街路 空間 改善方案에 關한 硏究 : 문정동 패션거리를 중심으로

이수옥 경원대학교 2000 국내석사

Direct Pattern Transfer of Meso- to Nanoscale Structures Using an Electrohydrodynamic Lithography

이수옥 성균관대학교 일반대학원 2009 국내석사

Direct write technologies are the most recent approaches to form fine patterns whose linewidths range from meso- to nanoscales. With a direct write approach, patterns or structures can be obtained directly without the use of variable fabrication processes, masks, and liquid for etching. Direct write technologies, therefore, are the low cost and environmental friendly processes. As one of the direct write technologies, electrohydrodynamic lithography (EHL) can be used to obtain meso- to nanoscale patterns onto a substrate. Electrohydrodynamic lithography makes use of an electrohydrodynamic film instability in which a thin liquid film can be destabilized by strong electric field, applied across two capacitor plates. Strong electric field can produce forces that overcome the surface tension in thin liquid films, including an instability that features a characteristic regular order. Pattern replication is also possible when a patterned substrate is used as a top capacitor plate. The advantage of using this electric field based technique is that (a) larger areas can be patterned in a parallel fashion, and (b) that a range of lateral length scales can be replicated in a single step. In this work, inorganic material such as TiO2 and ZnO based inorganic resists are employed as a dielectric thin film and various shapes and sizes including ordered array patterns at micron and nanometer scales were replicated using an electrohydrodynamic lithography. The patterned structures were then heat treated at various temperatures to yield crystalline structures. X-ray diffraction, Field emission scanning electron microscopy, Photoluminescence, and Raman spectroscopy were used for structural characterizations and for the demonstration of its functionality. This method can be extended to other functional oxide systems and has a great potential as a cost-effective and large area pattern transfer technology.

토사사면의 안정성 및 보강대책에 관한 사례연구

이수옥 조선대학교 2015 국내석사

A Case Study on the Stability and Reinforcement Method of Slope with Soil Lee, Suok Advisor : Prof. Kim, Daehyeon Department of Civil Engineering Graduate School of Chosun University In the process of development of the national land, the utilization of mountains and hills is incresed. In this case, the stability of a natural slope problem has been investigated. Recently, due to changes of the summer weather pattern, damage caused by debris flows is occurring in the mountainous area frequently. In this thesis, a case study on reinforcement for a failed cut slope is introduced. An extensive field investigations and analyses were performed and the most effective way of stabilizing the slope was suggested. When the soil-nailing is applied to the upper part of the slope, constructability, economical efficiency and stability are satisfactory, and safety factors of dry season and rainy season are satisfactory. This study could be a good example for similar situations in which a natural slope failure occurred.

구취발생에 영향을 주는 구강환경요인

이수옥 충북대학교 2015 국내박사

The purpose of this study is to perform factor analysis and correlation analysis to see the effects of oral environment factors on halitosis and also comparatively analyze the degree of halitosis before and after scaling. To attain the goal, 35 women in their 20’s who had good oral conditions and also understood the purpose of this study and method of its experiment properly were selected and participated in the experiment from March, 2014 till May, 2014. The paired t-test was employed to analyze how halitosis changed before, right after, and one hour after scaling, and to examine correlation between oral environment factors and halitosis, the researcher conducted correlation analysis and logistic regression analysis, thereby drawing the following conclusions: 1. Both in OG and EG, halitosis reduced more right after and one hour after scaling than before scaling. In OG, halitosis reduced statistically significantly right after scaling from before scaling (p=0.001), and the change of halitosis one hour after scaling from before scaling was also statistically significant(p<0.001). 2. According to correlation analysis on the tongue plaque and halitosis, OG(p<0.001) and EG(p=0.008) were both statistically significant, and Pearson’s coefficient was found to be 0.643 and 0.441. 3. Oral glucose residence time had significant correlation with OG among the types of halitosis(r=0.424, p=0.011). 4. According to the results of correlation analysis between the secretion of saliva flow and halitosis, there was inverse correlation, and both OG(p=0.004) and EG(p=0.003) were statistically significant. 5. The secretion of saliva showed statistically significant correlation with the buffer capacity of saliva(p=0.004), and also, the dental plaque index and cavities were found to be statistically significant(p=0.011). 6. According to the results of Multiple linear regression analysis on oral environment factors and halitosis, the ratio of the secretion of saliva flow and dental plaque ,tongue plaque were both statistically significant OG and EG to statistically significant at the significant level of (p<0.05). In brief, to control halitosis, it is needed to increase the secretion of saliva flow, and since there is much correlation between the tongue plaque and halitosis, it is necessary to reduce the amount of tongue plaque through tongue brushing. In addition, it will be more important than anything else to manage halitosis when oral conditions are good by eliminating dental plaque or scale through scaling.

한 대학병원 치과 이용자들의 구강보건 인식, 지식 및 행동에 관한 연구

이수옥 충남대학교 보건대학원 2005 국내석사

This study was conducted to provide basic data for social oral health and to promote oral health education through researching oral health knowledge and behavior. 183 clients over 18 years old who visited a university hospital dental clinic from June 2004 to August were surveyed by questionnaire. These followings are the result of this study. 1. 45.9 percent of the respondents visited dental clinic cause their oral pain. They accepted oral health knowledge through the mass media and oral health knowledge shows that there is meaningful level of significance between age and educational level. 2. 56.3 percent of the respondents brush their teeth three times a day on the average. The more women takes education, the more often they brush their teeth compared to men. 3. The more they take professional preventive dental care procedure, the more they know about the oral health. It shows that there is meaningful level of significance(p<.001). 4. On the self oral health evaluation, people who think that they need dental caries have more dental caries than people who think they need not. People who have never taken the professional preventive dental care have more dental caries than people who have it shows that there is meaningful level of significance. 5. As the knowledge of dental health is higher, the numbers of the treatment necessary decays are lower and the demand of periodontal treatment are lower. As a result, to improve the oral health, self management and periodic preventive treatment are necessary, to improve dental health, dental health education is very important so it should be strengthened.

임파워먼트(Empowerment)가 조직유효성에 미치는 영향 : 공정성 지각의 조절효과를 중심으로

이수옥 전북대학교 경영대학원 2007 국내석사

In today's rapidly changing business environments, where information-driven and globalization enter at once, enterprises should develop competitive power through renovation to maintain growth. To make this possible, the needs of securing talented people and applying new methods of administration has become embossed. Also, fresh changes through self-controlling acts of constituents has become a grave issue for the development of the businesses. 'Empowerment' is one of the concept which indicates self-control and creativeness as a means for modifying organizations. The purposes of this study are; First, to examining the influences of Empowerment on organizational effectiveness. second, to check whether Empowerment has a greater influence on organizational effectiveness when justice is recognized. For the purpose of this study, I investigated the existing researches mainly on formation background and concept. In explaining the process of Empowerment, I chose job satisfaction and organizational commitment of members as dependent variables to analyze relative influences between the variables. Also I have designed a study model to verify the adjusting role of justice recognition between Empowerment and organization effectiveness. In that order I set up a hypothesis and probated the overall theoretical formality. As a detailed studying method, first of all, I collected and examined materials such as thesis and journals written by many researchers around the world in several fields to design a study model and hypothesis. Through this process I arranged the preceeding studies of Empowerment and organizational effectiveness such as job satisfaction and organizational commitment. As an actual proof analysing method, I practiced frequency analysis to arrange population statistics variables, and to examine the inner consistency of questionnaires about each variables, I performed reliability investigation. Also, to inspect the propriety of each variable's construct I practiced Factor analysis. By practicing Correlation Analysis I checked the similarity between each variables. For probating the hypothesis I attempted Multiple regression to find out the influence of the moderator variable and relation between dependent and independent variables. Broad results of this study are as follows. First, I found out that Empowerment has a positive influence on job satisfaction and organizational commitment, which has coherence with the preceeding studies. So to speak Empowerment increases an individual's job satisfaction and organizational commitment which effectively influences the organization. Second, It is verified that for an enterprise's steady growth, Empowerment has a greater influence on job satisfaction and organizational commitment when justice recognition is highly understood. The purpose of this research was to show the relationship between Empowerment (preceeding variable) and organizational effectiveness (job satisfactory, organizational commitment; outcome variable) which were estimated to have direct corelation hitherto, can be fruitful to organization's steady growth when justice recognition (moderator variable) is appreciated through changing the constituents. With the study model and actual proofs which were presented with such intention I could acquire several suggestion points. To maintain an enterprise's steady growth, capital, technology, human resources and many other different factors are important. But above all human resource is the most important thing. So to speak, the continuous circulation of Empowerment among the constituents seems to be an alternative plan for a company's steady growth. To actualize it, enterprises should seek after organizational reform by presenting visions and goals to the members. 정보화와 글로벌화가 동시에 진입하는, 급격히 변화하는 오늘날의 기업 환경 속에서 기업의 지속적인 성장을 위해서는 기업의 혁신을 통한 경쟁력 또한 지속적으로 갖추어야 한다. 이를 위해서는 뛰어난 인재들의 확보와 더불어 새로운 관리방식에 대한 필요성이 부각되었고, 기업에서는 구성원의 자율적 행위를 통한 새로운 변화가 기업발전을 위한 커다란 이슈로 논의되기 시작하였다. 이러한 조직의 변화를 위한 자율과 창의를 하나의 방법으로서 제시되고 있는 개념이 임파워먼트라고 할 수 있다. 본 연구의 목적은 첫째, 임파워먼트가 조직유효성에 영향을 미치는지 살펴보고, 둘째로, 공정성을 지각했을 때 임파워먼트가 조직유효성에 더 큰 영향을 미치는가에 대해 살펴보고자 한다. 본 연구의 목적을 위하여 임파워먼트의 형성배경과 개념을 중심으로 기존의 연구를 검토하였으며, 임파워먼트의 과정을 설명하는데 있어서 조직유효성으로 구성원들의 직무만족과 조직몰입을 종속변수로 선정하여 변수간의 상대적 영향력 정도를 분석하여 보았고, 임파워먼트와 조직유효성 간의 관계에 조절변수인 공정성지각의 조절역할을 검증하기 위한 연구모형을 설계하고 가설을 수립하여 전체적인 이론적 틀을 검증하여 보았다. 세부적인 연구방법으로 우선 연구의 모형과 연구의 가설을 설계하기 위한 문헌적인 연구로 국내외의 여러 연구자들에 의해 연구된 각 분야의 논문과 학술지 등의 자료를 수집, 분석하고, 이 과정을 통해 임파워먼트의 선행연구와 조직유효성인 직무만족, 조직몰입에 관한 연구들을 정리하였다. 실증분석방법으로는 인구통계학 변수를 정리하기 위하여 빈도분석(frequency analysis)을 실시하였고, 각 변수들에 대한 설문문항의 내적 일관성을 조사하기 위하여 신뢰도 검증(reliability)을 실시하였다. 또한 각 변수들의 구성개념 타당성을 검증하기 위하여 요인분석(Factor analysis)을 실시하였으며, 각 변수들의 관계 유의성을 살펴보기 위해서 상관관계 분석(Correlation Analysis)을 하였으며, 가설검증을 위한 분석으로 독립변수와 종속변수와의 관계와 조절변수의 영향을 알아보는 다중회귀분석(Multiple regression )을 실시하였다 본 연구의 개략적인 연구결과는 다음과 같다. 첫째, 임파워먼트는 직무만족과 조직몰입에 유의한 영향을 미치는 것으로 나타났으며, 이는 선행연구들과 일관성이 있는 결과이다. 즉, 임파워먼트는 개인으로 하여금 직무만족 및 조직 몰입도를 높혀 줌으로써 조직에 유효한 영향을 미치는 것으로 나타났다 둘째, 임파워먼트가 개인의 직무만족과 조직몰입에 미치는 영향에 있어서, 조절변수인 공정성지각을 높게 인식했을 때 직무만족과 조직몰입에 더 큰 영향력을 주어 조직의 지속적인 성장에 유의한 것으로 나타났다. 본 연구는 종래 직접적인 상관관계가 있다고 판단되었던 선행변수인 임파워먼트와 결과변수인 조직유효성(직무만족, 조직몰입) 사이를 조절변수인 공정성 지각이 인식되었을 때 구성원을 변화시킴으로써, 조직의 지속적인 성장에 효과가 있음을 보여주고자 하는 것이었다. 이러한 의도에서 제시한 본 연구모형 및 그 실증분석의 결과 몇 가지 시사점을 얻을 수 있었다 기업의 지속적인 성장을 위해서는 자본, 기술, 인적 자원 등 많은 것들이 중요하지만, 그 중에서도 제일 중요한 것은 인적 자원이라고 본다. 즉, 구성원들의 끊임없는 임파워먼트의 순환이 조직의 지속적인 성장을 유지시켜 줄 대안이라고 생각되며, 이를 위해 기업들은 구성원들이 공유할 수 있는 미래의 비젼 및 목표를 제시함으로써 조직의 변화를 계속 추구하여야 할 것이라고 생각한다.

리질리언스 관점으로 본 산업유산의 문화공간 특성 연구

이수옥 국민대학교 디자인대학원 2024 국내석사

Contemporary architecture has achieved remarkable advancements in spatial composition and structural systems through technological progress and aesthetic experimentation, evolving toward an expanded social role beyond the improvement of urban landscapes and living environments. However, function-driven development logic and expansion-oriented urban strategies have caused structural side effects, such as environmental degradation, disruption of urban fabric, and social imbalance. These issues have further intensified in the 21st century in conjunction with crises including economic instability, climate change, the normalization of pandemics, and complex disasters. Within this context, the concept of resilience has emerged as a core analytical framework in the fields of urban planning and architecture. Resilience now encompasses not only the ability to recover but also the capacity of urban systems to absorb shocks and create a sustainable order through structural transformation. In particular, changes in industrial structure and population decline have led to the large-scale idling of industrial heritage sites created during the industrialization period, resulting in complex problems such as deepening spatial imbalance, disintegration of community foundations, and weakening of regional identity. Industrial heritage is no longer seen as merely obsolete physical structures but as locational assets embodying the industrial memory and historical identity of a region, with the potential to gain new social meanings and functions through cultural regeneration. The transformation of industrial heritage into cultural spaces can act as a complex urban regeneration strategy that mediates between past and present, reconstructs collective memory, restores urban identity, promotes civic participation, and facilitates organizational integration. When combined with cultural programs, industrial heritage can function as a practical foundation for enhancing community resilience, generational integration, and environmental responsibility. This study aims to systematically analyze cultural spaces based on industrial heritage from a resilience perspective and to identify their structural characteristics that contribute to urban resilience. The analytical framework is constructed around three dimensions of resilience: psychological (1Point), social (2Point), and institutional (3Point). A total of 11 case studies—five domestic and six international (three in Asia and three in Europe)—were selected for literature review and comparative analysis. The interrelationship between spatial characteristics and resilience elements was explored, and the operational structures by type were examined in a multidimensional manner. The findings indicate that industrial heritage spaces promote psychological resilience through emotional structures that induce emotional stability and empathetic experiences. They also serve as spaces that strengthen social cohesion and operational practicality through the formation of community networks and voluntary participation. Furthermore, they function as experimental platforms that accept and reinterpret institutional norms flexibly, thereby accommodating institutional resilience. In this way, industrial heritage cultural spaces can be interpreted as multi-layered resilience structures integrating emotion, function, institution, and identity, and can be defined as practical foundations for reconstructing urban identity and resilience. The integrated approach to locality and socio-cultural function offers a strategic alternative for sustainable urban recovery, expanding the conventional discourse of urban regeneration. By systematizing the resilience implementation structure of industrial heritage cultural spaces, this study proposes an analytical framework and design strategies applicable to similar future regeneration cases, thereby providing a theoretical and practical foundation for enhancing urban resilience. 현대 건축은 기술 진보와 미학적 실험을 통해 공간 구성과 구조 체계 전반에서 획기적인 진전을 이루었으며, 도시 경관 개선과 생활환경 향상을 넘어 건축의 사회적 역할을 확대하는 방향으로 진화해 왔다. 그러나 기능주의적 개발 논리와 도시 확장 중심의 전략은 자연환경의 훼손, 도시 조직의 단절, 사회적 불균형 등의 구조적 부작용을 초래하였으며 이러한 문제는 21세기 들어 경제 불안정, 기후 위기, 감염병의 상시화, 복합 재난 등의 위기 상황과 맞물리며 더욱 심화되고 있다. 이러한 배경 속에서 회복탄력성(Resilience) 개념은 도시계획 및 건축 분야에서 핵심적 분석 틀로 부상하였으며 단순한 복원 능력을 넘어 도시 시스템이 위기를 흡수하고 구조적 전환을 통해 지속가능한 질서를 창출할 수 있는 능력으로 확장되고 있다. 특히 산업구조 변화 및 인구 감소는 산업화 시기 조성된 산업유산의 대규모 유휴화를 초래하고 있으며 도시공간의 불균형 심화와 공동체 기반의 해체, 지역 정체성의 약화라는 복합적 문제로 귀결되고 있다. 산업유산은 단순히 기능을 상실한 물리적 구조물이 아니라 지역의 산업적 기억과 역사적 정체성이 응축된 장소적 자산으로 해석하며 문화적 재생을 통한 새로운 사회적 의미와 기능을 획득할 가능성을 내포하고 있다. 산업유산의 문화 공간화는 과거와 현재를 매개하고 공동체의 집합적 기억을 재구성하며 도시 정체성 회복과 시민 참여, 조직적 통합을 실현할 수 있는 복합적 도시재생 전략으로 작동할 수 있다. 문화 프로그램과 결합한 산업유산은 공동체 회복력, 세대 통합, 환경적 책무를 강화하는 실천 기반으로 기능할 수 있다. 본 연구는 산업유산 문화공간을 리질리언스 관점에서 체계적으로 분석하고 해당 공간이 도시 회복탄력성 실현에 기여하는 구조적 특성을 규명하는 데 목적을 둔다. 분석의 틀로는 리질리언스를 심리적 관점(1Point), 사회적 관점(2Point), 제도적 관점(3Point)으로 구분하여 분석의 틀을 구성하였으며 국내 사례 5개소, 해외 사례로 아시아 3개소, 유럽 3개소 등 총 11개 산업유산 문화공간인 사례를 선정하여 문헌 조사 및 비교분석을 수행하였다. 공간 특성과 리질리언스 요소 간 상호관계를 도출하고 유형별 작동 구조를 입체적으로 고찰하였다. 연구 결과 산업유산 공간은 정서적 안정감과 공감 경험을 유도하는 감성적 구조를 통해 심리적 리질리언스를 구현으로 공동체 네트워크 형성 및 자발적 참여 기반의 운영을 통해 사회적 응집력과 실천성을 강화하는 공간으로 기능한다. 또한 제도와 규범에 대한 비판적 수용과 재해석을 통해 변화에 유연하게 대응하는 구조를 갖춰 제도적 리질리언스를 수용하는 실험적 장치로 작동하는 특성을 보였다. 이처럼 산업유산 문화공간은 감성, 기능, 제도, 정체성이 통합된 다층적 리질리언스 구조로 해석으로 도시의 정체성과 회복탄력성을 재구성하는 실천적 기반으로 규정될 수 있다. 장소성과 사회문화적 기능을 복합적으로 통합하는 접근은 기존 도시재생 담론의 범주를 확장과 지속가능한 도시 회복을 위한 전략적 대안으로 실천 가능성을 제시한다. 산업유산 문화공간의 리질리언스 구현 구조를 체계화함으로써 향후 유사 공간 재생 사례에 적용 가능한 분석 틀과 설계 전략을 제공하며 도시의 회복탄력성 강화에 기여할 수 있는 이론적·실천적 기반을 제안하고자 한다.

금속하부구조물이 도재의 색조에 미치는 영향에 대한 분광측색분석

이수옥 경희대학교 대학원 2001 국내석사

Metal-ceramic restorations have been used extensively by dental clinicians for nearly 40 years. Strength an functional ability of metal-ceramic restorations are proved to be satisfying, However esthetics and biocompatibility of metal alloy which is used in metal-ceramic restoration is not ideal. Using pure gold as an alternative, have advantage of esthetics, biocompatibility over conventional metal alloy. The purpose of this study was to spectrophotometrically evaluate the difference in color of metal alloy(Au-Pt, Ni-Cr) and pure gold, and to analyze the differences. Three types of metal - base metal(Ni-Cr), high gold alloy(Au-Pt), pure gold(GES) - specimen were fabricated 1cm in diameter. Four steps were established - after finishing , after pre-coditioning, after application of first opaque porcelain(0.08mm in thickness), after application of second opaque porcelain(0.15mm in thickness)- and tested color with spectrophotometer every each steps and analyzed with CIEL*a*b* color order system. The results were as follows. ; 1. After finishing and pre-conditioning, pure gold(GES) group showed most high values in L*,a*,B*. 2. After application of first opaque porcelain(0.08mm in thickness), after application of second opaque porcelain(0.15mm in thickness), pure gold(GES) group showed the least difference in L*,a*,b* values and the lowest ΔE value(ΔE=0.63). 3. After application of first opaque porcelain and after application of second opaque porcelain differences that were significant (P < 0.05) between groups were found only in a* values. 4. Base metal alloy group showed the lowest a* value in test after application of first opaque porcelain and the highest value in test after application of first opaque porcelain

비만클리닉 외래방문자 중 폭식 및 야식을 보이는 대상자들의 특성

이수옥 연세대학교 생활환경대학원 2006 국내석사

비만 인구가 증가하면서 비만과 밀접한 관련이 있는 섭식장애에 대한 관심도 증가하고 있다. 우리나라에서는 청소년과 대학생을 대상으로 시행한 폭식장애 관련 연구는 있으나 성인을 대상으로 한 연구는 거의 없는 실정이다.본 연구는 비만클리닉 외래방문자 중 폭식 및 야식을 보이는 대상자들의 인구사회학적 특성을 파악하고 관련요인이 무엇인지 분석하고자 하였다. 이를 위해 516명(남성 141명, 여성 375명)을 대상으로 신체계측 및 설문조사를 시행하였다.폭식은 남성 14.9%, 여성 13.9%, 야식은 남성 41.1%, 여성 39.7%로 나타났고, 폭식증은 여성 4.8%의 빈도를 보였다. 신경성 대식증은 전체 여성의 2.4%, 야간식사증후군 역시 여성에서만 1.4% 관찰되었다. 폭식군과 비(非)폭식군을 비교해본 결과 폭식군 41.1%에서 BMI 30kg/m2이상이 비폭식군 21.0%에 비해 높았고(P<0.01), 야식군과 비(非)야식군을 비교해본 결과 흡연자(P<0.01) 및 음주자(P<0.01)가 야식군에서 많았다. 교차비(odds ratio)를 보았을 때, 폭식의 경우 비만이 심하고, 가계수입이 낮은 군에서 높게 나왔으며, 야식의 경우 흡연자와 음주자, 고졸 이하 학력자에서 높았다.폭식군들의 식사 패턴은 과식, 1회 섭취량 과다, 빠른 식사속도가 특징적인 반면, 야식군들의 식사 패턴은 아침 결식, 불규칙한 식사시간, 과식, 빠른 식사속도, 잦은 외식이 특징적이었다.간이 식생활 진단표를 이용한 분석 결과 폭식군에서 아이스크림, 탄산음료를 비폭식군에 비해 더 많이 섭취했고, 야식군에서는 3개 항목을 제외한 모든 항목에서 비야식군과 통계적으로 의미있는 차이를 보였다(P<0.01). 단백질 섭취가 적고, 튀김이나 지방이 많은 육류를 더 많이 섭취하고, 짜게 먹는 습관, 식사의 불규칙, 아이스크림, 탄산음료 등 간식 섭취에서 전반적인 식습관이 좋지 않은 것으로 나타나 전반에 걸쳐 개선이 필요한 것으로 나타났다. 폭식이나 야식을 보이는 대상자들의 특성을 식습관 교정 및 상담 프로그램을 개발하는 데 활용한다면 비만치료에도 보다 나은 결과를 얻을 수 있을 것으로 사료된다. Since obese population increased, the interest of eating disorder, closely related with obesity has also increased.Especially, binge eating or night eating is the main symptom of binge eating disorder, bulimia nervosa or night eating syndrome, which can be causative of obesity in itself. In Korea, some studies regarding the binge eating disorder for juveniles and college students have been reported, but there are few studies for adult population.Therefore, this study was to investigate the demographic and social characteristics of individuals with binge eating or night eating in those who visited an obesity clinic and to analyze the related factors.The frequency of binge eating was 14.9% for man and 13.9% for women, and the frequency of night eating 41.1% and 39.7%, respectively. There was no statistical difference between men and women. Among the women subjects, the prevalence of binge eating disorder was 4.8% and the prevalence of bulimia nervosa was 2.4%. The prevalence of night eating syndrome corresponding to 5 diagnostic criteria was 1.4%. Compared with non-binge eating group, binge eating group had higher proportion of subjects belong to class Ⅱ obesity and subjects with low economic status. The proportions of smokers, drinkers, and people with low educational background were higher in night eating group compared with non-night eating.The characteristics of daily pattern of binge eating subjects were over eating, large portion size and fast eating speed. The characteristics of daily pattern of night eating subjects were skipping breakfast, irregular meal time, large portion size, fast eating speed and frequent dining out. Night eaters showed significantly lower scores for their overall diet habits evaluating by MDA (mini dietary assessment index) compared with non-night eaters.If these characteristics of patients with binge eating or night eating are applied to practical management for obese patients, it can be bring better outcomes to treatment of obesity.

양적형질유전자의 연관성분석을 위한 가계자료의 정보충분성 연구

이수옥 연세대학교 대학원 2005 국내석사

We study pedigree selection to raise power and reduce time and expense in quantitative trait locus(QTL) linkage analysis. The method allocates a quantitative index of potential informativeness to each pedigree on the basis of observed trait scores and an assumed true QTL model. Therefore any sample of phenotypically screened pedigrees can be easily rank-ordered for genotyping. This index represents the weighted sum of test statistics that would be obtained given the observed trait value over all possible pedigree genotypic configurations. Each configuration is weighted by the likelihood of it occurring given the assumed true genetic model. We applied our methods to the data from a cardiovascular genome center and calculated informativeness index at every pedigree. And the pedigree that have high index of informativeness have more possibility of detection in QTL linkage analysis. 본 논문은 연관성 분석에 있어 검정력을 높이고 시간비용적인 절감을 위한 방법의 하나로 정보충분성을 이용한 가족자료 선택에 대해 연구하였다. 양적형질이 조사된 경우 가정된 모형이 실제모형을 잘 반영한다는 가정을 바탕으로 각 가계의 잠재적 정보충분성을 양적 지표로 표현하였다. 이를 통해 양적형질이 조사된 가계자료를 이용하여 정보충분성 지표를 기준으로 순위를 주어 유전자 판독시 정보력 있는 가계를 선택하는 기준이 될 수 있다. 정보충분성 지표는 양적형질이 조사된 각 가계에서 나올 수 있는 모든 가능한 유전적 구성에서 실제 유전모형이 가정되었을 때 그 유전적 구성이 일어날 확률로 가중을 주어 계산한 검정통계량의 합을 의미하게 된다. 본 방법을 이용하여 일 병원 심장혈관유전체연구센터의 실제자료에 적용하여 가계별 정보충분성 지표를 얻을 수 있었으며, 지표의 상위에 속하는 가계가 그렇지 않은 가계에 비해 연관성을 발견할 가능성이 높은 것으로 나타났다.