추출용매에 따른 진피 추출물의 항산화 활성

이성구,오성천,장재선,Lee, Sung-Gu,Oh, Sung-Cheon,Jang, Jae-Seon 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.3

본 연구에서는 진피의 활용도를 높이기 위한 연구의 일환으로 유기용매별에 따른 생리활성물질의 용출량을 측정하기 위해, 진피와 에탄올 진피 추출물을 대상으로 유기용매인 에틸 아세테이트, 아세톤, 염화 메틸렌, 메탄올을 이용하여 추출한 시료를 대상으로 총 폴리페놀 함량, 전자공여능, glutathione S-transferase(GST)의 활성 저해력을 측정한 결과는 다음과 같다. 1. 총 폴리페놀 함량은 ethyl acetate인 경우 진피는 $928.48{\pm}1.19{\mu}g\;GAE/mL$, 에탄올 추출 진피는 $664.64{\pm}0.74{\mu}g\;GAE/mL$로, acetone인 경우 진피는 $886.03{\pm}0.44{\mu}g\;GAE/mL$, 에탄올 추출 진피는 $702.67{\pm}0.85{\mu}g\;GAE/mL$로, methylene chloride인 경우 진피는 $413.08{\pm}1.39{\mu}g\;GAE/mL$, 에탄올 추출 진피는 $429.64{\pm}0.61{\mu}g\;GAE/mL$로, methanol인 경우 진피는 $12,648.60{\pm}0.56{\mu}g\;GAE/mL$, 에탄올 추출 진피는 $16,108.20{\pm}0.73{\mu}g\;GAE/mL$로 나타나, 진피나 에탄올 추출 진피는 모두 methanol로 추출한 것이 상대적으로 높게 나타났으며, 총 폴리페놀의 함량 차이는 유기용매별 통계적으로 유의한 차이가 나타났다(p<0.05). 2. 전자공여능은 ethyl acetate인 경우 진피는 62.80%, 에탄올 추출 진피는 51.49%로 나타났으며, acetone인 경우 진피는 97.43%, 에탄올 추출 진피는 63.17%로 나타났으며, methylene chloride인 경우 진피는 52.20%, 에탄올 추출 진피는 67.68%로 나타났으며, methanol인 경우 진피는 97.63%, 에탄올 추출 진피는 96.18%로 나타났다. Electron donating ability(EDA)는 유기용매 중 메탄올로 추출하였을 때가 상대적으로 가장 높게 나타났으며, 유기용매별로 통계적으로 유의한 차이가 나타났다(p<0.05). 3. Glutathione S-transferase(GST)에 대한 활성 저해능은 ethyl acetate인 경우 진피는 76.22%, 에탄올 추출 진피는 75.54%로 나타났으며, methylene chloride인 경우 진피는 31.73%, 에탄올 추출 진피는 73.53%로 나타났으며, methanol인 경우 진피는 97.48%, 에탄올 추출 진피는 48.70%로 나타났다. Glutathione S-transferase(GST)에 대한 활성 저해능은 진피인 경우 유기용매 중 메탄올로 추출하였을 때가 가장 높게 나타났고, 에탄올 추출 진피인 경우는 에탄올과 methylene chloride로 추출할 때가 높게 나타났으며, 유기용매별로 통계적으로 유의한 것으로 나타났다(p<0.05). In this study, the total polyphenol content, electron donating ability (EDA) and inhibitory activity of glutathione S-transferase (GST) of freeze-dried Citrus unshiu extracts were examined. The Citrus unshiu extracts was obtained from four solvents such as ethyl acetate, acetone, methyl chloride and methanol, to evaluate its functional properties. Total polyphenol contents were measured in the two different extracts, and the extracts were screened for their potential antioxidant activities using tests such as electron donating ability (EDA), glutathione S-transferase (GST). The total polyphenol contents of Citrus unshiu extracts were $928.48{\pm}1.19{\mu}g\;GAE/mL$ in ethyl acetate (EA), $886.03{\pm}0.44{\mu}g\;RE/mL$ in acetone (AC), $413.08{\pm}1.39{\mu}g\;GAE/mL$ in methylene chloride (MC), $12,648.60{\pm}0.56{\mu}g\;GAE/mL$ in methanol (MeOH), respectively. Also, the total polyphenol contents of EtOH Citrus unshiu extracts were $664.64{\pm}0.74{\mu}g\;GAE/mL$ in EA, $702.67{\pm}0.85{\mu}g\;RE/mL$ in AC, $429.64{\pm}0.61{\mu}g\;GAE/mL$ in MC, $16,108{\pm}0.73{\mu}g\;GAE/mL$ in MeOH, respectively. The total polyphenol contents were significantly difference (p<0.05) between the solvents. The electron donating ability of Citrus unshiu extracts were $62.80{\pm}0.36%$ in EA, $97.43{\pm}0.51%$ in AC, $52.20{\pm}0.30%$ in MC, $97.63{\pm}0.46%$ in MeOH, respectively. Also, the electron donating ability of EtOH Citrus unshiu extracts were $51.49{\pm}0.26%$ in EA, $63.17{\pm}0.31%$ in AC, $67.68{\pm}0.55%$ in MC, $96.18{\pm}0.41%$ in MA, respectively. The electron donating ability were significantly difference (p<0.05) between the solvents. The inhibitory activity of glutathione S-transferase in Citrus unshiu extracts were $76.22{\pm}0.65%$ in EA, $31.73{\pm}0.48%$ in MC, $97.48{\pm}0.56%$ in MeOH, respectively. Also, inhibitory activity of glutathione S-transferase in EtOH Citrus unshiu extracts were $75.54{\pm}0.55%$ in EA, $73.53{\pm}0.38%$ in MC, $48.70{\pm}0.46%$ in MeOH, respectively. The inhibitory activity of glutathione S-transferase were significantly difference (p<0.05) between the solvents. These results indicated that the Citrus unshiu extracts is a high-valued food ingredient and the extraction with methanol will be useful as a nutritional source with natural antioxidant activities. Considering high consumer demand beneficial health effects, Citrus unshiu extracts can be utilized to develop functional food health- promoting and natural antioxidant agents.

자석 Skew 착자를 통한 외전형 BLDC 모터의 성능개선설계

이성구(Sung-Gu Lee),한진우(Jin-Woo Han),김덕진(Deok-Jin Kim),김광수(Kwang-Soo Kim),김영관(Young-Kwan Kim) 대한전기학회 2013 대한전기학회 학술대회 논문집 Vol.2013 No.7

자속집중형 BLDC를 이용한 원가절감 설계에 관한 연구

이성구(Sung Gu Lee),정재웅(Jae Woong Jung),정수권(Soo Kwon Jung),남용우(Yong Woo Nam),김영관(Young Kwan Kim) 대한전기학회 2015 대한전기학회 학술대회 논문집 Vol.2015 No.7

고속 추진 시스템용 LSM 설계

이성구(Sung Gu Lee),원성홍(Sung Hong Won),김태형(Tae Heoung Kim),이형우(Hyung Woo Lee),권삼영(Samyoung Kwon),이주(Ju Lee) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7

This paper provides the design of propulsion system for the catenary-pantograph run tester. Permanent magnet linear synchronous motor design suitable for an high-speed ground transportation system which need a big acceleration force. The propulsion system of the catenary-pantograph run tester need high speed and big acceleration.

SRM의 DC linke 전압리플을 고려한 단일 펄스 구동 방식의 특성 해석

李聖九(Sung-Gu Lee),鄭大成(Dae-Sung Jung),李柱(Ju Lee) 대한전기학회 2008 전기학회논문지 Vol.57 No.11

This paper deals the characteristic analysis of Switched Reluctance Motor(SRM) driven by single-pulse mode considering dc link voltage ripple. Two dimensional time-stepped Finite Element Method(FEM) is used to analyze the characteristic of SRM driven by single-pulse mode with dc link voltage ripple. The analysis results is verified by experimental test.

한국형 합동전술데이터링크 구축을 위한 관한 전파환경 채널 모델링

이성구 ( Sung-gu Lee ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.2

It has to secure the reliability for the propagation performance in the physical layer of the products for comprising system in order to satisfy the service quality. The radiowave environment under the actual service circumstance is measured. By using the channel model which models and which it obtains, the performance about the access device tries to be tested under the laboratory environment and there is the object of channel modeling.

유한 요소법과 실험계획법을 병행 사용한 고정밀 자기 부상 시스템의 최적 설계

이성구(Sung Gu LEE),원성홍(Sung Hong Won),이형우(Hyung Woo LEE),이주(Ju Lee) 대한전기학회 2005 대한전기학회 학술대회 논문집 Vol.2005 No.7

사학부(史學部) : 황제전승(黃帝傳承)의 재검토

이성구 ( Sung Gu Lee ) 한국중국학회 2010 중국학보 Vol.62 No.-

本文首先對繼往的"黃帝傳承"的疑古式硏究做批判性的探討, 然後整理出目前中國國內的有關"曆史上的黃帝"的硏究現況和課題, 最後通過對"黃帝原型"的神話學的考察, 試圖摸索出一條新的出路, 從而克服疑古的、曆史的硏究方法上所存在的局限性。顧힐剛等疑古學派認爲, 黃帝原本是一個神話人物, 後來隨著戰國時代的人文主義運動, 逐漸轉化成爲古聖王, 這就是所謂``神話的曆史化``理論。特別是顧힐剛的關於"戰國時代的黃帝崇拜源於道家和陰陽家的自我吹噓"這一主張, 旣然諸子利用了"黃帝權威", 那마正說明"黃帝崇拜"已經得到了普及, 而這又和顧힐剛的主張自相矛盾, 說明這一主張是缺乏說服力的。但是這種"黃帝或黃帝傳說是在戰國時代的政治思想的需求下捏造的産物"的觀點, 在繼承發揚了顧힐剛的疑古學立場的日本仍然是主流認識。特別是大多數的日本學者都同意"黃帝是戰國時代根據五行說創造出的架空的存在"這一論調, 其主要根據就是黃帝的``黃``字相當於五行說的中央和土。但如果從``黃``字的語源是"璜形玉佩"這一角度來看的話, 黃帝是五行說産物的通說就應該廢棄掉。此外, 黃帝傳承的"齊國起源說"已經被證明是虛構的, 而且也確認了有關黃帝傳說的發祥地的多種解釋, 以及黃帝傳說的"西方傳來說"等都沒有確鑿的根據。批判地探討黃帝傳承的疑古的立場, 發現大部分都把黃帝的興起歸結於諸子思想運動的結果, 認爲黃帝傳說是極少數識字階層的專有物。但是我們應該注意到, 那些記錄黃帝傳說的道家、陰陽家、兵家、方術家等系列的先秦文獻, 都是以原始段階的神話式世界觀或者呪術的思惟作爲基礎的, 因此就可以推斷黃帝崇拜是以悠久的神話傳統爲背景的, 而且到了戰國時代, 民衆的信仰和習俗中仍然廣泛地存在黃帝崇拜。中國的曆史界和考古學界一方面批判疑古派把古史傳說逐出了曆史領域, 從而導致了上古史的長期空白, 령一方面傾全力去克服疑古學派幷致力於複原黃帝時代。他們提出所謂的二重證據法, 努力證明黃帝是一個曆史的實在, 但是目前留存的有關黃帝的文獻資料都是極度斷片的, 而且有關黃帝的地下出土資料近乎全無, 因此這就成爲了幾乎不可能完成的工作。就算黃帝是上古氏族的始祖或是英明的祖先, 但是要想通過出土古文字資料或考古學文化來接近其"實體"是近乎不可能的。首先, 用古文字資料來接近黃帝的企圖, 就如鄒衡得出的結論, 卽, 雖然黃帝族作爲周族的"著名氏族", 從先周文化就可確認其實體,但黃帝傳說的起源是흔難追溯到新石器時代的。而且卽使嘗試去將考古學和傳說結合起來, 但考古學和傳說到底是完全不同的範疇, 想要成功結合的話是흔困難的。再說這種做法也幷不是什마中國考古學的特殊附加方案, 反而是一種被普遍認爲的做學問的禁區。因此有必要結合文獻留存的有關黃帝傳承和神話思惟或是通過反映習俗的圖象資料來接近黃帝原型。本文確認的可推斷爲黃帝原型的首尾相接的人面蛇身像, 得以在石家河文化的玉器中證明, 這不能說不是中國學界所推崇的金科玉條的二重證據法的흔好的例證, 因此中國學界把這種神話學的接近方法視爲模範典範。而與此同時得出的黃帝原初的神格結果--黃帝不僅是體現了天地開闢以前的混沌和暗黑,同時也是體現以後的秩序和光明的創造主, 還起著太陽神的功能。對於黃帝的神格, 我們不能理解爲混沌和秩序的二元對立, 而應該理解爲這正是兩者的相互循環的古代中國的思惟的體現, 比如, 黃帝同時體現混沌和秩序, 以及天上界和地(下)界, 在곤和禹的身上也得到確認。黃帝生陰陽, 或水界和天上界,以及混沌和秩序互相循環的形象, 방佛太極或道的運動, 因此太極·道·太一可理解爲黃帝神話的哲學化, 特別是戰國時代的道家文獻中頻繁出現的"周而復始", 就源於表現爲環形蛇的黃帝的原型。

매입형 영구자석 전동기에서 발생하는 3차원 회전자 누설자속에 관한 연구

이성구(Sung Gu Lee),조윤현(Yun-Hyun Cho) 한국자기학회 2021 韓國磁氣學會誌 Vol.31 No.3

In the rotor of the interior permanent magnet synchronous motor (IPMSM), leakage flux that cannot link the coil of the stator among the magnetic flux generated by the permanent magnet (PM). Among the rotor leakage flux generated in the IPMSM, the 2D component passing through the rib can be considered through the 2D finite element analysis (FEA). However, in the rotor leakage flux of an IPMSM, there is a component of a 3D path that cannot be considered by a 2D FEA. This 3D rotor leakage magnetic flux is generated between the rotor core regions separated by PMs, and its path is 3D through air, which is a non-magnetic substance located at the upper and lower ends of the rotor core in the axial direction. In this study, a 3D FEA model with an axial air dummy is proposed to analyze the cause of 3D leakage magnetic flux in a IPMSM and to accurately consider it. Also, how the calculation result of the 3D leakage magnetic flux according to the height of the axial air dummy is affected was analyzed. Finally, the effect of 3D rotor leakage magnetic flux on no-load back electromotive force and cogging torque was confirmed through comparison of 2D FEA and 3D FEA of IPMSM with specific specifications.

유한요소법을 이용한 선형유도전동기의 횡방향 모서리 효과 분석

李聖九(Sung-Gu Lee),裵在男(Jae-Nam Bae),李衡雨(Hyung-Woo Lee),朴?濬(Hyun-June Park),權三榮(Sam-Young Kwon),李柱(Ju Lee) 대한전기학회 2008 전기학회논문지 Vol.57 No.12

In this paper, the construction of secondary reaction plate is analyzed by 3-D Finite Element Method (3-D FEM) to consider the influence of its variation on the transverse edge effect of LIM. The effective 3-D analysis model for considering the transverse edge effect caused by the finite widths of the primary and the secondary is proposed. The simple method measuring the transverse edge effect by using the patterns of currents induced in the secondary reaction plate is also proposed. With this effective analysis method, various models of secondary reaction plate with overhang and cap has been analyzed to consider the relationship between the construction of secondary reaction plate and the transverse edge effect of LIM.