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      • KCI등재

        접촉 유한요소모델을 이용한 미니 임플란트의 초기 응력분포 연구

        윤현주,정의원,이종석,김창성,김정문,조규성,김종관,최성호,Yoon, Hyun-Joo,Jung, Ui-Won,Lee, Jong-Suk,Kim, Chang-Sung,Kim, Jung-Moon,Cho, Kyoo-Sung,Kim, Chong-Kwan,Choi, Sung-Ho 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.4

        Mini implants had been used provisionally for the healing period of implants in the beginning. But it becomes used for the on-going purpose, because it is simple to use, economic and especially suitable for the overdenture. But there is few studies about the stability of mini implants, that is most important factor for the on-going purpose, and particularly the implant parameters affecting the initial stability. The purpose of this study was to evaluate the stress and the strain distribution pattern of immediate-loaded screw type orthodontic mini-implant and the parameters affecting the initial stability of immediate-loaded mini-implant. Two dimensional finite element models were made and contact non-linear finite element analysis was performed. The magnitude and distribution of Von Mises stresses were evaluated. The obtained results were as follows: 1. The stress was concentrated on the thread tip of an implant in the cortical bone. 2. The direction of load is the most important factor for the stress distribution in cortical bone. 3. The diameter of an implant is the most important factor for the stress distribution in the trabecular bone. In conclusion, if the horizontal load vector is successfully controlled, mini-implants, which diameter is under 3mm, can be used for the on-going purpose.

      • 정신분석과 초기불교의 관점에서 보는 자아

        윤현주(Yoon, Hyun-Joo) 한국불교상담학회 2018 불교상담학연구 Vol.11 No.-

        본고는 정신분석에서의 자아와 불교에서 보는 자아관을 비교하여 양자 간의 유사성을 고찰하고자 한다. ‘나’ 혹은 ‘자아’라는 개념은 타인과 구별되는 한 인간의 개인성, 독립성, 고유성 등을 그 속성으로 한다. 서양심리학, 특히 서양의 심리치료 이론은 이러한 ‘나’ 혹은 ‘자아’ 개념에 토대를 두고 있다. 이에 반해 불교의 가르침에 따르면 일체의 유위법은 고정된 실체가 없고 자아 또한 그러하다. 무아 사상이 불교의 중요한 교리이긴 하지만 초기불교에도 자아에 해당하는 용어가 있으며 자아 개념이 형성되어지는 과정에 대한 탐구도 있다. 정신분석에서 자아는 후대로 내려올수록 점차 기능적이고 관계적인 측면이 강조되고 있다. 초기불교에서는 아뜨만 사상과 구별되는 자아의 비실체성, 기능성, 연기성 등을 설하고 있다. 본고는 이런 측면에 중점을 두고 정신분석과 초기불교에서 보는 자아관에 유사성이 있음을 드러낸다. This essay examines the theory of psychoanalysis, which emphasizes the self, and the insight of Buddhist psychology, which emphasizes the no-self, and how they can communicate with each other in a similar perspective. Although no-self is an important doctrine of Buddhism, early Buddhism also has a term that corresponds to the self, and there is also a quest for the process of forming the concept of self. Therefore, in this study, I examined the self of psychoanalysis and early Buddhism with a focus on the similarity.

      • KCI등재

        퉁퉁마디 탈염을 통한 식품품질 및 기능성 향상

        윤현주(Hyun Joo Yoon),조은아(Eun-Ah Cho),박선영(Seon Yeong Park),권미향(Mee-Hyang Kweon) 한국식품영양과학회 2017 한국식품영양과학회지 Vol.46 No.12

        온도 변화에 따른 물에 대한 염류의 용해도 차이를 이용하여 퉁퉁마디 내 염분 제거를 통해 기능성 식품 소재나 식품 가공품의 원료로서 활용가치를 높이고자 하였다. 퉁퉁마디의 탈염에 적합한 건조방법을 찾고, 가용성 유기물 성분의 용출은 최소화하고 나트륨염의 용출을 최대로 하는 탈염조건을 통해 품질특성을 비교하였다. 동결건조와 열처리 후 열풍건조 두 가지 방법을 이용하여 퉁퉁마디를 건조한 결과 색도에서는 큰 차이가 없었지만, 물에 대한 염류의 용해도에 있어 동결건조 방법이 탈염에 더 적합한 것으로 판단되었다. 물의 온도, 탈염시간을 조절하여 퉁퉁마디 동결건조 분말의 탈염을 실시한 결과, 총 고형분과 총 염분 함량을 고려하였을때 4°C 이하의 냉수로 3분 추출하는 것이 바람직하다고 판단되었다. 이러한 탈염 조건으로 횟수에 따른 비교를 실시한 결과 1번의 탈염으로 상당량의 염이 용출되었고, 염도 대비 가용성 고형분의 비율(Brix/salinity)은 3번 탈염한 것이 1.44로 가장 낮았다. 색도는 탈염 후 L*, a* 값은 낮아지고 b*값은 증가하였으며, 횟수가 증가할수록 그 차이가 조금씩 증가하였다. 나트륨 함량은 탈염 전 14.71%에서 3번의 탈염으로 0.36%로 줄어들었다. 3번 탈염한 퉁퉁마디 분말의 영양성분 분석 결과 탄수화물이 크게 증가하였고, 나트륨 함량이 줄어들면서 일부 다른 미네랄 성분이 증가하였다. 또한, 생리활성 물질인 폴리페놀, 플라보노이드, 클로로필의 함량이 각각 11.8 mg/g, 5.8 mg/g, 54.25 mg/g으로 탈염 전보다 거의 2배 가까이 증가하였다. 또한, 퉁퉁마디 탈염분말의 추출물에 대한 기능성을 평가한 결과 항산화, 항고혈압 및 항당뇨 활성이 탈염 전의 추출물보다 현저히 증가함을 확인할 수 있었다. 퉁퉁마디 탈염에 적합한 건조방법과 온도에 따른 물에 대한 염류의 용해도 차이를 이용한 탈염조건의 설정을 통해 나트륨 함량은 감소하고, 다른 미네랄 성분과 탄수화물, 유용생리활성 물질은 증가한 퉁퉁마디 탈염 분말을 확인할 수 있었다. 이러한 결과를 바탕으로 퉁퉁마디 탈염분말은 일반 식품소재뿐만 아니라 나트륨 함량은 낮고 칼륨 등의 유용 미네랄과 염생식물 고유의 영양성분 및 생리활성물질의 함량은 높아진 새로운 기능성 강화 소재로서 활용 가치가 크다고 하겠다. Salicornia europaea (SE) has recently emerged as a food material and physiologically effective halophyte cultivated by using sea water irrigation without any fertilizers or pesticides. However, SE powder has limited usability in processed and functional foods due to its high salt content (35∼40%). The purpose of this study was to increase the utilization of SE powder as a functional food material by removing only sodium salt (NaCl) from SE without loss of useful minerals such as potassium, calcium, and iron, nutrients such as carbohydrates and proteins, and useful physiologically active substances such as chlorophylls, polyphenols, and flavonoids. This research resulted in the development of a desalination method based on differences in water solubility of salts with changes in temperature. Considering the color value and solubility of sodium salt in water, freeze drying method was suitable for desalting of SE. When SE powder was extracted with stirring in cold water at low temperature (4°C), as compared with room-temperature water and hot water, useful minerals excluding sodium salt and organic soluble components were eluted at remarkably low levels while there was no large difference in the elution degree of sodium salt. The sodium content of SE powder (14.71%) decreased to 0.36% after three desalting procedures. As the number of desalting procedures increase, a* value of color gradually decreased while the ratio of Brix and salinity also gradually decreased. In addition, compared with before desalination, desalted powder remarkably increased the contents of dietary fiber as well as polyphenols, flavonoids, and chlorophylls. Moreover, compared with before desalination desalted SE powder, remarkably improved anti-oxidant, anti-hypertensive, and anti-diabetic activities. Thus, functionally reinforced desalted SE is suggested as a functional and processed food materials.

      • KCI등재
      • KCI등재

        님추출물의 경구투여에 따른 랫드의 신장독성 연구

        윤현주 ( Hyun Joo Yoon ),최미선 ( Mi Seon Choe ),조현조 ( Hyeon Jo Cho ),한범석 ( Beom Seok Han ),박경훈 ( Kyung Hun Park ),오진아 ( Jin Ah Oh ),조남준 ( Nam Jun Cho ),백민경 ( Min Kyoung Paik ) 한국환경농학회 2014 한국환경농학회지 Vol.33 No.2

        BACKGROUND: Azadirachta indica has been widely used as environment-friendly organic materials because of its insecticidal properties. This study was carried out to investigate the acute toxicity and the subacute toxicity of Azadirachta indica extract(AIE) in rats. METHODS AND RESULTS: For the oral acute toxicity test, Sprague-Dawley rats were gavaged with 2.0 g/Kg bw of AIE. The LD50 value was greater than 2.0 g/Kg bw for both male and female rats. For the subacute toxicity study, rats were treated with AIE at doses of 0.5, 1.0, 2.0 mg/Kg bw once a day for 4 weeks(n=10 animals per each group). There were no significant changes in body weight, food intake and water consumption observed during the experimental duration. In addition, no difference of relative kidney weight was observed among all treated groups. Serum creatinine level in the AIE 2.0 g/Kg group increased significantly compared with that of control group in male rats, but serum blood urea nitrogen was significantly decreased in a dose-dependent manner (P<0.05). Significant increase of serum cholesterol levels were observed in all AIE groups, compared with the control group, in the female rats (P<0.05). However, histopathological examination of the kidney did not reveal any significant lesions in all groups. CONCLUSION: On the basis of results, it could be concluded that oral administration AIE didn`t cause any toxic response in kidney, except the increased serum cholesterol.

      • KCI등재

        라이프스타일에 따른 디자인 호텔 로비 디자인의 연상 기제에 관한 연구

        윤현주(Yoon Hyun-Joo),류호창(Lyu Ho-Chang) 한국실내디자인학회 2016 한국실내디자인학회논문집 Vol.25 No.6

        In modern society which changes from quantity-seeking society to value-seeking one, people’s various lifestyles have great effect on consumption patterns and work as an important factor in choosing hotels. The fact that design hotels, which provide unique experiences with differentiated and sensitive designs by reflecting various lifestyles, recently attract attention can be understood in the same context. As a matter of fact, design hotels recently serve as destinations as they become cultural and artistic icons which reflect customer lifestyles. Especially, the designs of lobby spaces in hotels play deciding role in customers’ choices while representing the nature of hotels. In this respect, under the premise that the kinds of accumulated experiences are different depending on lifestyles and preferences for specific interior spaces are influenced by association mechanism formed by experiences, this study analyzed lobby spaces of design hotels which focus on specific lifestyles from the perspective of association mechanism based on experiences. As the method of analysis, this study classified the types of lifestyles and conducted case analysis to investigate what association mechanism works to enhance the preference of design hotels by types. Study classified lifestyles into experiential activity type, social meeting type, fashion-pursuing type and hideout-preferring type and analyzed cases of lobby designs in design hotels. The results of this case analysis are as follows; First, experiential activity type mainly utilized quasi-association and approach association through senses and social meeting type utilized quasi-association and memory association through emotions while fashion-pursuing type utilized quasi-association and presumption association through intuition and hideout-preferring type utilized quasi-association and approach association through thoughts. Second, it was found that most lobby designs are characterized by association mechanism in visual·formative nature and that in temporal·spatial nature working in complex way, and, through such process of association expansion, space stories are created. Stories of spaces created this way become unique identities of design hotels that provide new experiences for customers.

      • KCI등재

        님추출물의 in vitro 항돌연변이원성 및 유전독성 영향

        윤현주 ( Hyun Joo Yoon ),조현조 ( Hyeon Jo Cho ),김진효 ( Jin Hyo Kim ),박경훈 ( Kyung Hun Park ),길근환 ( Geun Hwan Gil ),오진아 ( Jin Ah Oh ),조남준 ( Nam Jun Cho ),백민경 ( Min Kyoung Paik ) 한국응용생명화학회(구 한국농화학회) 2014 Journal of Applied Biological Chemistry (J. Appl. Vol.57 No.3

        님 추출물은 포유류에 낮은 독성을 가지고 있기 때문에 유기농업자재로 주로 이용되고 있다. 그러나 님 추출물은 림프구의 염색체 이상을 야기한다는 연구결과가 보고되었다. 따라서, 본 연구는 님 추출물을 이용하여 항돌연변이원성 시험 및 유전독성을 평가하였다. 항돌연변이원성 시험은 복귀돌연변이 시험을 이용하여 시험하였다. 복귀돌연변이 시험은 2개의 님 추출물을 Salmonella Typhimurium 5개 균주를 이용하여 돌연변이 유발 가능성을 평가하였다. 복귀돌연변이시험과 염색체이상시험은은 대사활성계 처리군(S-9 mix)과 대사활성계 미처리군(PBS)으로 나누어 양성대조군과 음성대조군을 사용하여 실시하였다. 염색체이상시험은 Chinese hamster lung cell을 이용하여 님추출물 시료에 대사활성계 처리군은 6시간 노출시켰고, 대사활성계 미처리군은 각각 6시간과 24시간 노출시켜 시험하였고, 음성대조군과 양성대조군을 사용하였다. 4 NQO에의해 유도 된 돌연변이 집락수는 님추출물 시료 처리에 의해감소되어 SRE는 항 돌연변이 효과가 있을 수 있음을 나타냈다. 복귀돌연변이와 염색체이상시험은 님추출물 모든 시험 농도군에서 대화활성계의 처리 유무와 관계없이 음성으로 판정되었다. 이상의 결과를 ICH에서 제안된 유전독성 batterysystem에 근거해 살펴 봤을 때 본 연구에서 사용된 님 추출물2종은 모두 유전독성이 없어 안전함을 확인 할 수 있었다. Azadirachta indica extract (AIE) has been regarded asa promising source of environment-friendly organic materialsowing to their low mammalian toxicity. However, quite a bit ofresearch has been reported that AIE may cause clastogens inhuman lymphocytes. Therefore, this study was conducted toevaluate the antimutagenic and genotoxicity of two samples ofAIE. Antimutagenic test was experimented by using bacterialreverse mutation test. In the bacterial reverse mutation test, fivestrains Salmonella Typhimurim of two samples of AIE in order toevaluate its mutagenic potential. Bacterial reverse mutation testwas also performed on positive control and negative controlgroups in the presence of the metabolic activation system (S-9mix) and metabolic non-activation system. In the chromosomeaberration test, Chinese hamster lung cells were exposed to AIEfor 6 or 24 h with BPS, or for 6 h with S-9 mix. Negative andpositive control groups were experimented for chromosomeaberration test. As a result, the number of mutated coloniesinduced by 4-NQO were reduced by AIE treatment in all strains, indicating that AIE may have antimutagenic effects. Bacterialreverse mutation and chromosomal aberration were not shown atall concentration of AIE, regardless of activation of the metabolicsystem. we concluded that two AIE samples used in this studyhave no genotoxic effects to human, according to the genotoxicitybattery system suggested by ICH (International Conference onHarmonization).

      • KCI등재
      • KCI등재

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