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Hypothyroidism is a common disease of the endocrinal system, characterized by fatigue, cold intolerance, bradycardia, and so on. Subclinical hypothyroidism is a common biochemical abnormality which can be found in routine screening tests of thyroid function. It is defined as an asymptomatic state which characterized by normal free thyroxine(FT4) and elevated thyroid stimulating hormone(TSH) levels. The purpose of this study was to evaluate the effect of treatment with palmijihwang-tang and to observe the changes in triiodothyronine(T3), free thyroxine(FT4), thyroid stimulating hormone(TSH) level and VAS of cold intolerance, hoarseness, dry skin. After the treatment, triiodothyronine(T3) increased from 57.12ng/dl to 120.53ng/dl. Free thyroxine(FT4) increased from 12.59pg/ml to 14.21pg/ml. Thyroid stimulating hormone(TSH) decreased from 10.61mU/L to 1.57mU/L. Cold intolerance, hoarseness and dry skin changed for the better. These results support a role for oriental medical therapy in treating subclinical hypothyroidism. Further case studies of herbal treatment of this ailment are needed.
Hyperlipidemia is one of the major factors causing the atherosclerosis of coronary arteries and a well-documented modifiable risk factor for stroke, especially of the ischemic type. Constipation is the condition of being unable to empty the bowels frequently enough or effectively. However, it is usually temporary and not a serious disease. Salicornia herbacea is a sea coast plant that grows on the western and southern coastal beaches and salt flats of the Korean peninsula. Belonging to Chenopodiaceae by biological classification. Salicornia herbacea is not known from research except that it contains plenty of minerals. The purpose of this study was to evaluate the effect of treatment with Hamcho-hwanand to observe changes in total cholesterol (T-Chol) high-density lipoprotein cholesterol (HDL), triglyceride (TG) and constipation. After treatment, total cholesterol decreased from 273mg/dl to 235mg/dl. Triglyceride decreased from 201mg/dl to 126mg/dl. HDL cholesterol increased from 30mg/dl to 40mg/dl. Constipation changed for the better. These results support a role for oriental medical therapy in treating hyperlipidemia and constipation. Further case studies of herbal treatment of this ailment are needed.
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본 연구는 유단백질에 단백질 분해효소를 처리하여 가수분해 후 저분자 peptide를 ABTS법을 이용하여 항산화 활성을 측정하여 유단백질 유래 저분자 peptide의 항산화력을 측정하고자 하였다. Chymotrypsin 처리한 유청단백질의 가수분해도가 가장 높았으며, 유청단백질의 락트알부민 및 락토글로브린이 분해되어 분자량 20 kDa 이하의 저분자 단백질이 생성된 것을 전기영동을 통하여 확인하였다. 유단백질의 농도에 따른 항산화 활성을 측정한 결과, 카제인의 항산화 활성이 유청단백질보다 높게 나타났다. 유단백질을 효소에 의하여 가수분해 시 항산화 활성이 증가하였으며, 카제인 가수분해물이 유청단백질 가수분해물과 비교하여 항산화 활성이 더 높았으나, 가수분해도와 항산화 활성도의 관계는 일치하지 않았다. Trypsin에 의한 카제인 가수분해 물의 항산화 활성이 80.7%로 가장 높았다. 본 연구에서는 chymotrypsin과 trypsin에 의한 분자량 3 kDa의 카제인 분획물의 항산화 활성이 가장 우수 하였으며, 유청단백질을 trypsin으로 분해하였을 때 항산화 활성이 증가하였다. The principal objective of the current study was to prepare low molecular weight peptides from milk proteins using enzymatic hydrolysis techniques, in an effort to assess the antioxidant activity of these peptides. The casein and whey proteins isolated from fresh milk were treated with several proteolytic enzymes, such as chymotrypsin, pepsin, and trypsin and the resulting low molecular weight peptides were collected by TCA precipitation. Their identity was confirmed by SDS-PAGE analysis. The hydrolysis experiments indicated that whey protein treated with chymotrypsin displayed the highest degree of protein hydrolysis. The antioxidant activity of milk protein hydrolysates was determined by measuring the ABTS-radical scavenging activity. The results of these experiments showed that hydrolysis of the milk protein was effective in increasing their antioxidant activities. Especially, the tryptic digested casein displayed the highest radical scavenging activity (80.7%). The hydrolyzed low molecular weight milk protein was isolated using an ultrafiltration membrane. The casein hydrolysate passed through a membrane with molecular weight cut-off (MWCO) of 3 kDa displayed the strongest antioxidant activity.
본 논문에서는 CRCW(Concurrent Read Concurrent Write)와 CREW(Concurrent Read Exclusive Write) PRAM(Parallel Random Access Machine) 모델에서 무방향성 그래프 G=(V, E)의 극대 매칭을 구하기 위해 간결한 랜덤 병렬 알고리즘을 제안한다. CRCW PRAM 모델에서 m개의 선을 가진 그래프에 대해, 제안된 매칭 알고리즘은 m개의 프로세서 상에서 O(logm)의 기대 수행 시간을 가진다. 또한 CRCW 알고리즘을 CREW PRAM 모델에서 구현한 CREW 알고리즘은O(log²m)의 기대 수행 시간을 가지지만, O(m/logm) 개의 프로세서만을 가지고 수행될 수 있다. This paper presents simple randomized parallel algorithms for finding a maximal matching in an undirected graph G=(V, E) for the CRCW and CREW PRAM models. The algorithm for the CRCW model has O(logm) expected running time using m processors, where m is the number of edges in G We also show that the CRCW algorithm can be implemented on a CREW PRAM. The CREW algorithm runs in O(log²m) expected time, but it requires only O(m/logm) processors.
Does snow depth initialization have a quantitative impact on sub-seasonal to seasonal prediction skill? To answer this question, a snow depth initialization technique for seasonal forecast system has been implemented and the impact of the initialization on the seasonal forecast of surface air tempreature during the wintertime is examined. Since the snow depth observation can not be directly used in the model simulation due to the large systematic bias and much smaller model variability, an anomaly resacling method to the snow depth initialization is applied. Snow depth in the model is initialized by adding a rescaled snow depth observation anomaly to the model snow depth climatology. A suite of seasonal forecast is performed for each year in recent 12 years (1999-2010) with and without the snow depth initialization to evaluate the performance of the developed technique. The results show that the seasonal forecast of surface air temperature over East Asian region sensitively depends on the initial snow depth anomaly over the region. However, the sensitivity shows large differences for different timing of the initialization and forecast lead time. Especially, the snow depth anomaly initialized in the late winter (Mar. 1) is the most effective in modulating the surface air temperature anomaly after one month. The real predictability gained by the snow depth initialization is also examined from the comparison with observation. The gain of the real predictability os generally small except for the forecasting experiment in the early winter (Nov. 1), which shows some skillful forecasts. Implications of these results and future directions for further development are discussed.
Recently, the urban street is not recognized as the space of the moving, but as the space of the people’s communication and open by a variety of the efforts like the naming of the cultural street. The signboard, which is like the visual pollution, is reorganized and the street is changed by burying the electric lines, and it is for the artistic desire to be satisfied expressing the local stagnation characteristically using the street furniture. In addition, the local specialty has created by the several festivals and events and it is remembered to the participants as the special meaning place. It is expected for the value of this kind of the street culture to be the place of the street, the expansion of the cultural approaches, the diffusion of the identity, local resuscitation and reconstruction, and the job creation. In this study, I would like to apply the ubiquitous concept to the space of the street for the activation of the street culture. The ubiquitous concept is the fusion place of the cyber space which is based on the information-telecommunication beyond the limitation of planning for the physical space object. The ubiquitous space is not only the connection and communication place among people as the original function of the city, but also the connection and communication place between the people and the thing and between the things. The ubiquitous space, which is intelligent by the urban consisted things and real time connection between the people, is more convenient, effective, and emotional comparing to the conventional city. As it is mentioned above, many studies have been done for the very comprehensive and complex space. In this study, the object is to define and create the cultural street which is applied by the ubiquitous concept for the activation of the street culture.
The element of the civic size is much more emphasized than that of the past national size in competitiveness of the information society and knowledge based society like today. It is for the beautiful and fresh civic creation like the civic size industry, historical culture, and environment to be the competitiveness. Expecially, the city of elegant and specialized space is a role of enhancing the quality of the city than any other area. Recently, Seoul is decided as the capital of the world design in ICSID held on San Francisco at 2007. It is an opportunity for the Seoul to leap as the design city which made a miracle of the Han River as the industrial city. However, the local history, the local history, the axis of the traditional time, the axis of the space, and the direction of the local development are deficient, because the public design business is progressed in very short term and at improvising which has been done in local government. It is impossible for people to take part in actively and it is fallen down for the city to make a sustainable possibility. In this paper, I would like to find out how to make the local identity and help the local activity. It is suggested to make the fun, comfortable and playing street using the theme street by storytelling. Eventually, the object of this paper is to review the effectiveness of the method where the Itaewon of design Seoul street construction business is applied by the theme street of the storytelling.
분산 시스템에서 작업들간의 우선 순위(precedence relation)를 위해 방향성 비순환 그래프(Directed Acyclic Graph)로 표현된 병렬 프로그램을 스케쥴하는 문제는 제한된 경우를 제외하고는 NP-complete 문제로 알려져 있다[l]. 따라서 실제 시스템에서의 작업 스케쥴링을 위해 다양한 모델과 가정 하에서 휴리스틱에 기반을 둔 알고리즘들이 제안되어 왔다[2,3,4,5,6,7,8]. 분산 시스템은 프로세서들과 네트워크의 성질에 따라 크게 동기종 분산 시스템(Distributed Homogeneous System)과 이기종 분산 시스템(Distributed Heterogeneous System)으로 구분 될 수 있다. 본 논문에서는 분산 시스템의 일반적인 모델을 동기종 분산 시스템과 이기종 분산 시스템에 대해 정의하고, 정의된 분산 시스템들에서 작업 스케쥴링을 수행하는 유전자 스케쥴링 알고리즘(Genetic Scheduling Algorithms, GSA)을 제안한다. 동기종 분산 시스템과 이기종 분산 시스템에서의 작업 스케쥴링은 각 시스템의 상이한 성질 때문에 다른 문제로 간주되고 있다. 그러나 GSA는 유전자 알고리즘이 지닌 견고(robust)한 성질을 통해 분산 시스템의 변화에 따라 스케쥴링의 수행시에 고려해야 할 요인이 변하는 영향을 극복할 수 있다. 본 논문에서 제안된 GSA는 모의 실험을 통해서 동기종 시스템에서는 리스트 스케쥴링 알고리즘과, 이기종 분산 시스템에서는 OLROG(One-Level Reach-Out Greedy) 알고리즘과 성능을 비교 및 분석하였다. GSA는 다양한 환경에서 뛰여난 성능의 향상을 보여 주었다. Scheduling a directed acyclic graph (DAG) which represents the precedence relations of the tasks of a parallel program in a distributed computing system (DCS) is known as an NP-complete problem except for some special cases[l]. Many heuristic-based methods have been proposed under various models and assumptions[2,3,4,5,6,7,8]. A DCS can be classified into two types according to the characteristics of the processors on a network: a distributed homogeneous system(DHOS) and a distributed heterogeneous system(DHES). This paper defines a general model for a DHOS and a DHES and presents genetic scheduling algorithms(GSA) to solve the task scheduling problem in the defined distributed computing systems. Task scheduling problems in DHOS and DHES are regarded as different problems due to their diffenrent factors in the scheduling. But the innate robustness of GSA can overcome the different factors. The performances of our GSA are compared with the list scheduling algorithm [3,5] in a DHOS and with the one-level reach-out greedy algorithm (OLROG)  in a DHES. The GSA presented in this paper have shown better performance in most cases than other scheduling methods.
The decadal change in rainfall for Changma period over the South Korea in early-2000s is detected in this study. The Changma rainfall in P1 (1992~2002) decade is remarkably less than in P2 (2003~2013) decade. The much rainfall in P2 decade is associated with the increase of rainy day frequency during Changma period, including the frequent occurrences of rainy day with a intensity of 30 mm/day or more in P2 decade. This decadal change in the Changma rainfall is due to the decadal change of atmospheric circulation around the Korean Peninsula which affects the intensity and location of Changma rainfall. During P2 decade, the anomalous anti-cyclone over the south of the Korean Peninsula, which represents the expansion of the North Pacific high with warm and wet air mass toward East Asia, is stronger than in P1 decade. In addition, the upper level zonal wind and meridional gradient of low-level equivalent potential temperature in P2 decade is relatively strengthened over the northern part of the Korean Peninsula than in P1 decade, which corresponds with the intensification of meridional gradient between air mass related to the East Asian summer monsoon nearby the Korean Peninsula in P2 decade. The enhanced meridional gradient of atir mass during P2 decade is favorable condition for the intensification of Changma rainfall band and more Changma rainfall. The atmospheric conditions related to enhanced Changma rainfall during P2 decade is likely to be influenced by the teleconnection linked to the suppressed convection anomaly over the southern part of China and South China Sea in P2 decade.