정신분열병 환자의 인지 기능 재활에 대한 보드게임 요법의 효과 분석

윤탁,정안순,Youn, Tak,Jeong, An-Soon 대한생물정신의학회 2006 생물정신의학 Vol.13 No.2

Objectives : In order to explore effects of board-game therapy for cognitive rehabilitation in patients with schizophrenia, we investigated the change of executive cognitive function over a 2-month period of board-game therapy in patients with schizophrenia. Methods : Two groups of chronic schizophrenic inpatients were participated in this study. One group(n=21) were treated with board-game therapy for 2 months and the other control group(n=19) were not treated. For the evaluation of the executive cognitive function, a Wisconsin Card Sorting Test(WCST) was administered before and after the introduction of the board-game therapy. PANSS score change was also evaluated. Result : At the beginning of this study, there was no significant difference in performance of cognitive function tests, demographical data or clinical severity between both patient groups. After 2 months of treatment with the board-game therapy, the board-game therapy group showed significant improvements of executive cognitive function without any significant change of their schizophrenic symptoms. On the contrary, there was no change in control group. Conclusion : This study showed that a board-game therapy is effective for the enhancement of executive cognitive function in patients with chronic schizophrenia. A board-game therapy could be introduced with ease into psychiatric fields, such as inpatients' or outpatients' clinic wards and day hospital. Our result indicates that the board-game therapy is a promising tool for the enhancement of cognitive function, especially executive cognitive function and helpful for cognitive rehabilitation for schizophrenic patients.

폐쇄성 수면무호흡증에서 지속적 상기도 양압술 시행이 교감신경계 활성도에 끼치는 영향 : 심전도 스펙트럼 분석

윤탁,박해정,김의중,정도언,Youn, Tak,Park, Hae-Jeong,Kim, Eui-Joong,Jeong, Do-Un 대한수면의학회 2000 수면·정신생리 Vol.7 No.1

Objectives: Obstructive sleep apnea syndrome(OSAS) is known to be associated with the changes of autonomic nervous system (ANS). Nasal continuous positive airway pressure(nCPAP) treatment was found to correct abnormal ANS changes in OSAS but it remains to be further clarified. We aimed to assess the effects of nCPAP on ANS manifested on electrocardiogram, using spectrum analysis in the subjects with OSAS. Methods: Digital polysomnography was performed in 18 patients with OSAS(mean age $43.7{\pm}16.6$ years ; 17 males, 1 female ; mean respiratory disturbance index (RDI) $48.6{\pm}20.9$) for one baseline and another CPAP nights. From each night, 300 continuous beats of ECGs without artifact were chosen from both stage 2 sleep and REM sleep and they were used for power spectrum analysis. We compared between baseline and CPAP nights the heart rate variability including VLF(very low frequency power), LF (low frequency power), HF(high frequency power), R-R means, R-R variance, and LF/HF ratio, using Wilcoxon signed ranks test. Results: In all patients, nCPAP proved to be effective in relieving apneas and snoring. During nCPAP night compared with baseline night, decreases in VLF(p<0.05), LF(p<0.01), and R-R variance(p<0.05) were found in stage 2 sleep, and decreased LF(p<0.05) was found in REM sleep. No significant differences in each sleep stage were found in other variables between the two nights. Conclusion: Our findings suggest that OSAS increases the activity of sympathetic nervous system and nCPAP application effectively decreases the activity. And nCPAP does not appear to influence the parasympathetic nervous activity in OSAS.

21 세기 한국사회 전망 / [ 경제분야 ] 21 세기 거시경제분야의 전망

윤탁 한국행정연구원 2000 한국행정연구 Vol.9 No.1

N/A

권두언

윤탁 대한지방행정공제회 1973 地方行政 Vol.22 No.240

N/A

갑상선 분화암에 대한 방사성요오드치료 후 발생한 급성 림프구성 백혈병 1예

윤탁,김대영,이근욱,김대희,윤성수,박선양,김병국 대한내과학회 2004 대한내과학회지 Vol.66 No.4

고형암의 치료와 관련되어 발생하는 이차백혈병의 예후는 불량한 것으로 알려져 있다. 저자들은 갑상선 유두암으로 진단 후 900 mCi의 방사성 요오드치료를 받은 환자에게 발생한 급성 림프구성 백혈병으로 동종조혈모세포이식을 시행하고 완전 관해 중인 환자 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. During the last decade the issue of therapy-related myelodysplasia (t-MDS) and acute myeloid leukemia (t-AML) following high-dose chemotherapy (HD-CT) and autologous stem cell transplantation (ASCT) or conventional chemotherapy, radiotherapy for malignant diseases has become increasingly important. The number of patients with hematologic malignancies and chemosensitive or radiosensitive solid tumors undergoing this new type of treatment has expanded dramatically. Recently, we experienced a case of 35-tear-old female patient with therapy-related acute lympho-blastic leukemia (t-ALL) after ^(131)I treatment for thyroid papillary carcinoma. Total ^(131)I dose the patient received was 900mCi and patient was diagnosed as having ALL 11 months after last ^(131)I treatment. Although the prognosis of therapy-related acute leukemia/myelodysplastic syndrome is poor, the patient is alive in complete remission after allogeneic bone marrow transplantation from HLA-matched sibling donor. Given the rarity of this case, we report the case with literature reviews.

포스터 전시 발표 : 혈액종양,감염 ; 진행성 대장암에서 Oxaliplatin, 5-Fluorouracil 급속정주, Leucovorin 급속정주를 이용한 외래 투여일정 복합화학요법의 효과에 대한 연구

윤탁,김대영,이근욱,김상일,박숙련,백지연,최인실,김동완,김태유,허대석,방영주,김노경 대한내과학회 2003 대한내과학회 추계학술대회 Vol.65 No.10

구연 : 혈액종양 ; 최근 2년간 시행한 저용량 전처치 동종 조혈모세포이식의 성적

윤탁,이근욱,김대영,김인호,윤성수,박선양,김병국,김노경 대한내과학회 2002 대한내과학회 추계학술대회 Vol.63 No.-

전기경련치료의 마취를 위한 실제적 문제들

윤탁,김용식,이남영,김세현,최준권,이정혁,정인원,Youn, Tak,Kim, Yong Sik,Lee, Nam Young,Kim, Se Hyun,Choi, Jun Gwon,Lee, Jeoung Hyuk,Chung, In Won 대한생물정신의학회 2017 생물정신의학 Vol.24 No.3

Electroconvulsive therapy (ECT) has been recognized effective as primary or secondary treatments for major psychiatric disorders including depression and schizophrenia, as well as psychiatric emergency such as suicide, food refusal and catatonia, and so on. Medicines used in anesthetic induction for ECT, cause various reactions in autonomous, hemodynamic, and neuromuscular systems. The anesthetics also affect the duration, threshold, and intensity of seizures evoked with electric stimuli, and thus modify the seizure quality in ECT. Individual characteristics of age, sex, weight, comorbid physical disorders, and medications should also be considered for optimal clinical response after ECT. When preparing for anesthesia, adequate anesthetic agents and muscle relaxants, and rapid recovery should be carefully considered. We conducted a case-series study to address practical issues that are frequently encountered during ECT anesthesia with reviews of updated journals in order to provide practical helps to clinicians who are preparing ECT for their patients.

노인에서의 사건수면

윤탁,정도언,Youn, Tak,Jeong, Do-Un 대한수면의학회 2001 수면·정신생리 Vol.8 No.1

The change of sleep pattern is one of the most often altered normal physiological functions in elderly people. Besides normal change of sleep, insomnia and sleep apnea syndrome (SAS) are (one of) the main complaints. In addition, parasomnia is also frequent in this age group. Several parasomnias frequently found in the elderly are reviewed. Periodic limb movements in sleep (PLMS), restless legs syndrome (RLS), and REM sleep behavior disorder are the most frequent parasomnias in old age. Most parasomnias could be diagnosed by polysomnography, and be treated easily. Therefore, early and precise diagnosis and management for parasomnia in aging people are needed.

강박 장애의 정량화 뇌파 소견

윤탁,권준수,조맹제,김용식,이부영,Youn, Tak,Kwon, Jun Soo,Cho, Maeng-Je,Kim, Yong Sik,Rhi, Bou-Yong 대한생물정신의학회 1996 생물정신의학 Vol.3 No.2

The quantitative EEGs of obsessive-compulsive disorder patients were analyzed using spectral analysis and compared to age and sex-matched controls. The subjects were 19 patients(men=15, women=4) suffering from obsessive-compulsive disorder(DSM-III-R). Absolute power, relative power and interhemispheric asymmetry of EEG were used to compare obsessive-compulsive disorder patients with controls. In order to fit the EEG data to a normal distribution, a log transformation of power values of every bandwidth in each deviation was calculated prior statistical analysis. The Wilcoxon rank test was performed to compare obsessive-compulsive group to the control group. In obsessive-compulsive disorder, abnormalities of quantitative EEGs are prominent in fronto-central. These results ore compatible with other brain imaging studies of obsessive-compulsive disorder and suggested that fronto-central area plays an important role in the pathophysiology of obsessive-compulsive disorder.