무우자갈버섯(Hebeloma crustulineforme)을 위시한 한국산 담자균류 46종의 용혈활성 검색

양희정,정수현,김진향,정경수 충남대학교 약학대학 의약품개발연구소 1997 藥學論文集 Vol.13 No.-

To elucidate the hemolytic toxicities of Korean basidiomycetes, the cold-water extracts of 46 wild mushrooms were tested for hemolytic activity on mouse erythrocytes. Twelve species including Amanita esculenta, A. griseofarinosa, A. longistriata, A. melleicepe, A. phalloides, A. rubescence, A. spissacea, A. vaginata, Hebeloma crustuliniforme, Lepiota cygnea, Macrolepiota procera, and Oudemansiella platyphylla showed strong hemolytic activities. Of these, A. griseofarinosa and H. crustuliniforme showed no decrease in their hemolytic activity even after five minutes' boiling.

빛간섭단층혈관조영술을 이용하여 측정한 백내장수술 전후 망막중심오목무혈관부위의 변화

양희정,김기석 대한안과학회 2020 대한안과학회지 Vol.61 No.5

Purpose: To report changes in the foveal avascular zone (FAZ) after uncomplicated cataract surgery using optical coherence tomography (OCT) angiography. Methods: The present study evaluated 39 eyes that underwent cataract surgery between April 2019 and June 2019. Central macular thickness (CMT) and subfoveal choroidal thickness (SFCT) were measured by OCT. The area of the FAZ in the superficial vascular complex (SVC) and deep vascular complex (DVC) were measured using OCT angiography. Results: In all eyes, except for five with cystoid macular edema, there was a statistically significant change in the CMT over time (p < 0.0001), and the CMT at 1 month postoperatively was significantly thicker than the preoperative CMT (p = 0.005). The SFCT was significantly thicker at 1 week and 1 month postoperatively relative to the preoperative values (p < 0.0001 and p = 0.004, respectively). The FAZ area in the SVC and DVC decreased significantly at 1 week and 1 month postoperatively compared with the preoperative values (p < 0.0001 and p = 0.007, respectively). In the five eyes that developed cystoid macular edema, the area of the FAZ in the DVC showed a significant increase at 1 month postoperatively compared with the preoperative value (p = 0.028). Conclusions: The FAZ area in the SVC and DVC decreased postoperatively, suggesting that cataract surgery may affect perfusion in the macula. 목적: 빛간섭단층혈관조영술을 이용하여 백내장수술 전후 망막중심오목무혈관부위의 변화에 대하여 알아보고자 하였다. 대상과 방법: 2019년 4월부터 2019년 6월까지 본원에서 백내장수술을 받은 39명 39안의 의무기록을 후향적으로 조사하였다. 술 전, 술 후 1주일, 술 후 1개월에 빛간섭단층촬영을 이용하여 중심황반두께 및 중심와밑 맥락막두께를 측정하였으며 빛간섭단층혈관조영술을 이용하여 표층혈관총과 심층혈관총에서의 망막중심오목무혈관부위의 면적을 측정하였다. 결과: 총 39안 중 낭포황반부종이 발생한 5안을 제외한 34안의 중심황반두께는 시간에 따른 유의한 변화가 있었으며(p<0.0001) 술 후 1개월에 술 전보다 유의하게 증가하였다(p=0.005). 중심와밑 맥락막두께는 시간에 따른 유의한 변화가 있었으며(p<0.0001) 술 후 1주일, 술 후 1개월에 술 전보다 증가하였다(p<0.0001, p=0.004). 표층혈관총과 심층혈관총의 망막중심오목무혈관부위의 면적 역시 시간에 따른 유의한 변화가 있었으며(p<0.0001), 술 후 1주일에 술 전보다 감소한 소견을 보였다(p<0.0001, p=0.007). 낭포황반부종이 발생한 5안에서 망막중심오목무혈관부위의 면적은 심층혈관총에서 시간에 따른 유의한 변화를 보였으며(p=0.028) 술 후 1개월에 술 전보다 증가하는 양상을 보였다. 결론: 백내장수술 후 표층 및 심층혈관총에서 중심오목무혈관부위의 감소 소견이 관찰되었다. 이는 백내장수술 후 회복 과정에서 황반 중심와의 관류에 변화가 있을 수 있음을 시사한다.

Alternating and Relapsing Migratory Orbital Myositis

양희정,신희정,백지선,양석우 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.6

A.4 : 품질관리 : A.4.3 ; ISO20000 인증에 대한 정량적인 효과 분석

양희정 한국품질경영학회 2012 한국품질경영학회 학술대회 Vol.2012 No.1

메이지초기 서양예능의 도입과 전통예능에 미친 영향: ‘서양인 서커스단’의 사례를 중심으로

양희정 일본사학회 2018 일본역사연구 Vol.48 No.-

The process of circus was introduced into Japan during the Meiji period is interesting. This was based on the traditional Japanese amusement called Misemono(見世物). At first, this was called “Western Kyokuba(西洋曲馬)” because it was similar to Kyokuba(曲馬), which means Japanese acrobatics using horsemanship. However, circus was one of the undoubted Western cultures that flown into Japan through the Japanese entertainment of the Western circus. When the circus was introduced, a residence scheme regulation existed in Japan. Under this system, foreigners were only allowed to live within designated areas (foreign settlement). However, places where Misemono was performing mainly in Tokyo were out of the foreign settlement such as Asakusa. This was an obstacle for Western entertainers to enter Japan. However, the Meiji government’s ‘Civilization and Enlightenment(文明開化)’ policy was focused on adopting Western civilization, and eventually the Western circus culture overcame the foreign concession residence scheme regulation. By the 1880s it was prominent that the residence scheme regulation eased off. The circus became a big hit; Japanese circus troupe was formed and settled in Japanese society. Conversely, the popularity of traditional Japanese amusement declined. In conclusion, it would be possible to reevaluate the characteristics of the Meiji period in consideration of the Western circus culture influx. The acceptance of Western culture requires slow progress and conflict between tradition and Western culture in society.

A Family with Axenfeld-Rieger Syndrome: Report of the Clinical and Genetic Findings

양희정,이유경,주천기,문정일,목지원,박명희 대한안과학회 2015 Korean Journal of Ophthalmology Vol.29 No.4

Purpose: To describe clinical findings in a Korean family with Axenfeld-Rieger syndrome. Methods: A retrospective review of clinical data about patients with diagnosed Axenfeld-Rieger syndrome. Five affected members of the family underwent a complete ophthalmologic examination. We screened the forkhead box C1 gene and the pituitary homeobox 2 gene in patients. Peripheral blood leukocytes and buccal mucosal epithelial cells were obtained from seven members of a family with Axenfeld-Rieger syndrome. DNA was extracted and amplified by polymerase chain reaction, followed by direct sequencing. Results: The affected members showed iris hypoplasia, iridocorneal adhesions, posterior embryotoxon, and advanced glaucoma in three generation. None had systemic anomalies. Two mutations including c.1362_1364insCGG and c.1142_1144insGGC were identified in forkhead box C1 in four affected family members. Conclusions: This study may help to understand clinical findings and prognosis for patients with Axenfeld-Rieger syndrome.

사과 겹무늬썩음병에 걸린 가지로부터 분산되는 병포자의 정량적 조사법 개발

양희정,최창희,우현,김대희,엄재열,Yang, Hee-Jung,Choi, Chang-Hee,Woo, Hyun,Kim, Dai-Hee,Uhm, Jae-Youl 한국식물병리학회 1998 Plant Pathology Journal Vol.14 No.4

On the basis of the fact that the pycnidiospore of Botryosphaeria dothidea, the causal fungus of apple white rot is a typical water borne spore, a method for quantitative analysis of pycnidiospore dispersal from the warts produced on the diseased apple tree stem was developed. The warts on which cracks developed either on or around them were cut off at the base, and shaked in the water for 4hours at 2$0^{\circ}C$, in which condition the maximum number of spores were released. The volume of shaking solution was calculated as 1 ml per one wart. At the end of shaking, Trio, a household detergent was added to the shaking solution to the concentration of 0.1%, and shaked for additional 10 minutes at 35$^{\circ}C$ to take off the spores attached on the glass ware. One milliliter of the spore suspension thus prepared were passed through transparent membrane filter (pore size : 3.0 ${\mu}{\textrm}{m}$), and the spores attached on the filter were counted under a microscope ($\times$200) after staining them with lactophenol supplemented with aniline blue. The results thus obtained were statistically consistent when at least 30 warts were used simultaneously in single shaking. This method can be applicable in the elucidation of ecology of sporulation and spore dispersal, and also in the screening of the sporulation inhibitor which can be used in the control of the disease by reducing the inoculum density.

국내 미출간 해외도서 review

양희정,Yang, Hui-Jeong 대한출판문화협회 2003 출판저널 Vol.334 No.-

Cu oxide의 형성과 H(hfac) 반응을 이용한 Cu 박막의 건식식각

양희정,홍성진,조범석,이원희,이재갑,Yang, Hui-Jeong,Hong, Seong-Jin,Jo, Beom-Seok,Lee, Won-Hui,Lee, Jae-Gap 한국재료학회 2001 한국재료학회지 Vol.11 No.6

Dry etching of copper film using $O_2$ plasma and H(hfac) has been investigated. A one-step process consisting of copper film oxidation with an $O_2$ plasma and the removal of surface copper oxide by the reaction with H(hfac) to form volatile Cu(hfac)$_2$ and $H_2O$ was carried but. The etching rate of Cu in the range from 50 to 700 /min was obtained depending on the substrate temperature, the H(hfac)/O$_2$ flow rate ratio, and the plasma power. The copper film etch rate increased with increasing RF power at the temperatures higher than 215$^{\circ}C$. The optimum H(hfac)/O$_2$ flow rate ratio was 1:1, suggesting that the oxidation process and the reaction with H(hfac) should be in balance. Cu patterning using a Ti mask was performed at a flow rate ratio of 1:1 on 25$0^{\circ}C$\ulcorner and an isotropic etching profile with a taper slope of 30$^{\circ}$was obtained. Cu dry patterning with a tapered angle which is necessary for the advanced high resolution large area thin film transistor liquid-crystal displays was thus successfully obtained from one step process by manipulating the substrate temperature, RF power, and flow rate ratio.

Determination of five active compounds in Artemisia princeps and A. capillaris based on UPLC-DAD and discrimination of two species with multivariate analysis

양희정,이동영,전민지,서영배,성상현 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.5

Five active compounds, chlorogenic acid,3,5-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid,jaceosidin, and eupatilin, in Artemisia princeps (Compositae)were simultaneously determined by ultra-performanceliquid chromatography connected to diode array detector. The morphological resemblance between A. princeps andA. capillaris makes it difficult to properly identify speciesproperly. It occasionally leads to misuse or misapplicationin Korean traditional medicine. In the study, the discriminationbetween A. princeps and A. capillaris was optimallyperformed by the developed validation method, whichresulted in definitely a difference between two species. Also, it was developed the most reliable markers contributingto the discrimination of two species by the multivariateanalysis methods, such as a principal componentanalysis and a partial least squares discrimination analysis.