호산구농포모낭염 환자에 대한 경구 Naproxen의 임상적 치료 효과

연제호 ( Je Ho Yeon ),윤상웅 ( Sang Woong Youn ),김규한 ( Kyu Han Kim ),조광현 ( Kwang Hyun Cho ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.12

Background: Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of follicular papules and pustules that mainly involve the face. Although various treatments have been attempted for EPF, including systemic and topical steroids, dapsone and indomethacin, there is no consensus on the first choice for treatment. Objective: The purpose of this study was to evaluate the clinical efficacy and safety of naproxen treatment for EPF patients. Methods: We retrospectively reviewed the clinical records of 16 biopsy-proven EPF patients who were treated with naproxen. Initial dose of oral naproxen was 500 mg to 1,000 mg. Therapeutic effects were evaluated by 3 grades: NR (no response), PR (partial remission, >50% improvement), CR (complete remission). Results: Of the 16 EPF patients, 11 patients (69%) showed either complete remission (50%) or partial remission (19%). The median time to response for good responders (CR+PR) was 1.5 weeks. Two patients (13%) had mild gastrointestinal side effects, such as indigestion, but the symptoms disappeared soon after use of a gastrointestinal protectant. Conclusion: Oral naproxen may be an effective and safe treatment modality for EPF. (Korean J Dermatol 2008;46(12):1609∼1614)

Erlotinib (Tarceva(R)) 복용 후 생긴 여드름양 발진 및 조갑주위염

연제호 ( Je Ho Yeon ),민성욱 ( Seong Uk Min ),이동훈 ( Dong Hun Lee ),최유성 ( Yu Sung Choi ),서대헌 ( Dae Hun Suh ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.11

Erlotinib (Tarceva(R)) is a new anti-cancer agent which acts by inhibiting epidermal growth factor receptor (EGFR) signal transduction. It is currently used in the treatment of advanced stage non-small cell lung cancer and pancreatic cancer. We report a case of acneiform eruption and paronychia induced by erlotinib in a 69-year-old man. The patient visited our clinic with multiple erythematous papules and pustules on the face, periungual erythema and pus discharge, xerosis, fissures on the sole. He had taken erlotinib for the treatment of recurred lung cancer for 4 weeks. The skin lesions were partially improved with oral pyridoxine, corticosteroid and topical antibiotics. (Korean J Dermatol 2007;45(11):1180∼1182)

Mibelli형 한공각화증 3예에서 5% Imiquimod 크림의 치료 경험

연제호 ( Je Ho Yeon ),박현선 ( Hyun Sun Park ),조광현 ( Kwang Hyun Cho ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.9

Porokeratosis is a disorder of epidermal keratinization that is histologically characterized by the presence of cornoid lamella. Many treatment modalities have been used, such as, surgical excision, cryosurgery, CO2 laser, oral etretinate, topical 5-fluorouracil and keratolytics. However, universal treatment guidelines have never been established. We tried 5% imiquimod cream on three patients who have porokeratosis of Mibelli which are intractable to other previous treatment modalities. Two of them showed a marked and moderate improvement, respectively. But the third patient exhibited only slight response. Herein we report our treatment experience and review the related literature. (Korean J Dermatol 2007;45(9):942∼946)

정부지출과 정부부채 : 스라피안 초승수 접근법을 도입한 네오 칼레츠키안 성장 모형을 활용한 분석

연제호(Yeon, Je-Ho) 한국경제발전학회 2020 經濟發展硏究 Vol.26 No.1

This paper examines the relationship between fiscal policy, government debt, economic growth and distribution through the neo-Kaleckian growth model, which introduces government spending whose growth rate is an exogenous variable and Harrodian investment adjustment. For this analysis, it is assumed that the government raises funds for government expenditures and interest payments through debt, without imposing taxes. Under this setting, government expenditures will suppress the first instability of Harrod caused by Harrodian investment adjustment, enabling convergence to normal rate of capacity utilization. Therefore, unlike the existing Kaleckian growth models, this model can analyze the fully adjusted long-run state. In the long-run, an increase in government spending growth leads to an increase in growth rate and a decrease in debt ratio. If the latter change is not accepted by the capitalist class, expansionary fiscal policy can be difficult to implement. This implies that the difficulty of fiscal policy aimed at achieving full employment is based on class conflicts over distribution shares, not on increasing debt burden. In addition, wage-led growth and paradox of thrift, which are important implications of the neo-Kaleckian growth model, still hold in terms of level effect. 본 논문은 외생적 증가율의 정부지출과 해로드적 투자 조정을 도입한 네오칼레츠키안 성장 모형을 통해 재정정책과 정부부채, 경제성장과 분배 사이의 관계를 고찰한다. 이를 위해 정부가 조세 없이 정부지출과 이자지급에 필요한 자금을 부채를 통해 마련한다고 가정한다. 이러한 설정 하에서 지속적 증가추세의 정부지출은 해로드적 투자 조정이 야기하는 해로드의 제1불안정성을 억제시켜서 정상 가동률로의 수렴을 가능하도록 만든다. 즉, 기존의 칼레츠키안 성장 모형과 달리 완전히 조정된 장기 상태에 대한 분석이 가능하다. 장기 모형에서 정부지출 증가율의 상승은 성장률의 증가와 부채비율의 감소를 낳는다. 후자의 변화를 자본가 계급이 수용하지 않을 경우 확장적 재정정책은 시행에 어려움을 겪을 수 있다. 이는 완전고용을 목표로 하는 재정정책의 어려움은 부채부담의 증가가 아닌 분배몫을 둘러싼 계급 간 갈등에 기반함을 의미한다. 그 밖에도 장기 모형에서 네오 칼레츠키안 성장 모형의 중요한 함의인 임금주도성장과 절약의 역설은 수준 효과라는 수정된 방식으로 여전히 성립한다.

Dapsone으로 치료한 피부형 결절성 다발 동맥염 5예

연제호 ( Je Ho Yeon ),김병윤 ( Byung Yoon Kim ),박경찬 ( Kyoung Chan Park ),조광현 ( Kwang Hyun Cho ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9

Cutaneous polyarteritis nodosa (PAN) is a benign form of vasculitis of small and medium-sized arteries with chronic benign course without systemic involvement. Corticosteroids are the mainstay of treatment for cutaneous PAN but aspirin and non steroidal anti-inflammatory drugs (NSAIDs) are also used for conservative treatment. We treated five patients with cutaneous PAN using oral dapsone. All patients initially showed good response to dapsone, but exacerbation occurred once the dose of dapsone was tapered or stopped. Patients had mild side effects of dapsone which were hemolytic anemia (4 cases) and abnormal liver function (2 cases). No patient has developed major organ system involvement during 1 to 13 years of follow-up. Instead of using oral Corticosteroid, oral dapsone may be an effective and relatively safe alternative therapy for chronic benign cutaneous PAN. (Korean J Dermatol 2008;46(9): 1240~1244)

적립식 연금제도: 자본논쟁에 비춘 비판

박만섭(Park,Man-Seop),연제호(Yeon,Je-Ho) 한국사회경제학회 2016 사회경제평론 Vol.29 No.1

This paper looks critically, in the light of the Capital Controversies of the 1950s and the 1960s, at the Neoclassical claim that the Funded-Pension system is economically superior to the Pay-As-You-Go (PAYG) pension system. This claim rests crucially upon the inverse relation between the rate of interest and the volume of investment (the investment demand function) and the positive relation between the capital intensity and labour productivity (the ‘intensive- form’ production function), The Capital Controversies proved that the two relations do not always hold; then, the claim in question loses much of its ground. Further, the absensce of the relations makes plenty room for effective demand in determining the level of income and the volome of employment even in the long period. This positive role of effective demand in the long period highlights the problems of the Funded-Pension system and, at the same time, supports the competitiveness of the PAYG pension system. 이 논문은 부과방식 연금제도에 비한 (완전)적립식 연금제도의 우수성을 주장하는 신고전파 경제학의 관점을 1950-60년대 자본논쟁의 결론에 비추어 비판한다. 문제의 관점은 ‘투자수요함수’와 ‘(집약형) 생산함수’의 형태로 대변되는 관계들, 즉 이자율과 투자 사이의 역관계와 자본집약도와 노동생산성 사이의 정관계에 결정적으로 의존한다. 자본논쟁을 통해 이 두 관계는 항상 성립하는 관계가 아님이 밝혀졌다. 따라서 신고전파 경제학이 주장하는 적립식 연금제도의 우수성은 그 이론적 기반이 약화된다. 또한 그 관계들이 성립하지 않으면, 장기에서도 유효수요가 소득과 고용량을 결정하는 요소로서 작동할 여지가 생긴다. 장기에서 유효수요의 역할은 적립식 연금제도의 문제점을 부각시키는 동시에 부과방식 연금제도의 경쟁력을 지지한다.

연금제도와 사회적 연대

박만섭 ( Man Seop Park ),연제호 ( Je Ho Yeon ) 고려대학교 한국사회연구소 2015 한국사회 Vol.16 No.2

복지프로그램 개혁의 틀 하에서 세계은행이 제시하는 연금개혁의 주요 내용은 바로 부과방식 연금제도의 적립식 연금제도로의 변화와 사적 연금 역할의 증대이다. 이 논문은 부과방식과 적립식 연금제도가 사회적 연대에 어떠한 영향을 끼치는지를 고찰한다. 근대적 연대는 인민주권으로서의 근대적 민주주의와 밀접한 연관을 갖는데 이의 실현은 두 가지 현실적 문제에 직면한다. 독자적 개인들을 어떻게 무정부주의적이지 않은 관계로 포섭시킬 것인지, 자본주의의 확산과 사회의 기능적 분화로 인해 발생하는 사회적 배제의 증가를 어떻게 감축시킬 것인지가 바로 그러한 문제들이다. 이의 해결은 근대 헌정국가 틀 하에서의 사회복지국가의 존재를 전제로 한다. 어떠한 복지제도가 사회적 연대를 증진시키기 위해서는 사회적 배제, 즉 사회의 프롤레타리아화를 감소시켜야 하고 이를 위해 운영에 있어서의 사회적 약자들의 정치적 참여를 가능토록 해야 한다. 제도의 특성상 두 가지 측면 모두에서 부과방식이 적립식 연금제도보다 더 우수하다. 특정 기간 세대 간 소득 이전에 기반하는 부과방식 하에서는 개인의 연금의 시장 의존성이 약화된다. 반면 적립식 하에서 개인의 연금은 스스로의 연기금을 매개로 하는 스스로의 저축에 기반하고 연기금은 금융시장에 의존적이기 때문에 시장의존성이 더욱 크다. 또한 연기금은 역사적으로 사회적 배제의 증가를 낳았던 신자유주의적 금융화에 있어 중요한 역할을 담당하였다. 즉, 부과방식이 적립식 연금제도에 비해 사회적 배제의 감소에 더욱 효과적이다. 부과방식 연금제도는 궁극적으로 정치적 의사결정에 의존적이므로 중요한 결정에 있어 개인들의 민주적, 정치적 참여가 가능하다. 이 때문에 사회적 약자의 목소리가 반영될 수 있는 여지가 커진다. 적립식 연금제도 하에서는 연기금의 운영이 소수의 투자전문가에게 위임되고 수익률이 가장 중요한 목표가 되기 때문에 연금제도에 대한 민주적 통제가 약화된다. 또한 적립식 연금제도 하에서 개인들이 스스로를 (금융)투자자로 동일시하는 주체화 과정이 발생하여 연금에 대한 민주적 통제에 대한 개인들의 관심이 더욱 감소할 것이다. 이 때문에 연금제도가 사회적 배제를 방지하는 역할이 약화될 수 있을 것이다. 사회의 프롤레타리아화의 방지, 제도와 민주주의와의 연관성 모두에 있어 부과방식이 적립식 연금제도보다 더욱 우수한 결과를 낳을 수 있는 제도이므로 전자가 사회적 연대 Pension reform proposed by the World Bank under the rubric of reforming the state welfare program consists mainly of change from the Pay-As-You-Go (PAYG) system to the Funded pension system and the increased role of private pensions. This paper investigates how the two different pension systems will affect social solidarity. Modern solidarity is closely related to modern democracy as people’s sovereignty, and its realization is faced with two problems in reality: how to comprise individuals in a non-anarchistic way and how to decrease social exclusions which are on the increase due to the spread of capitalism and the functional diversification of the society. A solution to these problems presupposes the existence of a social welfare state in the modern constitutional framework. That is, a welfare system can promote social solidarity by decreasing social exclusions, which is to say to decrease the proletarianization of the society, and by making possible the political participation of the socially disadvantaged. In both of the above aspects, the PAYG system is superior to the Funded system. The PAYG system, which is based on income transfer between successive generations, has the effect of weakening the dependence of an individual’s pensions on the market; the opposite is the case for the Funded system. Also, the PAYG system has wider room for individuals’ participation in the political processes, as the working of pension in this case ultimately hinges upon political decisions; in contrast, the Funded system, where funds are managed by a few specialists and the rate of return is the highest concern, weakens democratic controls of the pension system. All in all, the PAYG system seems more appropriate to the fundamental aim of the welfare state, which is nothing but to increase social solidarity.

외상후에 생긴 이소성 조갑

김병윤 ( Byung Yoon Kim ),연제호 ( Je Ho Yeon ),민성욱 ( Seong Uk Min ),이동훈 ( Dong Hun Lee ),서대헌 ( Dae Hun Suh ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.4

Ectopic nail is characterized by growth of nail-like tissue in a location other than the nail bed. It is an extremely rare disorder that can be either congenital or acquired from incidents such as trauma. An 8-year old female presented with a complaint of a nail-like lesion on the dorsal surface around the center of the right fifth toe. It had been present for 3 years, while the patient continuously clipped it upon growth. The fifth toe was initially injured by a chair that had fallen on that toe 4 years prior to her visit. There was no associated bony deformity or other physical changes in the nail. A clinical diagnosis of ectopic nail was made and it was surgically excised under local anesthesia. The histopathological examination revealed a normal nail unit and there was no recurrence during the 6 month follow-up period. (Korean J Dermatol 2009;47(4):491~493)

비침습적 생체공학 방법으로 측정한 정상 몽골인 피부의 생리적 특성

나르만다흐 ( Narmandakh Jugee ),전혜찬 ( Hye Chan Jeon ),연제호 ( Je Ho Yeon ),백승환 ( Seung Hwan Paik ),최재우 ( Jae Woo Choi ),박영운 ( Young Woon Park ),은희철 ( Hee Chul Eun ),권오상 ( Oh Sang Kwon ),서정선 ( Jeong Sun Seo ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.5

Background: Physiological parameters of the skin measured by non-invasive methods have been considerably developed. It is known that there are some differences in physiologic parameters between different races. Objective: The purpose of this study is to understand the differences between the races. Methods: A total of 757 Mongolian participated in this study. All subjects had no major history of skin diseases requiring medical treatment. Several instruments were used such as Sebumeter, Corneometer, Mexameter for measuring sebum excretion rate, values of capacitance, melanin index and erythema index respectively. These were measured on various areas of the skin such as cheek, forehead, palm, outer arm, inner arm, back and buttock. Results: The sebum excretion rates showed higher in males than in females on the cheek and forehead in Mongolian. However, they showed higher in the females on the palm. There were good correlation between the skin sebum level and the capacitance in males and females. The melanin index and erythema index showed higher in males than in females at all sites. When we compared this with the data published in other countries, many data were similar to Korean rather than a western country`s. However, the capacitance data were lower than those of Korean. Conclusion: Although, this study has some limit for direct comparison between each race, our results can be used as basic data for the comparison between Mongolian and other races in the future. (Korean J Dermatol 2012;50(5):413∼418)