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이남희 ( Nam Hee Yi ),박승운 ( Seung Woon Park ),박인성 ( In Seong Park ),박치환 ( Chi Hwan Park ),이충원 ( Choong Won Lee ) 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.1
Relapsing polychondritis is an uncommon disease associated with inflammation in cartilaginous tissues throughout the body, particularly affecting the cartilaginous structures of ears, nose, joints, and respiratory tract. Several autoimmune diseases, including vasculitis, are associated with the concurrent relapsing polychondritis. However, ankylosing spondylitis primarily affecting the sacroiliac joints and spine is rare in patients with relapsing polychondritis. We report on a 54-year-old man with concurrently relapsing polychondritis and ankylosing spondylitis. (J Rheum Dis 2015;22:56-60)
증례 : 순환기 ; 독사조신 복용 후 발생한 여성형유방증 1예
박인성 ( In Seong Park ),이남희 ( Nam Hee Yi ),박치환 ( Chi Hwan Park ),박승운 ( Seung Woon Park ),유진석 ( Jin Seok Yu ),정준훈 ( Joon Hoon Jeong ) 대한내과학회 2016 대한내과학회지 Vol.90 No.3
Doxazosin은 알파아드레날린길항제의 대표적인 약으로 전립선비대증에 아주 흔하게 사용되고 있다. 비슷하게 사용되는 finasteride, dutasteride와 같은 5-알파환원효소억제제는 여성형유방증, 유방통과 같은 부작용이 흔하게 보고되고 있으나 알파아드레날린길항제는 보고된 바가 국내에 아직 없다. 또한 알파아드레날린길항제는 약리 기전으로 보아 그러한 부작용을 의심하는 것이 쉽지 않다. 이에 doxazosin 사용 후 일측성의 여성형유방증과 유방통이 발생한 1예를 경험하였기에 국내 첫 번째 사례로 보고하는 바이다. Doxazosin is an adrenergic alpha-1 receptor antagonist used to treat lower urinary tract symptoms that are common in prostatic hyperplasia. To our knowledge, few cases of gynecomastia and mastodynia, as a complication of adrenergic alpha-1 receptor antagonist, have been reported to date; no cases have been reported in Korea. We describe a case involving a 78-year-old man treated for prostatic hyperplasia with 13 months of doxazosin. He complained about unilateral gynecomstia and mastodynia. Five months after the discontinuation of doxazosin, the gynecomastia was significantly improved. This is the first reported case of gynecomastia and mastodynia associated with doxazosin use in Korea. (Korean J Med 2016;90:239-242)
터너증후군 환자의 대동맥 축착증을 스텐트 삽입술로 치료한 증례 1예
박승운 ( Seung Woon Park ),이한철 ( Han Cheol Lee ),이남희 ( Nam Hee Yi ),박인성 ( In Seong Park ),박치환 ( Chi Hwan Park ),유진석 ( Jin Seok Yu ) 대한내과학회 2015 대한내과학회지 Vol.89 No.3
Cardiovascular malformations, such as bicuspid aortic valve and coarctation of the aorta, are more prevalent in patients with Turner syndrome than in the general population. Here, we describe the case of a 35-year-old female with Turner syndrome who was admitted to our hospital with a fever caused by infective endocarditis. Aortic coarctation was diagnosed using computed tomography. The patient was treated with antibiotics and a stent was then implanted. Endovascular therapy using stents is a safe and effective treatment option for aortic coarctation in patients with Turner syndrome. (Korean J Med 2015;89:331-334)