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      • KCI등재

        Cyanidin 3-O-glucoside Isolated from Lonicera caerulea Fruit Improves Glucose Response in INS-1 Cells by Improving Insulin Secretion and Signaling

        이다혜,함정엽,강기성,이해정 대한화학회 2016 Bulletin of the Korean Chemical Society Vol.37 No.12

        Cyaniding 3-O-glucoside is a flavonoid compound isolated from the fruits of the Lonicera caerulea. In the present study, we investigated the effects of L. caerulea extract and its active component cyaniding 3-O-glucoside on insulin release in INS-1 cells. L. caerulea extract and cyanidin 3-O-glucoside activated the secretion of insulin that lead to diminished glucose production in INS-1 cells. Cyanidin 3-O-glucoside also enhanced the phosphorylation of insulin receptor, insulin receptor substrate 1, and phosphoinositide 3-kinase protein expressions in INS-1 cells. These results suggest that cyanidin 3-O-glucoside is an active component of L. caerulea that enhances insulin production and activates insulin signaling.

      • KCI등재

        법과 정치경제학(Law and Political Economy) : 불평등의 시대, 법사회학에서 ‘경제적인 것’의 부활과 그 현대적 의미

        이다혜 법과사회이론학회 2025 법과 사회 Vol.- No.79

        역사상 인류가 불평등으로부터 온전히 자유로웠던 시기는 없었지만, 근래에는 극심한 양극화가 더욱 중요한 화두가 되었다. 정치의 위기와 경제의 위기는 불가분의 관계이다. 경제적 불평등에 대한 해법을 찾고자 한다면 정치적 지형과 맥락에 대한 이해 없이 불가능하고, 또한 경제구조와 그 현실에 대한 이해 없이 정치의 영역에서 발생하는 현상을 온전히 이해할 수 없다. 이러한 맥락에서 최근 정치경제학(political economy)의 중요성이 법사회학 분야에서 재조명되고 있다. 현대 법사회학의 중요한 과제 중 하나는 ‘경제적인 것’에 다시금 천착하는 것이다. 최근 미국에서는 법사회학 분야에서 주목할 만한 중요한 변화의 흐름이 감지되고 있다. 과거의 법현실주의(legal realism), 법과사회운동(law and society movement), 비판법학(critical legal studies)과 기본적인 문제의식을 같이하며 계승・발전시키되 21세기의 경제적 양극화의 심화와 민주주의에 대한 위협이라는 이중의 위기에 대한 보다 근본적인 법이론적 대응이 필요하다는 것을 전제로, ‘법과 정치경제학’(Law and Political Economy, ‘LPE’)이라는 이름의 학문적 사조가 부상하여 활발한 움직임을 보이고 있다. LPE의 주요한 학문적 지향성 및 특징으로 첫째, 시장중심적 자본주의 체제를 고정불변의 진리로 보지 않고 정치경제학 관점에서 현재의 불평등 문제에 대한 비판적 분석을 개진하고 있는 점, 둘째, 자본주의에 있어 법의 선분배적(pre-distribution) 기능을 조명하며 법이 불평등을 고착화하는 기제가 될 수도 있지만 반대로 양극화를 해소하고 평등을 위한 여정의 도구가 될 수도 있다는 양면성에 대해 논의하고 있는 점, 셋째, 연구방법론에 있어 법학과 타 분야 간에 명목적인 수준을 넘어 진정한 의미에서의 학제간 연구가 수행되고 있다는 점 등을 꼽을 수 있다. 본 논문에서는 먼저 전제적 논의로서 18세기 산업혁명 이후 정치경제학의 개념과 연혁적 전개를 검토한 뒤(II), 법과 정치경제학(LPE)의 부상과 그것이 지향하는 목적, 주요 논의대상, 연구방법론상의 특징 등을 개괄적으로 살펴본다(III). 이러한 논의 위에서 법과 정치경제학의 핵심적인 시사점이 될 ‘정치경제학의 법사회학’을 모색한다. 칼 폴라니의 이중운동(double movement) 개념에 착안하여, 정치경제학의 중요한 법사회학적 시사점으로서 ‘이중운동의 법사회학’(legal sociology of double movement)이라는 이론을 제시한다. 이중운동의 본질은 시장확대적 움직임과 사회보호적 움직임 사이의 권력 겨루기다. 이러한 움직임은 법과 제도를 통해 성립되고, 기득권으로서 존속하기도 하고, 때로는 성립된 기득권이 약자와 소수자에 의해 도전받아 해체되기도 한다. 폴라니가 말하는 시장확대적 운동과 사회보호적 운동의 대립이라는 이중운동 이론을 법사회학의 관점으로 재해석하면 ‘시장확산에 기여하는 법’과 ‘사회보호에 기여하는 법’ 사이의 대립, 긴장, 갈등과 조화, 성립과 해체의 역동적인 과정이 발견된다. 이는 법철학적 관점에서는 법형식주의 대(對) 법현실주의의 대립이기도 하다. 또한 실정법에서 이중운동이 발현되는 방식은 ‘법적 허구’ 대 ‘법적 실질’의 대립이기도 하다는 점을 구체적인 사례를 살펴보며 논증한 뒤, 이러한 정치경제학적 관점을 적용할 실천적 필요성이 큰 주제인 젠더 및 인공지능에서의 불평등 문제에 이를 적용하여 살펴본다(IV). 마지막으로 불평등과 ... There has never been a time in human history completely free from inequality, but in recent times, extreme polarization has emerged as one of the most critical issues. The crisis of politics and the crisis of the economy are inseparable. Any attempt to find a solution to economic inequality is impossible without an understanding of the political landscape and context, just as it is impossible to fully comprehend political phenomena without an understanding of economic structures and realities. Within this context, the importance of ‘political economy’ is being reexamined in the field of sociology of law. One of the key tasks of contemporary sociology of law is to re-engage with ‘the economic.’ In the United States, a notable shift is taking place within the field of sociology of law. While inheriting the core concerns of past movements such as legal realism, the law and society movement, and critical legal studies(CLS), there is now a growing recognition of the need for a more fundamental theoretical response to the dual crisis of deepening economic polarization and the threat to democracy in the 21st century. This has led to the emergence of a scholarly movement known as ‘Law and Political Economy’ (LPE), which is gaining momentum. The main academic orientations and characteristics of LPE include, first, its refusal to accept market-centered capitalism as an immutable truth and its critical analysis of current inequality issues from the perspective of political economy; second, its focus on the ‘pre-distributive’ role of law within capitalism, recognizing the dual nature of law—as both a mechanism that can entrench inequality and a tool that can help overcome polarization and promote equality; and third, its commitment to genuine interdisciplinary research that goes beyond nominal collaboration between law and other disciplines. This paper will first examine the concept and historical development of ‘political economy’ since the Industrial Revolution of the 18th century as a foundational discussion (II). It will then outline the emergence of Law and Political Economy (LPE), its objectives, primary areas of discussion, and methodological features (III). Building on this discussion, the paper will explore and identify the points where political economy and law intersect, analyzing their implications and significance from a sociological perspective of law—an effort to conceptualize a ‘sociology of law of political economy’ (IV). Finally, in light of the extreme inequality and polarization we face today, the paper concludes by emphasizing that the ‘sociology of law of political economy’ ultimately signifies the restoration or revival of ‘the economic’ within the field of sociology of law, adding a few final reflections (V).

      • KCI등재

        Cirsimaritin Contributes to the Estrogenic Activity of Cirsium japonicum var. maackii through the Activation of Estrogen Receptor α

        이다혜,정유정,백지윤,신명숙,이상현,함대현,이상천,심재석,김수남,강기성 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.12

        Phytoestrogens are naturally occurring plant-derived chemicals that exert female hormone-like activities similar to those of endogenous estrogens. The purpose of this study was to quantitate the estrogenic activity of six chemical constituents (apigenin, hispidulin, cirsimaritin, cirsimarin, pectolinarin, and linarin) of Cirsium japonicum var. maackii using several in vitro assays. Reporter gene activation by each compound was examined using a human breast cancer (MCF-7) cell-based transactivation assay. Proliferative activity was also examined using MCF-7 cells. Reporter gene activation in MCF-7 cells by cirsimaritin was significantly suppressed by co-administration of the estrogen receptor (ER) antagonist ICI 182,780, indicating that cirsimaritin is an ER agonist. Under experimental conditions simulating postmenopausal syndrome (i.e., a low concentration of estrogen), cirsimaritin exerted beneficial effects on MCF-7 cells by increasing estrogenic activity. These results suggest that cirsimaritin is an effective estrogenic compound that can improve postmenopausal symptoms.

      • KCI등재

        비틀어진 형상(Twisted)을 가지는 고층 구조물의 역학적 특성 분석

        이다혜,김현수,강주원,Lee, Da-Hye,Kim, Hyun-Su,Kang, Joo-Won 한국공간구조학회 2020 한국공간구조학회지 Vol.20 No.4

        In this study, structural characteristics were analyzed by combining gravity load and lateral loads such as seismic loads through static analysis of example structures, and the static characteristics of the twisted structure according to the plane rotation angle were also analyzed. Example structures were selected as regular structure, and twisted structures; 1.0, 2.0, and 3.0 degree angle of rotation per story, and static analysis was performed by the load combination case 1 and case 2. As a result the story drift ratio of the twisted-shaped structure also increased as the plane rotation angle per story increased. The eccentricity according to the load combination was the highest in the lower stories of all analysis models, and the eccentricity was found to be larger as the rotation angle decreased. The twisted-shaped structure was more responsible for the bending moment of the column than the regular structure, and the vertical member axial force of all analysis models was almost similar.

      • KCI등재후보

        자극제시 방법과 동사유형에 따른 발달지체 유아의 동사 정의하기

        이다혜,최상배 공주대학교 특수교육연구소 2021 특수교육논집 Vol.26 No.1

        The objective of this study is to understand the qualitative differences and characteristics of verb definition of preschoolers with developmental delay according to the stimulus presentation methods. The stimulus presentation methods were composed of three types such as auditory stimulus presentation, audiovisual stimulus presentation, and animation & vocal stimulus presentation. The research subjects were total 20 preschoolers with developmental delay. In the results of this study, when the audiovisual stimulus was presented rather than the visual stimulus, the definition score was significantly high. When the animation & vocal stimulus was presented rather than the audiovisual stimulus, the score was significantly high. When the animation & vocal stimulus was presented rather than the audio stimulus, the biggest score differences were shown. Second, in the results of verifying differences in definition score according to verb types, the action verbs showed significantly higher definition score than the stative verbs. Third, in the results of understanding the qualitative differences shown in verb definition, it got lowered in the order of general example and personal experience, concrete concept, error, combinational definition, antonym, and hypernym. In the future, it would be necessary to have a follow-up research applying the definition method and systematized method of definition scoring by classifying much more subjects according to the language age.

      • KCI등재

        비정형 구조물의 평면 회전축과 코어의 이동에 따른 지진응답분석

        이다혜,김현수,강주원 한국공간구조학회 2022 한국공간구조학회지 Vol.22 No.1

        When the center of stiffness and the center of mass of the structure differ under the seismic load, torsion is caused by eccentricity. In this study, an analysis model was modeled in which the positions of the core and the plane rotation axis of a 60-story torsional atypical structure with a plane rotation angle of 1 degree per floor were different. The structural behavior of the analysis model was analyzed, and the earthquake response behavior of the structure was analyzed based on the time history analysis results. As a result, as the eccentricity of the structure increased, the eccentricity response was amplified in the high-rise part, and the bending and torsional behavior responses were complex in the low-order vibration mode. As a result of the analysis, the maximum displacement and story drift ratio increased due to the torsional behavior. The maximum story shear force and the story absolute maximum acceleration showed similarities for each analysis model according to the shape of the vibration mode of the analysis model.

      • KCI등재

        한국발레의 선구자 박금자의 춤 생애사 연구

        이다혜,이나라 대한무용학회 2024 대한무용학회논문집 Vol.82 No.3

        The purpose of this study is to examine the development and sig- nificance of Korean ballet through the life of Mrs. Park Geum-ja and to record the findings as part of the history of Korean ballet. The research is based on data collected from documents, video materials, and face-to-face interviews, analyzed using the text interpretation method of life history research from a temporal and chronological perspective. This study emphasizes the impact of Ms. Park's life and her artistic world on the Gwangju and Korean ballet community, and serves as an important document for preserving the achievements of Korea's senior artists

      • KCI우수등재

        MD&A 비정상적 기술과 미래 기업 성과와의 관련성에 관한 연구

        이다혜,변상혁 한국회계학회 2024 회계학연구 Vol.49 No.4

        This study examines whether managers control the textual descriptiveness of non-financial disclosures by studying the relationship between the degree of textual descriptiveness and future firm performance. We classify MD&A(Management Discussion and Analysis) text modifications into normal and abnormal descriptions, investigating their impact on future performance in light of the firm’s disclosure environment. According to the obfuscation hypothesis, managers may choose opaque disclosure to avoid the risks associated with full disclosure, or strategically disclose information they wish to conceal to hinder investor decision-making. The abnormal description represents a deviation from the normal description level of the same industry, aiming to grasp both the incentive for managers to conceal information(under-description) and factors aiming to increase information processing costs(over-description). We observe a negative association between abnormal textual description in MD&A and future firm performance. Notably, this was more prominent in small-sized firms, firms listed on KOSDAQ, firms with a low foreign ownership ratio, and firms without an audit committee. Firms with low visibility have less pressure for clarity, and those with weaker monitoring face fewer checks against manager opportunism. Further analysis confirms that these abnormal descriptions affect long-term investor decisions, potentially as a means to delay market reactions by pre-empting negative news. This study indirectly indicates that managers may manipulate non-financial MD&A disclosures strategically.

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