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소아청소년 틱 장애(Tic disorder) 환자의 임상적 특성과 심리분석
우샛별,심영석,이건희,김성구 대한소아신경학회 2012 대한소아신경학회지 Vol.20 No.2
Purpose : Tic disorder is a neurodevelopmental disorder which begins in early childhood and continues into adolescence and adults. Tic disorder affects 1-2% of the population. In order to make a correct diagnosis and treatment of tic disorder, the clinical psychological analysis is needed because children with tic disorder tend to have higher rates of emotional and behavioral difficulties than those of the general population. The aim of this study was to evaluate the clinical and psychological characteristics of child with tic disorder. Methods : The sample consisted of 69 patients with tic disorder who visited to the pediatric neurology clinic of Kangnam sacred heart hospital from January 2007 to June 2010. Fifty patients who visited our clinic without tic disorder were included in the control group. Patients were classified as the DSM-IV, Tourette’s disorder, chronic motor or vocal tic disorder, tran- sient tic disorder and tic disorder not otherwise specified. Korean child behavior checklist (K-CBCL), K-WISC-III, ADS, K-ARS was conducted in the tic disorder patients and T score of K-CBCL was compared with the control group. Results : Male to female ratio was 2.5:1 in the study group and the mean age was 9.5±3.2 years old. The symptom period was 16.7±17.2 months at their first visit. Twelve subjects (18%) presented with Tourette syndrome, 14 subjects (20%) had multiple chronic motor or phonic tic disorder, 20 subjects (29%) had transient tic disorder and 23 subjects (33%) had tic disorder not otherwise specified. The Medications were given in 26 patients and risperidone was the primary drug for most of them. The mean T scores of K-CBCL were 55.5±6.1 for attention scale, 56.9±6.9 for anxiety-depression scale, 56.5±7.4 for withdrawn scale, 52.0±3.4 for emotional lability scale. All of them were higher than control group (P
QTc Prolongation after Ventricular Septal Defect Repair in Infants
한창우,우샛별,최재영,정조원,박영환,박한기,신홍주,김남균 대한심장학회 2013 Korean Circulation Journal Vol.43 No.12
Background and Objectives: Prolonging of the corrected QT interval (QTc) has been reported after cardiac surgery in some studies. However,there have not been many studies on infant open cardiac surgery for ventricular septal defect (VSD) repair. This study was performed to define the changes in QTc and to find related post-surgery factors in this patient group. Subjects and Methods: From 2008 to 2012, 154 infants underwent VSD repair at the Severance Cardiovascular Hospital. This study includes 105 of these cases. QTc was measured in these patients retrospectively. Demographic data and peri-procedural data, such as Aristotle score, cross-clamp time and bypass time, were analyzed. The exclusion criteria included multiple and small VSDs that underwent direct closure. Results: Mean post-operative QTc was increased compared to the pre-operative measurements (from 413.6±2.3 to 444.9±2.5, p<0.001). In multiple linear regression, the comprehensive Aristotle score was associated with increasing QTc (p=0.047). The incidence of transient arrhythmia, such as atrial tachycardia, junctional ectopic tachycardia, premature atrial contraction, or premature ventricular contraction,was associated with QTc prolongation (p=0.005). Prolonged QTc was also associated with cross-clamp time (p=0.008) and low weight (p=0.042). Total length of stay at the intensive care unit and intubation time after surgery were not associated with QTc prolongation. Conclusion: Prolonged QTc could be seen after VSD repair in infants. This phenomenon was associated with peri-procedural factors such as the Aristotle score and cross-clamp time. Patients with QTc prolongation after cardiac surgery had an increased tendency towards arrhythmogenicity in the post-operative period.
백재은,박수진,우샛별,최재영,정조원,김남균 대한심장학회 2014 Korean Circulation Journal Vol.44 No.1
Background and Objectives: The profile of infective endocarditis (IE) has changed and is now showing an increasing prevalence of IE among congenital heart disease (CHD) patients. We studied the change of clinical profiles of IE over the past 25 years in patients with CHD at a single institution. Subjects and Methods: We reviewed medical records retrospectively for 325 patients diagnosed with IE between January 1, 1987, and March 31, 2012. We analyzed and compared the differences in patient characteristics and outcomes between 1987-2000 (group A) and 2001-2012 (group B). Results: Over the 25-year period, 93 cases of IE in CHD patients were diagnosed (59 cases in group A and 34 cases in group B). Ventricular septal defect was the most common underlying cardiac disease observed during the entire period. The most common causative pathogen was Streptococcus in both groups. Group A contained 16 cases (27.1%) that had undergone cardiac surgery, whereas this number was 19 (55.8%) in group B. The number of patients who had undergone palliative care or surgery using prosthetic materials was higher among group B patients (p<0.001). Surgical procedures due to uncontrolled infection were performed in three cases in group A and 10 cases in group B. Conclusion: Infective endocarditis and CHD show a close correlation, and the profile of IE patients can change in line with an increase in the survival rate of patients with complex CHD and the improvement of surgical techniques. Ongoing reassessment and the systematic management of these patients is crucial in the prevention and treatment of IE.
게터용 Zr57V36Fe7합금의 수소 흡수특성에 미치는 산소농도의 영향
박제신 ( Je Shin Park ),우샛별 ( Saet Byul Woo ),서창열 ( Chang Youl Suh ),박미영 ( Mi Young Park ),심건주 ( Gun Choo Shim ),김원백 ( Won Baek Kim ) 대한금속재료학회 ( 구 대한금속학회 ) 2006 대한금속·재료학회지 Vol.44 No.5
The effects of the oxygen concentration on the hydrogen sorption properties of an NEG(non-evaporable getter) alloy, Zr(57)V(36)Fe7, were investigated. The desired level of the oxygen concentration was obtained by letting an argon gas with 2.98 vol% O2 flow through a tube furnace containing the alloy powder at 423 K for a predetermined time period. The sorption speed of the alloy decreased almost linearly with the increase of the oxygen concentration. The reason for this can be explained as follows: the activated metal surface area decreases with the increase of the oxygen concentration and the activation of the metal surface covered with oxygen requires more energy to remove it.