목향(木香)과 차전초(車前草)가 위암세포(胃癌細胞)의 활성(活性), 증식(增殖), 자기살해능(自己殺害能) 및 세포주기관련 유전자 발현에 미치는 영향

오희라,고성규,Oh, Hee-Rah,Ko, Seong-Gyu 대한암한의학회 2001 大韓癌韓醫學會誌 Vol.7 No.1

Objective: This experimental study was carried out to evaluate the effects of Saussurea Radix and Plantaginis Herba on cellular viability, proliferation, apoptosis and expression of the cell cycle-related genes in cultured gastric cancer cells. Method :MTT assay for analysis of cellular toxicity and the effect on suppression of cellular viability, $[^{3}H]$ thymidine incorporation assay for evaluation of the effect on suppression of DNA replication, tryphan blue exclusion assay for measurement of induction of apoptosis and Quantitative RT-PCR for analysis of the effects on expression of cell cycle or apoptosis-related genes were performed. Results: Antitumor activity of Saussurea Radix associated with inhibition of cell cycle progression and promotion of apoptosis caused by transcriptional regulation of p53, p21/Wafl and the other related genes was observed.

Bicycle Repair Station

Heera Oh(오희라) 한국디자인학회 2015 한국디자인학회 국제초대전도록 Vol.2015 No.5

Apoptosis and Anti-proliferation by Saussurea lappa and Pharbits nil in AGS Human Gastric Cancer Cell Line

고성규,오희라,이선동,황귀서 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.1

急性期 腦卒中 患者의 機能回復度에 대한 臨床的 考察 : MBI, MAS를 이용하여

高性奎,吳熙羅 대한한방성인병학회 1997 韓方成人病學會誌 Vol.3 No.1

To evaluate objective validity of Oriental-medicine theraputic effect on the cerebrovascular accident, the functional improvements in Activities of Daily Living (ADL) and motor function were investigated using the score of Modified Barthel Index(MBI) and Motor Assessment Scale(MAS) in 34 acute stroke patients, which had been admitted to the Internal medicine department of Sang Ji Oriental Hospital from Novemver 1st 1996 to April 30th 1997. *상지대학교 한의과대학 부속병원 순환기내과학 교실 The results were as follows; 1. The changes in MBI and MAS scores at the time of admission, at 1 week and 2 weeks after have high correlations and statistically meaningful improvements and also by each Items. For 2 weeks after onset, there were functional improvements above 50% in both scales and more prominent improvements in the group of totally dependent. 2. On the changes in MBI and MAS scores by age, sex, cause of stroke, type of motor plegia and each Sasang constitution of inpatients in each groups, there were no statistically meaningful differences. 3. By site and size of lesion in the brain, there were statistically better high scores in the group of deep lesion than the mixed lesion, small lesion than large lesion on the changes in MAS scores after 2weeks, but there were no statistically meaningful differences on the changes in MBI scores. 4. As there was no statistically meaningful differences between changes in MBI and MAS scores by MBI scores at the time of admission, it has been found that functional state in the acute stage of stroke is not necessarily in proportion to prognosis in this study.

Hierarchical Task Analysis 를 적용한 장애인 접근성 평가 방법론

임승빈(Seungbin Yim),오희라(Heera Oh),노은영(Eunyoung Noh),김상민(Sangmin Kim),전정언(Jeongeon Jeon),이재형(Jaehyung Lee),이슬기(Sulki Lee),이성일(Seongil Lee) 한국HCI학회 2014 한국HCI학회 학술대회 Vol.2014 No.12

시연교육이 언어치료학과 학생들의 문제해결과정 및 실습자신감에 미치는 효과

김문정(Moon Jeoung Kim),오희라(Hee Ra Oh) 한국언어치료학회 2016 한국언어치료학회 학술발표대회 논문집 Vol.2016 No.12

Purpose: The purpose fo this paper was to assess if there is a relationship between Kolb learning style and learner variables including age, gender and simulation education among speech - language pathology students. This is a one group design with pretest and posttest for evaluation of effectiveness of an simulation education among sophomore speech-language pathology students according to their learning styles. Methods: Participants were 31 sophomore speech-language pathology students. The Kolb Learning Style Inventory (LSI) is used at many educational levels to determine the learning preferences of students and clinicians. The students’ learning styles were analyzed for associations with learner variables. They were categorized based on learning variables. Problem solving process, self-confidence were significantly enhanced by simulation education. Results: Learning style and educational effectiveness(problem solving process, self-confidence with practice) were measured. Learning styles of sopomore Speech-language pathology students were converger 15.6 %, assimilator 34.4%, accommodator 18.7%, and diverger 28.3%. Conclusion: Base on the results, devising stratagem to maximize and educational effectiveness will be needed through re-evaluation of relationship between learning style and effectiveness of simulation education.

확장된 Hierarchical Task Analysis 를 적용한 가전제품 접근성 평가 방법론

김상민(Sangmin Kim),오희라(Heera Oh),임승빈(Seungbin Yim),전정언(Jeongeon Jeon),홍진의(Jineui Hong),이재형(Jaehyung Lee),이태우(Taewoo Lee),이성일(Seongil Lee) 한국HCI학회 2016 한국HCI학회 학술대회 Vol.2016 No.1

현재 국내뿐 아니라 전세계적으로 장애인 인구가 증가하고 있다. 그러나 가전제품 사용에 있어 일반인 사용자와 장애인 사용자의 격차는 줄지 않고 지속적으로 증가하고 있는 추세이다. 하지만 가전제품들의 접근성 평가와 분석에 대한 연구는 미비한 편이며, 기존의 가이드라인, 체크리스트 중심의 접근성 평가 연구는 주관적이고 정성적인 한계를 극복하지 못하고 있다. 과업분석(Task Analysis)방법 중 하나인 HTA(Hierarchical Task Analysis)기법을 적용한 선행연구 역시 몇 가지 보완점을 가지고 있다. 본 연구에서는 기존의 HTA 를 활용한 가전제품의 접근성 평가 방법론을 확장하여 선행연구의 문제점을 극복한 새로운 평가방법론을 제안한다. 확장된 HTA평가방법론은 다양한 사용자 유형의 과업 패턴을 반영하도록 구성된다. 또한 HTA 의 각 Task behavior 에 대응하는 제품의 접근성 요소를 평가지표로 활용한다. 결과적으로 확장된 HTA 를 통해 독립적이었던 장애인의 가전제품 사용패턴을 포괄하고, 산술적으로 산출된 접근성 평가결과를 통해 종합적인 해석을 제시한다. 이를 위해 본 연구에서는 선행연구사례와 대비하여, 다양한 사용유형을 포괄하는 확장방향을 제시한다. 또한 확장형 HTA 를 통해 새롭게 얻어지는 접근성 평가 결과를 제시하여 선행연구의 문제점을 보완한다. Nowadays, In both overseas and domestic areas, With an increasing number of handicapped people, gaps arises between handicapped users and normal users. However, Estimation and Analysis of accessibility of home appliances are in insignificant steps, and existing guideline and research with standard that is consisted of checklist are just subjective and qualitative. The precedent research that applied "HTA(Hierarchical Task Analysis)" solution which is known as one of ways of "Task Analysis" also has a few points that have to change. In this paper, by expanding a methodology of handicapped accessibility evaluation that is based on p recedent " HTA" , We offer a more analytical evaluating methodology. That expanded "HTA" is compromised to show a physical pattern of various users. Expanded "HTA" uses a offered Task behavior and product"s interface that follows with Task behavior. With expanded HTA, We can detect the accessibility condition of product and can get a quantifiable result. And that can derive a accessibility evaluation and evaluating barometer. In the future, we look forward to Using offered methodology in this research conducts accessibility evaluation that considers a various user members and quantifiable derives interface"s components that needs to be solved and changed.

차량 내부 인터페이스 기반 운전자의 Eye-Hand Coordination 과 운전 부하간의 관계 모델

임승빈(Seungbin Yim),김상민(Sangmin Kim),오희라(Heera Oh),전정언(Jeongeon Jeon),이재형(Jaehyung Lee),이성일(Seongil Lee) 한국HCI학회 2016 한국HCI학회 학술대회 Vol.2016 No.1

본 연구는 운전자가 차량 HMI (Human Machine Interface)를 사용할 때, 디스플레이와 조작부의 위치에 따라 변화하는 운전자의 사용행태를 분석하는 것이 목적이다. Eye-Hand Coordination 을 이루는 요소를 찾고 최적의 Eye-Hand Coordination 을 갖는 디스플레이와 조작부의 위치 및 설계에 반영할 수 있는 실질적인 모델을 제시하고자 한다. 운전자의 사용 행태중 운전자의 눈과 손의 움직임에 따른 Eye-Hand Coordination 의 구성 요소를 디스플레이와 조작부의 거리로(1), 스티어링 휠과 조작부의 거리로(2), Fixation Point 와 디스플레이의 거리로(3), Fixation Point, Control Start Point, 디스플레이, 조작부 네개의 점으로 이루어진 영역으로(4) 총 4 가지의 변수를 도출하였다. 연구결과 차량 내의 인지부하에 대한 다양한 가설을 정립하였으며 Eye-Hand Coordination 구성요소와 운전자의 부하 및 수행 시간과의 관계를 단순회귀분석과 다중회귀분석을 통해 분석하였다. 이를 통해 운전자의 부하 및 수행시간을 예측할 수 있는 8 가지의 Eye-Hand Coordination Model 을 정립하였다. 도출된 회귀모형 중에는 신체적 부하를 예측하는 회귀식이 64.2%로 큰 설명력을 지닌 회귀모형도 도출되었다. 본 연구를 통해 현재 차량의 내부 인터페이스의 실측 데이터를 통해 운전 부하를 비교 평가할 수 있으며, 향후 차량 내부 인터페이스를 설계할 때, 디스플레이와 조작부의 레이아웃을 함께 고려할 수 있는 근거 연구 및 기반 자료가 될 것이다. The purpose of this paper, it suggested the best combination of display and control and deduced eye-hand coordination model focusing on location of display and controls. First components of eye-hand coordination defined as following 4 factors; (1) distance between display and control, (2) distance between steering wheel and control, (3) distance between fixation point and display, (4) perceived plain of eye-hand coordination consisting of fixation point, control start point display and control. There is a positive correlation between eyehand coordination components and driving workload/performance time. Through this, 8 regression equations which can predict driving workload/performance time were deduced. The biggest explanation power equations(64.2%) was physical demand model. The equations of predicting effort, performance inhibition and time showed a similar tendency. The regression model can be used comparison evaluation of invehicle interior by distance measurement without experiment. Therefore, even if they are not expert, everyone can measure and compare driving workload easily and simply. This study can be used as a basic research on in-vehicle design considered eye-hand coordination by location of display and control.