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고해상도 타이핑을 이용한 돼지 주조직적합성복합체 SLA-2 유전자의 신규 대립유전자발굴
육승연,강민규,전효임,박찬규 한국동물유전육종학회 2021 한국동물유전육종학회지 Vol.5 No.3
The genetic diversity of the major histocompatibility complex (MHC) molecules of pigs has not been thoroughly characterized. In this study, we successfully typed SLA-2, a pig MHC class I gene, from 10 pigs of five different breeds using a high-resolution typing method. We identified a total of 14 SLA-2 alleles including 2 previously unreported alleles and reported to IPD-MHC SLA database. These new alleles showed 1 and 29 nucleotide differences from the closely related alleles, SLA-2*10:01 and SLA-2*13:02, respectively. The information of SLA new alleles should enrich our understanding the diversity of MHC diversity in pigs.