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- 저자 : 은영민 (검색결과 33 건)
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Myocardial Layer-Specific Strain Analysis in Children with Mitochondrial Disease
은영민,이영목 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.1
Purpose: Children with mitochondrial disease (MD) have clinical phenotypes that are more severe than those found in adults. In this study, we assessed cardiac function in children with MD using conventional and advanced echocardiographic measurements, explored any unique patterns present, and investigated the development of early cardiomyopathy (CMP). Materials and Methods: We retrospectively reviewed the medical records of 33 children with MD. All patients underwent transthoracicechocardiography with conventional and advanced myocardial analysis. We compared all data between patients and an age-matched healthy control group. Results: Conventional echocardiographic diastolic measurements of mitral E, E/A, and tissue Doppler E’ were significantly lower and E/E’ was significantly higher in children with MD, compared with the measurements from the control group. There was no significant difference in longitudinal and radial strain between the groups. Circumferential strain in the endocardium (p=0.161), middle myocardium (p=0.008), and epicardium (p=0.042) were lower in patients, compared to the values in controls. Circumferentialstrain was correlated with E’ (p<0.01, r>0.60). Conclusion: In children with MD, myocardial circumferential strain may develop early in all three layers, even with normally preservedlongitudinal and radial strain. This may be an early diagnostic indicator with which to predict CMP in this patient population.
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은영민,노광식,김병길,한상원,Eun Young-Min,Rho Kwang-Sik,Kim Pyung-Kil,Han Sang-Won 대한소아신장학회 1997 Childhood kidney diseases Vol.1 No.1
목적 : 요로 결석은 소아에서는 비교적 드물다고 하나, 점점 증가하고 있으며, 유발요인이 있는 경우에는 보다 빨리 진단할 수 있다. 본 연구를 통하여 요로 결석 환아들의 주증상, 진단, 감염및 동반 질환 여부, 치료 등에 대하여 알아보고자 하였다. 방법 : 1986년 1월부터 1996년 6월까지 10년 5개월간 세브란스 병원에 내원한 15세 미만의 요로 결석환아 45명을 대상으로 후향적 고찰을 하였다. 결과 : 요로 결석 환아의 평균 연령은 6.5세, 남녀비는 5.4:1이었고, 가족력은 13.3%에서 나타났다. 주증상은 육안적 혈뇨가 가장 많았고, 요로 감염을 동반한 환아 46.1%,요로 기형 및 질환을 동반한 환아가 35.6%에서 나타났다. 진단 방법으로는 단순 요로 촬영, 경정맥 신우 조영술, 복부 초음파 등이 사용되었는데, 초음파만으로 진단받은 경우도 다수 있어 의의가 크다고 하겠다. 치료로는 체외 충격파 쇄석술, 경피적 신결석 적출술, 수액 요법, 이뇨제등이 사용되었다. 결론 : 소아 요로결석에 대해 관찰한 결과, 유의할 만한 질환으로 생각되며, 요로 폐색이 있는 환아에서는 시급한 치료가 요구된다. 특히 단순 방사선 촬영및 경정맥 신우 조영술에서 발견되지 않은 환아에서는 반드시 초음파를 하여 진단해야 할 것이다. 한편, 결석의 성분 분석이 이루어지지 않아 다소 아쉬운 점이 남는다. Even though the urinary stones are rare in children, careful observation and monitoring are necessary because the incidence has been increasing. This study is aimed to document the characteristics of urinary stones in children including the symptoms, diagnosis, with or without urinary tract infection, other urinary tract anomaly and treatment. 45 patients under the age of 15 years with urinary stones hospitalized during Jan. 1986 to Jun. 1996 at Severance Hospital were reviewed retrospectively. Patients' mean age was 6.5 years and sex ratio (male : female) was 5.4:1. The most common symptom was gross hematuria. Stones accompanied with urinary tract infection was 46.7%, and stones associated with urinary tract anomaly was 35.6%. Extracorporeal shock wave lithotripsy, percutaneous nephrolithotorny, hydration and diuretics were the treatment modality used. Urinary stone were found to be a significant cause of urinary tract obstruction in children, requiring prompt diagnosis and treatment. Although KUB, IVP, and ultrasonography were commonly used to make the diagnosis, many cases were detected only by ultrasonographic study.
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은영민 ( Young-min Eun ),김민성 ( Min-seong Kim ),오세엽 ( Se-yeop Oh ),신선웅 ( Seon-woong Shin ),김상훈 ( Sang-hoon Kim ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.2
본 논문은 진공을 이용한 흡착방식과 바퀴형 이동방식을 이용하고 환경 탐지용 센서를 부착한 벽면 이동형 로봇의 구현에 관한 연구로서, 대형 구조물의 안전 검사 및 위험한 시설물의 보수 작업등을 보조하기 위한 목적이 있다. 로봇의 무게에 따른 중력을 견딜 수 있도록 강력한 진공흡착방식을 고안하여 다양한 벽면재질에도 견딜 수 있도록 설계하였으며, 바퀴형 이동방식을 택하여 높은 이동성과 제어 능력을 고려하였다. 또한 환경 감지를 위한 센서와 카메라를 부착하여 시각정보 등 유용한 정보를 관리자와 통신을 통해 교환할 수 있도록 하여 지능능력과 활용성을 갖추었다.
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은영민 ( Young-min Eun ),김민성 ( Min-sung Kim ),권혁성 ( Hyeok-sung Kwon ),송용주 ( Yong-joo Song ),김상훈 ( Sang-hoon Kim ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.1
본 논문은 진공을 이용한 흡착방식과 바퀴형 이동방식을 이용하고 환경 탐지용 센서를 부착한 벽면 이동형 로봇의 구현에 관한 연구로서, 대형 구조물의 안전 검사 및 위험한 시설물의 보수 작업등을 보조하기 위한 목적이 있다. 로봇의 무게에 따른 중력을 견딜 수 있도록 강력한 진공흡착방식을 고안하여 다양한 벽면재질에도 견딜 수 있도록 설계하였으며, 바퀴형 이동방식을 택하여 높은 이동성과 제어 능력을 고려하였다. 또한 환경 감지를 위한 센서와 카메라를 부착하여 시각정보 등 유용한 정보를 관리자와 통신을 통해 교환할 수 있도록 하여 지능능력과 활용성을 갖추었다.
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Relationship between serum sodium level and coronary artery abnormality in Kawasaki disease
박소라,은영민,김지홍 대한소아청소년과학회 2017 Clinical and Experimental Pediatrics (CEP) Vol.60 No.2
Purpose: Kawasaki disease (KD) is an immune-related multisystemic vasculitis that occurs in children, especially ensuing from a coronary artery abnormality. Sodium level is known to be related to vascular injury, which could affect the progress of KD. The purpose of this study was to determine the serum sodium levels that could predict the occurrence of cardiac and coronary artery events in KD. Methods: We conducted a retrospective review of medical records for 104 patients with KD from January 2015 to December 2015. Patients with serum Na levels of <135 mEq/L at the time of initial diagnosis were assigned to the hyponatremia group. Laboratory findings and echocardiographic data were analyzed for various aspects. Results: Among the 104 patients with KD, 91 were included in the study, of whom 48 (52.7%) had hyponatremia. The degree of fever, white blood cell count, percentage of neutrophils, percentage of lymphocytes, total bilirubin level, brain natriuretic peptide level, erythrocyte sedimentation rate, and C-reactive protein level were higher in the patients with hyponatremia. They also demonstrated a trend of larger coronary artery diameters based on Z scores. Conclusion: The severity of vascular inflammation in acute KD with hyponatremia might worsen the prognosis of coronary vasculature. Although no statistically significant correlation was found between the initial serum sodium levels and coronary arteriopathy in the patients with KD in this study, a long-term follow-up study with a larger number of enrolled patients should be designed in the future to elucidate the relationship between serum sodium level and coronary arteriopathy in patients with KD.
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Myocardial atrophy in children with mitochondrial disease and Duchenne muscular dystrophy
이태호,은영민,최재영,권혜은,이영목,김흥동,강성웅 대한소아청소년과학회 2014 Clinical and Experimental Pediatrics (CEP) Vol.57 No.5
Purpose: Mitochondrial disease (MD) and Duchenne muscular dystrophy (DMD) are often associatedwith cardiomyopathy, but the myocardial variability has not been isolated to a specific characteristic. We evaluated the left ventricular (LV) mass by echocardiography to identify the general distribution andfunctional changes of the myocardium in patients with MD or DMD. Methods: We retrospectively evaluated the echocardiographic data of 90 children with MD and 42with DMD. Using two-dimensional echocardiography, including time-motion (M) mode and Dopplermeasurements, we estimated the LV mass, ratio of early to late mitral filling velocities (E/A), ratio ofearly mitral filling velocity to early diastolic mitral annular velocity (E/Ea), stroke volume, and cardiacoutput. A “z score” was generated using the lambda-mu-sigma method to standardize the LV masswith respect to body size. Results: The LV mass-for-height z scores were significantly below normal in children with MD(–1.02±1.52, P<0.001) or DMD (–0.82±1.61, P =0.002), as were the LV mass-for-lean body-mass zscores. The body mass index (BMI)-for-age z scores were far below normal and were directly proportionalto the LV mass-for-height z scores in both patients with MD (R=0.377, P<0.001) and those with DMD(R =0.330, P=0.033). The LV mass-for-height z score correlated positively with the stroke volume index(R =0.462, P<0.001) and cardiac index (R =0.358, P<0.001). Conclusion: LV myocardial atrophy is present in patients with MD and those with DMD and may beclosely associated with low BMI. The insufficient LV mass for body size might indicate deterioration ofsystolic function in these patients.
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