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양수인,김재영,좌혜정 연세대학교의과대학 2014 Yonsei medical journal Vol.55 No.1
Purpose: The aim of the present study was to evaluate the clinical characteristics of the primary Epstein-Barr virus (EBV) hepatitis with elevation of both serum alkaline phosphatase (ALP) and γ-glutamyltransferase (γ-GT) levels in children. Materials and Methods: A retrospective study was performed by reviewing of the medical records of 36 patients who were diagnosed with primary EBV hepatitis. The patients were divided into 2 groups: patients with elevated serum ALP and γ-GT levels (group 1) and patients without (group 2). Results: The classic features of infectious mononucleosis (fever, pharyngitis and/or tonsillitis, and cervical lymphadenitis) were seen in 20 (57.1%) of group 1 patients and 18 (50.0%) of group 2 patients. Hepatitis with elevated serum ALP and γ-GT levels were present in 14 (38.9%) of the all patients. Of these patients, Jaundice occurred in only 2 (5.6%). The mean levels of aspartate aminotransferase and alanine aminotransferase (ALT) as well as the number of patients with ALT greater than 400 IU/L were significantly different between the groups (177 IU/L vs. 94 IU/L, 418 IU/L vs. 115 IU/L, and 50.0% vs. 13.6%; p=0.001, p=0.001, p=0.026, respectively). The mean duration of elevated serum ALT levels was 17.5 days in group 1 and 9.0 days in group 2 (p=0.013). All patients recovered fully without any chronic or serious complications. Conclusion: Primary EBV hepatitis with predominant biochemical abnormalities of the elevation of ALP and γ-GT is frequent and mostly anicteric. This may represent a benign disease, but a delay in recovery of liver function as well.
양수인,서승미,노은정,류재기,류경열,정규석 한국식품위생안전성학회 2019 한국식품위생안전성학회지 Vol.34 No.6
This study assessed microbial contamination of leeks and leek-cultivated soil. Leeks and leek-cultivated soil were collected in A and B regions and accounted for 39 and 33 samples, respectively. All of the samples were analyzed for the presence of sanitary indicator bacteria (total aerobic bacteria, coliforms and Escherichia coli), Salmonella spp., E. coli O157:H7, Listeria monocytogenes, and Bacillus cereus. In A and B region, the total aerobic bacteria was in the range of 5.87-8.78 log CFU/g for leeks and 5.94-8.45 log CFU/g for leek-cultivated soil. The coliform in leeks and leek-cultivated soil was in the range of 1.20-7.36 log CFU/g and 2.45-5.87 log CFU/g, respectively. B. cereus was detected from some of the samples while other pathogens were not detected. This study provides important background information on the microbiological safety of fresh vegetable cultivation environments.
양수인,위인선,이종빈 ( Soo In Yang,In Sun Wui,Jong Bin Lee ) 한국환경생물학회 1993 환경생물 : 환경생물학회지 Vol.11 No.1
Toxic effects of Hg^2+, Cd^2+ and Cr^6+ on developing chick embryos were examined by injecting the metal ions (1, 5, 10 and 50㎍ of each in saline solution) into yolk sac of fertilized egg. The injections were performed just before 3 days or 6 days after incubation. It was investigated on the enzyme activities (LDH, MDH, SDH) in liver, heart and pectoral muscle at 14 days after incubations. 1. The degree of decrease in the activities of LDH and MDH were greater than that of SDH. The relative sensitivity of the enzymes was MDH > LDH > SDH. 2. The toxicity of the metal inos is more heavy at early embryonic stage. The relative toxic effect of the metal inos was Cd^2+>Cr^6+>Hg^2+. 3. The relative sensitivity of tissues on the metal ions was liver > pectoral muscle > heart.