Risks of colorectal cancer and biliary cancer according to accompanied primary sclerosing cholangitis in Korean patients with ulcerative colitis: a nationwide population-based study

오은혜,Kim Ye-Jee,Minju Kim,박승하,김태오,박상형 대한장연구학회 2023 Intestinal Research Vol.21 No.2

Background/Aims: We conducted a nationwide population-based study to investigate incidence rates of colorectal and biliary cancers according to accompanying primary sclerosing cholangitis in Korean ulcerative colitis patients. Methods: We used the Health Insurance Review and Assessment claim database from January 2007 to April 2020. Standardized incidence ratios of colorectal and biliary cancers in ulcerative colitis patients were calculated. Results: Among 35,189 newly diagnosed ulcerative colitis patients, 1,224 patients were diagnosed with primary sclerosing cholangitis. During the study period, 122 and 52 patients were diagnosed with colorectal and biliary cancers, respectively. Incidences of colorectal cancer were not higher in ulcerative colitis patients than those in the general population (standardized incidence ratios, 0.83; 95% confidence interval, 0.69–0.99), regardless of accompanied primary sclerosing cholangitis (standardized incidence ratio, 0.73; 95% confidence interval, 0.24–1.71). While incidences of biliary cancer were not higher in ulcerative colitis patients than those in the general population (standardized incidence ratio, 1.14; 95% confidence interval, 0.80–1.58), these were much higher with accompanied primary sclerosing cholangitis (standardized incidence ratio, 10.07; 95% confidence interval, 5.75–16.36). Cumulative incidences of colorectal and biliary cancers increased in patients who were diagnosed with ulcerative colitis at an older age. Conclusions: In Korean ulcerative colitis patients, colorectal cancer incidences were not higher than those in the general population regardless of accompanied primary sclerosing cholangitis. However, biliary cancer incidences were much higher in ulcerative colitis patients with primary sclerosing cholangitis than in those without, or in the general population.

은퇴 노인소비자의 소비 행위를 통한 정체성 찾기

오은혜,최혜경 한국소비자학회 2014 한국소비자학회 학술대회 Vol.2014 No.5

The effect of L2 experience on the perception of L1 prosody

오은혜 한국음운론학회 2017 음성·음운·형태론 연구 Vol.23 No.2

The effects of second language experience on adult learners’ perception of native language prosody are investigated. Three sets of 13 sentences produced in Korean, Mandarin, and Japanese, respectively, by three female speakers were low-pass filtered and presented to three groups of 10 participants with different language backgrounds: Native Korean speakers with no L2 experience (NK), native Mandarin Chinese speakers (NC) and Korean learners of Chinese (KC) with an average LOR in China of 1 year. The participants were instructed to listen to each stimulus and decide whether it was Korean or not based on the suprasegmental features. Overall, the NK group (76%) revealed significantly higher accuracy than the KC (65%) or the NM group (57%). However, the NM participants with extensive Korean experience showed a significantly high accuracy for both Korean (75%) and Chinese (84%). The results indicate a significant effect of L2 experience on the acquisition of L1 prosody, yet the KC group’s lower accuracy for Korean, on the other hand, suggests that too much attention may have been directed towards acoustically salient L2 cues (e.g., F0 range) in the perception of L1 prosody.

Incidence and Clinical Significance of Positional Downbeat Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo

오은혜,이재훈,김효정,최서영,최광동,최재환 대한신경과학회 2019 Journal of Clinical Neurology Vol.15 No.2

Background and Purpose The aim of this study was to determine the incidence and clinical significance of positional downbeat nystagmus (pDBN) after treatment of posterior canal (PC) benign paroxysmal positional vertigo (BPPV). Methods We recruited 77 patients with a diagnosis of PC BPPV, and assessed the presence of pDBN during follow-up positional tests after performing the Epley maneuver. Results An immediate response to the Epley maneuver was exhibited by 57 of the 77 patients, with resolution of their positional torsional upbeat nystagmus (pT-UBN). Twenty-two (39%) of them exhibited pDBN during follow-up tests performed 1 hour later. The latency and duration of pDBN were 3.2±2.0 and 12.0±10.0 s (mean±SD), respectively. The maximum slowphase velocity of pDBN was 5.1±2.5 degrees, and ranged from 2.0 to 12.2 degrees. A torsional component was also observed in six patients. The patients with pDBN were much more likely to develop a typical form of PC BPPV again at a 1-week follow-up (5/22, 23%) compared to those without pDBN (1/31, 3%; p=0.036). pDBN disappeared in all patients within 6 months. Conclusions Our study found transient pDBN in 40% of patients with PC BPPV after the immediate resolution of positional vertigo and pT-UBN. pDBN may be attributed to residual debris in the distal portion of the PC, which can move toward the ampulla producing an ampullopetal flow of endolymph during positioning.

Effects of age of L2 acquisition and L2 experience on the production of English vowels by Korean speakers

오은혜,신은영 한국음성학회 2023 말소리와 음성과학 Vol.15 No.3

The current study investigated the influence of age of L2 acquisition (AOA) and length of residence (LOR) in the L2 setting country on the production of voicing-conditioned vowel duration and spectral qualities in English by Korean learners. The primary aim was to explore the ways in which the language-specific phonetic features are acquired by the age of onset and L2 experience. Analyses of the archived corpus data produced by 45 native speakers of Korean showed that, regardless of AOA or LOR, absolute vowel duration was used as a salient correlate of voicing contrast in English for Korean learners. The accuracy of relative vowel duration was influenced more by onset age than by L2 experience, suggesting that being exposed to English at an early age may benefit the acquisition of temporal dimension. On the other hand, the spectral characteristics of English vowels were more consistently influenced by L2 experience, indicating that immersive experience in the L2 speaking environment are likely to improve the accurate production of vowel quality. The distinct influence of the onset age and L2 experience on the specific phonetic cues in L2 vowel production provides insight into the intricate relationship between the two factors on the manifestation of L2 phonological knowledge.

지역거점병원 외래진료부에서의 감염 취약 공간 분석에 관한 연구

오은혜,권지훈 대한건축학회지회연합회 2017 대한건축학회연합논문집 Vol.19 No.3

본 연구는 지역거점병원 내 외래진료부의 이용자 이동 과정에서 발생하는 원내 감염을 예방하기 위해 감염 위험이 높은 국지적 공간을 추출하는 방안과 그 적용 결과를 제시할 목적으로 수행되었다. 연구 방법은 다음과 같다. 첫째, 외래진료부, 병원 내 감염, 공간구문론, 행위자 기반 분석에 대한 선행연구를 고찰하였다. 공간구문론 기반으로 외래진료부 공간 구조를 분석하였다. 지역거점병원의 외래진료부 평면을 이용하여 행위자 자연 이동 시뮬레이션 분석과 대상 병원의 현장 조사를 통해 보행량을 측정하였다. 외래진료부의 공간 구성은 공용 공간, 응급실, 진단, 검사, 치료, 지원 서비스 공간을 포함한다. 폐렴 환자를 치료하는 의료시설 내 시뮬레이션 결과로 공용 공간의 대기 공간, 주출입구, 인접한 복도가 높게 산출되었다. 실제 통행량 분석 결과로 주출입구와 의료시설 내 주요 복도에서 높게 나타났다. 과밀한 공간은 하나의 병원에서만 시뮬레이션과 현장 조사에서 모두 확인되었다. 다른 병원은 시뮬레이션 결과와 조사 결과에 차이를 보였다. 또한 이 연구는 병원에서 이용자의 이동 경로를 고려하는 시뮬레이션의 필요성을 향후의 연구 과제로 제안한다. This study aimed to develop a method finding local spaces vulnerable to infection risk and proposed the result of analysis with using the method for preventing hospital infection happened during user’s movement process at outpatient clinic area in regional health care center. The study method is as follows; Firstly, research literatures regarding outpatient area, hospital infection and space syntax and agent-based analysis were reviewed. Secondly, space structures were analyzed at outpatient areas on the basis of space syntax theory. Thirdly, natural movement simulations using agent-based models and site surveys counting users’ visits to several spaces in hospitals were conducted. Outpatient clinic area includes public space, emergency room, diagnosis, checkup, remedial treatment and support service. The simulation results showed that agents’ movements in medical facilities treating pneumonia patients were highly frequent at waiting spaces, main entrances and nearby corridors. The survey results revealed that users’ movements appeared crowded at main entrances and inside corridors. Highly crowded spaces were clarified at only one hospital with both simulation and survey. The other hospital showed difference between the simulation result and the survey result. This study would also suggest the need of simulation considering user’s movement route in hospital as future study topic.

The acquisition of timing patterns in children’s productions

오은혜 한국음운론학회 2015 음성·음운·형태론 연구 Vol.20 No.2

The current study examined differences in the segmental duration of adults’ and school-aged children’s speech. The purpose of the study was to understand the durational patterns and rhythmic characteristics of school-aged children’s speech production. The effects of vowel identity, final coda voicing and number of syllables on absolute and relative duration were explored. Similar to previous studies, segmental duration in absolute terms was found to be significantly longer for children than for adults. However, no significant differences were found between adults and children in terms of the relative timing patterns of inherent vowels, vowels before voiced and voiceless consonants or stressed vowels in multisyllabic words. An adult-like timing control found in children’s production is interpreted to indicate a high level of phonological knowledge about the relative timing of sequential segments, despite some evidence of oral-motor constraints.

지역거점 병원의 소아청소년 감염 예방과 통제를 위한 공간 분석 연구

오은혜,권지훈 한국청소년시설환경학회 2017 청소년시설환경 Vol.15 No.1

원격대학 이주민 재학생의 학업적응 과정 분석

은혜경(殷惠瓊) 서울대학교 교육연구소 2018 아시아교육연구 Vol.19 No.3

본 연구의 목적은 국내 원격대학에 입학한 이주민 학생들의 학업적응 과정을 분석하는 것이다. 이를 위해 K원격대학에 입학한 후 글로벌장학금을 받은 우수 이주민 학생 9명을 대상으로 개별 면접을 실시하였으며, 근거이론 접근(grounded theory approach)에 따라 면접 결과를 분석하였다. 먼저 개방코딩(open coding)을 실시하여 총 28개의 범주를 도출하였으며, 범주들(categories) 간의 관계를 설정하는 축코딩(axial coding)을 진행하여 원격대학에 입학한 이주민 재학생의 학업적응 패러다임 모형을 도출하였다. 즉, 원격대학에 입학한 이주민 학생들이 학업적응 과정에서 경험하는 중심현상(phenomenon)은 ‘원격대학생활의 어려움에 압도됨’으로 나타났으며, 중심현상의 직접적 원인이 되는 인과적 조건(casual conditions)은 ‘대학교육을 받기에는 한국어 실력이 부족함’, ‘한국사람과의 관계에 대한 두려움’인 것으로 분석되었다. 중심현상에 대한 작용/상호작용 전략(action/interaction strategies)은 ‘포기할까 고민함’, ‘각오를 다짐’, ‘현실과 타협함’, ‘주변사람들에게 도움을 요청함’, ‘교내 학습지원 제도를 활용함’, ‘오프라인 활동에 참여함’, ‘정보를 탐색함’, ‘시험위주로 공부함’, ‘공부에 몰입함’인 것으로 나타났다. 이들의 학업적응 결과(consequences)는 ‘혼자가 아님을 알게 됨’, ‘학습의 즐거움을 경험함’, ‘원격대학 학습법을 터득하고 전수함’, ‘한국사회 적응력이 향상됨’, ‘이주민 정체성을 긍정적으로 재구성함’ 등이었으며, 학업적응 과정은 혼란, 탐색, 적응초기, 몰입 단계를 통해 이루어지는 것으로 나타났다. 마지막으로 본 연구가 원격대학 이주민 학생의 학업적응 관련 이론과 실제에 주는 시사점, 본 연구의 제한점과 후속 연구를 위한 제언 등이 제시되었다. The purpose of this study is to analyse the process of academic adjustment of immigrant students who enter distance university. In order to carry on this study, 9 immigrant students who were granted scholarship after entrance to the K distance university were interviewed and the result of the interview was analyzed based on the grounded theory approach. Firstly, open coding was conducted and 28 upper levels were categorized then the academic adjustment paradigm modeling of those immigrant student was constructed by processing axial coding, which establishes the relationship among upper categories. It means central phenomenon of the immigrant students during they were on the process of academic adjustment is interpreted as ‘overwhelming due to academic difficulties in distance university’ and casual condition directly affects to the central phenomenon is ‘due to lack of Korean language skills to learn university level education’ and ‘fears of having relationship with native Koreans’ Actional/interactional strategies towards the central phenomenon are categorized as ‘considering leave halfway through’, ‘resolute’, ‘compromise with the reality’, ‘ask help to others’, ‘utilize supporting programme in university’, ‘participate in off-line activity’, ‘search information’, ‘study for only exams’, and ‘concentrate on studying’. The responded as a result of the academic adjustment saying ‘realize I am not alone’, ‘experience the pleasure of studying’, ‘know how to do distance learning and let others know’, ‘positively re-establish immigrants’ identity’ and the overall process of immigrant students was characterized by ‘confusion-exploring-initial stage of adjustment-concentration stage’ levels. Lastly, implication, limitation and proposal for further studies are addressed.

임상 추론: 두통과 복시로 내원한 38세 남자

오은혜,최재환 대한신경과학회 2018 대한신경과학회지 Vol.36 No.4

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