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      • KCI등재

        당뇨병성 케톤산증에 대한 임상적 고찰

        서강석,이정헌,박정배,김종근,윤영국 대한응급의학회 1998 대한응급의학회지 Vol.9 No.1

        Background: Diabetic ketoacidosis(DKA) is serious acute metabolic complication and the most important cause of high morbidity and mortality of diabetes. The object of this study is to examine the clinical characteristics of patients with DKA who had a prior history of diabetes or not. Method: Authers reviewed retrospectively the medical records of 49 cases adimitted to Kyungpook National University Hospital from January 1991 to June 1997 with a diagnosis of DKA and classified cases as type I, type II and newly diagnosed diabetics according to prior history of diabetes. Results: 1. Of 49 cases of DKA, 24(49%) were classified as type I, 17(35%) as type II from data available in the medical records, and 8(16%) had DKA as the initial manifestation of the diasease. 2. The male to female ratio was 0.5:1 in type I, 1.1:1 in type II and 1.7:1 in newly diagnosed diabetics, and the mean age was 24.4 in type I, 57.9 in type II and 23.9 years old in newly diagnosed diabetics. 3. The mean duration between initial diagnosis of diabetes and the occurrence of DKA was 2.6 in type I and 6.9 years in type II diabetes. The occurrence of DKA within 2 years of initial diagnosis of diabetes was 54% in type I and 18% in type II diabetes, but the occurrence of DKA after 5 years of initial diagnosis of diabetes was 17% in type I and 47% in type II diabetes. 4. The precipitating factors of DKA were identified in 88% in type I, 76% in type II and 38% in newly diagnosed diabetics, and the most common precipitating factor was omission of treatment in both type I and type II(type I: 56%, type II: 35%). 5. The altered mental status was correlated with incresed osmolality(p<0.05), but not with other laboratory values such as pH, bicabonate, glucose, anion gap and dehydration status(p<0.05). Conclusion: It is necessary to conduct early aggressive evaluation for early diagnosis and proper treatment of DKA, because DKA occurs in patients with prior history of type II diabetes and without prior diabetic history as well as patients with prior history of type I diabetes.

      • KCI등재

        노인외상환자의 사망률에 영향을 미치는 인자

        김종근,최마이클승필,이정헌,박정배,서강석,윤영국 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.3

        Background : The goal of this study is to identify the factors that predict mortality in elderly trauma patients. Methods : We reviewed retrospectively the medical record of 144 cases of geriatric trauma admitted to Kyungpook National University Hospital from January 1998 to December 1998. We evaluated the general characteristics, mechanisms of injury, Revised Trauma Score(RTS), Injury Severity Score(ISS), Probability of survival(Ps) by TRISS(Trauma and Injury Severity Score) method, amount of blood transfused, preexisting disease, complications, length of stay, and mortality. Results : 1. The mean age was 75.39 ±7.89 years old, and male to female ratio was 0.89:1. 2. The mechanisms of injury were primarily falls(56.3%) followed by bicycle or motorcycle(13.9%), and pedestrian injuries(13.2%) and motor vehicle accidents(6.9%). 3. The mean Glasgow Coma Scale(GCS), RTS and ISS are 13.3 ±3.5, 7.2 ±1.4 and 14.2 ±11.6 respectively. 4. The actual mortality rate was 18.1% (26/144명). But by TRISS method, predicted mortality rate was 9.3%(12.5/144명), excess mortality rate was 108% and Z score was 3.99 indicating that actual number of death exceed predicted number of death. 5. Between the survivors and nonsurvivors, the results were significantly different as follows ; systolic blood pressure(141.9 ±28.3 vs. 116.8 ±48.7 mmHg), GCS(14.3 ±2.0 vs. 9.0 ±5.1), RTS(7.8 ±0.7 vs 5.4 ±2.3), ISS(11.3 ±5.6 vs 27.2 ±20.2), Ps by TRISS(0.97 ±0.06 vs 0.65 ±0.37), preexisting diseases(50.8 vs 69.8%). Conclusion : Geriatric patients are more likely to die after trauma than other age groups. The cause of higher actual mortality rate compared to predicted mortality rate was considered as the higher incidence of delayed death due to sepsis or multiple organ failure. In order to reduce the mortality, even with relatively stable initial vital sign, invasive hemodynamic monitoring and intensive treatment are recommended and also, prevention and treatment of nosocomial infection are very important.

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