http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Clinical Features and Treatment Outcomes of Seronegative Pediatric Autoimmune Encephalitis
이상보,김흥동,이준수,강훈철,김세희 대한신경과학회 2021 Journal of Clinical Neurology Vol.17 No.2
Background and Purpose New diagnostic criteria for pediatric autoimmune encephalitis (AIE) have been introduced recently. A substantial proportion of cases of pediatric AIE are diagnosed as seronegative based on these criteria, and so the clinical characteristics of this group remain to be investigated. Methods This study included 46 pediatric patients younger than 18 years with suspected AIE. Clinical features, laboratory or radiological findings, and treatment outcomes were compared between seronegative and seropositive patients. Results Nine (19.6%) of the 46 patients were diagnosed as seropositive AIE. All of the patients with seropositive AIE had anti-N-methyl-D-aspartate receptor antibodies. Commonly identified neuropsychiatric symptoms were altered mental status, cognitive dysfunction, seizure, speech dysfunction, and psychotic disorder in both the seronegative and seropositive groups. Immunotherapy produced favorable treatment outcomes in both the seropositive (n=7, 77.8%) and seronegative (n=35, 94.6%) AIE patients. Treatment outcomes for first-line immunotherapy were better in seronegative AIE than seropositive AIE patients (p=0.003), and hence a smaller proportion of seronegative patients required second-line treatment (p=0.015). Conclusions Pediatric seronegative AIE patients showed clinical presentations similar to those of seropositive AIE patients, with favorable treatment outcomes after immunotherapy.
이상보,홍상태,전만술 대한안전경영과학회 2000 대한안전경영과학회 학술대회논문집 Vol.2000 No.05
This paper is an integrated system with Manure Pallet Pool System(MPPS) and Agricultural products Pallet Pool System(APPS). This is an management tool that helps to successfully reduce logistics cost and improve pallet availability. It allows enterprise leaders to create profit through system structure improvement. Already traditional PPS is implemented by pallet rental company, but it is irrationally. In the integrated system proposed MPPS-and-APPS, this describes how to combine and implement and measure rental pallet rate. Using a newly developed management technique for MPPS-and-APPS, i.e., 2-dimensional contract, this system can motivate manager and employee to develop their company Furthermore, this paper is useful of performance measure and application in operational unit.