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토사자(兎絲子) 약침(藥鍼)이 자연발증(自然發證) 고혈압(高血壓) 백서(白鼠)의 혈압(血壓)에 미치는 영향(影響)
유윤조,한정우,육태한,이호섭,Yu Yun-Cho,Han Jeong-Woo,Yuk Tae-Han,Lee Ho-Sub 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2
The aim of the experiments was to investigate the effect of Semen Cuscutae aqua-acupuncture at the meridian point BL 20(脾兪) and BL 23(賢兪) on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide (ANP) in spontaneously hypertensive rats (SHR). The results of this study were as follows: 1. Systolic blood pressure was decreased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20, BL 23. 2. Plasma renin activity was increased significantly after Semen Cuscutae aqua-acupuncture at meridian point BL 23, BL 20. 3. Plasma levels of aldosterone was increased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20. 4. Plasma levels of atrial natriuretic peptide (ANP) was increased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 23, but it was decreased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20. These results suggest that the changes of the depressor response after Semen Cuscutae aqua-acupuncture at the meridian point BL 20, BL 23 are related to the changes of the plasma renin activity, plasma levels of atrial natriuretic peptide (ANP) and aldosterone.
흰쥐의 성별과 주령에 따른 족삼리(足三里) 위유(胃兪) 중완(中脘) 배혈(配穴) 시구(施灸)가 소장(小腸)수송능에 미치는 효과
유윤조 ( Yun Cho Yu ),권오상 ( O Sang Kwon ),오인균 ( In Kyun Oh ),양승범 ( Seung Bum Yang ),안성훈 ( Seong Hoon Ahn ),손인철 ( In Chul Sohn ),김재효 ( Jae Hyo Kim ) 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.4
Objetives: The aim of this study was to observe the effect of moxibustion at combined acupoints of ST36, BL21 and CV12 in rats with sex and age. Methods: This study measured small intestinal motility in rats. First, cauterize with moxa was applied 5 times to the ST36, BL21 and CV12 in rats classified by sex and age under enflurane anesthesia. And then same treatment is done to mached acupoints of ST36, BL21 and CV12. Results: In single acupoint groups, cauterizing with moxa on ST36 increased with 5, 7 weeks in female and all weeks in male. The BL21 group increased with 5, 6, 7 weeks in female, and only 5 weeks in male. The CV12 group showed increasing with 5, 6 weeks in female and only 7 weeks in male. In combined acupoints groups, the ST36+BL21 with 8 weeks in male, the ST36+CV12 with 5, 8 weeks in female and 5, 6, 8 weeks in male, the CV12+BL21 only with 5 weeks in female, the ST36+BL21+CV12 only with 5 weeks in female showed increasing, respectively. Conclusions: Although these differents according to the sex and age in rats do not have a established tendency, the results suggested that the effects of moxibustion are experimentally should be considered the sex and age of individual.
위, 소장, 대장의 하합혈 침구자극이 Loperamide로 유발된 변비의 장관 운동성에 미치는 영향
유윤조 ( Yun Cho Yu ),권오상 ( O Sang Kwon ),양승범 ( Seung Bum Yang ),김민수 ( Min Su Kim ),김재효 ( Jaehyo Kim ) 경락경혈학회 2013 Korean Journal of Acupuncture Vol.30 No.4
Objectives: The aim of this study was to observe effects of manual acupuncture (MA), electro-acupuncture (EA) and moxibustion (MO) on the rat with loperamide-induced constipation. Methods: This study measured small intestinal motility and number of fecal pellets in rats with loperamide induced constipation. MA and EA (intensity, 5 times muscle twitch threshold) was applied for 30 minutes and MO was treated on 5 times moxa cautery to the groups divided with age and sex. Results: The small intestinal motility was decreased by ST36 EA and ST37 EA in 5 weeks male group and ST37 EA in 7 weeks male and female groups, and ST36 MO in 7 weeks female group, but it was increased by ST39 EA in 7 weeks male group and ST37 MO and ST39 MO in 7 weeks male group. The number of fecal pellets was decreased by MA, EA, MO of ST36 in all group except 5, 7 weeks male groups only, and MA, EA of ST37 in 5, 7 weeks male group and ST37 MO in 7 weeks female group, and ST39 EA in 5 weeks male group and 7 weeks female group and ST39 MO in 7 weeks female group, but increased by ST37 EA in 5 weeks female group and ST39 EA in 7 weeks male group. Conclusions: Although these differences do not have a established tendency, it suggests that acupuncture and moxibustion are experimentally dependent upon the sex and age on intestinal motility in rats.
족삼리와 양릉천의 침, 전침과 경혈단위 전침기구 자극이 혈중 Gastrin 농도에 미치는 영향
안점우,유윤조,김정연,An, Jeorn-woo,Yu, Yun-cho,Kim, Jeong-yun 대한침구의학회 2004 대한침구의학회지 Vol.21 No.3
It is well known that acupuncture is effective for treatment of gastric disease in human. For years, we have been utilizing a electro-acupuncture(EA) in attempt to manage gastric symptoms. However, the data on clinical effectiveness is conflicting and the action of acupoints is unclear. The purpose of this study was to investigate the effects of manual and electro acupuncture(EA) at acupoints of ST 36 and GB 34 on the serum gastrin level by radioimmunoassay in rats. All of acupuncture treatment was applied to the acupoints for 30 min during 3 days. Manual acupuncture with both acupoints resulted in increased gastrin serum level when compare to control group treated with only anesthesia. Either high (100 Hz) and low (2 Hz) frequency EA at ST 36 decreased gastrin serum level compared with control group, but EA at GB 34 conversely increased. In EA with device was designed stimulating only acupoint(New EA), either low frequency on ST 36 and high frequency on GB 34 unusually increased gastrin serum level compared to control group. The results of this experiment suggest that many factors, such as the selection of acupoints, the manipulation and the specification of acupuncture device, are capable of affecting acupuncture effects.
합곡(合谷)·태충(太衝), 간유(肝兪)·대장유(大腸兪) 동시(同時) 취혈(取穴)이 정상(正常) 백서(白鼠) 위기능(胃機能)에 미치는 영향(影響)
김용정,유윤조,김강산,Kim, Yong-jeong,Yu, Yun-cho,Kim, Kang-san 대한침구의학회 2004 대한침구의학회지 Vol.21 No.3
Objective : This study was designed to investigate the effects of acupuncture, moxibustion and electro-acupuncture at LI4 and LR3, BL18 and BL25 on serum gastin level in rats. Methods : LI4 and LR3 which belong to Large Intestine Meridian and liver Meridian are acupuncture points frequently used for healing gastrointestinal disease in oriental medicine. BL18 and BL25 which belong to Bladder Meridian are acupuncture points used for healing hepatic disease and intestinal disease in oriental medicine. Serum gastrin level by radioimmnunoassay was measured at 3 days after acupuncture, moxibustion and electro-acupuncture of those acupoints. Results & Conclusion : Moxibustion applied to the BL18 acupoint, BL25 acupoint decreased gastrin level of serum, but moxibustion applied to the BL18+BL25 acupoints did not produced significant effect. Acupuncture applied to the LI4 acupoint, LR4 acupoint did not produced significant effect, but acupuncture applied to the LI4+LR4 acupoints increased gastrin level of serum, Electro-acupuncture applied to the LI4 acupoint, LR4 acupoint increased gastrin level of serum, and electro-acupuncture applied to the LI4+LR4 acupoints also increased gastrin level of serum.
전침(電鍼)의 Prameters에 대한 실험(實驗)적 연구-자극시간(刺戟時間), 시술(施術)기간, 자극(刺戟)깊이를 중심으로-
윤정안,유윤조,김강산,김경식,김홍훈,김대중,조남근,Yun, Jeong-ahn,Yu, Yun-cho,Kim, Kang-san,Kim, Kyung-sik,Kim, Hong-hoon,Kim, Dae-joong,Cho, Nam-geun 대한침구의학회 2005 대한침구의학회지 Vol.22 No.1
침(鍼) 치료효과(治療效果)에 영향을 주는 자극(刺戟) 시간(時間)과 자침(刺鍼) 깊이 및 시술(施術) 기간(期間)에 따른 효과차리(效果差異)를 관찰하기 위하여 족삼리(足三里)에 전침(電鍼)을 사용하여 위산분비를 촉진시키는 호르몬인 혈중 gastrin 농도의 변화를 관찰하여 다음과 같은 결과를 얻었다. 1. 자침 시간의 비교에서 10분, 30분 실험군에서는 대조군에 비하여 혈중 gastrin 농도를 유의하게 증가시켰으나, 60분 실험군에서는 변화를 관찰할 수 없었다. 2. 시술 기간의 비교에서 5일과 10일 실험군에서는 대조군에 비하여 혈중 gastrin 농도를 유의하게 증가시켰으나, 1일 실험군에서는 변화를 관찰할 수 없었다. 3. 자침 깊이의 비교에서 전체자극군과 피부자극군에서는 대조군에 비해 혈중 gastrin 농도를 유의하게 증가시켰으나, 심부자극군에서는 변화를 관찰할 수 없었다. 이상의 결과로 미루어 침 치료효과를 실질적으로 향상시키기 위해서는 영향을 줄 수 있는 다양한 인자들에 대한 실험적, 임상적 비교 연구가 진행되어 임상과 기초이론에 활용할 수 있는 자료가 구축되어야 할 것으로 사료된다.