부산 신항 개발 기본계획

오세범,김영수 한국해안해양공학회 1997 학술강연회 발표논문초록집 Vol.1 No.1

Purpose of the Pusan Newport development is to elevate national competition force through handling the increasing traffic volume of the 21th century and to make her 「Hub Porti」of Northeast Asia Container logistics market

소각중성자산란법을 이용한 API-X65 강의 수소유기균열의 발생점 연구

오세범,한상선,최용,고성웅,정환교,이창선,신은주,성백석,한영수 한국표면공학회 2014 한국표면공학회 학술발표회 초록집 Vol.2014 No.5

초음파 탐상 검사를 이용한 유동가속부식에 의한 배관 감육 분석

오세범,이종연,김동진,김경모,김종범 한국비파괴검사학회 2022 한국비파괴검사학회지 Vol.42 No.3

Flow acceleration in a pipe promotes iron ion transport. It may cause flow accelerated corrosion (FAC) of carbon steel and secondary pipe damage in a nuclear power plant, leading to a major accident. The flow acceleration corrosion phenomenon was verified through an empirical facility to establish an ultrasound-based thickness measurement system that can monitor this phenomenon in a stable and real time. The fluid flow inside the pipe was corroded in pure water at 150℃ with dissolved oxygen of 1 ppb or less in a flow rate range of 7-12 m/s in 6,950 hours. After the test, the surface of the corroded sample was closely observed to verify the difference between the speed of corrosion and the oxide shape of the surface depending on the Cr content of steel, and it was verified that two different pipe of steel have different surfaces in the welding part. The cross-section of the corroded sample was confirmed by checking whether an oxide was generated using an optical microscope (OM) and scanning electron microscope (SEM). The tendency of reducing the thickness of the two materials according to the Cr content was compared through CT (computed tomography). The thickness of the pipes of the two materials was evaluated according to the internal fluid conditions through ultrasonic inspection at room temperature when the empirical facility was not operating.

정상인에서 시간 도메인과 스펙트럼 도메인 빛간섭단층촬영으로 측정한 황반두께 측정의 반복성 및 일치도

오세범,조원빈,문준웅,김형찬 대한안과학회 2009 대한안과학회지 Vol.50 No.5

Purpose: To compare the repeatability and agreement of macular thickness measurements using time domain (TD) optical coherence tomography (OCT) and spectral domain (SD) OCT in normal subjects. Methods: Thirty-four normal subjects were included. Three consecutive macular measurements were taken with TD OCT and SD OCT. Total and regional macular thickness and total macular volume obtained by the two OCTs were compared. Withinsubject standard deviation (Sw), coefficient of variation (CVw), and the intraclass correlation coefficient (ICC) were calculated to evaluate repeatability. The agreement was examined with Bland Altman plots. The correlation was also evaluated with Pearson correlation coefficients and multiple regression analysis. Results: Sw for foveal thickness, total macular thickness, and total macular volume were 11.53 μm, 7.58 μm, and 0.48 mm³ for TD OCT and 6.69 μm, 2.55 μm, and 0.09 mm³ for SD OCT, respectively. The values for SD OCT were consistently lower, and this result was statistically significant. The range of the respective CVw and ICC values were 1.10~2.78% and 0.78~0.96% for TD OCT, and 0.29~0.94% and 0.92~0.99% for SD OCT, respectively. The SD OCT showed better repeatability for macular thickness measurements(all with p≤0.001). The spans of 95% limits of agreement for foveal thickness, total macular thickness, and total macular volume were 67.94 μm, 29.01 μm, and 0.98 mm3, respectively. The Pearson correlation coefficient of foveal thickness, total macular thickness, and total macular volume between the two OCT’s was statistically significant. Conclusions: Although both OCTs are reliable for macular thickness measurements, SD OCT shows better repeatability compared with TD OCT. Although macular thickness measurements obtained from the two OCTs can not be used interchangeably due to low agreement by different standards of measurement, there was a statistically significant correlation between the two OCT’s. 목적: 정상인에서 time domain (TD) OCT와 spectral domain (SD) OCT로 황반두께를 측정해 그 반복성과 일치도를 비교해 보고자 하였다. 대상과 방법: 정상인 34안을 대상으로 TD OCT와 SD OCT로 3회 연속 황반두께와 총황반부피를 측정해 비교하였다. 개체 내 표준편차, 변동계수, 급내상관계수로 반복성을 알아보았고, Bland Altman plot으로 두 OCT의 일치도를 평가하였다. 또한 Pearson 상관계수 및 다중회기분석을 통해 두 OCT 사이의 상관관계에 대해서도 알아보았다. 결과: TD OCT와 SD OCT로 측정한 중심와두께, 총황반두께, 총황반부피의 개체 내 표준편차는 각각 11.53 μm/6.69 μm, 7.58 μm/2.55 μm, 0.48 mm³/0.09 mm³로 SD OCT에서 유의하게 낮았다. 변동계수와 급내상관계수는 TD OCT에서 각각 1.10~2.78%, 0.78~0.96%이었고, SD OCT에서 각각 0.29~0.94%, 0.92~0.99%이었다. 중심와두께, 총황반두께, 총황반부피의 95% 일치도 범위는 각각 67.94 μm, 29.01 μm, 0.98 mm3이었다. 두 OCT 사이의 모든 황반두께와 총황반부피는 통계적으로 유의한 상관관계를 보였다. 결론: 두 OCT 모두 황반두께 측정에서 높은 신뢰성을 보이나, SD OCT에서 더 높은 반복성을 보였다. 두 OCT로 측정한 황반두께는 측정기준의 차이 때문에 낮은 일치도를 보여 상호 교환적이지 못하나 유의한 상관관계를 보였다.

나이관련 황반변성의 맥락막신생혈관에서 베바시주맙 유리체강내 주입술 효과와 예후인자

오세범,조원빈,문준웅,김형찬,Se Beum Oh,Won Bin Cho,Jun Woong Moon,Hyung Chan Kim 대한안과학회 2009 대한안과학회지 Vol.50 No.2

Purpose: To investigate the effects and prognostic factors related to intravitreal injection of bevacizumab on patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. Methods: The medical records of patients who received 3 consecutive intravitreal injections of bevacizumab (1.25 mg/0.05 ml, 6 weeks interval) for subfoveal choroidal neovascularization secondary to age-related macular degeneration and followed up for more than 12 months were reviewed (a total of 31 eyes; male, 20; mean age, 72.3±7.5 years). Baseline best corrected visual acuity, foveal thickness, and total macular volume were compared with those after 1, 4, and 12 months. The therapeutic effects were investigated with regard to factors such as age, sex, initial visual acuity, lesion size, subtypes of choroidal neovascularization, pigment epithelial detachment, submacular hemorrhage, and previous history of photodynamic therapy. Results: Initial visual acuity (logMAR), foveal thickness, and total macular volume were 0.74±0.49, 320±88 μm and 9.50±2.99 mm3, respectively. Visual acuity improved to 0.68±0.61 (p=0.012), and foveal thickness and total macular volume decreased to 218±69 μm and 6.32±0.71 mm3 (p<0.001), respectively, at 12 months. Visual improvement was achieved less often in patients who were 75 years or older and who had lesions 3 disc areas or greater and relatively good initial vision at 12 months. Conclusions: Intravitreal bevacizumab injection has beneficial effects for patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration with regard to function and anatomy. However, it should be noted that visual improvement may be limited in older patients with larger lesions and good initial vision.

회원작품 - 유취헌

오세범,Oh, Sebeom 대한건축사협회 2021 建築士 Vol.626 No.-

당뇨황반부종에서 시간과 스펙트럼 도메인 빛간섭단층촬영으로 측정한 황반두께의 반복성과 일치도

오세범,문준웅,김형찬,Se Beum Oh,MD,Jun Woong Moon,MD,Hyung Chan Kim,MD,PhD 대한안과학회 2010 대한안과학회지 Vol.51 No.3

Purpose: To evaluate the repeatability of macular thickness measurements using time domain (TD) OCT and spectral domain (SD) OCT in diabetic macular edema. Methods: In 42 eyes of 42 patients with diabetic macular edema, three consecutive macular measurements were performed with TD OCT and SD OCT, and measurements for macular thickness and total macular volume obtained by the two OCTs were compared. The within-subject standard deviation (Sw), coefficient of variation (CVw), and intraclass correlation coefficient (ICC) were calculated to assess repeatability, with agreement between measurements assessed with Bland Altman plots. The correlations were also evaluated via the Pearson’s correlation coefficient. Results: The Sw of TD OCT and SD OCT for foveal thickness, total macular volume were 29.67 μm/16.44 μm, 1.26 mm3/0.23 mm3, respectively, and were significantly lower in SD OCT. The ranges of the respective CVw and ICC values were 1.10-2.78%, 0.78~0.96 for TD OCT, and 0.29~0.94%, 0.92~0.99 for SD OCT. The SD OCT showed better repeatability for macular thickness measurements (all p≤0.001). The 95% limits of agreement for foveal and total macular volume were 88.9 μm, 2.4 mm3, respectively. The Pearson’s correlation coefficients of macular thickness and total macular volume between the two OCT methods were statistically significant (p=0.88-0.99). Conclusions: Although both OCTs proved reliable for macular thickness measurements in diabetic macular edema, SD OCT shows better repeatability than TD OCT. Although macular thickness measurements obtained from the two OCTs cannot be used interchangeably, there were statistically significant correlations between measurements obtained using the two OCTs. J Korean Ophthalmol Soc 2010;51(3):372-378

Analysis of Pipe Thickness Reduction according to pH in FAC facility with In situ Ultrasonic Measurement Real Time Monitoring

오세범,김종범,이종연,김동진,김경모 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.1

Flow accelerated corrosion (FAC) is a type of pipe corrosion in which the pipe thickness decreases depending on the fluid flow conditions. In nuclear power plants, FAC mainly occurs in the carbon steel pipes of a secondary system. However, because the temperature of a secondary system pipe is over 150 °C, in situ monitoring using a conventional ultrasonic non-destructive testing method is difficult. In our previous study, we developed a waveguide ultrasonic thickness measurement system. In this study, we applied a waveguide ultrasonic thickness measurement system to monitor the thinning of the pipe according to the change in pH. The Korea Atomic Energy Research Institute installed FAC-proof facilities, enabling the monitoring of internal fluid flow conditions, which were fixed for ~1000 h to analyze the effect of the pH. The measurement system operated without failure for ~3000 h and the pipe thickness was found to be reduced by ~10% at pH 9 compared to that at pH 7. The thickness of the pipe was measured using a microscope after the experiment, and the reliability of the system was confirmed with less than 1% error. This technology is expected to also be applicable to the thickness-reduction monitoring of other high-temperature materials.

당뇨황반부종의 치료에서 유리체강내 트리암시놀론과 베바시주맙 주입술의 효과 비교

오세범,문준웅,김형찬 대한안과학회 2009 대한안과학회지 Vol.50 No.8

Purpose: To compare the effect of an intravitreal injection of triamcinolone acetonide with bevacizumab in the treatment of diabetic macular edema (DME). Methods: For this study, the medical records of patients with diabetic macular edema, who received intravitreal triamcinolone injection (IVTA) or intravitreal bevacizumab injection (IVB), were reviewed. Best corrected visual acuity (BCVA), central macular thickness (CMT) and total macular volume (TMV) were evaluated before injection and at 1 week, 1 month, 2 months, 3 months, and 6 months after injection. The adverse events, such as increased intraocular pressure, and progression of cataract, were also reviewed. Results: A total of 72 eyes from 72 patients, (IVTA: 40 eyes, IVB: 32 eyes) were included in this study. In the IVTA group, BCVA improved significantly at 1 week after injection and was maintained until 3 months after injection. In the IVB group, BCVA improved significantly at 1 week after injection and was maintained until 2 months after injection. In the IVTA group, CMT and TMV decreased significantly at 1 week after injection and were maintained until 3 months after injection, while in the IVB group CMT and TMV were maintained until 2 months after injection. The IVTA group showed significantly better results in visual improvement, CMT and TMV reduction compared to the results of the IVB group, from 1 month to 3 months after injection. In the IVTA group, intraocular pressure increased to more than 25 mmHg in 12.5% of patients during the follow-up period. Conclusions: While the functional and anatomical improvements are achieved by both IVTA and IVB for diabetic macular edema, the effect of IVTA is more prominent with longer duration than IVB. 목적: 당뇨황반부종 치료에서 유리체강내 트리암시놀론 주입술과 베바시주맙 주입술의 효과에 대해 알아보고자 하였다. 대상과 방법: 당뇨황반부종의 치료로 유리체강내 트리암시놀론 주입술(Intravitreal Triamcinolone Acetonide, IVTA) 또는 베바시주맙 주입술(Intravitreal Bevacizumab, IVB)을 시행 받은 환자들에 대하여 후향적 의무기록조사를 통하여 시술 전, 시술 후 1주, 1개월, 2개월, 3개월, 6개월에 최대교정시력, 중심황반두께, 총황반부피를 조사하였다. 또한, 안압상승, 백내장 진행 등의 부작용에 대해서도 조사하였다. 결과: 대상안은 총 72명 72안(IVTA군: 40안, IVB군: 32안)이었다. 최대교정시력은 IVTA군에서는 시술 후 1주일부터 3개월까지 유의한 시력호전을 보였고, IVB군에서는 시술 후 1주일부터 2개월까지 유의한 시력호전을 보였다. 중심황반두께와 총황반부피는 IVTA군에서 시술 후 1주일부터 3개월까지 유의하게 감소하였으며, IVB군에서는 시술 후 1주일부터 2개월까지 유의하게 감소하였다. IVTA군에서 IVB군에 비해 1개월부터 3개월까지 유의한 시력호전과 중심황반두께 및 총황반부피의 감소를 보였다. IVTA군에서 경과관찰 중 5안 (12.5%)에서 안압이 25 mmHg 이상으로 상승하였다. 결론: 당뇨황반부종에서 유리체강내 트리암시놀론과 베바시주맙 주입술 모두 단기간 기능적, 해부학적 호전을 보인다. 하지만 트리암 시놀론 치료군에서 더 좋은 치료효과를 보였고, 그 지속기간도 더 길었다.

愚公移山

오세범 고시계사 2011 考試界 Vol.57 No.1