전이성골암에 의한 통증에 대한 Salmon Calcitonin($Miacalcic^{(R)}$) 비강분무의 효능 및 안정성

이수용,전대근,이종석,김석준,홍석일,최수용,장진대,Lee, Soo-Yong,Jeon, Dae-Geun,Lee, Jong-Seok,Kim, Sug-Jun,Hong, Seok-Il,Choi, Soo-Yong,Jang, Jin-Dae 대한근골격종양학회 1996 대한골관절종양학회지 Vol.2 No.1

Metastaic bone tumors are usually accompanied with severe pain. The treatment modalities for this pain are so variable that patients are sometimes afraid of using them. Salmon calcitonin has a function to increase beta-endorphines followed by increasing the blood level of prostaglandin and thromboxan A2, which results in analgesic effect. This drug also has been known to decrease bone resorption. There were a few reports that parenteral use of salmon calcitonin decrease the pain from metastatic bone tumor. We wanted to know the effectiveness and tolerability of nasal spray of salmon calcitonin in relieving bone pain with metastatic tumor. We analyzed the effectiveness in the aspects of pain, sleep, performance status, mobility, supplementary analgesic use. The biologic effect of salmon calcitonin was analysed with CBC, Ca/P, BUN/Cr, uric acid. Simple radiography, alkaline phosphatase, osteocalcin, pyrilink-K were used as parameters for bone change. Eighteen cases of metastatic bone tumors took nasal spray of salmon calcitonin($Miacalcic^{(R)}$, 200IU/day) for 4 weeks, to relieve bone pain. With Wilcoxon Matched-Pairs Signed Ranks Test, we could find pain decreased significantly at 3 week and mobility become improved at 4 week of salmon calcitonin use. Other parameters didn't show any significant changes. We think the analgesic effect is mainly due to effect not on the local bone lesion but on the central nervous system, and that increased dose of salmon calcitonin can induce earlier and stronger analgesic effect.

골 및 연부 조직 종양에서의 미세 침 흡입 세포 검사

이수용,전대근,이종석,김석준,조경자,오형호,박민효,박현수,장진대,Lee, Soo-Yong,Jeon, Dae-Geun,Lee, Jong-Seok,Kim, Sug-Jun,Cho, Kyung-Ja,Oh, Hyung-Ho,Park, Min-Hyo,Park, Hyun-Soo,Jang, Jin-Dae 대한근골격종양학회 1996 대한골관절종양학회지 Vol.2 No.1

From January 1994 to August 1995 we performed 270 cases of fine needle aspiration cytology for bone and soft tissue lesions. Among them 137 cases were diagnosed histologically. Sixty-seven cases were benign and 70 cases were malignant. We analysed these on the aspect of sensitivity, specifity, positive predictive value, negative predictive value of the cytologic examination. Malignant cases consisted of bone tumor 29 cases; soft tissue tumor 25 cases; and metastatic tumor 16 cases. The sensitivity and specifity of the aspiration cytology for malignant tumor were 67.8% and 97%, respectively. The positive and negative predictive value of aspiration cytology were 97.4% and 72.7%, respectively. Among them 40 cases were primary bony lesions; 14 benign lesions, 26 malignamt bone tumors. Sensitivity of aspiration cytology for these primary bony lesion was 90%(18/20) and its specifity was 100%(13/13). Three cases showed atypical cells in cytology but with biopsy we could find them as one benign and two malignancies. Two cases of manignancy showed negative result in cytology; one was parosteal sarcoma of proximal femur and the other was osteosarcoma of proximal tibia which was biopsied already at other hospital. Although the overall sensitivity and specifity for malignant bone and soft tissue tumors were relatively low and not so predictable, the fine needle aspiration cytology for primary bony lesion was useful in the differential diagnosis of benign or malignancy.

융기성 피부섬유육종의 치료 및 예후

이수용,박종훈,전대근,이종석,김석준,Lee, Soo-Yong,Park, Jong-Hoon,Jeon, Dae-Geun,Lee, Jong-Seok,Kim, Sug-Jun 대한근골격종양학회 2000 대한골관절종양학회지 Vol.6 No.1

목적 : 융기성 피부섬유육종은 피부에 생기는 드문 종양으로서 부적절한 절제가 잦은 재발과 예후에 영향을 미치는 것으로 보고되고 있다. 저자들이 경험한 환자를 대상으로 치료와 예후의 관계를 연구하여 적절한 치료법을 제시하고자 하였다. 대상 및 방법 : 1990년 3월부터 본원 정형외과에서 치료한 융기성 피부섬유육종 환자중 추시 기간이 최소 12개월 이상인 14례를 대상으로 치료 방법 및 최종 추시까지의 상태를 점검하였다. 전례 모두 병리학적 진단하에 치료되었으며, 재발 후 전원된 9례를 포함한 13례에서 광범위 절제술이 시행되었다. 1례는 서혜부의 신경, 혈관이 종양과 인접하여 종양내 전절제술을 시행하였고 술후 항암요법을 추가한 경우였다. 결과 : 재발후 전원되었던 9례의 평균 재발 회수는 1.3 (1~2)회였으며, 처음 수술 후 첫번째 재발까지의 기간은 평균 11.8(2~24)개월이었다. 술후 최종 추시까지(평균 추시기간 50.8개월)에서 광범위절제술로 치료한 13례에서는 재발을 볼 수 없었으나, 병소내 전절제술과 항암제치료를 하였던 예에서는 반복된 재발을 보였고, 결국 폐전이로 사망하였다. 결론 : 융기성 피부섬유육종은 반드시 생검을 통한 확진 후 초기에 광범위 절제연 이상으로 절제를 시행하여야 할 것으로 사료된다. 재발은 최소한 2년까지의 추시가 있어야 그 여부를 알 수 있을 것으로 사료된다. Purpose : Dermatofibrosarcoma protuberans(DFSP) is a rare tumor of the skin with a strong tendency of infiltration to surrounding tissues. Inadequate surgical intervention brings about frequent recurrence and poor prognosis. We attempted to find a guideline for adequate treatment for DFSP. Materials and Methods : Fourteen cases who had been treated in our department since Mar. 1993 and followed up for more than 12 months postoperatively were reviewed. Including nine cases who were transferred from other hospital after recurrence, thirteen cases underwent wide resection. One case was treated by intralesional resection followed by chemotherapy (CYVADIC) due to neurovascular abutment to the mass in the inguinal area. Results : The nine cases who were transferred due to recurrences experienced recurrence in average 1.3(1-2) times and the average period until first local recurrence from primary operation was 11.8(2-24) months. The thirteen cases with wide surgical margin showed no recurrence at the final follow up. One case treated by intralesional resection and chemotherapy showed multiple recurrence and died of the disease due to lung metastasis. Conclusions : From these data, we could find that primary wide resection can be the way of reducing recurrence and metastasis, and the follow up period for the detection of recurrence should be at least two years.

300 keV 중성자(中性子)에 대한 방사선량(放射線量) 관계량(關係量)의 산정(算定)

이수용,Lee, Soo-Yong 대한방사선방어학회 1986 방사선방어학회지 Vol.11 No.1

ICRU 구(球)를 피사체(被射體)로 하여 300 keV 중성자(中性子)의 방사선량(放射線量) 관계량(關係量)을 평가(評價)하였다. 피사체내(被射體內)의 선량당량(線量當量) 분포(分布)를 직접(直接) 산정(算定)하기 위해 중성자(中性子)-광자(光子)-하전입자(荷電粒子) 결합수송(結合輸送)을 다룰 수 있는 몬테칼로 코드 NEDEP을 사용하였다. 계산결과(計算結果) 얻은 방사선량(放射線量) 관계량(關係量)은 다음과 같다. 심부선량당량지수(深部線量當量指數) $H_{I,d}:1.78{\times}10^{11}\;Sv-cm^2$ 표층선량당량지수(表層線量當量指數) $H_{I,s}:2.08{\times}10^{-1}\;Sv-cm^2$ 주위선량당량(周圍線量當量) $H^*(0.07):1.70{\times}10^{-11}\;Sv-cm^2$ 주위선량당량(周圍線量當量) $H^*(10):1.78{\times}10^{-11}\;Sv-cm^2$ 실효선질계수(實效線質係數) $\bar{Q}^*(10):12.4$ Dosimetric quantities for 300 keV neutrons in the ICRU standard tissue sphere were evaluated. The Monte Carlo code NEDEP which performs neutron-photon-charged particles coupled transport was used in the direct estimation of absorbed dose and dose equivalent. Some important quantities calculated are as follows; Deep dose equivalent index $H_{I,d}:1.78{\times}10^{11}\;Sv-cm^2$ Shallow dose equivalent index $H_{I,s}:2.08{\times}10^{-11}\;Sv-cm^2$ Ambient dose equivalent $H^*(0.07):1.7{\times}10^{-11}\;Sv-cm^2$ Ambient dose equivalent $H^*(10):1.78{\times}10^{-11}\;Sv-cm^2$ Effective quality factor $\bar{Q}^*(10):12.4$

원통형 굽힘을 받는 적층판의 임계좌굴 하중

이수용,Lee, Soo-Yong 항공우주시스템공학회 2007 항공우주시스템공학회지 Vol.1 No.4

This paper presents critical buckling loads of laminated composites under cylindrical bending. In-plane displacements are assumed to vary exponentially through plate thickness. The accuracy of this theory is examined for symmetric/antisymmetric cross-ply, angle-ply and unsymmetric laminates under cylindrical bending. Analytical solutions are provided to investigate the effect of transverse shear deformation on critical buckling loads of the laminated plates, and the results are compared with those obtained from the first-order shear deformation plate theory and the classical laminated plate theory.

비이온화방사선에 대한 제반 개념 양, 단위 및 용어

이수용,Lee, Soo-Yong 대한방사선방어학회 1995 방사선방어학회지 Vol.20 No.3

비이온화방사선(NIR)에 대한 방어는 증가되는 관심의 주제가 되고 있지만, 방사선의 유형이나 그 적용간의 의존되는 아주 다른 개념의 사용은 이 분야에서의 통일된 방법의 자료편집에 어려움을 주고 있다. 이 논문의 주된 목적은 비 이온화방사선 방어의 목적으로 확실하게 사용하는 개념, 양, 단위 및 전문용어를 제공하기 위해서이다. 그 외에 방사선방어의 표준과 피폭한도를 양으로 나타내는데 사용되는 특별한 개념과 주어진 양들의 체계적인 분류와 비교를 요약하고 또 논하였다. Protection against non-ionizing radiation(NIR) is the subject of an increasing interest but the use of very different concepts depending on the type of radiation or application, makes it rather difficult to compile studies and the data obtained in an uniformity in this field. The main object of the present paper is to summarizes and provide an inventory of concepts, quantities, units and terminology currently used for purposes of NIR protection. Furthermore a systematic classification and comparison of these quantities is given, and in particular the concepts used to quantify exposure limitation and radiation protection standards are summarized and discussed.

PLC를 이용한 전력감시시스템 개발에 관한 기초 연구

이수용(Lee, Soo-Yong),왕종용(Wang, Jong-Yong),오영대(Oh, Young-Dae),김찬혁(Kim, Chang-Hyeok),노대석(Rho Dae-Seok) 한국산학기술학회 2008 한국산학기술학회 학술대회 Vol.- No.-

전력 시스템은 인간이 만든 시스템 가운데 가장 크고 복잡한 시스템이다. 현대 디지털 경제 사회의 인 프라는 전력시스템을 통한 전기에너지의 공급과 기술에 기초하고 있다. 전력시스템은 대용량화, 대규모 화, 고 효율화를 위한 시설증대와 기술개발로 이루어져 있다. 사람이 직접 사고 현장을 가지 않고 컴퓨 터로 제어함으로써 사람의 번거로움을 기계가 대신해 줌으로서 사람의 생활을 보다 편리하며 효율성 측면에서도 기여함에 틀림이 없는 사실이다. 따라서 디지털 정보화 사회에서 언제 어디서나 인간과 설 비들이 컴퓨터와 통신네트워크에 의해 접속되는 유비쿼터스 화 사회의 에너지와 정보통신 인프라 역할 로 새롭게 전환 될 수 있음을 인식하는 전력감시시스템을 PLC 기술을 이용하여 저렴하게 구현하였다.

연부조직 골육종

이수용(Soo Yong Lee),장자준(Ja June Jang) 대한정형외과학회 1987 대한정형외과학회지 Vol.22 No.2

횡방향 모재균열을 갖는 복합재료 패널의 비선형 거동

이수용(Soo-Yong Lee),박정선(Jungsun Park),정의승(Eui-Seung Chung) 한국항공우주학회 1999 韓國航空宇宙學會誌 Vol.27 No.2

예수의 집단상담 기법 연구

이수용(Lee, soo-yong),조삼복(Cho, som-bok) 한국기독교상담심리학회 2005 한국기독교상담학회지 Vol.10 No.-

This study examined the Group Counseling Techniques of Jesus. First, I described Jesus as a counselor, the concept of the Group Counseling, the Group Counseling in the Old Testament, and the Group Counseling in the New Testament. Then I closely inspected the Group Counseling Techniques used by Jesus in the New Testament. I eliminated the 8cases that are a type of the Group Counseling in the New Testament. Then, I analyzed Jesus interviews from the point of view of counseling techniques. I found that Jesus usually used the counseling techniques of attending behavior, active listening, clarification, self-disclosure, empathy and confrontation. Jesus solved many people s difficulties through these techniques. Sometimes Jesus trained his disciples With small groups. In the Group Counseling he focused on here and now and also used modeling Jesus discharged all his duties very well. Through this study We found the core techniques of Jesus counseling to be attending behavior, active listening, clarification, self-disclosure, empathy and confrontation. Therefore we have to endeavor to practice these counseling techniques as an expert. Church is a kind of a group. If we can use the Group Counseling Techniques of Jesus well, it ll be helpful to the church. It is meaningful that this study examined the Group Counseling Techniques of Jesus.