유경 횡복직근근피판(Pedicled TRAM Flap)을 이용한 유방재건술

오세광,홍성표,고석환,이두형 대한미용성형외과학회 1998 Archives of Aesthetic Plastic Surgery Vol.4 No.1

성인 환자에서 초음파로 측정한 시각신경집 지름이 두개강 내 압력 상승을 발견하 는데 유용한가?

오세광,조용철,구도현,유승,이진웅,김승환,유인술,유연호 대한응급의학회 2008 大韓應急醫學會誌 Vol.19 No.6

Purpose: To evaluate the utility of ONSD (optic nerve sheath diameter) measured by US (ultrasonography) in detecting the presence of increased intracranial pressure. Methods: This prospective study was done from October, 2007, to March, 2008. Patients who were 18 years or younger, had a recent ocular or periocular disease, had an abnormal Q test (Queckenstedtis test), or were uncooperative were excluded. The patients were divided into group A (increased CSF pressure group ≥200 mmCSF) and group B (normal CSF pressure <200 mmCSF). The ONSDs were measured using a 3~12 MHz ultrasonographic probe on the closed eyelids. We analyzed the correlation between the CSF (cerebrospinal fluid) pressure and the ONSD. Results: There were 21 patients in group A and 70 patients in group B. The mean for binocular ONSDs in group A was 5.1±0.6 mm and 4.5±0.4 mm in group B (p<0.01). The CSF pressure correlated with the ONSD (Correlation Coefficient=0.54) (p<0.01). In the ROC curve (Receiver operating characteristic curve) for ONSD to distinguish group A from B, the AUC was 0.8 (95% confidence interval 0.7~0.9) with a sensitivity of 81.0%, and a specificity of 75.7% when the cut off value was set at 4.7 mm. Conclusion: The ONSD was related to the CSF pressure, with a difference in the ONSD between group A and group B. The ONSD, as measured by US, can be used to detect the presence of high ICP.

고칼륨혈증을 동반한 심정지 환자에서 45회 제세동과 장시간의 심폐소생술 시행후 생존한 1례

오세광,조용철,구도현,유승,이진웅,김승환,유인술 대한응급의학회 2008 대한응급의학회지 Vol.19 No.2

The acceptable total number of electrical shocks used in treating cardiac arrest is not exactly defined in any of the literature. It is generally expressed as “the more trials the less chance’’. Electrical therapy should be promptly performed in the presence of “shockable”rhythm. But for pulseless patients bystander cardiopulmonary resuscitation (CPR) should be done on instead. The most reasonable number of attempts of electrical therapy and the length of CPR or unresponsive ventricular fibrillation or pulseless ventricular tachycardia are not well defined. We report the case of 57-year-old woman presenting with mental change due to sustained pulseless ventricular tachycardia who survived to hospital discharge without neurological sequelae after 45 defibrillations and prolonged CPR for 86 minutes.

평간개울지혈탕이(平肝開鬱止血湯) 사염화탄소에(四鹽化炭素) 의한 간기능장애에 대한 영향

吳世光,金宇煥 동의대학교 한의학연구소 1998 동의한의연구 Vol.2 No.-

This study was undertaken to determine if Pyungangaeuljyhyul-tang (PG) has a protective effect against CCL-induced liver cell injury in rabbits. Rabbits were treated intraperitoneally with 0.5㎖/㎏ of CCL₄. In experiments for PG effect, rabbits were pretreated with 2.5 ㎖ of PG for 24 hr before and 24 hr after injection of CCL₄. When rabbits were treated with CCL₄, serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities were increased compared with the control. Such an increase in enzyme activity was significantly inhibited by pretreatment of PG. CCL₄ treatment incrased lipid peroxidation, and its effect was prevented by PG. CCL₄ treatment resulted in a reduction of reduced glutathione (GSH) and an increase of oxidized glutathione (GSSG), which were attenuated by pretreatment of PG. These results suggest that PG could be used in prevention and treatment of drug-induced liver cell injury. However, the precise mechanisms of PG protection remain to be determined.

간질성 경련과 가성 부갑상선 기능저하증을 보인 Fahr’s Syndrome 1례

오세광,이제원,유병대,전덕호,이동하 대한응급의학회 2014 大韓應急醫學會誌 Vol.25 No.5

Fahr’s disease is a rare disease characterized by idiopathicabnormal deposits of calcium in intracranial areas. Fahr'ssyndrome occurs secondarily to other diseases. Endocrinedisorders, particularly parathyroid hormone disorders, aremost commonly associated with Fahr's syndrome. Common clinical features of Fahr's disease or syndromeinclude movement disorder, phychiatric disorder, epilepticseizure, dementia, headache, dystonia, myoclonus, tremor,and parkinsonism. We report on a case of a 35-year-oldwoman with Fahr's syndrome who presented with epilepticseizure and pseudohypoparathyroidism.

전산화단층촬영을 이용한 하대정맥/대동맥 지표와 중심정맥압의 상관관계 - 후향적연구

오세광,조용철,구도현,유승,김승환,유연호,유인술,이진웅 대한응급의학회 2010 대한응급의학회지 Vol.21 No.5

Purpose: To evaluate whether the inferior vena cava/aorta diameter index correlates with central venous pressure (CVP) in the emergency department. Methods: We selected patients who had computed tomography and had their central venous pressure checked between September 2008 and December 2008. Measurement of the IVC and aorta diameters was performed in conjunction with computed tomography. Subjects were divided into two groups: those with a CVP of less than 8 cm H2O (group A), and those with a CVP greater than 8cm H2O (group B). Data collected included the patient's age, sex, height, systolic blood pressure, heart rate, hemoglobin level, IVC diameter and aorta diameter. We analyzed the correlation between the IVC/aorta index and the CVP. Results: A total of 80 patients were enrolled in the study. Of the 80, 39 patients were assigned to group A and 41 to group B. The mean IVC diameter in group A was 14.98±2.58 mm; in group B it was and 18.84±3.01 (p<0.01). The IVC/aorta index in group A was 0.72±0.12; in group B it was 0.96±0.20 (p<0.01). The correlation coefficient for CVP and IVC was 0.72 (p<0.01); for CVP and aorta it was -1.5 (p=0.17); for CVP and the IVC/aorta index it was 0.69(p<0.01)Conclusion: The IVC/aorta index is related to the CVP. There is a difference in the IVC diameter and IVC/aorta index between groups A and B. The IVC/aorta index may be a predictor of body fluid status in the emergency department.

자아주관의 내용과 방법연구 : 문선명 선생의 유·청소년기 삶을 중심으로

오세광 선문대학교 신학대학 2002 선문대학교 신학대학논문집 Vol.2002 No.-

문선명 선생의 말씀선집을 중심한 '참부모님의 생애노정 1권'과 '우주주관 바라기 전에 자아주관 완성하라'를 위주로 연구되었다. 자아주관 완성을 위한 구체적인 실천방안은 계속해서 연구되어야할 과제로 남겨두고 본 논문에서는 자아주관 완성을 위한 모델로서 문선명 선생의 유·청소년기 삶과 자아주관에 관련된 문선명 선생의 말씀을 제시하는데 그 제한 범위를 두고자 한다. Estimation of noise level of a cross flow fan with a simplified vortex wall and a stabilizer has been carried out in this work. Main emphasis lies on the measurements of noise level by using static pressure obtained from pressure transducers connected to pressure taps on the walls of the blowing system. The present method measuring noise of system is relatively easy and does not need expensive facilities for the purpose. The comparison of the present data with the output obtained in an anechoic chamber shows that the two results are qualitatively in good agreements except for the range of low frequency. The discrepancy between the two data is due to the characteristics of noise level based on thermodynamic pressure of fluid flows. It is obtained that noise level arisen from static pressure of flows excludes structure-borne noise such as sound from electric motor and the brackets. In addition, pressure of stable flows accurately describes the noise level rather than the pressure in unstable flow region. Details of flow and noise are presented in series of proper figures and plots.

치과진료실에서의 감염방지

오세광 대한치과의사협회 1998 대한치과의사협회지 Vol.36 No.12

Secondary hypoxic ischemia alters neurobehavioral outcomes, neuroinflammation, and oxidative stress in mice exposed to controlled cortical impact

오세광,박현정,Gyeong-Gyu Yu,정성해,이석우,김훈 대한응급의학회 2021 Clinical and Experimental Emergency Medicine Vol.8 No.3

Objective Hypoxic ischemia (HI) is a secondary insult that can cause fatal neurologic outcomes after traumatic brain injury (TBI), ranging from mild cognitive deficits to persistent vegetative states. We here aimed to unravel the underlying pathological mechanisms of HI injury in a TBI mouse model. Methods Neurobehavior, neuroinflammation, and oxidative stress were assessed in a mouse model of controlled cortical impact (CCI) injury followed by HI. Mice underwent CCI alone, CCI followed by HI, HI alone, or sham operation. HI was induced by one-vessel carotid ligation with 1 hour of 8% oxygen in nitrogen. Learning and memory were assessed using the novel object recognition test, contextual and cued fear conditioning, and Barnes maze test. Brain cytokine production and oxidative stress-related components were measured. Results Compared to TBI-only animals, TBI followed by HI mice exhibited significantly poorer survival and health scores, spatial learning and memory in the Barnes maze test, discrimination memory in the novel object recognition test, and fear memory following contextual and cued fear conditioning. Malondialdehyde levels were significantly lower, whereas glutathione peroxidase activity was significantly higher in TBI followed by HI mice compared to TBI-only and sham counterparts, respectively. Interleukin-6 levels were significantly higher in TBI followed by HI mice compared to both TBI-only and sham animals. Conclusion Post-traumatic HI aggravated deficits in spatial, fear, and discrimination memory in an experimental TBI mouse model. Our results suggest that increased neuroinflammation and oxidative stress contribute to HI-induced neurobehavioral impairments after TBI.

수영 중에 벼락두통을 호소한 가역성 뇌혈관 수축 증후군 1례

오세광,유병대,전덕호,이동하,김기환 대한응급의학회 2018 대한응급의학회지 Vol.29 No.1

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by severe thunderclap headache with multifocal segmental vasoconstriction of the cerebral arteries. RCVS can be diagnosed if the cerebral angiogram shows segmental stenosis and spontaneously resolves within weeks to months. RCVS is reversible, but might cause brain lesions such as subarachnoid hemorrhage or cerebral infarction. We report a 45-year-old woman with severe sudden onset frontal headache who was identified with reversible cerebral vasoconstriction syndrome.