『마법사』에 드러난 존 파울즈의 교훈적 예술관

윤영필 21세기영어영문학회 2005 영어영문학21 Vol.18 No.1

While vigorously searching for a new novel form to accommodate the contemporary theoretical insight into the nature of language and novel, John Fowles pays great, though not devoid of irony, homage to the tradition of realism novel. His novels are permeated with his firm belief in the moral, didactic power of art to bring changes to life. This essay tries to show how his didactic intention informs the whole narrative of The Magus, one of his most comprehensive and compelling works. The Magus is a peculiar sort of Bildungsroman, a novel of education and growth, replete with metafictional elements, which also serve to enhance the aesthetic education of the reader. Nicholas, the protagonist of the novel, whose logical and cautiously sceptical attitude invites the reader to identify with him, plays the role of reader as he is induced into an active participation in and interpretation of the metatheatrical ‘godgame’ of Conchis who stands for the metaphorical fictional world. Going through it under the enigmatic direction of Conchis, Nicholas gradually gets over his evasive attitude towards reality as well as his escapist aesthetics. Also his self-centered, life-denying cynicism gives way to a new perception of the mysterious reality of life itself, combined with his growing understanding of the existential human condition. The concluding section of this essay thinks over a few problems regarding the author's overt didacticism in this novel, casting a last short glance at the ironical fact that, over the whole period of his writing, he failed to make much progress in his own existential ideas in spite of his unremitting passion for education.

텍스트성과 소설: 파울즈의프랑스중위의 여자

윤영필 영미문학연구회 2005 안과 밖 Vol.19 No.-

인간, 동물, “존재의 충만함”: 쿳시와 로렌스

윤영필 한국로렌스학회 2017 D.H. 로렌스 연구 Vol.25 No.2

Focusing on J. M. Coetzee’s “the Lives of Animals,” this essay purports to probe his thinking on ‘the question of the animal’ and compare it with that of D. H Lawrence. These two pieces of writing were originally presented as lectures, then published as a book under the same title, and finally incorporated into a novel titled Elizabeth Costello. In the novel, the eponymous main character gives a series of lectures in which she presents herself as ‘an animal’, deeply wounded by sufferings of animals in the world today and people’s indifference to them. She vehemently criticizes the anthropocentric understanding of animals in the Western philosophy, putting emphasis on fullness of being, embodiedness, and joy of life. Through her lectures and other related scenes, Coetzee explores the possibility of an ethical relationship between humans and animals, based on the vulnerability and finitude of embodied beings. With his extraordinary sense of nonhuman otherness of animals and their fullness of being, Lawrence has also made a powerful denunciation of anthropocentrism and sought for a vital relationship with animals throughout his oeuvre. Yet there is a crucial difference between the two writers: Lawrence pays attention not only to the dimension of ‘being’, but also to that of ‘existence’, in which conflicts between species are inevitable, while Elizabeth or Coetzee exclusively focuses on the former and chooses to live as a vegetarian. The essay concludes with examining the implications of this difference in view of epochal change lying between them.

Akin 절골술의 내측 횡 봉합사 고정: 술기 보고

윤영필,김상환,Yune, Young-Phil,Kim, Sanghwan 대한족부족관절학회 2015 대한족부족관절학회지 Vol.19 No.4

The Akin osteotomy is a complimentary procedure in hallux valgus surgery. Surgical techniques may vary depending on the operators or fixation devices. Suture fixation, for which a removal procedure is not necessary, can often be recommended. However, there is a risk of failure due to the thin cortex of the phalanx. We describe a new technique using Ethibond suture fixation in Akin osteotomy, which can lower the risk of phalangeal cortical failure and articular cartilage irritation. First, the Akin osteotomy was performed on the proximal phalanx 5 to 6 mm distal to the first metatarsophalangeal joint. Then bone holes were drilled from dorsum to plantar parallel to osteotomy with the Kirschner wire. The final procedure involved passing the Ethibond sutures connected to a straight needle through the holes and tying it. This fixation method offers an effective and easy technique for performance of Akin osteotomy.

제 2차 세계대전 이후의 영국소설

윤영필 영미문학연구회 1997 안과 밖 Vol.3 No.-

N/A

몸을 사유하기: D. H. 로렌스와 장-뤽 낭시(Jean Luc-Nancy)

윤영필 한국로렌스학회 2022 D.H. 로렌스 연구 Vol.30 No.1

In the midst of overflowing discourses on the body, this paper aims to compare Lawrence’s thinking of the body with that of Jean-Luc Nancy and gain a new understanding of the nature of the body. Pointing out that the body is not an object of knowledge, but an experience in itself, both of them emphasize that the body is open to itself and to other bodies. For Nancy, the body, an open space where existence takes place, is not a substance. It always comes to its presence; it is an aperture, a self in departure, repeating its movements of arriving and withdrawing. Also a body cannot exist alone; it co-exists; it is exposed to other bodies, always already in touch with them. Lawrence, with his relational thinking and his firm belief in the ever-flowing, living present of being, shares these ideas and explores how man can achieve a harmonious relationship with his circumambient universe, avoiding the disastrous damages brought about by the death of the body in the modern society. There is, however, an unbridgeable gap between their thoughts. While Lawrence lays stress on the integrity of embodied self, Nancy argues that the body, constituted by fragmentation of parts and division of senses, is never completely whole nor proper. This discord reminds us of the elusiveness of the body that demands continual efforts to keep our thinking in contact with it.

Enhanced Effects of Osteoclastogenesis Inhibition by Curcumin-Delivering Heparin Nanoparticles

윤영필,박경순,김성은,이재용,김학준,최성욱,송해룡 한국고분자학회 2014 Macromolecular Research Vol.22 No.6

Curcumin has various pharmacological activities such as anti-inflammatory, antioxidant, antimicrobialand antitumor activity. However, its use has been limited due to its poor solubility in water and minimal systemicbioavailability. Thus, we developed curcumin-delivering heparin-based nanoparticles and evaluated the inhibitioneffects of osteoclastogenesis by curcumin-delivering heparin nanoparticles (Cur-HD NPs). Cur-HD NPs were dispersedwell in aqueous solution by forming self-assembled nanoparticles and showed sustained release of curcumin. In vitro studies, HD NPs facilitated intracellular delivery of curcumin into macrophages and osteoclasts, and thus,Cur-HD NPs effectively inhibited osteoclastogenesis in a dose-dependent manner by suppressing tartrate-resistantacid phosphatase (TRAP) activity and TRAP-positive multinucleated cells as well as by reducing the expression ofosteoclast marker genes (i.e., TRAP and nuclear factor of activated T cells cytoplasmic 1 (NFATc1)). Furthermore, Cur-HD NPs markedly stimulated apoptosis of osteoclasts. Therefore, we hope that Cur-HD NPs will be useful nanodrugs forthe treatment of bone-related diseases.

Improvement of Osteoblast Functions by Sustained Release of Bone Morphogenetic Protein-2 (BMP-2) from Heparin-coated Chitosan Scaffold

윤영필,이수영,김학준,송재준,김성은 한국조직공학과 재생의학회 2013 조직공학과 재생의학 Vol.10 No.4

The aim of this study was to investigate the improvement in osteoblast functions by using bone morphogenetic protein-2 (BMP-2) immobilized heparin-coated chitosan scaffolds and comparing it with that using chitosan scaffold or BMP-2/chitosan scaffold in vitro. BMP-2 was released from the heparin-coated chitosan scaffold in a sustained manner compared to that released from the chitosan scaffold. The osteoblast functions of MG-63 cells grown on the chitosan scaffold, the BMP-2/chitosan scaffold, the BMP-2/Hep/chitosan scaffold were investigated by assessing cell proliferation,alkaline phosphatase (ALP) activity, calcium deposition, and gene expression. The results of the in vitro studies demonstrated that MG-63 cells grown on the BMP-2/Hep/chitosan scaffold showed a significant increment in ALP activity, and calcium deposition as compared to those grown on the chitosan scaffold by sustained release of BMP-2 due to the influence of heparin. Therefore, BMP-2 immobilized heparin-coated chitosan scaffolds are promising materials for improving osteoblast functions through sustained release of BMP-2.

대처시대를 전후한 영국 노동계급의 위기 팻 바커의 『유니언 스트리트』와 『리자의 영국』

윤영필 영미문학연구회 2009 안과 밖 Vol.0 No.26

Paying attention to the alleged demise of working­class novels, this paper situates Pat Barker’s two working­class novels, Union Street and Liza’s England in the historical context of 1980s England when Thatcher’s neoliberalism began to gain momentum, and probes how they represent the drastic changes and disruption of working­class communities, respectively in the 1970s and 1980s, which were caused in the main by deindustrialization and accelerated by the hostile labor policy of the Thatcher government. It will turn out that these novels, illuminating the lives of working­class women hitherto neglected in the literary representation, not only redress the main tradition of English literature, but make a timely critical intervention in the contemporary political and cultural milieu in which ‘class’ tends to be deliberately excluded from the agenda of public discussion; and that, thematizing the significance of historical memory, especially in Liza’s England, they also enact a gesture of resistance both to Thatcher’s cultural policy that subjects the cultural values with their deep historical implications to the market principles, and to the loss of historical consciousness characteristic of postmodernism.

위기 너머를 꿈꾸며

윤영필 영미문학연구회 2011 안과 밖 Vol.0 No.31