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윤태경(Tae-Kyung Yoon),김동준(Dong-Joon Kim) 한국해양공학회 1997 韓國海洋工學會誌 Vol.11 No.2
This paper describes the automatic mesh generation on the ship hull surface. At first, ship hull is defined as a collocation of composite surface patches which satisfy the geometric continuity between adjoining patches by using Gregory surface patch method. Node points that would be mesh points are generated by considering the surface curvature. The triangulation of the node points is done by the combination of Ohtsubo’s method and Choi's one. After triangulation, shape improvement and quadrilateralization is done with specific criterion. An application to the actual ship and the results are shown.
전기투석에 의한 암모니아성질소의 제거 시 운전인자의 영향
윤태경(Tae-kyung Yoon),이강춘(Gang-choon Lee),정병길(Byung-gil Jung),한영립(Young-rip Han),성낙창(Nak-chang Sung) 한국청정기술학회 2011 청정기술 Vol.17 No.4
고농도의 암모니아성질소를 함유하는 폐수의 처리에 전기투석공정의 적용성이 실험적으로 평가되었다. 처리 성능은 전기 투석공정의 운전인자 중 유입농도, 운전전압, 그리고 유속이 암모니아성질소의 제거효율에 미치는 영향으로 측정되었다. 한계전류밀도는 유입농도와 유입유속이 증가함에 따라 선형적으로 증가하였고, 유입농도에 따라 목표농도에 도달하는 시간은 직선적인 비례관계를 보였다. 상대적으로 큰 암모니아성질소의 이온당량전도도와 이온이동도로 인하여 유입유속의 증가는 제거속도를 지속적으로 증가시켰다. 또한 운전전압의 증가에 따라 제거속도는 증가하였다. 본 연구에 사용된 전기투석모듈에서 고농도의 암모니아성질소를 제거하는 운전조건으로 유입유속은 3.2 L/min, 운전전압은 한계전류밀도에 해당하는 전압의 80~90%가 추천된다. To evaluate the feasibility of electrodialysis for ammonia nitrogen removal from wastewater, the effects of operating parameters such as diluate concentration, applied voltage and flow rate on the removal of ammonia nitrogen were experimentally estimated. The removal rate was evaluated by measuring the elapsed time for ammonia nitrogen concentration of diluate to reach 20 mg/L. Limiting current density (LCD) linearly increased with ammonia nitrogen concentration and flow rate. The elapsed time was linearly proportional to initial concentration of diluate. Due to relatively large equivalent ion conductivity and ion mobility of ammonia nitrogen, the removal rate increased consistently with flow rate. Increase in the applied voltage gave positive effect to removal rate. From the operation of the electrodialysis module used in this research, the flow rate of 3.2 L/min and 80~90% of applied voltage for LCD are recommended as the optimum operating condition for the removal from high concentrate ammonia nitrogen solution.
마늘 열수 추출물의 활성산소종 생성을 통한 인체백혈병세포의 apoptosis 유발
최우영(Woo Young Choi),정경태(Kyung Tae Chung),윤태경(Tae Kyung Yoon),최병태(Byung Tae Choi),이용태(Yong Tae Lee),이원호(Won Ho Lee),류충호(Chung Ho Ryu),최영현(Yung Hyun Choi) 한국생명과학회 2007 생명과학회지 Vol.17 No.12
본 연구에서는 몇 가지 암세포를 대상으로 마늘 열수추출물(WEAS)의 항암활성을 조사하였으며, 비교적 높은 감수성을 보인 백혈병세포를 대상으로 세포증식억제가 apoptosis 유도와 연관성이 있음을 제시하였다. WEAS에 의한 U937 세포의 apoptosis 유도는 세포주기 G2/M arrest와 연관성이 있었으며, 다양한 apoptosis 조절 유전자들의 발현 변화를 동반하였음을 확인하였다. 이러한 apoptosis 조절 인자들의 발현변화는 미토콘드리아 막 전위의 소실과 연관성이 있었으며, WEAS에 의한 암세포의 G2/M arrest에 의한 apoptosis 유발에 ROS가 중요한 조절자로 작용함을 알 수 있었다. The health benefits of garlic (Allium sativum L.) are derived from a wide variety of components and from the different ways it is administered. The known health benefits of garlic include cardiovascular protective effects, stimulation of immune function, reduction of blood glucose level, protection against microbial, viral and fungal infections, as well as anticancer effects. In the present study, it was examined the effects of water extract of A. sativum (WEAS) on the growth of cultured human tumor cells in order to investigate its anti-proliferative mechanism. Treatment of WEAS to tumor cells resulted in the growth inhibition, especially in leukemia cells, which was associated with induction of G2/M arrest of the cell cycle and apoptosis. In order to further explore the critical events leading to apoptosis in WEAS-treated U937 human leukemia cells, the following effects of WEAS on components of the mitochondrial apoptotic pathway were examined: generation of reactive oxygen species (ROS), alteration of the mitochondrial membrane potential (MMP), and the expression changes of Bcl-2 and IAP family proteins. The cytotoxic effect of WEAS was mediated by its induction of apoptosis as characterized by the occurrence of DNA ladders, apoptotic bodies and chromosome condensation in U937 cells. The WEAS-induced apoptosis in U937 cells was correlated with the generation of intracellular ROS, collapse of MMP, activation of caspase-3 and down-regulation of anti-apoptotic proteins. The quenching of ROS generation with antioxidant N-acetyl-L-cysteine conferred significant protectionagainst WEAS-elicited ROS generation, caspase-3 activation, G2/M arrest and apoptosis. In conclusion,the present study reveals that the cellular ROS generation plays a pivotal role in the initiation of WEAS-triggered apoptotic death in U937 cells.
중격피부 피판과 석고붕대 고정을 이용한 하지 교차 피판술
최수중,윤태경,이영호,이응주,장호근,장준동,Choi, Soo-Joong,Yoon, Tae-Kyung,Lee, Young-Ho,Lee, Eung-Joo,Chang, Ho-Guen,Chang, Jun-Dong 대한미세수술학회 1998 Archives of reconstructive microsurgery Vol.7 No.2
Large soft tissue defect of the ankle and foot can present a difficult reconstructive problem to the surgeon. Local musculocutaneous, local fasciocutaneous or free flap is usually the first choice for providing soft tissue coverage. However, in certain situations, local flaps from the same leg and free flap may not be suitable. These include extensive soft tissue injury, where no suitable recipient vessels can be found, previous local fasciocutaneous flap or free flap failure. In such cases, we have utilized the septocutaneous(fasciocutaneous) branch flap of posterior tibial artery from the opposite healthy limb. We present 5 cases of cross leg flaps, which have been modernized with current understanding of vascular anatomy and current fixation technology. All cross leg flaps were based on the axial blood supply of the fasciocutanous branch of the posterior tibial artery. Cross-clamping with bowel clamp was used to create intermittent periods of ischemia. Adjacent lower extremity joints were exercised during the periods of attachment. The results have been quite encouraging. We conclude that the cross leg flap using septocutaneous flap and cast immobilization can be successfully and expeditiously used to cover defects of the ante and foot.