봄으로써 수술후 방사선치료의 가능성을 알아보기 위하여 1989년 6월부터 1990년 8월까지 치료받은 107명의 환자를 대상으로 후향적 분석을 시행하였다. 제2기 (T₃N₁, T₃N₂(환자는 87명이었다 16명은 수술후 추적이 어려워 91명에 대한 분석을 시행하였다. 모든 환자는 근치적 절제술을 시행받았고 이중 57명은 수술후 항암요법을 시행하고 24명은 계속적 추적 관찰만을 하였다. 국소재발율은 항암요법 시행군에서 321%, 추적관찰군에서 24%로 차이가 없었고 원격전이는 항암요법 시행군에서는 12% 추적관찰군에서는 26%로 항앙요법 시행군에서 원격 전이가 적어지는 것을 관찰할 수 있었다. 국소 재발환자의 52%는 anastomosis site에서 재발하였고 원격 전이시 가장 많이 침범되는 장기는 간이었다. 아직 추적 관찰 기간이 짧으나 수술후 방사선 치료가 최소한 20%이상의 환자에서 도움이 될것으로 생각된다.
만성신부전과 B 형 간염에 의한 간경화가 동반되었던 혼자에서의 간 - 신장 동시 이식 2 예
김유미(Yu Mi Kim),이윤정(Yun Jeong Lee),이준승(Joon Seung Lee),장상필(Sang Pil Chang),박종하(Jong Ha Park),김은경(Eun Kyung Kim),정성희(Sung Hee Jung),이영상(Yung Sang Lee),박수길(Su Kil Park),한덕종(Duck Jong Han),이승규(Seung Gyu L 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.1
We here report two cases of combined liver-kidney transplantation in patients with both end stage renal disease and hepatitis B related liver cirrhosis. The first case was a 55-year-old man with hepatitis B related liver cirrhosis and chronic renal failure, who received cadaveric liver and kidney transplantation. Immunosuppressants were cyclosporine, prednisolone, and mycophenolate mofetil. Clinical course was uneventful except for hemolytic anemia due to alloimmunization that occurs after ABO- mismatched solid organ transplantation. Hemoglobin level became stable after plasmapheresis. His renal and hepatic function is maintained up to the present time. The second case was a 42-year-old rnan with nephrotic syndrome and liver cirrhosis. The patient underwent living related-combined liver-kidney tran- splantation. Donors were his son and brother. Blood type of the patient and donors were identical and the result of HLA crossmatch was negative. On the 14th postoperative day, stenosis at anastomotic site of hepatic artery was detected. After balloon angioplasty hepatic function was normalized. At 8 months after the transplantation, the patient is stable without adverse events.
최은경,장혜숙,서처원,이규형,이정신,김상희,김명환,민영열,김진천,이승규,박건춘,Choi, Eun-Kyung,Chang, Hye-Sook,Suh, Cheol-Won,Lee, Kyoo-Hyung,Lee, Jung-Shin,Kim, Sang-Hee,Kim, Hae-Ryun,Kim, Myung-Hwan,Min-Young-Il,Kim, Jin-Cheon,Lee, S The Korean Society for Radiation Oncology 1991 Radiation Oncology Journal Vol.9 No.2
수수로가 항암요법만으로 치료한 국소 진행된 위암환자에서 치료실패의 양상을 분석해봄으로써 수술후 방사선치료의 가능성을 알아보기 위하여 1989년 6월부터 1990년 8월까지 치료받은 107명의 환자를 대상으로 후향적 분석을 시행하였다. 제2기 ($T_2N_1,\;T_3N_0$)환자는 20이었으며 제3기 ($T_3N_1,\;T_3N_2$(환자는 87명이었다 16명은 수술후 추적이 어려워 91명에 대한 분석을 시행하였다. 모든 환자는 근치적 절제술을 시행받았고 이중 57명은 수술후 항암요법을 시행하고 24명은 계속적 추적 관찰만을 하였다. 국소재발율은 항암 요법 시행군에서는 $321\%$, 추적관찰군에서는 $24\%$로 차이가 없었고 원격전이는 항암요법 시행군에서는 $12\%$ 추적관찰군에서는 $26\%$로 항앙요법 시행군에서 원격 전이가 적어지는 것을 관찰할 수 있었다. 국소 재발환자의 $52\%$는 anastomosis site에서 재발하였고 원격 전이시 가장 많이 침범되는 장기는 간이었다. 아직 추적 관찰 기간이 짧으나 수술후 방사선 치료가 최소한 $20\%$이상의 환자에서 도움이 될것으로 생각된다. A Retrospective study to analyze the failure pattern in locally advanced stomach cancer, treated with radical surgery and post-op chemotherapy was perfomed. Among 107 patients who underwent radical gastrectomy in Asan Medical Center between June 1989 and August 1990. there were 20 stage II(T2NO, T2N1) and 87 stage III(T3N1, T3N2) and 91 patients were eligible for study. 57 patients treated with 6 cycles of postop adjuvant chemotherapy. Among 57 patients treated with postop adjuvant chemotherapy, local failure occurred in $21\%$ and distant failure in $12\%$. Among 34 patients who were not treated with postop chemotherapy, local failure occurred in $24\%$ and distant failure in $26\%$. Among 29 failures including 13 locoregional, 9 distant metastasis and 7 locoregional and distant metastasis, 11 cases recurred in the anastomotic site, 3 in the gastric bed,7 in the regional lymph nodes and peritoneal seeding occurred in 6 cases. The true incidences of gastric bed, nodal and peritoneal failures may be higher in the longer follow-up or reoperative or autopsy series. Our data sugest that postop chemocherapy is beneficial by reducing distant failure rate. Our data suggest that postop chemocherapy is beneficial by reducing distant failure rate. Postop adjuvant locoregional radiotherapy in addition to the systemic adjuvant therapy may reduce the local failure rate and potentially benefit in at least $20\%$ of patients who developed the local failure only.
Alumina 첨가에 따르는 Hydroxyapatite의 기계적 성질
이승규,이동윤,이영섭,김창은 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.1
For the purpose of improving mechanical strength of hydroxyaptite, various amount of alumina powder were added to hydroxyaptite which were prepared by precipitation method using Ca(NO₃)₂4H₂O and (NH₄)₂HPO₄under the Ca/P mole ratio 1.67 and pH 11. Hydroxyaptite-alumina powder composite were sintered in H₂O gas atmosphere at 1150-1400℃. Adding alumina, hydroxyaptite was decomposed to β-tricalcium phosphate and co-existed with hydroxyaptite. In case of added alumina, bending strength was higher than that of hydroxyaptite. Maximum bending strength was 161MPa at 1300℃, 5.0wt% alumina. Added alumina restrained grain growth of the hydroxyaptite.
마그네슘 옥시클로라이드 시멘트에 있어서 Epoxy Emulsion의 첨가효과
권종기,민경렬,김창은,이승규 연세대학교 산업기술연구소 1993 논문집 Vol.25 No.1
The effects of the addition of epoxy emulsion to magnesium oxychloride cement on water resistance, weather resistance, abrasive resistance, heat evolution, compressive strength, and water absorption rate have been studied. When 6∼9 wt% epoxy emulsion had been added, the cement paste showed the best water resistance and weather resistance. It is ascribed to the formation of polymer film which interrupts the permeation of water. In case of adding 6 wt% epoxy emulsion, the cement paste showed good abrasive resistance and compressive strength. It is because the micropores in the hardened paste were filled with polymer. And the addition of 6∼9 wt% epoxy emulsion decreased water absorption rate by over 5 vol%. As a result, the optimum amount of addition of epoxy emulsion to magnesium oxychloride cement was 6∼9 wt%.
콘크리트 구조물의 안정성에 미치는 국내 플라이애쉬의 특성에 관한 연구
김창은,하재담,나종윤,이승규 연세대학교 산업기술연구소 1999 논문집 Vol.31 No.1
Fly ash is glassy dust collected from coal fired power plant. Recently, lots of researches for fly ash have been conducted in Korea and fly ash is a valuable material especially when it is used in high strength, high flowable, high durable concrete. But it is varied with coal source of power station, coal grinding and boiler conditions. Therefore quality control of fly ash itself to get high quality concrete is important. In this study, over 20 samples of Poryong and Samchonpo fly ashes are tested and analyzed. The physical and chemical properties of fly ash and their relationships are investigated and it can be applied to quality control of concrete.