국내 신호망에서의 다중신호점 기능 수용

윤종철(Jong-Chul Youn),양형열(Hyung-Yeul Yang) 대한전자공학회 1998 대한전자공학회 학술대회 Vol.1998 No.11

한국판 치매 행동평가 척도(BRSD-K)와 한국판 Neuropsychiartic Inventory(NPI-K)의 도구적 특성 비교

윤종철 ( Jong Chul Youn ),이원혜 ( Won Hea Lee ),최종배 ( Jong Bae Choi ) 한국정신병리진단분류학회 2008 精神病理學 Vol.17 No.1

Aim: This study was purposed to compare the psychometric properties between the Korean version of Behavior Rating Scale for Dementia(BRSD-K) and Neuropsychiatric Inventory(NPI-K). Methods: The formal caregivers of 99 dementia patients who were diagnosed by DSM-IV criteria and admitted to geriatric hospital or nursing home were interviewed by both BRSD-K and NPI-K for measuring behavioral and psychological symptoms in dementia (BPSD). Overall prevalence of BPSD, mean scores of BRSD-K and NPI-K according to the severity of dementia, correlations between BRSDK total and subscale scores and the corresponding scores of NPI-K were analyzed. Results: Above 95% of the subjects showed one or more BPSD during the last month. Severity of BPSD measured by BRSD-K and NPI-K were not statistically significant among the severity of dementia. Correlations between BRSD-K subscale score and the corresponding scores of NPI-K were statistically significant except that of psychotic subscale score of BRSD-K and delusion score of NPI-K(p<0.01). Conclusion: Results of this study showed that BRSD-K and NPI-K were not identical although both were useful to evaluate BPSD. It was also suggested that BPSD of inpatient were different from those of outpatient since it was relatively severe in mild stage.

노인의 주관적 기억문제 호소와 객관적 인지기능 저하의 연관성

윤종철 ( Jong Chul Youn ) 한국정신병리진단분류학회 2003 精神病理學 Vol.12 No.1

노인병원 입원 노인의 낙상 예측모델 개발연구

윤종철 ( Jong Chul Youn ),정찬승 ( Chan Seung Chung ),신동선 ( Dong Sun Shin ),이소애 ( So Ae Lee ),신정심 ( Jung Sim Shin ) 한국정신병리진단분류학회 2012 精神病理學 Vol.21 No.1

Objectives:This study aimed to identify clinical risk factor of fall and develop brief new fall risk assessment tool for long term geriatric hospital. Methods:Total 167 inpatients including 133 dementia patients were recruited from three ward and baseline clinical characteristics were assessed based on medical chart and direct observation of registered nurses. Any fall event including near fall and not observed fall were recorded during six months. Associations between fall and baseline risk factors were analyzed using univariate analysis and then multiple logistic regression analysis. After constructing new scale, validity was evaluated using ROC curve analysis and AUC value was compared to Morse fall scale and STRATIFY. Results:During the six month, 53 fall events were detected and prevalence of fall was 29.4%. Among them, 28.6% were repeated fall. Among 169 patients, 20.7% of patients experienced fall. Decreased activities of daily living, transfer from bed, awakening at night, frequent toileting, using anticonvulsant, mean score of CMAI and modified Barthel’s scale were associated with future fall(p<0.05). Items were selected and weighted based statistical analysis. Overall predictive ability measured by AUC value of new 4 item scale was .774 and higher than that of Morse fall scale(.474) and STRATIFY(.660). Conclusion:Prevalence of fall in long term geriatric hospital was relatively high. Newly developed fall risk assessment tool could be used for reducing fall incidence.

치매 환자를 위한 성년후견제도의 성공적 정착을 위하여

윤종철(Youn, Jong-chul) 한국성년후견학회 2013 성년후견 Vol.- No.1

성년 후견제도의 성공적인 정착을 위해 제도의 준비상황에 대해 원칙부터 제도 운영에 이르기까지 다양한 문제점들을 현장 전문가의 입장에서 점검해보았다. For successful implementation of adult guardianship, situation of preparation including various issues from principle to operation of the policy was reviewed based on the position of clinical profession.

노인병원 근무자의 강박에 대한 인식도 예비조사

윤종철 ( Jong Chal Youn ),이남진 ( Nam Jin Lee ),이소애 ( So Ae Lee ) 한국정신병리진단분류학회 2009 精神病理學 Vol.18 No.1

Aim: This study aimed to investigate the awareness of staffs in elderly hospital on mechanical restraint use. Methods: A questionnaire on attitude and opinions regarding restraints was distributed to a convenience sample of 71 nurses and 149 care workers in elderly hospital, 93 nurses in mental hospital and 50 families of dementia patients. Results: In general, staffs in elderly hospital frequently involved in restraints. They held rather neutral opinions regarding the use of restraints. But, care workers insist on the positive effect of restraint. Staffs in elderly hospital thought that restraints were needed when patients had risk of fall, poor medical condition and many behavioral problems. About 40% of care worker in elderly hospital did not think that chest belt is a restraint. Conclusion: In general, staffs in elderly hospital especially for care worker had low level of awareness on restraint. Structured education program might be helpful for reducing restraint use in elderly hospital setting.

간편형 단서 회상 검사의 신뢰도와 타당도에 관한 연구

박은희 ( Eun Hee Park ),윤종철 ( Jong Chul Youn ),이소애 ( So Ae Lee ) 한국정신병리진단분류학회 2010 精神病理學 Vol.19 No.1

Objectives: We developed two parallel short cued recall tests(each SCRT A and SCRT B) and then carried out a reliability and validation study within a dementia-clinic setting using the tests. Our study aimed to assess its usefulness as a screening tool for memory problems related to dementia, especially the Dementia of Alzheimer`s Type. Methods: All of the subjects were community-dwelling Korean elderly aged 65 and older. The subjects consisted of 337 who were 109 normal controls, 116 patients with mild cognitive impairment, and 112 dementia patients. A psychiatrist with expert in dementia research made the diagnosis of dementia by doing clinical interviews and reviewing neuropsycholgical testing data of the subjects. Severity of dementia was staged using the extended version of Korean Clinical Dementia Rating(CDR) scale. All of the normal elderly were CDR 0 and all of the dementia patients were CDR 1 or 2. A translated Beck depression Inventory was administered to rule out pseudodementia due to depression. Equivalentform reliability coefficients and Test-retest reliability coefficients were calculated. To determine the construct validity of the SCRT, the participants received not only the SCRT but also the standardized Korean-version of Neuropsychological Assessment Battery CERAD(CERAD-K-N). To compare performances on the SCRT among three groups, Multivariate Analysis of Variance(MANOVA) was used. To measure the diagnostic accuracy of the K-MIS for dementia, the receiver operator characteristic(ROC) analysis was used. Results: Three groups did not show significant differences in demographic variables. Significant correlations were found between two alternative forms and between test-retest scores of SCRT. The SCRT scores were significantly correlated with memory measures of the CERAD-K-N(r= .540-.609, p<.01). According to MANOVA results, the performances on the SCRT were significantly differentiated among three groups(Walks Lamda=.134, F(4,316)=510.55, p<.001). The area under the ROC curve(AUC) of each SCRT A and B was .871 and .934, indicating the overall diagnostic accuracy of the SCRT is fairly high. The optimal cut off score for detecting dementia on the SCRT was 5/6. Conclusion: Our results indicate that the SCRT is a very brief and valid memory screening instrument for evaluating memory deficits of dementia patients while showing high sensitivity and specificity.

Design Study of a Compact Cyclotron for Accelerator Mass Spectrometry

Jong-Won Kim,윤종철,Min-Young Youn,Sonjong Wang 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.2

An accelerator mass spectrometer (AMS) utilizing a small cyclotron has been designed. The system has a mass resolving power of over 4000, which is sufficient to analyze a few AMS radioisotopes, including 14C, for tracing or chronometric dating. The cyclotron can provide a high resolving power with a large number of turns and a high harmonic operation of the rf system and has the advantage of using both negative and positive ions in the analysis. A high transmission efficiency is, in fact, a major goal in the design to compete with a Tandem AMS. A compact magnet with high stability, a sawtooth harmonic buncher and flat-topping rf system are the components adopted to achieve the goal. Also, large turn separations at injection and extraction are required, which can be done with adequate uses of the first harmonic component of the main magnetic field. The design of the cyclotron and injection beam line for the AMS has been studied. An accelerator mass spectrometer (AMS) utilizing a small cyclotron has been designed. The system has a mass resolving power of over 4000, which is sufficient to analyze a few AMS radioisotopes, including 14C, for tracing or chronometric dating. The cyclotron can provide a high resolving power with a large number of turns and a high harmonic operation of the rf system and has the advantage of using both negative and positive ions in the analysis. A high transmission efficiency is, in fact, a major goal in the design to compete with a Tandem AMS. A compact magnet with high stability, a sawtooth harmonic buncher and flat-topping rf system are the components adopted to achieve the goal. Also, large turn separations at injection and extraction are required, which can be done with adequate uses of the first harmonic component of the main magnetic field. The design of the cyclotron and injection beam line for the AMS has been studied.

Choline Acetyltransferase 유전자 다형성이 경도인지손상 발현에 미치는 영향

이정재,박준혁,이석범,허윤석,김태희,윤종철,주진형,이동영,박경운,김기웅,Lee, Jung-Jae,Park, Joon-Hyuk,Lee, Seok-Bum,Huh, Yoon-Seok,Kim, Tae-Hui,Youn, Jong-Chul,Jhoo, Jin-Hyeong,Lee, Dong-Young,Park, Koung-Un,Kim, Ki-Woong 대한생물정신의학회 2010 생물정신의학 Vol.17 No.4

Objectives : The potential association between choline acetyltransferase(CHAT) polymorphism and the risk of mild cognitive impairment(MCI) has not been investigated in Korea. We examined the main effect of CHAT polymorphism and its interaction with apolipoprotein E(APOE) polymorphism in the development of MCI in elderly Korean sample. Methods : We analyzed CHAT 2384G > A polymorphism and APOE polymorphism among 149 MCI subjects with MCI and 298 normal controls. We tested the association between MCI and CHAT A allele status using a logistic regression model. In addition, we employed generalized multifactor dimensionality reduction(GMDR) to investigate the interaction between CHAT and APOE with regard to the risk of MCI. Results : The CHAT A allele was associated with AD risk(OR = 1.59, 95% CI = 1.02-2.48, p = 0.042). No significant gene-gene interaction between CHAT and APOE was found in GMDR method(testing balanced accuracy = 0.540, p = 0.055). Conclusion : The CHAT A allele was associated with MCI risk in the Korean elderly. Its interaction with the APOE ${\varepsilon}4$ allele was not significant with regard to the development of MCI.

지역사회 경증치매환자를 대상으로 한 전산화 인지재활 치료(COMCOG) 효과

정원미(Jeong, Won-Mee),황윤정(Hwang, Yun-Jung),윤종철(Youn, Jong Chul) 한국노년학회 2010 한국노년학 Vol.30 No.1

본 연구는 시-지각 이론에 근거한 전산화 인지재활치료가 경증치매환자의 일상생활수행능력, 인지기능과 작업수행수준에 미치는 효과를 알아보고 치매환자를 위한 독립적인 지역사회에서의 적응을 위한 인지재활치료의 기초 자료를 제시하기 위함이다. 연구방법은 2009년 2월부터 2009년 8월까지 용인시 치매예방관리센터에 내원한 경증 치매환자 14명을 대상으로 5주 동안 주 2회, 총 10회 가정 방문하여 전산화인지재활치료를 실시하였다. 전산화인지재활치료는 시-지각이론의 틀에 근거하여 실시하였다. 알쯔하이머치매군과 비알쯔하이머치매군을 대상으로 치료 전후의 일상생활수행능력, 인지기능과 작업수행기능에 미치는 효과를 검증하기 위한 유사실험연구로써 단일군 전후실험설계를 적용하였다. 연구결과는 첫째, 전산화인재활치료 실시 전에 비하여 실시 후에 경증치매환자의 일상생활수행능력, 인지수준판별검사 등의 인지기능과 작업수행 만족도가 통계적으로 유의하게 증가하였다(p<.05). 둘째, 비알쯔하이머치매군에 비하여 알쯔하이머치매에서 인지기능의 변화에 유의한 효과가 있었다(p<.05). 따라서 시-지각 이론의 틀에 근거한 전산화 인지재활치료는 지역사회에 거주하는 경증치매환자의 전반적인 인지기능 및 일상생활수행능력 향상에 효과적으로 보인다. 또한 인지기능과 일상생활 독립성의 증가로 인하여 작업수행에 대한 만족감도 증가에도 효과적이었다. 앞으로 지역사회에 거주하는 경증치매환자의 기능향상을 위한 보다 다양한 인지재활 프로그램에 대한 연구가 필요하다. This study aims to understand the effects of a Computer - based Cognitive Rehabilitation Therapy(CBCRT) evidence based on mild dementia patients' ability to activities daily living(ADL), cognitive function and measure of occupational performance and to suggest basic data for a cognitive rehabilitation therapy for dementia patients. Method : A CBCRT was applied two times a week for 5 weeks to 14 mild dementia patients who visited Yongin Center for Managing Dementia in Gyeongi-do between February and August 2009. Based on frame of reference for Visual-Perception a CBCRT was applied at home. Moreover, a one group pretest-post test design was, which is a quasi-experiment and research, also applied in order to verify the effects of the rehabilitation therapy on the subjects' ability to ADL, cognitive function and occupational performance skills. Results: A significant effect was confirmed (p<.05) from the CBCRT which Assessment of Motor and Process Skills(AMPS) processing skills and cognitive function and occupational performance skills. Neither was found any significant effect in improving motor skills from AMPS. Conclusion: It seems that a CBCRT based on evidence and has an effect on the improvement of the ability to ADL and cognitive function of mild dementia patients living in a community. The present author hopes that, in the future, more cognitive rehabilitation programs will be developed to improve the functions of mild dementia patients living in a community.