http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
만삭산모에서 유도분만의 성공예측지표로서 질식초음파를 이용한 자궁경부 관찰의 유용성
양순하(Soon Ha Yang),오정미(Jung Mi Oh),노정래(Cheong Rae Roh),정재현(Jae Hyun Chung) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.11
N/A Objectives: The purposes of this study were to determine the usefulness of transvaginal ultrasonographic assessment of the uterine cervix and to compare the diagnostic performance of ultrasonographic and digital examination of the cervix in predicting a successful induction of labor. Study design: One hundred-one singleton term pregnancies without ruptured membranes admitted for the labor induction were included in this study. Digital examination and transvaginal ultrasonography of the uterine cervix were performed at the time of admission. Cervical parameters evaluated included cervical length, presence of funneling, funnel length, and funnel width. Labor induction was underwent by prostaglandin E2 (PGE2) vaginal suppository and/or pitocin intravenous infusion. Outcome variable was a successful labor induction within 48 hours after beginning of the induction. Results: The prevalence of induction failure was 10.9% (11/101). Receiver-operator characteristic (ROC) curve and multiple logistic regression analysis indicated a significant relationship between the successful induction of labor and cervical length <3.1 cm. The diagnositic indices of endocervical length was superior to those of Bishop's cervical score in predicting a successful induction of labor. In patients with cervical length <3.1 cm, the labor was induced successfully with fewer tablets of PGE2, less use of pitocin infusion, and shorter induction-delivery interval. Conclusion: Transvaginal ultrasonographical examination of the uterine cervix is more accurate than digital examination of the cervix in the prediction of a successful induction of labor in term gestation.
DNA분석에 기포한 표피박리성 수장족저 각피증 ( Epidermolytic palmoplantar keratoderma ) 의 산전 진단
양순하(Soon Ha Yang),노정래(Cheong Rae Roh),이제호(Je Ho Lee),정재현(Jae Hyun Chung),문종수(Zong Soo Moon),양준모(Jun Mo Yang),김승욱(Syng Wook Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.1
N/A Objective: The purpose of this investigation was to establish the prenatal diagnosis for identifying the risk for epidermolytic palmoplantar keratoderma(EPPK) of a fetus by sequence analysis of fetal genomic DNA from chorionic villi. Methods: Chorionic villus sampling under transvaginal sonography at 12 weeks of gestation from a woman at risk for a child in a EPPK-affected family was perfomed. Polymerase chain reaction amplification of specific allele (PASA) assay was carried out for the detection of mutation(R162W in keratin 9 [K9] gene) previously identified in this family. Direct DNA sequencing analysis of K9 gene was accomplished to confirm the mutation. Results: We had found the point mutation, R162W of K9 gene, in affected family members and confirmed by PASA assay. Affected family members were shown to have PCR products reactive with both the mutant and wildtype specific primers. Because we could not find any expected products after PASA assay with the primers la(+)/KSmt(-) of the fetal DNA, we predicted that the fetus did not inherited the mutant allele and that the fetus could be unaffected. After PASA assay, we analyzed DNA sequences of two family members to confirm the mutation. A C-to-T substitution at bp 545 was detected in the father, instead the fetus did not have any mutant band at that base pair. Conclusion: The PASA assay and direct DNA sequencing analysis of K9 gene through chorionic villi sampling and extraction of genomic DNA had validity to early prenatal diagnosis whether fetus was affected in EPPK or not.
자궁경부의 개대가 진행된 자궁경부무력증에서 응급 자궁경부봉축술의 유용성
양순하 ( Soon Ha Yang ),김지운 ( Ji Un Kim ),최성진 ( Seong Jin Choi ),서용수 ( Yong Soo Seo ),김영아 ( Young Ah Kim ),김종화 ( Jong Hwa Kim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3
목적 : 자궁경부무력증이 의심되는 임신중기의 임신부에서 자궁경부의 개대가 진행된 경우에서 시행한 응급 자궁경부봉축술이 임신 경과와 주산기 예후에 어떤 영향을 미치는지를 알아보고자 하였다. 연구 방법 : 1995년 3월부터 2001년 6월까지 삼성서울병원에서 응급 자궁경부봉축술을 시행받은 16명의 환자에서 임신부와 신생아의 의무기록을 조사하여 임신경과 및 신생아 예후를 분석하였고 이를 같은 시기에 정규 자궁봉축술을 시행받은 48명의 환자의 기록과 비교하였 Objective : To investigate the clinical significance of emergency cerclage on prologation of pregnancy and perinatal outcome in mid-trimester cervical incompetence with advanced cervical dilatation. Methods : We analyzed the pregnancy outcome retrospectiv
만삭 자궁근세포에서 염증성 사이토카인에 의한 nuclear factor-kappa B 활성화 양상의 진통 유무에 따른 차이 비교
양순하 ( Soon Ha Yang ),신희철 ( Hee Chul Syn ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.3
목적: 본 연구는 만삭의 자궁근세포에서 염증성 사이토카인 (pro-inflammatory cytokines)을 처리하였을 때 제2형 순환산화효소 (cyclooxygenase-2, 이하 COX-2)의 발현과 프로스타글란딘 (prostaglandin, 이하 PG) 생성이 유도되는 과정이 전사인자 nuclear factor-κB (이하 NF-κB)의 매개에 의함을 관찰하고, 그 양상을 진통의 유무에 따라 비교함으로써 사이토카인의 유도에 의한 NF-κB의 매개 Objective: The objectives of this study were to determine whether NF-κB-mediated pro-inflammatory cytokines signaling leads to COX-2 expression and PGE2 synthesis in human myometrial cells at term, and to compare cytokines-induced NF-κB activity and subse