http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
만성 C형 간염 환자에서 Interferon-${\alpha}$를 투여중 발생한 간질성 폐렴 1예
윤종구,안중현,고승현,이현승,권순석,김영균,문화식,박성학,송정섭,Yoon, Jong Goo,Ahn, Joong Hyun,Ko, Seung Hyeon,Lee, Hyun Seoung,Kwon, Soon Seog,Kim, Young Kyoon,Moon, Hwa Sik,Park, Sung Hak,Song, Jeong Sup 대한결핵및호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.4
만성 C형 간염환자에서 IFN으로 치료중에 발생된 간질성 폐렴은 매우 드물고 아직까지국내에는 보고된 바 없었다. 저자들은 만성 C형 간염환자가 IFN-${\alpha}$를 투여받던 중에 기침과 호흡곤란을 주소로 내원하여 간질성 폐렴으로 진단된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Interstitial pneumonitis associated with interferon alpha therapy for chronic hepatitis C was first describe6 in 1994 by Kazoo et al In Japan. The mechanism of interstitial pneumonitis developed by interferon alpha was still unknown but immunologic, allergic of direct lung toxicity were suggested. We experienced a case of interstitial pneumonitis developed during interferon alpha therapy for chronic hepatitis C in a 52-year-old male patient. He was treated with 6 million units of interferon alpha intramuscularly 3 times per week for 4 weeks and noted progressive dyspnea and cough. These symptoms were subsided after 6 weeks' discontinuation of interferon alpha therapy. And so, he was retreated with 3 million units of interferon alpha 3 times per week for 8 weeks and felt dyspnea again. He was admitted to our hospital for further evaluation of progressive dyspnea. Arterial blood gas(ABG) values were $PaO_2$ 90.7 mmHg and $PaCO_2$ 31.9 mmHg, and antinuclear antibody(ANA) was negative. A chest X-ray film revealed diffuse reticulo-nodular shadows in bilateral lung fields, suggesting a diagnosis of interstitial pneumonitis. A marked increase in lymphocyte count and suppressor T cell were observed in bronchoalveolar lavage(BAL) fluid. Lymphocyte stimulation test with interferon alpha was positive. Interstitial pneumonitis was confirmed by transbronchial lung biopsy. After discontinuation of interferon alpha, we gave oral steroid in the condition that clinical symptoms were being improved gradually.
만성 C형 간염 환자에서 Interferon-α를 투여중 발생한 간질성 폐렴
윤종구 ( Jong Goo Yoon ),안중현 ( Joong Hyun Ahn ),고승현 ( Seung Hyeon Ko ),이현승 ( Hyun Seoung Lee ),권순석 ( Soon Seog Kwon ),김영균 ( Young Kyoon Kim ),문화식 ( Hwa Sik Moon ),박성학 ( Sung Hak Park ),송정섭 ( Jeong Sup So 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.4
윤종구 ( Jong Goo Yoon ),김재광 ( Jae Kwang Kim ),이대훈 ( Dae Hoon Lee ),김진일 ( Jin Il Kim ),김상우 ( Sang Woo Kim ),김성수 ( Sung Soo Kim ),방춘상 ( Chun Sang Bang ),양영상 ( Young Sang Yang ),조세현 ( Se Hyun Cho ),박수헌 ( S 대한소화기학회 2000 대한소화기학회지 Vol.36 No.3
Background/Aims : The aim of this study was to investigate whether the epidemiologic patterns of peptic ulcer can be changed by environmental changes. Methods: We studied 1,263 patients with peptic ulcer and the results were compared with those of 8 years age. Results: Of 1,263 cases, patients with gastric ulcer (GU), duodenal ulcer, and combined ulcer (CU) are (44.3%), (41.4%), and (14.3%), respectively. Those in 8 years ago were (41.5%), (51.4%), and (7.1%), respectively. The mean age of the patients with GU, DU, and CU are 52.9, 42.8, and 50.0 years, respectively. Those in 8 years ago were 50.3, 39.6, and 47.3 years, respectively. The mean age of patients with gastric ulcer, duodenal ulcer, and combined ulcer was 52.9±13.0 years vs. 50.3±14 years, 42.8±13.0 years vs. 39.6±12 years, and 50.0±13.0 years vs. 47.9±13 years respectively. The percentage of smokers (GU:86.6%, DU:79.5%) in male with peptic ulcer was higher than 73% in the general population. Conclusions : Comparing this results with the those of eight years ago, we found the increased incidence of gastric ulcer, and the decreased recurrence of peptic ulcer. These differences may be due to the increase of aged population, increased association with NSAIDs, and increased eradication rates of H. pylori. (Kor J Gastroenterol 2000;36:336 - 347)
포스터 전시 : 상부위장관 11 ; H. pylori 감염을 동반하지 않은 MALT (Mucosa-Associated Lymphoid Tissue) 임파종 환자의 1예
이정록 ( Jeong Rok Lee ),한상우 ( Sang Woo Han ),김명철 ( Myoung Cheol Kim ),윤종구 ( Jong Goo Yoon ),김병욱 ( Byung Wook Kim ),김상우 ( Sang Woo Kim ),김성수 ( Sung Soo Kim ),이동수 ( Dong Soo Lee ),채현석 ( Hyun Suke Chae ),최 대한소화기학회 2002 대한소화기학회 추계학술대회 Vol.2002 No.-
반복성 늑막삼출로 발현된 Boerhaave 증후군 1 예
김선화,최명규,방춘상,윤종구,이동수,김성수,김상우,강미자,한석원,채현석,추교영,천지성,이대훈 대한소화기학회 2000 대한소화기학회지 Vol.36 No.6
Spontaneous rupture of the esophagus is an uncommon disease which was firstly reported by Boerhaave in 1724. It can cause fatal results unless diagnosed and treated early. Delayed diagnosis is mostly caused by lack of knowledge and atypical clinical symptom. Its mortality increases proportionally to the time between esophageal perforation and treatment. We experienced a case of spontaneous esophageal perforation. The patient was a 40-year-old alcoholic, who complained of epigastric, shoulder, and back pain following forceful hematemesis. The results of chest X-ray was normal on admission. Alcoholic delirium tremens developed 12 hours after admission. On the 3rd hospital day, massive preural effusion developed. Pleural effusion was drained completely and recurred on the 4th hospital day. Under the suspicion of esophageal rupture, we performed chest computed tomography, which revealed airs, fluids, and tiny soft tissue densities in the mediastinum. Operation was performed on the 4th hospital day. There was a 7-8 cm sized longitudinal tearing in lower esophagus. He died 5 days after operation.
최규용,김진일,이대훈,한석원,윤종구,송호진,성용직,오수혁,장우임,김병욱,박수헌,선희식 대한소화기학회 2001 대한소화기학회지 Vol.37 No.1
Metastatic cancer of the umbilicus is very rare and is called Sister Mary Joseph's nodule. The most common primary site of umbilical metastasis is an adenocarcinoma of the stomach and the incidence of pancreatic carcinoma is less than 10% of umbilical metastases. Metastasis to the umbilicus usually presents as diffuse spreading of primary cancer or recurrence after treatment of primary cancer, resulting in inoperability and poor prognosis. However, umbilical metastasis presents rarely as a first sign of primary cancer and leads to its diagnosis. We report a case of umbilical metastasis as a presenting sign of pancreatic adenocarcinoma. The patient was a 38-year-old woman who had a nodule in the umbilicus and suffered from abdominal pain around the umbilicus. Histologic findings of the umbilical nodule showed poorly differentiated adenocarcinoma. Abdominal computed tomography showed a pancreatic tail mass. Ultrasonography-guided aspiration biopsy of the pancreas also revealed poorly differentiated adenocarcinoma almost identical to the pathologic finding of the umbilicus.
이상준,박순민,이영석,한남익,윤종구,이종민,한석원,문건웅,윤인재,천지성,정정조,서백종 대한소화기학회 1998 대한소화기학회지 Vol.30 No.5
Background/Aims: The Krukenberg tumor is a metastatic or primary ovarian tumor of the signet-ring cell type. The incidence of this tumor are high in Korea, especially among relatively young age group, and the prognosis is poor. Therefore we tried to understand the relationship between the many factors and survival periods. Methods: We have observ d 12 cases of Krukenberg tumors from January 1984 to February 1997 in Holy Family Hospi:al and analyzed them. Results: The Krukenberg tumor accounts for 14.1% among the 85 malignat ovarian tumor and 3.5% among the 342 female gastric cancers found in our hospital during this period. The age distribution of the patients ranged from 25 to 50 years of age and the majority were under 40 years of age. The mean age was 34.2 years. Initial chief complaints were epiga.tric pain, lower abdominal pain, and lower abdominal mass. The sizes of Krukenberg tumors range from 7.2cm to 18.0cm and the tumors were usually bilateral. From diagnosis to death, the mean duration of survival was 6.7 months. But it was 9.0 months in cases where an operation on the ovaries and the primary site, were performed. In the group of ascites(8 cases), it was 2.6 months contrary to 14.8 months of ascites-free group. Conclusions: The prognosis of the Krukenberp tumor depends on early diagnosis and aggressive treatrnent.