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      • KCI등재

        미니돼지에서 Acellular dermal matrix에 배양된 치주인대섬유모세포을 이용한 자가치아이식술: 치주인대로써의 잠재력에 대한 조직학적 평가

        유상준,김병욱,박주철,장현선,Yu, Sang-Joun,Kim, Byung-Ock,Park, Joo-Cheol,Jang, Hyun-Seon 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.1

        The aim of this study was to examine the possibility of periodontal ligament regeneration when autotransplantation was used by the periodontal ligament fibroblasts cultured on the acellular dermal matrix in teeth without a periodontal ligament. One minipig was used in this study. The mandibular and maxillary permanent incisors were ex-tracted for the culture of the periodontal ligament cells. The roots of the unextracted teeth were classified into a positive control group, in which the normal periodontal ligament was preserved. The roots of the extracted teeth were divided into the following two groups: The negative control group, in which the periodontal ligament had been removed and the acellular dermal matrix was not applied; and an experimental group, in which the periodontal ligament had been removed and periodontal ligament fibroblast cultured on an acellular dermal matrix was applied. The prepared teeth were transplanted, and completely submerged using physical barrier membranes. The animal was sacrificed 4 weeks after the autotransplant. The transplanted teeth were examined histologically. In this study, the periodontal ligament was normal in the positive control group, and ankylosis was discovered on the denuded root surface in the negative control group. Periodontal ligament-like connective tissue was found adjacent to the denuded root and the new cementum-like layer of hard tissue was formed in the experimental group. These results suggest that the periodontal ligament fibroblasts cultured on the acellular dermal matrix may play a role in regenerating the periodontal ligament-like tissue with new cememtum-like tissue formation.

      • KCI등재

        Multiparametric magnetic resonance imaging for prostate cancer: A review and update for urologists

        유상준,김정곤,정인갑 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.7

        Recently, imaging of prostate cancer has greatly advanced since the introduction of multiparametric magnetic resonance imaging (mpMRI). mpMRI consists of T2-weighted sequences combined with several functional sequences including diffusion-weighted imaging, dynamic contrast-enhanced imaging, and/or magnetic resonance spectroscopy imaging. Interest has been growing in mpMRI because no single MRI sequence adequately detects and characterizes prostate cancer. During the last decade, the role of mpMRI has been expanded in prostate cancer detection, staging, and targeting or guiding prostate biopsy. Recently, mpMRI has been used to assess prostate cancer aggressiveness and to identify anteriorly located tumors before and during active surveillance. Moreover, recent studies have reported that mpMRI is a reliable imaging modality for detecting local recurrence after radical prostatectomy or external beam radiation therapy. In this regard, some urologic clinical practice guidelines recommended the use of mpMRI in the diagnosis and management of prostate cancer. Because mpMRI is the evolving reference standard imaging modality for prostate cancer, urologists should acquire cutting-edge knowledge about mpMRI. In this article, we review the literature on the use of mpMRI in urologic practice and provide a brief description of techniques. More specifically, we state the role of mpMRI in prostate biopsy, active surveillance, high-risk prostate cancer, and detection of recurrence after radical prostatectomy.

      • KCI등재

        세라믹막(MF) 고도정수처리에서 NOM 제거 특성

        유상준,박성한,임재림,서정민,장성호,홍성철,이병인 대한상하수도학회 2014 상하수도학회지 Vol.28 No.4

        This study assessed the removal efficiency of NOM which is known as the precursors of DBPs in advanced water treatment using the ceramic membrane filtration, introduced the first in the nation at the Y water treatment plant (WTP). It is generally well-known that the removal of NOM by MF Membrane is very low in water treatment process. But, the result of investigation on removal efficiency of NOM in advanced water treatment using the ceramic membrane was different as follows. The removal rate of organic contaminant by the ceramic membrane advanced water treatment was determined to be 65.5% for the DOC, 85.8% for UV254, and 77 to 86% for DBPFP. The removal rate of pre-ozonation was found to be 6 to 15% more effective compared with the pre-chlorination. The removal rate of DOC and UV254 in biological activated carbon(BAC) process was over 50% and 75%, respectively although the rate was decreased 10 ~ 20% according to analysis items in converting from GAC to BAC.

      • KCI등재

        부산 기장에서 채집된 말미잘의 분자생물학적 방법을 이용한 동정

        유상준,김도형,Yoo, Sang Joon,Kim, Do-Hyung 한국수산과학회 2017 한국수산과학회지 Vol.50 No.4

        In this study, we tried to identify a sea anemone collected from the coast of Gijang, Busan. The anemone was morphologically similar to species belonging to the genus Anthopleura, but its morphological characteristics did not allow for confirmed identification to species level. Multiple genes from mitochondrial cytochrome oxidase III, 12S and 16S rRNA, and nuclear 18S and 28S rRNA, were amplified for multilocus sequence typing (MLST) analysis using genomic DNA extracted from the sampled anemone and a different primer set. Based on the MLST analysis, the anemone obtained in this study was identified as Anthopleura artemisia. Also, the sequence of internal transcribed spacer-2 was most closely related to A. artemisia, indicating that this single region might be useful for anemone identification. This study shows significance of molecular identification for sea anemones, and will be helpful in studies of sea anemone identification using genotyping-by-sequencing.

      • KCI등재

        Y 정수장 세라믹막 여과공정 최적 운영인자 평가

        유상준,안효연,박성한,임재림,홍성철,이병인 한국막학회 2014 멤브레인 Vol.24 No.3

        본 연구는 국내 최초로 도입된 Y 정수장의 세라믹막 고도정수처리를 위한 최적 운영 인자를 도출하기 위하여 수행되었다. 경제성과 수질조건을 만족하면서도 세라믹막 여과성능을 지속⋅유지할 수 있는 최적 운영조건을 도출한 결과, Y 정수장의 평상시 수질 조건에서 막역세척으로 인한 배출수 발생량을 최소화시키면서도 막여과성능을 유지할 수 있는 최적 여과지속시간(역세척 주기)은 시설용량(16,000 m3/일) 기준 시 4.0시간으로 조사되었다. 또한 화학세척(CIP)에 따른 막차압 회복력을 조사한 결과, 구연산을 이용한 산세정을 통하여 철, 망간, 알루미늄 등의 막 파울링을 일으키는 무기오염물질은 제거되지만 막 회복률은 낮았다. 반면 차아염소산나트륨을 사용한 알칼리 세정을 통해서는 막 운영 초기 막차압으로 회복되는 것으로 나타났다. 막차압을 발생시키는 파울링 주요 원인물질은 친수성 고분자 유기오염물인 polysaccharides로 조사되었으며, 화학세척(CIP)시 막성능 회복률은 세척약품 온도에 의한 영향이 매우 크며, 온도가 높은수록 막성능 회복률이 향상되는 것으로 조사되었다. This study was performed to discover the optimum operation conditions for the advanced water treatment us-ing the ceramic membrane, introduced the first in the nation at the Y water treatment plant (WTP). The result of inves-tigation to find the optimum operation conditions which can continue preserving the filtration performance as well as satisfy-ing both the economics and the water quality is as follows. In the ordinary water quality condition of the Y WTP, the opti-mum filtration time(the backwash period), which can minimize the production of backwash waste and preserve the mem-brane performance was examined to be 4.0 hours on basis of institution capacity (16,000 m3/day). Examining the recovery rate of TMP from the chemical cleaning (CIP) discovered that the inorganic contaminants, which cause membrane fouling, such as iron, manganese, aluminum, were removed through the acidic cleaning using citric acid, whereas the membrane re-covery rate was found to be low. But, on the other hand, the TMP was recovered to the initial value from the alkali clean-ing using the NaOCl. Therefore, the main contaminant causing the fouling was determined to be hydrophilic organic com-pound(biopolymer). The membrane recovery rate is highly influenced by the temperature of the cleaning chemical. That is, the rate increased with increasing temperature.

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