Dorsal Epidural Migration of Lumbar Sequestered Disc Fragment: Report of Three Cases

위성현,정선관,심대무 대한영상의학회 2014 대한영상의학회지 Vol.71 No.1

Herein we report three cases of dorsal epidural migration of sequestered lumbar disc fragment in male patients older than 60 years. One of the patients underwent a microscopic decompression and discectomy for a herniated lumbar intervertebral disc disease five months ago. The magnetic resonance imaging showed characteristic features of dorsal epidural migration of a sequestered lumbar disc fragment. We suggest that both, older age and previous intervertebral decompression surgery may be the predisposing factors for the dorsal epidural migration of the sequestered lumbar disc fragment.

십자와 적록 조합시표를 이용한 노안 가입도 측정

위성현,문병연,유동식 한국안광학회 2008 한국안광학회지 Vol.13 No.4

Purpose: To compare the tentative and final addition, a combination chart of cross-grid and red green with the final addition prescribed in presbyopia were used in this study. Methods: The study subjects were 60 persons with presbyopia who were 41 to 60 years (mean: 51.7 years). Tentative addition were determined using red green chart (RG), cross-grid chart (CG) and the combination chart (red green cross-grid chart, RGCG) of the above two. And the final addition for a 40 cm working distance was determined for each subject by adjusting the tentative addition. Results: It was found that there were statistically significant differences of the final addition and the tentative addition between the each different test method. This result indicated that using the red-green cross-grid chart is the higher repeatability. Conclusions: This study shows that red green cross-grid chart (RGCG) seems to be get proper data for determining addition in presbyopes, and this method would be helpful in the diagnostic evaluation of addition in binocular vision testing. 목적: 노안에서 십자와 적록을 조합한 시표를 사용하여 얻어진 잠정가입도와 최종가입도를 비교하기 위해 실시하 였다. 방법: 대상자는 41~60세(평균연령 51.7세) 사이의 노안이 있는 60명으로 하였다. 잠정가입도는 십자시표(CG), 적록시표(RG) 및 두 가지 시표를 조합하여 만든 적록십자시표(RGCG)를 사용하여 결정하였으며, 최종가입도는 검 사거리 40cm에서 각 대상자에 맞게 잠정가입도를 조정하여 결정하였다. 결과: 측정 방법별 잠정가입도와 최종가입 도 사이의 유의한 차이가 있었으며, 적록십자시표에 의한 방법이 높은 신뢰도(repeatability)를 나타냈다. 결론: 적록 십자시표(RGCG)는 노안 가입도 결정에 필요한 적절한 데이터를 얻을 수 있으며, 양안시 임상에서 가입도 처방의 진단 평가에 유용할 것이다.

병원 내 환자에서 분리한 Klebsiella pneumoniae에서 광범위 β-lactamase의 분자생물학적 특성

위성현,김수영,김상일,김양리,유진홍,신완식,강문원 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.2

Intracortical Chondroma: A Case Report

위성현,정선관,최금하,윤권하,박성훈,김혜원 대한영상의학회 2015 대한영상의학회지 Vol.72 No.1

Herein we report a rare case of an intracortical chondroma with the histologic appearance of an enchondroma but located within the cortical bone.

Bicortical Screw Purchase at Upper Instrumented Vertebra (UIV) Can Cause UIV Fracture After Adult Spinal Deformity Surgery: A Finite Element Analysis Study

위성현,현승재,Bok-Ku Kang,김기정,장태안,김현집 대한척추신경외과학회 2020 Neurospine Vol.17 No.2

Objective: To examine the biomechanical stress distribution at the upper instrumented vertebra (UIV) according to unicortical- and bicortical purchase model by finite element analysis (FEA). Methods: A T8 to Sacrum with implant finite element model was developed and validated. The pedicle screws were unicortically or bicortically inserted from T10 to L5, and each model was compared and the von Mises (VM) yield stress of T10 was calculated. According to the motion (flexion, extension, lateral bending, and axial rotation) of spine, boundary condition values were set as 15°, 15°, 10°, 4°. Results: Although the 2 stress values did not show a significant difference between the unicortical- and bicortical purchase models in the flexion and extension, bicortical purchase model showed a larger stress distribution. However, the asymmetric behavior was significantly greater in the case of lateral bending (0.802 MPa vs. 0.489 MPa) and the rotation (5.545 MPa vs. 4.905 MPa). The greater stress was observed on the spinal body surface abutting the implanted screw. Although the maximum stress was observed around the implanted screw in the bicortical purchase model under axial loading, the VM stress of both models was not significantly different. Conclusion: Bicortical purchase model showed a larger stress distribution than the unicortical model, especially in the case of lateral bending and the rotation behavior. Our biomechanical simulation by FEA indicates that bicortical fixation at UIV can be a risk factor for early UIV compression fracture after adult spinal deformity surgery.

COVID-19 백신 접종 후 나타나는 눈의 기능 변화

위성현,조현국,유동식,김상엽,오성진,문병연 한국안광학회 2022 한국안광학회지 Vol.27 No.1

목적: COVID-19 백신 접종이 눈에 미치는 영향을 알아보고자 하였다. 방법: 36명의 보건의료인(평균 연령 32.86±8.35세)을 대상으로 COVID-19 백신 접종 1일, 1주, 2주, 3주 경과 후 굴절이상도, 사위도, 조절력, 안압, 동공 크기, 각막 두께, 안축 길이를 측정하여 백신 접종 전과 비교하였다. 결과: 백신 접종 후 조절력 저하를 호소한 경우가 36명 중 4명(11.11%), 흐린 시력을 호소한 경우는 36명 중 3명(8.33%)이었다. 백신 접종과 안구성분의 연관성은 없었으며 조절력은 접종 1일 후부터 감소하였다가 2주 후부터 서서히 회복되는 경향을 보였다. 결론: 대상자의 10% 정도에서 백신 접종 후 일시적인 조절력 저하로 인하여 근거리를 볼 때 불편함을 호소하는 것을 확인할 수 있었다. 안경사는 일부 접종자에게 일시적 조절장애로 급격한 근거리 시력장애가 나타날 수 있음을 유념해야 할 것이다. 백신 접종자들에 대한 지속적인 모니터링을 통해 눈에 나타날 수 있는 부작용에 대한 사례들을 수집하여 임상에서 굴절검사 시 정확한 처방에 활용할 수 있도록 백신 부작용에 대한 공유시스템을 통한 교육 및 홍보가 필요할 것으로 보인다.

조직 이식에서 감염원의 선별

위성현,강문원 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.2

신장이식 환자에서 거대세포바이러스 감염의 조기 검색을 위한 반정량적 중합효소 연쇄 반응 및 면역세포화학적방법의 이용

위성현,김양리,최정현,유진홍,양철우,신완식,방병기,강문원 대한감염학회 1996 감염 Vol.28 No.2

목적: 저자들은 장기 이식후 면역기능이 저하된 환자들에서 CMV감염의 조기 검색을 위한 반정량적 중합효소 연쇄반응 및 CMV 항원혈증검사의 임상적 이용 가능성을 알아보고자 신수여자를 대상으로 신장이식전 및 이식후 혈액을 채취하여 이 두 가지의 검사를 함께 시행하여 결과를 비교하였다. 방법: 가톨릭대학교 의과대학 부속병원에서 1995년 1월부터 7월까지 신장이식을 받은 환자 28명으로부터 신이식 전과 신이식 후 12주까지 채취된 187개 혈액에서 반정량적 중합효소 연쇄반응 및 CMV 항원혈증검사를 시행하였다. 결과: 1) 중합효소 연쇄반응 검사상 신수여자 12명(42.9%)에서, 항원혈증 검사상 신수여자 13명(46.4%)에서 CMV감염을 보였다. 2) 187개 혈액중 중합효소 연쇄반응 검사상 양성을 보인 경우는 30개(16%)였고, 항원혈증 검사상 양성을 보인 경우는 34개(18.2%)였다. 3) 중합효소 연쇄반응 검사상 양성을 보인 30개 혈액중 28개(93.3%)가 항원혈증 검사상 양성이었고, 중합효소 연쇄반응 검사사에서 음성을 보인 157개 혈액중 151개(96.2%)가 항원혈증 검사상 음성이었다. 4) 중합효소 연쇄반응에서 많은 양의 CMV DNA가 검출된 군에서 항원양성 세포수도 더 높게 나타났다. 5) 혈청학적 검사를 함께 시행하였던 115개 혈액중 중합효소 연쇄반응 양성인 혈액 20개중 3개 (15%)에서만 혈청학적검사로 CMV감염이 진단되었다. 결론: 혈청학적 검사 등 기존의 방법에 비해 반정량적 중합효소 연쇄반응과 CMV 항원혈증 검사법이 임상증세가 없는 CMV 감염의 조기 검색에 매우 유용할 것으로 사료된다. Background: Cytomegalovirus(CMV) attacks about 35% of kidney transplant recipients. and is reported to be the direct cause of death in 2% of renal transplant recipients. The most specific diagnostic method for CMV infection is isolation of the virus by culture. However, viral culture takes too much time to detect CMV infection and CMV antibody titers may not be elevated among immunocompromised patients. Therefore, rapid and sensitive methods for detection of CMV viremia are required. Semiquantitative polymerase chain reaction(PCR) and antigenemia assay can be used for rapid diagnosis of CMV viremia. Methods: We performed a prospective study using semiquantitative PCR and antigenemia assay for rapid detection of CMV viremia in 187 blood specimens from 28 renal transplant recipients at weekly or biweekly interval for 3 months after transplantation. Results: 1) PCR assay was positive in 12(42.9%) and CMV antigenemia was noted in 13(46.4%) out of 28 renal transplant recipients during 3 month period after transplantation. 2) Out of 187 specimens, 30(16%) were positive by the PCR assay and 34(18.2%) were positive by the CMV antigenemia assay. 3) Twenty eight(93.3%) of 30 PCR-positive specimens were positive by CMV antigenemia assay and 151(96.2%) of 157 PCR-negative specimens were negative by CMV antigenemia assay. 4) CMV DNA levels were significantly associated with CMV antigen-positive cells. 5) Serologic tests also were performed in 115 of 187 specimens. Among 20 PCR positive from 9 recipients, only 3 from 2 recipients were positive by serologic test using ELISA method. Among 95 PCR-negative specimens from 22 recipients, 4 specimens from 2 recipients were positive by the serologic test. Conclusion: These results suggest that semiquantitative PCR and the CMV antigenemia assay be useful for early detection of CMV infection in patients with renal transplantation.

COVID-19 백신 접종 후 추적 관찰을 통한 시기능 평가

위성현(Sung-Hyun Wee),조현국(Hyun Gug Cho),유동식(Dong-Sik Yu),김상엽(Sang-Yeob Kim),문병연(Byeong-Yeon Moon) 한국안광학회 2022 한국안광학회지 Vol.27 No.3

결핵성 척추염 10례의 수술적 치료에 관한 임상적 고찰

위성목,어환,남도현,이정일,김종수,홍승철,신형진,박관,김종현,Whee, Sung Mock,Eoh, Whan,Nam, Do Hyun,Lee, Jung Il,Kim, Jong Soo,Hong, Seung-Chyul,Shin, Hyung Jin,Park, Kwan,Kim, Jong-Hyun 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.11

Objects : Because of the nonspecific nature of symptoms in tuberculous spondylitis, a delay in the diagnosis can result in progressive neurologic deficits. The authors evaluate the clinical and the radiological results of the 10 cases of surgically treated tuberculous spondylitis. Clinical materials & Methods : We retrospectively analyzed the medical records of 10 patients with tuberculous spondylitis who were treated between February 1996 and March 2000. Six patients were female, and four were male. Mean age was 43 years old, and mean follow-up period was 20.5 months. All patients were treated with 12 months of antituberculous medication postoperatively, and were followed by complete blood count, ESR, spine X-ray and MRI. Results : The lumbar spine was involved in 5 patients, the thoracic in 4, and the thoracolumbar in one. The infected vertebral bodies were 2.8 in average. The associated lesions were pulmonary tuberculosis in 3 cases, and renal tuberculosis in one. Five patients were treated by anterior debridement and fusion with bone graft using anterior instrumentation, 2 with anterior debridement and fusion with bone graft(Hong Kong procedure only), 1 with Hong Kong procedure with posterior spinal instrumentation, and 2 were managed with posterior debridement and posterior spinal instrumentation. All patients improved after operation, and the average kyphotic angle decreased postoperatively. Postoperatively, one patient had a fistula at the operative site. Conclusion : The debridement and minimal level fusion of motion segment with instrument fixation is one of surgical option for tuberculous spondyltis to preserve the spine motion segment as much as possible. Spine instability and kyphosis were prevented by anterior and posterior spinal instrumentation. But, large number of cases and longer period follow-up study in future will be needed to confirm the long term results.