http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
소간세포암에 대한 근치적 절제 후의 생존율 및 예후 결정인자
우광훈(Gwang Hoon Woo),윤정환(Jung Hwan Yoon),한철주(Chul Ju Han),이효석(Hyo Suk Lee),이건욱(Kun Wook Lee),김정룡(Chung Yong Kim) 대한내과학회 1997 대한내과학회지 Vol.53 No.5
N/A Background: The survival in patients with hepatocellular carcinoma (HCC) has recently been improved by the advancement in the early detection of HCC. Among the various treatment modalities, the surgical resection has been considered as the most effective for small HCC, and the clinical course of patients with small HCC who underwent curative resection is known to be dependent on the etiology of HCC. Since the differences in the etiology of HCC depend on the different geographical area, it is necessary to verify the clinical outcomes and their affecting factors in patients with small HCC after curative resection in Korea, one of the hepatitis- B-virus(HBU)-endemic areas. Methods: A total of 89 patients with small HCC (≤3cm in diameter) and adequate hepatic functional reserve(Child's A or B). who had undergone curative resection at Seoul National University Hospital between January 1985 and December 1994 were enrolled and retrospectively analyzed to evaluate clinical course and to assess the prognostic factors. Results: Serum HBsAg and anti-HCV were positive in 70% and 25% of patients, respectively, and pre-existing liver cirrhosis was found in 73% of patients. Postoperative mortality and morbidity occurred in 2.2% and 21% of patients, respectively. Cumulative recurrence rates at the end of 0.5, 1st, 2nd and 3rd year were 6.3Ya, 15.7%, 35.l% and 52.9%, respectively; cumulative probabilities of progression to hepatic decompensation at the end of 1st, 2nd and 3rd year were 4.2%, 19.4% and 22.6%, respectively; cumulative survival rates at the end of 0.5, 1st, 2nd and 3rd year were 91.1%, 89.9%, 77.9% and 74.5%, respectively. Six patients died as a result of tumor recurrence and eleven patients died of causes not related to tumor recurrence. The most important predictive factor of shorter survival time and higher rate of hepatic decompensation was vascular invasion. Age(≥50 years old), Child's classification and vascular invasion were factors affecting the rate of recurrence. Conclusion: These results verify that the clinical outcomes of patients with small HCC after curative resection in Korea are similar to those of patients with different etiology of HCC in other geographic areas. To improve the prognosis of patients with small HCC after curative resection, strict preoperative evaluation of the presence of vascular invasion and postoperative preservation of liver function are necessary as well as the close postoperative follow-up for the early detection of recurrence.
이효석,김정룡,이준성,우광훈,윤용범,송호준,석웅,윤정환 대한소화기학회 1999 대한소화기학회지 Vol.34 No.5
Since it was reported in 1944 that choledochal cyst could convert into cancer, there have been many studies and reports about the malignant conversion of choledochal cyst. The most common pathologic type of associated cancers is adenocarcinoma, and squamous cell carcinoma accounts for 4.8% of all associated cancers. Recently, we experienced an uncommon case of squamous cell carcinoma of the liver arising in a 16-year-old female, who had received choledochal cystectomy and choledochojejunostomy because of type Ⅳ choledochal cyst at 12 years of age. The abdominal computerized tomography scan showed a large (6 cm), ill-defined, low attenuated intrahepatic mass with peripheral bile duct dilatation. Ultrasonography-guided liver biopsy revealed squamous cell carcinoma with intercellular bridges. We report the first case of squamous cell carcinoma of the liver associated with choledochal cyst in Korea. At the time of diagnosis, it was centrally located and far advanced, invading portal vein. She died 3 months later.
비정맥류, 비궤양성 장관 내 출혈 및 용종 제거술 후 내시경적 밴드 결찰술
이정환,김유선,김은순,배원기,우광훈,문정섭,유권,전영빈,류정임,선휘경,하근우 대한소화기내시경학회 2001 Clinical Endoscopy Vol.23 No.2
Background/Aims: There is no consensus as to the best treatment for non-variceal, non-ulcer gastrointestinal hemorrhage. Endoscopic band ligation is an inexpensive, readily available, and easily learned technique in contrast to conventional thermal methods of endoscopic hemostasis. The purpose of this study is to define the effectiveness of endoscopic band ligation for non-variceal, non-ulcer gastrointestinal hemorrhage and post-polypectomy hemorrhage. Methods: Twenty eight patients were treated by band ligation between July 1996 and October 2000. The lesions treated were; Dieulafoy’s lesion in 13, Mallory-Weiss tear in 7, angiodysplasia in 1, post-polypectomy bleeding in 4, post-endoscopic mucosal resection bleeding in 2, post- endoscopic biopsy bleeding in I. Results: Endoscopic band ligation was successful in 25 of 28 cases. Additional sclerotherapy was necessary in two cases of Dieulafoy’s lesion. The remaining case was early band detachment. Conclusions: Endoscopic band ligation is effective for non-riceal, non-ulcer bleeding. It has the advantage of ease of use and is relatively inexpensive.