치매환자 조호자를 위한 교육지지프로그램의 효과성에 관한 비교연구

송 흡(Heup Song),강재명(Jae Myeong Kang),김병규(Steven B. Kim),조성진(Seong Jin Cho),윤선경(Seon kyung Yun),윤혜진(Hye jin Yoon),연병길(Byeong Kil Yeon) 대한노인정신의학회 2017 노인정신의학 Vol.21 No.1

Objective:We studied the effect of Hyu-Sig-Gong-Gan and Hye-Ah-Rim on several evaluations and compared the two programs. We then investigated factors associated with the difference between pre- and post-ratings. Methods:Thirty-six patients were randomized to Hyu-Sig-Gong-Gan (n=23) or Hye-Ah-Rim (n=13). We tested for the effect of each program on several evaluations and compared the two programs through Zarit Burden Interview (ZBI), Center for Epidemiologic Studies-Depression Scale, Dementia Attitude Scale (DAS)-intelligence, DAS-comfort and DAS-total. We then investigated whether the difference between pre- and post-rating depends on other factors. Results:We observed significant positive effect of Hyu-Sig-Gong-Gan on DAS-comfort (t=1.843, p=0.039) and significant positive effect of Hye-Ah-Rim on ZBI (t=-2.327, p=0.019), DAS-comfort (t=2.241, p=0.022), and EuroQol-5 Dimensions-Visual Analogue Scale (t=2.537, p=0.013). For comparing the two programs, we found a lack of evidence for the difference in any of the five commonly observed evaluations. In the secondary analysis, we observed a strong trend that the two programs were particularly effective for caregivers with negative pre-ratings. Conclusion:The two programs showed positive effects on the various evaluations, but some evaluations could not reach statistical significance. The programs appear to be particularly helpful for those who are in need before the program participation.

체성분 분석과 골연령 측정을 통한 취학 전 아동의 성장에 대한 임상연구

윤혜진,이유진,백정한,Yun, Hye-Jin,Lee, Yu-Jin,Han, Baek-Jung 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.2

Objectives : The purpose of this study is to have better data and to make efficient clinical reviews on pre-school children's growth based on two measurements; Body composition for measuring body volume and bone age for potential growth. Methods : The study was conducted with 221 children(118 of boys and 103 of girls) from three kindergartens. Body compositions(soft lean mass, body fat mass, percent body fat) were measured by bioelectrical impedance analysis, bone age was measured by bone density through ultrasonic image of calcaneus. Results and Conclusions : 1. The higher level on weight or BMI, the more averages of soft lean mass, body fat mass, percent body fat. 2. The average bone ages and bone age-chronological age were lower in under 50 percentile's group, but it was higher in upper 50 percentile's group. Also, children with high BMI had older in bone ages and bone age-chronological age. 3. The higher in height percentile based on the bone age; there were more soft lean mass. 4. The averages of bone age and bone age-chronological age were significantly decreased, the more percentiles of height according to bone age were big, they were higher than total average in under 50 percentile's group of height, lower than total average in over 50 percentile's group of height in both boys and girls. 5. The average of MPH were significantly decreased in top percentiles of children's height distribution. Also, in the upper percentiles of height distribution based on bone age were big in only boys. 6. The body compositions(soft lean mass, body fat mass, percent body fat) were related to body volume growth, which can he measured by weight or BMI. The bone age, bone age-chronological age, and MPH were related in terms of hight. The body volume growth was a little hit related with potential growth.

한국 생명공학 특허 기술 분석

윤혜진,Yun, Hye-Jin 한국특허정보원 2004 Patent 21 Vol.54 No.-

호주의 국가경쟁력 보고서

윤혜진,Yun, Hye-Jin 한국특허정보원 2003 Patent 21 Vol.44 No.-

모 한방병원 응급실에 내원한 소아 환자에 대한 임상적 연구

윤혜진,백정한,서정민,Yun, Hye-Jin,Baek, Jung-Han,Seo, Jung-Min 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.2

Objectives The purpose of this study was to revitalize pediatric emergency care in oriental medical hospital. Methods The study was composed of 281 pediatric patients who visited emergency room of the ${\bigcirc}{\bigcirc}$ university oriental hospital, from March 2006 to February 2007. Results The age distribution showed that 1 to 3 year's patients(40.6%) are the most New pediatric patients(59.1%) were more than who received medical treatment in this place. The seasonal distribution of between month's section and the 24 solar terms's section made no differences and pediatric patients who visited in emergency room was most in spring, least in autumn. Moreover the changes of season's patients were more than others. Pediatric patients who visited during the weekends and holidays(50.9%) were more than during the weekdays(49.1%). Systemic division of the major problems were the digestive symptoms(44.5%) and nervous symptoms(30.6%), respiratory symptoms(12.5%), musculoskeletal symptoms(5.3%), dermatological symptoms(1.8%), cardiovascular symptoms(0.7%) and others(4.6%) followed. The time interval between arrival and onset : within 6 hours were the most(54.5%). Pediatric patients who had digestive, nervous, musculoskeletal diseases within 6 hours were the most, but in the case of patients who had respiratory diseases, most of them were visited within 48 hours. Acting and herb-med treatment(77.9%) were the most in medical treatments. Pediatric patients(69.0%) who didn't revisit in this hospital after treatment in emergency room were more than who revisited(29.9%). Conclusions Pediatric patients who visited in emergency room of oriental medical hospital were most not acute form of a serious diseases, patients most visited in disease prefer to oriental medicine; such as dyspepsia, convulsions, crying, ankle sprain. Further studies will be needed for the actual circumstance's reflecion from this hospital and other oriental hospitals nearby or other western emergency rooms for the accurate studies.

줄기세포 특허분석 보고서

윤혜진,Yun, Hye-Jin 한국특허정보원 2006 Patent 21 Vol.67 No.-

본 보고서는 한국, 일본, 미국, 유럽, 국제특허로 출원된 줄기세포분야 특허를 객관적이고 체계적인 방법으로 조사ㆍ분석하여 이를 통해 얻어진 분석결과를 국내 줄기세포 관련 연구자들 및 정책 입안자들에게 제공함으로써 특허마인드의 확산ㆍ특허와 연계된 연구방향 설정수립에 기여하며 국가적 차원의 정책수립을 위한 기초자료로 활용하기 위해 작성된 줄기세포 특허 분석 보고서로서 특허청의 용역사업으로 한국특허정보원이 수행하여 발간한 내용을 요약, 정리한 것이다.

의이인(薏苡仁)의 염증성 사이토카인 발현 및 조절에 관한 연구

윤혜진,이유진,강미선,백정한,Yun, Hye-Jin,Lee, Yu-Jin,Kang, Mi-Sun,Baek, Jung-Han 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.1

Objectives This study was evaluated the effects of CSE the regulatory mechanism of NO and cytokines in the LPS-stimulated Raw 264.7 cells. Methods The Coicis Semen MeOH extract dissolved in EMEM for 1 hour prior to the addition of LPS(1${mu}g/ml$). The cell viability was measured by MTT assay, and Nitric Oxide production was monitored by measuring the nitrite content in culture medium. The levels of cytokine and PGE2 were analyzed by sandwich immunoassays. Results CSE inhibited the production of NO (0.03 and 0.1 mg/ml), $TNF-{\alpha}$ (0.03 and 0.1 mg/ml), $IL-1{\beta}$ (0.03 and 0.1 mg/ml), IL-6 (0.03, 0.1 mg/ml) and PGE2(0.03 and 0.1 mg/ml) in Raw 264.7 cells activated with LPS(lipopolysaccharide). Conclusion According to the results above, Coicis Semen can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.

순환경제 실현을 위한 스마트패키지디자인의 지속가능성 분석과 활용

윤혜진,Yun, Hye-Jin (사)한국포장협회 2021 包裝界 Vol.336 No.-

수완부골의 X-ray 영상 및 종골의 초음파 영상에서 측정한 골연령을 통한 소아성장에 관한 임상연구

윤혜진,서정민,강미선,백정한,Yun, Hye-Jin,Seo, Jung-Min,Kang, Mi-Sun,Baek, Jung-Han 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.2

Objectives : The purpose of this study was to have better data and to make efficient clinical reviews about children's growth based on two methods; X-ray of hand, and ultrasound of calcaneus. Methods : The study was composed of 100 patients(50 of boys and 50 of girls) who visited in department of pediatrics, O O university oriental hospital considering growth and their development. Bone age was measured by the TW3 method's RUS score in simple X-ray image of hand and bone density through ultrasonic image of calcaneus. To predict children's estimated height, their parent's height, bone age, and present height's percentile was measured. Results and Conclusions : 1. The bone age results from X-ray image of hand and ultrasonic image of calcaneus were correlated. Younger children have older bone age from hand's X-ray than the one from calcaneus's ultrasound. Older children have older bone age from calcaneus's ultrasound than one from hand's X-ray. 2. Predicted adult height by bone age(BH) of hand's X-ray and BH of calcaneus's ultrasound were correlated, but predicted adult height by inheritance(IH) was not correlated with others. 3. Bone age and predicted adult height were correlated with age, height, weight, BMI, and especially with age and height. 4. Measuring bone age by X-ray image of hand and ultrasonic image of calcaneus was simple and effective way of estimating children's growth and development.

순환경제 실현을 위한 스마트패키지디자인의 지속가능성 분석과 활용

윤혜진,Yun, Hye-Jin (사)한국포장협회 2021 包裝界 Vol.336 No.-