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여인범,민승기,오승환,권경환,최상문,박상규,Yeo, In-Bum,Min, Seung-Ki,Oh, Sung-Hwan,Kwan, Kyung-Hwan,Choi, Sang-Moon,Park, Sang-Kyu 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.6
According to the development of operation technique and biologic materials, oromaxillofacial surgery department have used many kinds of metal and biologic materials in ORIF and plastic surgery. In maxillofacial fracture, ORIF with metal plate and screw have short healing period and good prognosis. But ORIF with metal materials have many complications as maxillofacial abnormal growth, screw loosening, bone malunion. And metal materials have not used in infection site. The purpose of this study is to evaluate the clinical value of 10 condylar fracture patients operated with absorbable screw at Wonkwang university. Ten patients(8 males, 2 female, mean aged 28) who had mandibular condyle process fracture treated with PLLA implants(poly-l-lactide) was recalled for follow-up clinical and radiologic examination for 10 years. Mouth opening recorvered to more than 35mm and occlusion was stable in all patients. All fractured mandibular condyles showed anatomic good reduction and long-term stability with the use of resorbable miniplates and screw. Bone healing was satisfactory in all patients, and there was no evidence of abnormal resorption of condylar process.
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가토의 상악동 골이식술시 미분화 간엽 줄기세포의 골형성 효과
오승환,채영원,김범수,여인범,조필귀,Oh, Sung-Hwan,Choi, Young-Won,Kim, Bum-Soo,Yeo, In-Bum,Jo, Pil-Kwy 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.6
Undifferentiated mesencymal stem cells(UMSCs) have been thought to be multipotent cells that can replicate as undifferentiated cells and that have the potential to differentiate into lineages of mesenchymal tissue including the bone, cartilage, fat, tendon, muscle, and marrow stroma. It can be used to sinus lifting, Guided bone regeneration, other bone graft in dental part. The purpose of this study is to evaluate the effect of mesencymal stem cells on sinus augmentation with autogenous bone, fibrin glue mixture in a rabbit model. 8 New Zealand white rabbits were divided randomly into 4 groups based on their time of sacrifice(1, 2, 4 and 8 weeks). First, undifferentiated mesenchymal stem cells were isolated from iliac crest marrow of rabbits and expanded in vitro. cell culture was performed in accordance with the technique described by Tsutsumi et al. In the present study, The animals were sacrificed at 1, 2, 4 and 8 weeks after transplantation, and the bone formation ability of each sides was evaluated clinically, radiologically, histologically and histomorphologically. According to the histological observations, Stem cell group showed integrated graft bone with host bone from sinus wall. At 2 and 4weeks, It showed active newly formed bone and neovascularization. At 8 weeks, lamella bone was observed in sinus graft material area. Radiologically, autobone with stem cell showed more radiopaque than autobone without stemcell. there were significant differences in bone volume between 2 and 4 weeks (p<0.05). In summary, the autobone with stem cells had well-formed, newly formed bone and neovasculization, compared with the autobone without stem cells (esp. 2 weeks and 4 weeks) The findings of this experimental study indicate that the use of a mixture of mesenchymal stem cell yielded good results in osteogenesis and bone volume comparable with that achieved by autogenous bone. Therefore, this application of this promising new sinus floor elevation method for implants with tissue engineering technology deserves further study.
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서정숙(Jeong Sook Suh),방병호(Byung Ho Bang),여인범(In Beop Yeo) 한국식품영양학회 2001 韓國食品營養學會誌 Vol.14 No.2
종합병원에 근무하는 여자직원들을 대상으로 건강 한 사람 11명과 체질량지수 25이상인 7명을 선정하여 4 주간의 발아생식을 섭취한 후 인체 계측과 혈당, 혈청 지방질 변화를 보기 위해 triglycerides, total cholesterol, HDL-cholesterol을 측정하여 다음과 같은 결과를 얻었다. 1. 4주간 발아생식을 섭취한 후 비비만군의 평균체중은 54.2kg에서 51.7kg으로 (p<0.001) 비만군은 평균체중 69.1kg에서 65.6kg으로 (p<0.001) 모두 유의적 감소율을 보였다 . 2. 피하지방 두께 변화는 삼두박근의 경우 비비만군 에서 21.6mm에서 19.95mm로, 비만군에서도 35.4 mm에서 32.1mm로 모두에서 유의적인 감소를 보였다. (P<0.0l, P<0.05) 또한 신체둘레에 있어서 는 허리둘레가 비비만군이 69.7cm에서 66.8 cm로 현저히 감소하였고 (p<0.0001) 비비만군도 84.2cm에서 80cm로 감소하여 유의성을 보여 (P< 0.017), 발아생식은 복부비만자에게 효과가 있다고 생각 된다. 3. 비만군, 비비만군 모두 혈당, triglycerides, total cholesterol의 감소를 가져왔고, HDL-cholesterol은 비비만군에서 3.3%, 비만군에서 5.8%의 상승을 보였다. 이상의 결과에서 4 주간 발아생식을 섭취한 후에 체중과 피하지방 두께의 감소, 혈당 및 혈청지방질 성분 이 개선된 것을 볼 수 있었다. 발아생식 제품은 고른 영양소를 함유하여 일상생활에 무리를 주지 않는 범 위내에서 체중감량과 혈액 조성이 이상적으로 유도되어감을 보여주는 다이어트식이임을 알 수 있었다. 이 는 비만으로 동반될 수 있는 당뇨병이나 동맥경화, 심장병, 고혈압, 통풍 등 혈액질환이나 고지혈증과 같은 만성적인 부작용까지도 극복하고 개선될 수 있는 새로운 비만개선 식이로써 좀더 안전하고 효율적인 다이어트를 위한 식품의 개발에 활용될 것을 기대한다. 특히 발아생식을 실시했을 때 복부 비만자에게서 허리둘레, 엉덩이둘레가 현저히 감소되었다. This study was carried out to investigate the effect of weight loss and the change of serum lipids composition for normal and obese women after sprout raw grains and vegetables diet intake. Diet were given to the subjects which were composed of 11 normal women and 7 obese women for 4 weeks. After diet intake, 4.6% in normal group and 3.5% in obese group were shown weight loss. And the both groups of normal and obese women showed a significant reduction in the thickness of subcutaneous fat and the body girth. Particularly, the waist measure was shown to be remarkably reduced in the normal group (p<0.0001) and to be reduced in the obese group (p<0.017) significantly. After diet intake, the levels of total cholesterol and triglycerides were reduced in both groups significantly. And in the obese women, HDL-cholesterol level increased 5.7%. As those results, it could be seen that weight and the thickness of subcutaneous fat were reduced and the component of blood serum were improved after diet intake for 4 weeks. Specially, abdomen, waist measures and hip girth were reduced remarkably, so it is considered that the diet is more effective in the diet therapy of obese women with upper obese status.
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