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윤진호 한국기상학회 2021 한국기상학회 학술대회 논문집 Vol.2021 No.10
2015년 파리기후협약에 따르면 지구평균기온을 산업혁명이전 대비 2.0도 궁극적으로 1.5도 상승에서 막아보려는 노력을 하기로 하였으며 이에 따라 다양한 연구결과들이 도출되었다. 하지만, 산불위험도의 변화에 대해서는 상대적으로 많은 연구가 진행되지 않았다. 본 연구에서는 최근 발생하고 있는 대형, 초대형 산불의 가능성을 높이는 조건들과 이러한 조건들의 변화 양상을 조사하였다. 특히, 산불은 온도, 강수량의 조건에 민감하게 반응하며 미래에 발생하는 가뭄의 조건들과 밀접한 연관을 가지고 있다. 본 연구에서는 1.5도, 2.0도의 0.5도 차이에도 산불발생위험도, 특히 대형산불 발생위험도의 차이는 명확하게 존재하고 있음을 보였다. 물론, 좀 더 정교한 모델링 기법을 통한 추가 연구가 필요하지만 지구온난화를 1.5도로 막는 다면 커다란 위험요소를 제거 할 수 있음을 보여주고 있다.
분열효모 Schizosaccharomyces pombe에서 spThp1 유전자 결실돌연변이의 제조와 특성 조사
윤진호,Yoon Jin-Ho 한국미생물학회 2006 미생물학회지 Vol.42 No.2
분열효모인 Schizosaccharomyces pombe에서 mRNA의 핵에서 세포질로의 이동에 관여할 것으로 여겨지는 spThp1 유전자의 결실돌연변이주(deletion mutant)를 제조하여 그 특성을 조사하였다. 이배체(diploid) 균주의 한 spThp1 유전자를 결실시킨 후 4분체분석(tetrad analysis)을 수행한 결과, 이 유전자는 생장에 필수적이지 않았다. 또한 결실돌연변이주는 mRNA 수송도 큰 결함을 보이지 않았다. 하지만 spThp1 는 mRNA의 운반체를 암호화하고 있는 spMex67와 합성치사(synthetic lethality)를 보였다. 이 결과는 분열효모의 spThpl도 mRNA의 핵에서 세포질로의 이동에 역할을 하고 있음을 암시한다. The sp%pl null mutant was constructed to study the function of fission yeast Schizosaccharomyces pombe spThp1, which is homologous to budding yeast Saccharomyces cerevisiae THP1. Tetrad analysis showed that the spThp1 is not essential for vegetative growth. The spThp1 null mutant also showed no massive poly(A)+ RNA export defect. However, spThp1 null is genetically associated with spMex67 null. These results suggest that spThp1 is involved in mRNA export out of the nucleus.
미세 문합술에 있어서 9-0 PDS 와 9-0 Ethilon 사용에 대한 비교연구
윤진호 梨花女子大學校 醫科大學 醫科學硏究所 1991 EMJ (Ewha medical journal) Vol.14 No.4
The search for a superior absorbable surgical suture has been underway for years. The synthetic materials have been shown to have certain advantages over the use of the familiar natural absorbable gut sutures. Specially, since synthtic absorbable sutures are degraded by simple hydrosis rather than by phagocytosis. they elicit a minimal tissue reaction. A newly-developed absorbable monofilament, poly-dioxanone(PDS, Ethicon) has certain adventages : it passes easily through tissues retains its tensile strength for a long time, and produces minimal tissue reaction. 9-0 absorbable polydioxanone(PDS) has been compared to 9-0 nonabsorbable Ethilon in order to evaluate any advantages of either suture in microvascular surgery. In each of 45 rats, one femoral artery was anastomosed end-to-end with PDS and the other with Ethilon. Specimen were harvested 48hr. 14day and two months post operatively. Histologic analysis of inflammation, fibrosis, and medial necrosis of the anastomoses revealed no significant differences between the two materials. There was no difference as regards stenosis and aneurysm formation, when evaluated independently by the two methods. It can be concluded that the amount of inflammation and fibrosis leading to stenosis is related to the amount of trauma at the time of surgery and not to the type of suturing material used.
Fibrin Glue를 이용한 미세 혈관문합술에 대한 실험적 연구
윤진호,김한중 梨花女子大學校 醫科大學 醫科學硏究所 1988 EMJ (Ewha medical journal) Vol.11 No.1
Since the anastomosis by suture most widely used in microvascular surgery has two major disadvantage in that it may inflict considerable damage on the vessel ends and that the suture material may function as a thrombogenic agent, much effort has been spent in developing methods of anastomosis in which the number of sutures is reduced to minimum. As one of such efforts, we performed the following experiment using only fibrin glue without leaving out any suture material. First, we divided the femoral artery of the rats and telescoped the proximal end into the distal end by traction of two U-shaped guide sutures. Next, we removed the the guide sutures and dropped he fibrinogen and the thrombin solution ddissolved in the distilled water and calcium chloride respectively on the telescoped area. After waiting for 5 minutes, vascular clamps were released. The results we got from the gross and histological examination showed that this method has advantage as follows; 1) This method is easier and speedier than suture technique. 2) Suture material was not exposed into the lumen. 3) There was less vessel trauma owing to fewer sutures and less manipulation of the vessel end. 4) Blood leakage from the anastomosal site was prevented. 5) There was no aneurysm.