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      • SCOPUSKCI등재

        기관지 확장증의 임상적 고찰

        이두연,조범구,홍승록,Lee, Doo Yun,Cho, Bum Koo,Hong, Sung Nok 대한흉부심장혈관외과학회 1976 Journal of Chest Surgery (J Chest Surg) Vol.9 No.2

        During the past fifteen and one half years, a total of 64 cases of bronchiectasis were treated by pulmonary resection. The diagnosis of bronchiectasis was made relatively easily and accurately with bronchography. The average age of onset in the present series was 21 years old. Preoperative bronchograms were taken in all cases and revealed involvement of the left lower lobe in 14 cases, the right lower lobe in one case, the right upper lobe in 3 cases, the left lower lobe anal lingular segment in 9 cases, and multilobar involvement in cases. Bronchographically 18 tubular and II saccular and 2 cystic and 2 saccular and tubular forms were noted. Various types of pulmonary resection were performed on 59 cases. Complication developed in two cases. One showed pulmonary vein bleeding and was treated completely by reoperation; the other case developed empyema.

      • SCOPUSKCI등재

        흉총창에 의한 심방파열 치험 2례

        이두연,곽상룡,Lee, Doo-Yun,Kwack, Sang-Ryong 대한흉부심장혈관외과학회 1980 Journal of Chest Surgery (J Chest Surg) Vol.13 No.1

        We have experienced 2 cases of the hunshot wound sof the chest involving cardiac injuries at department of the thoracic surgery, Capital Armed Forces General Hospital during I year from April I 1979 to Jan. 1980. In one case of two patients , he was a 22 years old man who was transported to this emergency room 4 hour 10 minutes after having gunshot wound of the left chest by helicopter. Physical examination showed small inlet in left 3rd ICS and left parasternal border, large outlet in left 8th ICS and left scapular line, no breath sound on left side and distant heart sound. chest roentgenography demonstrated marked pleural effusion in left side and mediastinum shifted to right. As soon as chest X-ray was taken, the bleeding through penetrating wound became profuse and cardiac arrest ensued. Closed chest cardiac massage was started and vigorous transfusion continued, but no effective cardiac activity could not be obtained. The patient was pronounced dead due to exsanguinating hemorrhage from wuwpected cardiac wounds. In this critically injured patient with evidence of intrathoracic hemorrhage and suspected cardiac penetration, only emergency thoracic exploration and immediate surgical control of bleeding points might offer the maximum possibility of survival. The other case was a 23 years old man who was transferred to the emergency room 4 hours 50 minutes after having kmultiple communicated fractures of sternum and linear fracture of right mandible by a missile. Examination revealed about 30% skin loss of the anterior chest wall, weak pulse of 96 beats/min., distant heart sound and decreased breath sounds bilaterally. finding on the chest X-ray films showed multiple sternal fractures, marked pericardial effusion indicating hemopericardium. So, the patient was moved immediately to the operation room where, after endotracheal tube inserted, a median sternotomy was performced. A hemorrhagic congestion of the right upper lobe and marked bulging pericardium were disclosed. The pericardium was opened anterior to right phrenic nerve and exsanguinating hemorrhage ensued from the 0.5cm lacerated wound in the auricle of right atrium. The rupture site of right atrium was occluded with non-crushing vascular clamps and then was over sewn with interrupted sutures. It was thought to be highly possible that he was alive long enough to have cardiorrhaphy because of cardiac tamponade, which prevented exsanguinating hemorrhage. He was taken closed reduction for linear fracture of right mandible 2 weeks after repair of ruptured right auricle in dental clinic. This patient's post-operative course was not eventful.

      • KCI등재

        진단이 지연되었던 횡격막 파열 -2예-

        이두연 ( Doo Yun Lee ),방정현 ( Jung Hyun Bang ),김호경 ( Ho Kyung Kim ),김상진 ( Sang Jin Kim ) 대한외상학회 1990 大韓外傷學會誌 Vol.3 No.1

        The diaphragmatic rupture is very rare disease which have to be repaired with emergency operative procedures. But this diaphragmatic rupture could not be detected in early period because of emergency care of other critical combined injuries in some cases. We had experienced 2 cases who had the delayed repair of diaphragm, 9 months, and 10 years after primary treatment of major lesions due to car accident in the Department of Thoracic and Cardiovascular surgery Yonsei University Collge of medicine recently. The two cases are uneventful in postoperative courses 4 months and 1 years after the repair of ruptured diaphragm.

      • SCOPUSKCI등재
      • SCOPUSKCI등재
      • SCOPUSKCI등재

        결핵성 경부 림프절염의 임상 양상과 치료

        함석진,백효채,이두연,김관욱,최형윤,유우식,Haam, Seok-Jin,Paik, Hyo-Chae,Lee, Doo-Yun,Kim, Kwan-Wook,Choi, Hyung-Yoon,Yu, Woo-Sik 대한흉부심장혈관외과학회 2010 Journal of Chest Surgery (J Chest Surg) Vol.43 No.6

        배경: 결핵성 경부 림프절염은 말초 결핵성 림프절염의 가장 흔한 형태이다. 미국흉부학회 (American Thoracic Society)에서는 말초 결핵성 림프절염의 치료에 대해 6개월간의 isoniazid와 rifampin, ethambutol, pyrazinamide 투여를 권유하고 있으나 이런 치료에도 불구하고 결핵성 경부 림프절염의 경우는 실제 임상에서 재발하는 환자를 흔하게 볼 수 있다. 대상 및 방법: 1997년 2월부터 2007년 2월까지 본원에서 결핵성 경부 림프절염으로 진단 및 치료를 받은 38명의 의무기록을 후향적으로 분석하여 임상 양상과 치료 효과를 살펴보고자 하였다. 결과: 남자는 14명(36.8%)이었고 여자는 24명(63.2%)이었으며 평균 나이는 $36.9{\pm}16.3$세였다. 다른 특별한 증상 없이 경부의 종괴 촉지로 내원한 환자가 24명(63.2%)으로 가장 많았고 발열과 오한이 10명(26.3%)이었으며, 흉부 방사선 검사상 이상 소견을 보인 환자는 9명(23.7%)에 불과하였다. 모든 환자는 첫 2개월간 isoniazid, rifampin, ethambutol, pyrazinamide의 투여와 5개월 이상의 isoniazid, rifampin, ethambutol을 투여 받아 최소 7개월 이상의 항결핵제를 투여 받았다. 추적관찰 기간 중 7명(21.2%)의 환자에서 재발이 관찰되었다. 결론: 결핵성 경부 림프절염은 대부분의 환자에서 증상이 없고 방사선 검사상에서도 이상 소견을 보이지 않기 때문에 진단과 치료가 늦어지는 경향이 있다. 항결핵제의 투여에도 불구하고 비교적 높은 재발률을 고려할 때, 미국흉부학회에서 권장하는 6개월간의 치료보다는 더 장기간의 치료가 필요할 것으로 생각된다. Background: Cervical tuberculous lymphadenitis is the most common form of peripheral tuberculous lymphadenitis. The American Thoracic Society recommends 6 months of isoniazid, ritampin, ethambutol and pyrazinamide for treatment of peripheral tuberculous lymphadenifls, but even with this recommended treatment, frequent relapse occurs in actual clinical situations. Material and Method: The medical records of 38 patients diagnosed and treated for cervical tuberculous lymphadenitis between February 1997 and February 2007 were retrospectively reviewed. Result: The study included 14 males (36.8%) and 24 females (63.2%), with a mean age of $36.9{\pm}16.3$ years. The most frequent symptom was palpable neck mass in 24 patients (63.2%); 10 patients (26.3%) complained of fever or chills. Only nine patients (23.7%) had radiologic abnormalities. All patients received anti-tuberculous medications for at least 7 months, with isoniazid, rifampin, ethambutol and pyrazinamide for the first 2 months, and then isoniazid, rifampin and ethambutol given for more than 5 months. Relapse occurred in 7 patients (21.2%). Conclusion: Since many patients with cervical tuberculous lymphadenitis have no symptoms and show no radiologic abnormalities, diagnosis and treatment tend to be delayed. Considering the high relapse rate, the anti-tuberculous medication period should be longer than 6 months and this is recommended by the American Thoracic Society.

      • 흉강 내시경을 이용한 식도 중봉 낭종 수술 치험 -1례-

        박성용,김태훈,이두연,김은영,전세은,조상호,Park, Seong-Yong,Kim, Tae-Hoon,Lee, Doo-Yun,Kim, Eun-Young,Jeon, Se-Eun,Cho, Sang-Ho 대한기관식도과학회 2007 大韓氣管食道科學會誌 Vol.13 No.1

        Esophageal duplication cyst is very rare mediastinal tumor which is congenital lesion of the esophagus. Esophageal duplication cyst could be excised with video assisted thoracoscopic surgery(VATS) if it is relatively small, cystic lesion and not adhered severely to the surrounding tissues such as lung, trachea, bronchus, esophagus and pleura. We report a case of an esophageal duplication cyst which was located in the right thoracic cavity below carina and could be excised completely and repaired by interrupted suture with 3.0 black silk. The patient was discharged at 10 days after operation with good condition and has been in uneventful condition 2 months after operation.

      • 식도 파열의 수술적 치료

        황정주,정은규,이두연,백효채,Hwang Jung Joo,Joung Eun Kyu,Lee Doo Yun,Paik Hyo Chae 대한기관식도과학회 2005 大韓氣管食道科學會誌 Vol.11 No.1

        Background : It is well-known that esophageal perforation (EP) is difficult in diagnosis and has high mortality rate despite proper management. There are disputes in regarding the reatment in cases of delayed diagnosis although in the early diagnosed cases, operation is recommended without arguments. Methods: From April, 2001 to December, 2004, nine patients who were diagnosed as EP in our hospital were analyzed retrospectively about the causes, the interval between the cause and the treatment, and operation methods. Results: There were 8 male and one female with men age of 49.3 years (range: 25-67 years). The causes of EP included perforations following operations of corvical spine in three cases, spontaneous perforation(Boehaave syndrome) in two cases, foreign bodies in two cases, operation of esophageal diverticulum in one case and blunt trauma bytraffic accident in one case. Mean interval between the first treatments and the causes was 11.6 days (range: 2-30 days). The sites of perforation were upper third of esophagus in three cases, middle third in three cases and lower third in three cases. All except two cervical cases presented as mediastinitis or empyema at the time of diagnosis. Primary repair and irrigation had been performed in 7 cases but five cases out of them required more than two procedures. Conclusions : More than one procedure wasrequired in the treatment of EP because of contaminations and infections which had been spread at the time of initial manifestatios, howeverprimary closure and massive irrigation is the best method in order to preserve esophagus unless the remaining esophagus is extensively damaged.

      • SCOPUSKCI등재

        종양 표지 인자로서 혈장 Transforming Growth Factor-β1에 대한 연구

        신훈,임창기,최인영,이두연,노동영,류민희,이효석,방영주,박종섭,진승원,Shin, Hoon,Lim, Chang Ki,Choi, In Young,Lee, Doo Yun,Noh, Dong Yong,Ryu, Min Hee,Lee, Hyo Suk,Bang, Yung Jue,Park, Jong Sup,Jin, Seung Won 대한면역학회 2001 Immune Network Vol.1 No.2

        Background : Many investigators have found transforming growth factor-${\beta}1$ (TGF-${\beta}1$) to be elevated in tumors. Changes in responsiveness to TGF-${\beta}1$ have been linked to malignant transformation, tumor progression and tumor regression. Many malignant cell lines of epithelial or hematopoietic origin are refractory to the antiproliferative effects of TGF-${\beta}1$. However, a little is known about the association of TGF-${\beta}1$ with progression of malignant tumor. Methods : In this study, we measured the plasma level of TGF-${\beta}1$ in various cancer patients and evaluated the utility of plasma TGF-${\beta}1$ as a possible tumor marker. Plasma TGF-${\beta}1$ levels were measured using enzyme-linked immunosorbent assay in cancer patients and normal controls. Carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) as tumor marker were compared with TGF-${\beta}1$ in the aspects of sensitivity and specificity. Results : The mean of plasma TGF-${\beta}1$ levels was $1.219{\pm}0.834ng/ml$ in normal controls, $5.491{\pm}3.598ng/ml$ in breast cancer, $12.670{\pm}10.386ng/ml$ in lung cancer, $5.747{\pm}3.228ng/ml$ in hepatocellular carcinoma and $10.854{\pm}7.996ng/ml$ in cervical cancer. In comparison with CEA and AFP, TGF-${\beta}1$ is more sensitive. Conclusion : We conclude that the high levels of TGF-${\beta}1$ are common in the plasma of cancer patients. These results suggest that the plasma TGF-${\beta}1$ level can be a potent tumor marker in various cancer patients.

      • SCOPUSKCI등재

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