기공에 기초한 스트레스 관리 프로그램이 산모의 정서에 미치는 영향

이상혁,김무진행,이은희,서신영,육기환,최태규,Lee, Sang-Hyuk,Kim, Mu-Jin-Haeng,Lee, Eun-Hee,Suh, Shin-Young,Yook, Ki-Whan,Choi, Tae-Kyou 한국정신신체의학회 2004 정신신체의학 Vol.12 No.2

Objectives: The aim of this study was to examine the effectiveness of a qigong-based stress management program in pregnant women. Method: A 8 week controlled clinical trial compared 52 pregnant women assigned qigong-based stress management program to 40 pregnant women assigned pregnancy health education program. Edinburgh postnatal depression scale(EPDS), Beck depression inventory(BDI), Spielberger trait state inventory-1(STAI-1), Hamilton depression rating scale(HAM-D), Hamilton anxiety scale(HAM-A) were used to measure anxiety and depression level. Result : Qigong-based stress management group showed significant improvement compared to the education control group on four measures above. Qigong-based stress management group also showed significant improvement at 8 weeks termination on all measures of anxiety and depression compared to pretreatment level. Conclusion : This study showed that qigong-based stress management program can be an effective method for pregnant women.

인공습지 형태에 따른 비점오염저감효율 분석

이상혁,김이형,조혜진,Lee, Sang Hyuk,Kim, Lee Hyung,Cho, Hye Jin 응용생태공학회 2014 Ecology and resilient infrastructure Vol.1 No.2

Studies of non-point pollutant treatment facilities have widely been conducted for a decade, but natural non-point pollutant treatment facilities implemented on roads have not been carried out for the removal efficiency of non-point pollution sources. This study analyzed the removal efficiency of non-point pollution sources from constructed wetlands using monitoring and event mean concentration method. As a result of this study, removal efficiency of general non-point pollution sources as TSS, COD, BOD is relatively good, but removal efficiency of TN, TP, Cr, Zn, Pb is very small or nothing.

경부식도암 및 하부인두암에서 근치적 전후두인두식도절제술 후 위를 이용한 재건술의 의의

이상혁,이상훈,윤호영,김충배,Lee, Sang-Hyuk,Lee, Sang-Hoon,Yoon, Ho-Young,Kim, Choong-Bai 대한위암학회 2007 대한위암학회지 Vol.7 No.4

Purpose: The aim of this study was to analyze the post operative outcome of reconstruction with using the stomach after performing total pharyngolaryngoesophagectomy in patients with hypopharyngeal cancer or cervical esophageal cancer. Materials and Methods: We conducted a retrospective chart review of 23 patients who underwent gastric pull up for esophageal substitution at the Department of Surgery, Yonsei University College of Medicine, between January 1991 and December 2006. All the patients had transhiatal esophagectomy performed without thoracotomy. Results: There were seventeen males and six females with a median age of 58.1 years (range: 40-70 years). 19 cases were hypopharyngeal cancer, 13 cases had cancer in the pyriform sinus, 15 cases had cancer in the postcricoid area and one case had cancer in the glottic area. The rest were cervical esophageal cancers. The pathologic result was squamous cell carcinoma in all cases. The median total follow-up period was 33 months (range: 1-62 months) and there were two (8.6%) postoperative deaths: one was due to carotid rupture and the other was due to hepatic failure with liver metastasis. The complications were leakage in 1 patient (4.4%), pneumothorax in 1 patient (4.4%) and pneumonia in 1 patient (4.4%). Conclusion: The use of stomach for esophageal reconstruction has many benefits for treating hypopharyngeal cancer or cervical esophageal cancer, So, we made sure there was a sufficient length for the anastomosis after pharyngolaryngoesophagectomy and a rich blood supply from the stomach. There was a low incidence of the leakage at the anastomotic site, along with a low incidence of stenosis and bleeding.

양성 성대 병변의 비수술적 치료

이상혁,Lee, Sang Hyuk 대한후두음성언어의학회 2015 대한후두음성언어의학회지 Vol.26 No.2

Benign vocal fold lesions, such as vocal nodules, polyps and Reinke's edema, usually result from chronic voice overuse. Conservative management such as voice therapy and pharmacotherapy are used as the primary treatment techniques. The main purpose of voice therapy is to identify and reduce voice misuse to achieve the optimal voice. But complete resolution may not be possible in all patients after voice therapy. Furthermore, some patients with voice-related occupations, voice rest and voice therapy are sometimes difficult, which makes it hard to carry out the treatment. When conservative therapy is ineffective, laryngeal microsurgery can be performed under general anesthesia. However, potential complications following laryngeal suspension and violation of the layered structure of the vocal fold during surgery should be considered before surgery. In recent decades, emerging literatures have demonstrated the potential usefulness of vocal fold steroid injection as an alternative treatment option for benign vocal fold lesions. The most advantageous feature of vocal fold steroid injection is the maintenance of regional anti-inflammatory effects while preventing the potential systemic adverse effects of the steroid. Many non-surgical treatment methods can be conducted using different approaches in the office setting. It can be applied as an alternative treatment modality for the management of various benign vocal fold lesions.

후두 결핵의 후두 내시경 소견과 임상 양상 분석

이상혁,이승석,이노희,반재호,이경철,진성민,Lee, Sang-Hyuk,Lee, Seung-Suk,Lee, No-Hee,Ban, Jae-Ho,Lee, Kyung-Chul,Jin, Sung-Min 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.1

Background and Objectives: There has been a gradual decline in the incidence of laryngeal tuberculosis due to effective an-tituberculous chemotherapy and improvement in the standard of living. During the last decade, however, the disease has changed its clinical pattern. We aimed to study a clinical and telescopic evaluation of laryngeal tuberculosis. Materials and Method: A retrospective clinical analysis was done for 16 patients who diagnosed laryngeal tuberculosis from January 2000 through December 2004. All patients had a complete clinical and laboratory work-up including telescopy, chest X-rays, sputum cultures, Tbc PCR(polymerase chain reaction). Laryngeal biopsies were performed in some cases. All the patients received proper antituberculous chemotherapy. Results: The patients age ranged from 21 to 59 with a mean age 43. The male to female ratio was 10:6. The prominent presenting symptom was hoarseness. The various telescopic findings were categorized: 7 patients showed ulcerative, 4 patients granulomatous, 3 patients ulcerofungative, 2 patients had nonspecific inflammatory lesions. Involving sites were true vocal cord most commonly in 12 patients. Three of 16 patients had normal chest X-ray fmding. Among 16 patients, 4 patients showed positive response for AFB stain, 13 patients showed positive for Tbc PCR. Biopsy was done for 3 patients who were not confirmed in initial tuberculous test. All patients responded satisfactorily to antituberculous medication. Conclusion: The telescopic findings and clinical manifestations of laryngeal tuberculosis have changed and seemed to be different from those of classic reports. Thus, the clinicians who deal with the various symptoms and diseases should be aware of the existence of laryngeal tuberculosis and the changing patterns of the disease.

보툴리눔 독소의 약리

이상혁,이현섭,진성민,Lee, Sang Hyuk,Lee, Hyun Sub,Jin, Sung Min 대한후두음성언어의학회 2012 대한후두음성언어의학회지 Vol.23 No.2

Botulinum toxins are the most potent toxins known to mankind. Botulinum toxin acts by blocking the cholinergic neuromuscular or the cholinergic autonomic innervation of exocrine glands and smooth muscles. Seven distinct antigenic botulinum toxins (A, B, C, D, E, F and G) produced by different strains of Clostridium botulinum have been described and only A and B type of botulinum toxins were clinically used. Toxins were consisted of a heavy chain with a molecular weight of 100 kD and a light chain with a molecular weight of 50 kD. Toxins are bound with an astounding selectivity to glycoprotein structures located on the cholinergic nerve terminal. Subsequently light chain of toxin is internalized and cleaves different proteins of the acetylcholine transport protein cascade transporting the acetylcholine vesicle from the intracellular space into the synaptic cleft. After a decade of therapeutic application of the toxin, no anaphylaxis or deaths have been reported and systemic adverse effects have not been reported so far. However the toxin's immunologic properties can lead to the stimulation of antibody production, potentially rendering further treatments ineffective. Botulinum toxin is a safe and effective treatment. Use of botulinum toxin in clinical medicine has grown exponentially in recent years, and many parts of the human body are now being targeted for therapeutic purposes.

기후변화에 따른 우리나라 미선나무의 분포변화 예측

이상혁,최재용,이유미,Lee, Sang-Hyuk,Choi, Jae-Yong,Lee, You-Mi 충남대학교 농업과학연구소 2011 Korean Journal of Agricultural Science Vol.38 No.2

Changes in biota, species distribution range shift and catastrophic climate influence due to recent global warming have been observed during the last century. Since global warming affects various sectors, such as agriculture and vegetation, it is important to predict more accurate impact of future climate change. The purpose of this study is to examine the observed distribution of Abeliophyllum distichum in the Korean peninsula. For this purpose, two period (present and future) climate data were used. Mean data between 1950 and 2000, were used as the present value and the year 2050 and 2080 data from A1B senario in IPCC SRES were used for the future value. Potential habitation is analyzed by MaxEnt(Maximum Entropy model), and Abeliophyllum distichum's coordinates data were used as a dependent variable and independent variables are composed of environmental data such as BioClim, altitude, aspect and slope. The result of six types GCM mean calculation, the potential habitability decreased by 40-60% of the average existing distribution. The methodogies and results of this research can be applicable to the climate changing adaptation stratiegies for the biodiversity conservation.

공황장애 약물 치료에 대한 한국형 알고리듬 개발(3) - 인지행동치료 -

이상혁,양종철,윤세창,서호석,김찬형,유범희,김민숙,Lee, Sang-Hyuk,Yang, Jong-Chul,Yoon, Se-Chang,Suh, Ho-Suk,Kim, Chan-Hyung,Yu, Bum-Hee,Park, Min-Sook 대한불안의학회 2008 대한불안의학회지 Vol.4 No.1

Objective : A working group of psychiatrists from the Korean Academy of Anxiety Disorders was established to determine the appropriate medication algorithm for treating patients with panic disorder. In this article, we discussed the consensus among psychiatrists regarding the use of cognitive behavior therapy (CBT) in the development of a treatment algorithm for panic disorder in Korea. Methods : Based on the guidelines or algorithms published by the American Psychiatric Association, National Institute for Clinical Excellence, and Canadian Psychiatric Association, we constructed questionnaires regarding the core components and contents of CBT for patients with panic disorder. Fifty-four experts in panic disorder completed the questionnaires. Results : There was statistically significant consensus among the experts in the belief that cognitive reconstruction and psychological education are the core components of CBT for the treatment of patients with panic disorder. However, there was some inconsistency between the opinions of some experts regarding the content and frequency of CBT and the results of studies published outside of Korea. Conclusions : CBT, especially the psychological education and cognitive reconstruction components, should be considered when treating patients with panic disorder. However, further consideration needs to be put into the design of a more detailed treatment guideline for the use of CBT in the treatment of patients with panic disorder.

상완골 골절에 동반된 요골 신경 마비 환자에서 초음파 검사의 유용성 - 술기 보고 -

이상혁,성창민,박형빈,Lee, Sang-Hyuk,Sung, Chang-Min,Park, Hyung-Bin 대한정형외과초음파학회 2012 대한정형외과 초음파학회지 Vol.5 No.1

Primary radial nerve palsy occurs in association with approximately 10% of humerus shaft fractures. Secondary radial nerve palsy, which is iatrogenic, occurs in association with approximately 10% to 20% of humerus shaft fractures. Whether the radial nerve palsy is caused primarily by the fracture or secondarily by the surgery, it is necessary to determine whether the radial nerve is being disrupted or compressed by the surrounding structures. This evaluation will dictate whether to await natural recovery or to perform surgical exploration. The current authors report one case of primary radial nerve palsy, due to the humerus fracture, and one case of secondary radial nerve palsy, associated with the osteosynthesis procedure. In both patients, the radial nerve was assessed for anatomical integrity with ultrasonography. Nerve disruption was found in one patient, and a sural nerve graft was performed. Nerve adhesion was found in the other patient, and neurolysis was performed. In both cases, the clinical results were satisfactory. This report focuses on the usefulness of ultrasonography in radial nerve assessment in patients with radial nerve palsy.

후두 내시경의 진단적 역할

이상혁,Lee, Sang-Hyuk 대한후두음성언어의학회 2010 대한후두음성언어의학회지 Vol.21 No.1

Diagnosis of a patient with dysphonia begins with a thorough history and physical examination. Larynx can be visualized either indirectly or directly with a rigid or flexible laryngoscope. One notable limitation of simple indirect laryngoscopy is that the examination dose not yields a recordable and reproducible image of the larynx and vocal tract. And unaided human eye is unable to visualize the vibratory patterns of the true vocal cord during phonantion. When available, stroboscopy provides useful information regarding vocal told closure, vibration, and mucosal wave which is useful to decide between microsurgery, vocal reeducation or a combined treatment Even there are some limitations, recognition of the advantages and disadvantages of stroboscopy allows for optimal appreciation and stroboscopy remains an essential diagnostic tool in the assessment of dysphonia.