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Relationship between diet composition and the fecundity of Musca domestica
원란,권오석 한국곤충학회 2009 Entomological Research Vol.39 No.6
A study of the relationship between diet compositions of housefly Musca domestica and the fecundity of the insect was carried out. Fecundity was increased more than 30% by adding a protein source and inorganic salts into the larval and adult diets. Also, adding a protein source into the adult diet prolonged the oviposition period of adult houseflies.
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원란 한국키틴키토산학회 2017 한국키틴키토산학회지 Vol.22 No.4
Chitin is one of the critical components which are mainly existing in insect exoskeleton, crustacean shells (crab, shrimp and krill) and even fungi cell wall. Researchers in the world have intensively investigated on chitin and chitosan due to its potential value to develop diverse products ranging from biofertilizers for plant growth to therapeutic agents optimized for human and animal health improvement. In case of Korea, it has been reported that chitin and chitosan have been isolated and biochemically characterized from Musca domestica, Periplaneta americana, Gryllus bimaculatus and Tenebrio molitor. In addition, the technology that chitin monomer (N-acetyl-glucosamine) can be generated from mealworm chitin by using chitinase derived from microorganism has been established and thus will be useful for future application in insect industry in Korea. In other countries, various insects including grasshopper, silkworm, fly and beetle have been used as resources for producing chitin. The chitosan obtained after deacetylation of chitin has been tested for biomedical application with therapeutic purposes in other countries. In conclusion, insect-based chitin research and development for producing diverse products will be essential for activating insect industry and its related pet industry in Korea.
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원란 한국키틴키토산학회 2019 한국키틴키토산학회지 Vol.24 No.2
Insects have large numbers of individuals, short generations, good breeding ability, and short breeding periods. Because of small body size, it is not necessary to take much of the space and labor for breeding. Therefore environmentally friendly cultivation and mass production are possible. Insects can synthesize and decompose chitin continuously during the life cycle. Because insects have low level of inorganic materials, the acidic treatment used for extracting procedure from insects are moderate in general. Instead of cultivated insect, even insects which can be harmful in agriculture and traffic in urban life might be utilized as an alternative chitin source for application of valuable scope. All insect-derived chitin studied was the most stable structure, α-chitin, and the characteristics related to solubility, molecular weight, degree of deacetylation, ash content, and moisture content were more suitable for various application. Insect-derived chitosan showed high antibacterial, antioxidant and antitumor activities and exhibited biological properties such as the effect of accelerating wound healing and inhibiting the growth of fungi. Therefore, this review article intends to suggest the possibility that insect - derived polysaccharides can be used as a valuable natural resource to replace chitin and chitosan derived from crustaceans.
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원란(Ran Won) 대한스트레스학회 2013 스트레스硏究 Vol.21 No.3
주요우울장애는 여성에서 남성에 비해 두 배나 높은 발병률을 나타낸다. 주요우울장애의 성에 따른 차이점을 밝히기 위해 생물학적 요인들에 대한 많은 연구가 진행되었다. 이 논문에서는 주요우울장애의 발병률에 영향을 미치는 성의 차이점을 생리학적, 해부학적 견지에서 살펴보았다. 아직까지 더 연구되고 검증되어야 할 많은 문제들이 있지만 이러한 시도는 주요우울장애의 효과적인 치료제를 개발하기 위해서 성의 차이점을 고려하여야 한다는 개념을 제시해 줄 수 있을 것이라 사료된다. The prevalence of major depressive disorder (MDD) is twice as common in women as in men. A lot of biological evidences are identified to clarify the gender specific background of MDD. This review examines some potentials factors contributing to the sex difference for incidence rate of MDD in terms of physiological and anatomical response. Although further researches have to be carried out and many problems to be resolved, these approaches suggest that gender specific differences have to be considered in drug development for MDD.
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원란(Ran Won) 대한스트레스학회 2012 스트레스硏究 Vol.20 No.4
주요우울장애는 매우 복잡한 유전양식을 가지며 유전과 환경의 영향을 동시에 받는 질환이다. 많은 연구들을 통해 말초에 존재하는 성장인자, 염증관련 인자, 내분비관련인자 및 대사관련 인자들의 발현수준이 주요우울장애에서 변화하며 항우울제를 처치하였을 때 회복된다는 것이 밝혀졌다. 또한 주요우울장애와 관련된 유전자의 부위나 대립유전자들이 밝혀졌다. 아직까지 더 연구되고 검증되어야 할 많은 문제들이 있지만 생물표지자에 대한 많은 정보는 주요우울장애에 대한 진단, 치료 및 병인의 연구에 새로운 방향을 제시해줄 수 있을 것이다. Major depressive disorder (MDD) is a genetically complicated disease and modulated by environment. A lot of mounting evidence suggests that circulating levels of peripheral biomarkers including growth factors, inflammatory cytokines, endocrine factors, and metabolic factors are changed and reversed by antidepressants in a state of MDD. Many studies identified specific region of genes and contributable alleles for MDD expression. Although there are many problems to be resolved, these approaches based on gene interaction and biological analysis suggest new and perspective investigation of diagnosis, treatment, and pathophysiology of MDD.
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Characterization of Invertase in Cabbage white butterfly, Pieris rapae L.
Won, Ran,Han, Weon Dong,Kim, Hak Ryul 순천대학교 기초과학연구소 1990 基礎科學硏究誌 Vol.1 No.-
배추흰나비(Pieris rapae L.)의 invertase를 分離, 精製하여 isozyme의 存在與否, 物理化學的 特性, 變態段階에 따른 活性變化 및 器管別 分布 등을 조사하여 다음과 같은 結果를 얻었다. 1. Invertase는 3個의 isozyme이 存在하며, enzyme 1은 分子量이 252K, enzyme 2는 110K, enzyme 3는 60K이었다. 또한 3個의 isozyme의 等電點(pI)는 각각 4.32, 5.93, 6.15로 측정되었다. 2. 각 isozyme의 物理化學的 特性을 조사한 결과, 3個의 isozyme들은 모두 pH 5.5, 37℃에서 最大의 活性을 보이며, enzyme 1의 km값은 2.1×10^-3M, enzyme 2의 km값은 20 ×10^-3, enzyme 3가 가장 불안정한 것으로 나타났다. 3.變態段階에 따른 酵素活性의 변화에 있어서, 3개의 isozyme 모두가 5齡末期까지 最大活性을 보이다가, 용時期에 점차로 消失된 후 成蟲에서 다시 높은 活性을 나타내었다. 4. 器管別 分布를 조사한 結果, 前腸과 中腸에는 3個의 isozyme이 모두 존해하며, 後腸과 혈림프에는 enzyme 3만이 존재하였고, 脂肪體와 침샘에는 존재하지 않는 것으로 나타났다. Invertase of cabbage white butterfly, Pieris rapae L. was isolated and purified to determine the localization, physicochemical properties, changes of activities with developmental stages and organ distribution of its isozymes. 1. Invertase consists of three isozymes with M.W. 250 kd for enzyme 1,110 kd for enzyme 2 and 60 kd for enzyme 3.pI values of three isozymes are 4.32, 5.93 and 6.15, respectively. 2. The pH optimum of three isozymes is 5.5 and optimal temperature is 37℃. Km value of each isozyme is 2.1×10^-3M for enzyme 1,20×10^-3M for enzyme 2 and 15.9×10^-3M for enzyme 3. Heat stability of the isozymes 1 and enzyme 2 is more stable than enzyme 3. 3. All of each isozymic activity shows a high in late 5th instar larval stges, and gradually decrease in pupal period. During adult stage, the activity shows a drastic increase. 4. Three isozymes of invertase were found in foregut and midgut, but were not in fat body and salivary gland. In hindgut and haemolymph, only enzyme 3 was found.
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