RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL

        우경미,김현만,고지승 생화학분자생물학회 2002 Experimental and molecular medicine Vol.34 No.5

        Pro-oxidant properties of ascorbate have been studied with uses of brain tissues and neuronal cels. Here we address potential mechanism of ascorbate coupling with glutamate to generate ox-idative stres, and the role which oxidized as-corbate (dehydroascorbate) transport plays in oxi-dative neuronal injury. Ascorbate in neurones can be depleted by adding glutamate in culture med-ium since endogenous ascorbate can be ex-bate/dehydroascorbate transport by depleting as-corbate in the neurons with the glutamate-heter-oexchange. However, ascorbate is known readily being oxidized to dehydroascorbate in the med-ium. Glutamate enhanced the dehydroascorbate uptake by cels via a glucose transporter (GLUT) from extracelular region, and cytosolic dehydro-ascorbate enhanced lipid peroxide production and reduced glutathione (GSH) concentrations. Iso-as-corbate, the epimer of ascorbate was ineffective in generating the oxidative stress. These obser-vations support the curent concept that the high rates of dehydroascorbate transport via a GLUT after the release of ascorbate by glutamate leads to peroxidation, the role of glutamate on ascor-bate/dehydroascorbate recycling being critical to induce neuronal death via an oxidative stress in the brain injury.

      • KCI등재

        Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones

        우경미,최영님,고승희,고지승,오귀옥,김각견 생화학분자생물학회 2002 Experimental and molecular medicine Vol.34 No.5

        Skeletogenesis occurs through either intramem-branous or endochondral ossification. In adition, some parts of the skeletal components maintain their cartilaginous characteristics throughout life without mineralization. Runx2 is known to be a cesses. In this study, we examined the expression patterns of two major isoforms of Runx2 in early skeletogenesis. During intramembranous bone for-mation, Runx2-type I (Runx2-I) was widely expres-sed in osteoprogenitor cels and active osteo-blasts, while Runx2-type II (Runx2-I) expression was stringently restricted to cels lining mineral-ized bones. Cels in permanent cartilage expressed colagen type II (Col-I) but never expresed Runx2 or Col-X. These permanent cartilages were wel Runx2-I was negative. In endochondral bone for-mation, Runx2 expression temporarily disappeared in Col-II-positive proliferating chondrocytes, but a secondary surge of Runx2-I expression occurred in the prehypertrophic zone before the minerali-zation of cartilage. Collectively, both Runx2 iso-forms showed very similar expression patterns in active bone forming areas; however, Runx2-I has an exclusive role in the early comitment stage of intramembranous or endochondral bone form-ing processes or in cels surrounding permanent cartilage.

      • KCI등재
      • KCI등재후보

        출산교실 참여 임산부들의 태아애착 영향요인

        우경미,지영주,김보라 사단법인 인문사회과학기술융합학회 2015 예술인문사회융합멀티미디어논문지 Vol.5 No.2

        본 연구는 임산부들의 태아애착에 영향을 미치는 요인을 파악하기 위해 실시되었다. 149명의 임산부가 참여하였으며, 2013년 1월5일에서 6월20일까지 자료수집 하였다. 자가보고형 설문지의 사용으로 자료수집 하였으며, 일반적 특성은 질문지를 이용하였고, 부모효능감, 부부친밀도, 태아애착은 측정도구를 이용하여 자료수집 하였다. SPSS 21 통계프로그램을 이용하여 기술통계, 상관분석, 회귀분석 하였다. 태아애착의 평균은 71.42이었고, 부부친밀도, 부모효능감, 개월은 태아애착에 22.7% 영향을 미치는 것으로 나타났다. 임산부를 대상으로 태아애착 중재 연구를 할 경우, 이러한 과정을 거쳐서 요인들이 고려된 중재의 적용이 필요하다고 본다. The purpose of this study was to influence factors of maternal fetal attachment among pregnant women in B city. Data were collected by structured questionnaires from July 5 to June 20 2013, and data were analyzed using descriptive statistics, correlation and multiple regression with SPSS/Win 21.0 program. The mean score for fetal attachment was 71.42. A multivariate approach showed that predictors explained 22.7% of variance in fetal attachment. Significant influence factors of fetal attachment were Couples intimacy(β=.17), parent efficacy(β=.37), and months(β=.16). The factors affecting highly effective intervention techniques need to be applied to the development of programs to upgrade fetal attachment among Pregnant women.

      • KCI등재

        대학생의 적절음주자기효능감에 영향을 미치는 요인

        우경미,지영주 사단법인 미래융합기술연구학회 2021 아시아태평양융합연구교류논문지 Vol.7 No.8

        The purpose of this study is to identify the factors influencing the self-efficacy for moderate drinking of undergraduate students. Data were collected through a survey of the undergraduate students from April 20 to June 4, 2019, self-questionnaires from Undergraduate Students. The research tool consists of employment stress, self-efficacy for moderate drinking, alcohol problem, academic stress, major aptitude, and other general characteristics. The collected data were analyzed using Descriptive statistics, Pearson's correlation coefficient, and multiple regression analysis. Based on the results, it was found that the more Employment stress (β =-.08, p=.001), Drinking problem (β =-.47, p<.001) and Academic stress (β =.15, p=.006) are the self-efficacy for moderate drinking level. Moreover, it was found that the self-efficacy for moderate drinking of undergraduate students’ test is necessary to detect early drinking problems in undergraduate students. In addition, it is necessary to operate an in-university intervention clinic on the drinking problem, which is a factor affecting the self-efficacy for moderate drinking. It was found that it was necessary to find solutions to academic stress and employment stress through student counseling.It was found that it was necessary to find solutions to academic stress and employment stress through student counseling. 본 연구의 목적은 대학생의 적절음주자기효능감에 영향을 미치는 요인을 규명하는 것이다. 데이터는 2019 년 4 월 20 일부터 6 월 4 일까지 학부생의 자기기입식 조사로 수집되었으며, 본 연구의 설문 조사 내용은 취업 스트레스, 자기효능감, 음주 문제, 학업 스트레스, 전공과 일반적인 특성으로 구성되었다. 수집 된 데이터는 기술 통계, 피어슨 상관 계수, 다중 회귀 분석을 통해 분석되었다. 본 연구에서는 취업 스트레스 (β =-. 08, p = .001), 음주 문제 (β =-. 47, p <.001), 학업 스트레스 (β = .15, p = .006)는 적절음주자기효능감에 영향을 미쳤다. 본 연구를 바탕으로 대학생의 조기 음주 문제 파악을 위해 대학생의 적절음주자기효능감 검사가 필요함을 알 수 있었다. 또한 적절음주자기효능감에 영향을 미치는 요인 인 음주 문제에 대한 대학 내 클리닉 운영이 필요하며, 학생 상담을 통한 학업 스트레스와 취업 스트레스에 대한 해결책을 탐색할 필요가 있음을 알게 되었다.

      • KCI등재

        The Effect of Unemployment in Depression by Age Group: Using 12 States' Data from the Behavioral Risk Factor Surveillance System

        우경미,Zhang, Zhisun 한국지역사회간호학회 2020 지역사회간호학회지 Vol.31 No.4

        Purpose: This study aims to explore the association between unemployment and depression in people from different age groups ranging from 18 to 65 years old. Methods: This study used a cross-sectional design. We performed bivariate analysis and multivariable logistic regression on the 2010 Behavioral Risk Factor Surveillance System (BRFSS) data from 12 states in the United States. Results: On a sample comprised of n=53,406 individuals, of whom 2,546 (7.8%) were identified as being depressed and 3,448 (10.6%) as unemployed, we found that individuals aged 61~65 years have a lower depression risk compared to those aged 18-25 after adjusting for other variables including employment status. However, people from 61~65 have higher increased risk of depression when unemployed compared to other age groups in all three models tested (3.95 times higher in unemployed people in model 1, and 2.81 times higher in model 2 and model 3). Conclusion: Our findings indicate that there may need to be more focus on older adults who are unemployed, with associated support services for their mental health. The results of our study indicate that although older adults are less likely to be unemployed, there are more likely to experience depression if they are unemployed (once other confounding factors are taken into account) than younger adults. Policies and interventions can be developed to address not only the physical difficulties but also the mental challenges with which older adults can be at risk facing in case of unemployment.

      • KCI등재

        보육교사의 역할갈등과 직무만족도에 미치는 영향요인

        우경미,지영주 사단법인 인문사회과학기술융합학회 2017 예술인문사회융합멀티미디어논문지 Vol.7 No.4

        The purpose of this study is to investigate the effects of safety accidents and safety education on their role conflict and job satisfaction. The data collection is 212 people who participated in the maintenance education in one of the metropolitan cities in June and September of 2012. The mean score of safety accidents, first aid ability, safety education, role conflict, and job satisfaction of the subjects were 26.93 ± 7.54, 16.81 ± 2.09, 32.19 ± 5.67, and 49.29 ± 11.82 and 102.89 ± 10.08, respectively. The factors affecting the role conflict in the safety accident, first aid ability, and safety education of the day care teachers were 31.9% in terms of administrative system, maintenance and promotion, safety accidents, and working conditions. The factors affecting the job satisfaction of the teachers' safety accidents, first aid ability, and safety education were 18.3% in terms of job title, conflict within the role, actual condition of safety education, and career experience. Therefore, in order to increase the role conflict and job satisfaction of the child care teachers, it is necessary to support the safety education and safety education along with the improvement of the administrative system, pay and promotion, and working conditions. 본 연구는 보육교사의 안전사고 및 안전교육 실태가 그들의 역할갈등과 직무만족에 미치는 여향을 알고자 하는데 목적이 있다. 자료 수집은 2012년도 6월과 9월 중 일개 광역시에서 시행된 보수교육에 참여한 자로 총 212명이다. 대상자들의 본 연구 대상자들의 안전사고발생, 응급처치능력, 안전교육실태, 역할갈등, 직무만족도의 평균점수는 각각 26.93±7.54, 16.81±2.09점, 32.19±5.67점49.29±11.82점, 102.89±10.08점이었다. 보육교사들의 안전사고발생, 응급처치능력, 안전교육실태가 역할갈등에 미치는 영향요인은 행정체계, 보수 및 승진, 안전사고발생, 근무여건 등으로 31.9%의 설명력을 보였다. 보육교사들의 안전사고, 응급처치능력, 안전교육실태가 직무만족도에 미치는 영향요인은 직위, 역할 내 갈등, 안전교육실태, 경력 등으로 18.3%의 설명력을 나타냈다. 따라서 보육교사의 역할갈등과 직무만족도를 높이기 위하여 행정체계, 보수와 승진, 근무여건의 향상과 함께 안전사고와 안전교육에 대한 뒷받침이 필요함을 알 수 있다.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼