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L1210 및 $P388D_1$에 대한 고삼 추출물의 세포독성에 관한 연구(II)
조훈,양은영,김종수,유일수,류도곤,강길웅,이정호,백승화,Cho, Hoon,Yang, Eun-Yeong,Kim, Jong-Soo,Yoo, Il-Soo,Ryu, Do-Gon,Kang, Kil-Ung,Lee, Jeong-Ho,Baek, Seung-Hwa 한국생약학회 1999 생약학회지 Vol.30 No.4
This study was carried out to evaluate cytotoxicity of the extracts from Sophora flavescens Ait. against L1210 (lymphocytic leukemia) and $P388D_1$ (lymphoid neoplasms) cells in vitro. We have determined cytotoxicity by MTT {3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazo-liumbromide} assay. The order of cytotoxicity of Sophora flavescens Ait. extracts against L1210 and $P388D_1$ cells in vitro is as follows: AM> EASF > CFSF > MTSF > WSF > HXSF and AM> EASF> CFSF> MTSF> HXSF> WSF. These results suggest that the ethyl acetate soluble extract of Sophora flavescens Ait may be a valuable choice for the development of antitumor agents.