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Sesame Oil Attenuates Renal Oxidative Stress Induced by a High Fat Diet.
우민지,한성경,송영옥 한국식품영양과학회 2019 Preventive Nutrition and Food Science Vol.24 No.2
The antioxidative effects of the bioactive compounds enriched sesame oil (e.g. lignans and tocopherols) are well established. This study aims to elucidate whether sesame oil could reduce renal oxidative stress induced by a high fat diet (HFD). Mice received HFD for 12 weeks (n=7 per group), which was prepared by adding 20% (w/w) lard (lard group) or sesame oil (sesame group) to the chow diet, respectively. Compared with mice in the lard group, renal lipid levels of those in the sesame group were reduced, show by decreases in protein expression of enzymes involved in fatty acid synthesis (sterol regulatory element-binding protein-1 and acetyl coenzyme A carboxylase a) and an increase in β-oxidation (peroxisome proliferator-activated receptor a and carnitine palmitoyltransferase I) (P<0.05). In the sesame group, levels of peroxynitrite and thiobarbituric acid reactive substances were also reduced, whereas the level of glutathione was increased. In addition, there was elevated protein expression levels of antioxidant enzymes regulated by nuclear factor-like 2, such as superoxide dismutase, glutathione peroxidase, and glutathione S-transferase (P<0.05), and decreased expression for nuclear factor kappa B and cyclooxygenase 2 (P<0.05). These results suggest that sesame oil could ameliorate HFD-induced renal damage by suppressing oxidative stress and inflammation.
비만아동의 심리사회적 문제에 대한 신체상의 매개효과 및 인구학적 변인의 중재효과
우민지,이정윤 한국상담학회 2007 상담학연구 Vol.8 No.2
The purpose of this study was to explore psychosocial factors related to body image of obese children. This study investigated the differences of body image and psychosocial variables between obese children and normal weight children, the mediating effect of body image for the psychosocial problems and the moderating variables of the relation between obesity and body image. The participants were 916 elementary school students. Body image, self-esteem, depression, peer-relations, teacher-relations, school adjustment, parent's child-rearing attitude scale were administered. The results were as follows; high-grade obese children showed lower score for social self-esteem and peer-relations than normal weight children, and the satisfaction of body image was a mediating variable in these relationships. Obese children with negative body image showed lower self-esteem, higher depression, and had more difficulty on peer-relation and school adjustment than obese children with positive body image. The child-rearing attitude of father was a moderator in the relationship between obesity and body image. Therefore, negative self-image and the child-rearing attitude served as a mediator or moderator. These results implicated the importance of counseling intervention on body image of obese children and the parent's child-rearing attitudes. Keywords : Obese children, body image, mediating and moderating effects. 본 연구는 비만 아동의 신체상과 관련된 심리사회적 요인의 관계를 밝히기 위하여, 비만과 정상체중 아동 간에 신체상 및 심리사회적 변인의 차이를 알아보고, 비만아동의 심리사회적 문제에 대한 신체상의 매개효과를 검증하였다. 아울러 비만과 신체상의 관계를 중재하는 인구학적 변인을 검토하였다. 연구 대상은 초등학교 3~6학년 학생 916명이며, 신체상 척도, 자기존중감 척도, 우울 척도, 친구관계 척도, 교사관계 척도, 학교적응 척도, 양육태도 척도로 구성된 질문지를 사용하였다. 연구 결과, 첫째, 고학년 비만아동은 정상아동에 비해 사회적 자기존중감과 친구관계가 유의미하게 낮았으며, 신체상 만족수준은 이러한 관계를 매개하는 것으로 나타났다. 둘째, 부정적 신체상을 지닌 비만아동은 긍정적 신체상을 지닌 비만아동에 비해 자존감이 낮고 우울이 높으며 친구관계 및 학교적응에 어려움을 나타냈다. 셋째, 비만아동과 신체상의 관계를 중재하는 요인은 부의 양육태도로 나타났다. 따라서 부정적인 신체상과 양육태도는 비만아동의 심리사회적 문제를 매개 및 중재하는 요인으로 검증되었으며, 이러한 결과는 비만아동의 신체상과 부모의 양육태도에 대한 상담개입의 중요성을 시사하고 있다. 주요어 : 비만아동, 신체상, 매개효과, 중재효과
우민지,김미정,노정숙,박찬흠,송영옥 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
This study investigated the effect of kimchi on hepatic lipid metabolism and inflammatory response. Lowdensity lipoprotein receptor knockout mice fed high cholesterol diet (HCD) with an oral administration of kimchi methanol extracts (KME, 200 mg kg bw-1 day-1) or distilled water for 8 weeks (n = 10 per group). Compared with the control group, plasma and hepatic lipid concentrations were lower in the kimchi group (p\0.05), which was confirmed with hepatic histological examination by Oil Red O staining. Hepatic expressions for fatty acid synthesis were downregulated whereas those for beta-oxidation were upregulated in the kimchi group (p\0.05). Hepatic expressions for cholesterol synthesis were decreased but those for cholesterol export was increased in the kimchi group (p\0.05). Moreover, kimchi intake reduced expression for inflammatory cytokines (p\0.05). Kimchi exerted beneficial effects on HCD-induced hepatic damage by suppressing lipid synthesis and inflammation, and facilitating fatty acid oxidation and cholesterol excretion.
보육교사의 직무스트레스가 교사효능감에 미치는 영향 : 직업정체성과 동료교사협력의 이중매개효과
우민지,이상선,임민정 한국영유아교원교육학회 2023 유아교육학논집 Vol.27 No.1
This study aims to analyze the dual mediating effects of teachers’ professional identity and colleague collaboration in the relationship between job stress and teacher efficacy among childcare teachers. The subjects of the study were 705 childcare teachers. The collected data were analysed using descriptive statistics, independent sample t-test, ANOVA, person correlation analysis, and pathe analysis with SPSS 25 and AMOS 23 programs. The primary results of this study as follows: First, there was a correlation between job stress of childcare teachers, teacher efficacy, job identity and colleague collaboration. Second, childcare teachers’ job stress had an indirect effect on teacher efficacy through teachers’ colleague collaboration. Third, childcare teachers’ job stress had an indirect effect on teacher efficacy through teachers’ professional identity and colleague collaboration. This revealed the dual mediating effect of teachers’ professional identity and colleague collaboration in the relationship between job stress and teacher efficacy. The results suggest that job stress of childcare teachers should be reduced and teachers' professional identity and colleague collaboration should be increased to enhance teacher efficacy. The findings of this study will contribute to designing educational programs to improve childcare teacher’s efficacy. 본 연구에서는 보육교사 705명을 대상으로 보육교사의 직무스트레스가 교사효능감에 미치는 영향에서 직업정체성과 동료교사협력의 매개효과 및 이중매개효과를 살펴보고자 하였다. 분석을 위하여 SPSS 25와 AMOS 23을 활용하여 독립표본 t-test, ANOVA, 기술통계, 경로분석을 실시하였다. 연구결과로 첫째, 보육교사의 직무스트레스가 높을수록 직업정체성과 동료교사협력, 교사효능감은 낮아지는 부적 상관관계를 보였으며, 직업정체성, 동료교사협력, 교사효능감 간은 정적 상관관계를 보였다. 둘째, 보육교사의 직무스트레스와 교사효능감의 관계에서 직업정체성과 동료교사협력은 부분매개효과를 보였으며, 순차적 이중매개효과가 유의미하였다. 직무스트레스와 교사효능감의 관계에서 직업정체성이 우선 확립되고 순차적으로 동료교사협력이 발휘된다면 교사효능감은 더욱 높아짐을 시사한다.
A Case of Retinal Vessel Occlusion Caused by Bartonella Infection
우민지,안소민,송준영,김성우 대한의학회 2018 Journal of Korean medical science Vol.33 No.47
A 29-year-old female visited the emergency room with sudden visual loss in the right eye started on the same day. She had been suffering from fever for two days. A best-corrected visual acuity (BCVA) was 0.5/0.7 in the Snellen chart. Fundus examination (Fig. 1) showed multiple retinal hemorrhages. Severe vascular sheaths around the optic disc area were present in the right eye. Candle-wax-dripping sign in the superior hemisphere were found in the left eye.