천골의 세침흡인검사로 진단된 전이성 간세포암종

심정원,고일향,Shim, Jung-Weon,Ko, Ill-Hyang 대한세포병리학회 1990 대한세포병리학회지 Vol.1 No.2

Bone metastasis of hepatocellular carcinoma appears to be peculiar when clinical manifestation of liver disease is not apparent, and initial diagnosis of metastatic hepatocellular carcinoma by fine needle aspiration cytology is rarely obtained. We experienced a case of 45-year-old man with metastatic hepatocellular carcinoma in the sacrum, which was diagnosed by fine needle aspiration cytology. The intrahepatic mass, measuring 1.2 cm in diameter and kept unchanged in size for two years, was never proved to be hepatocellular carcinoma histopathologically. The aspirated neoplastic cells were mostly in sheets, showing abundant acidophilic cytoplasm and large, round, centrally located nuclei with single, prominent acidophilic mucleoli. In the cell block section, diagnosis of metastatic well-differentiated hepatocellular carcinoma was made without difficulty, and definite trabecular fashion with sinusoidal endothelial cell lining was found.

갑상선의 여포상 종양의 감별에 있어서 TCM-9의 발현양상

김윤정,심정원,안혜경,박영의,Kim, Yun-Jung,Shim, Jung-Weon,Ahn, Hye-Kyung,Park, Young-Euy 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2

Monoclonal antibody(TCM-9) against human thyroid cancers have been studied by screening with human thyroid cancers, normal and benign thyroid tissue, and normal human serum protein. A monoclonal antibody(TCM-9) that is known to have strong specificity for human thyroid cancer but not for Graves' disease, adenoma or normal thyroid does not bind to native or mature human thyroglobulin(Tg). We used to TCM-9 antibody by immunohistochemical staining on 5 follicular cancer, 2 follicular adenoma, 1 follicular neoplasm with suspicious invasion, 2 papillary cancer to ascertain being of help in differentiation between follicular carcinoma and adenoma. Reactivity of TCM-9 was observed in follicular carcinoma and papillary carcinoma but not observed in follicular adenoma. Thus TCM-9 is a novel monoclonal antibody against the thyroid cancer.

모기질 세포종 - 증례 보고 -

박경미,심정원,고일향,Park, Kyeong-Mee,Shim, Jung-Weon,Ko, Ill-Hyang 대한세포병리학회 1991 대한세포병리학회지 Vol.2 No.2

Pilomatricoma is a well defind and characteristic entity histologically, but this tumor may be encountered during aspiration biopsy of subcutaneous mass, and is, occasionally, confused with other neoplasms, particularly squamous cell carcinoma, basal cell carcinoma, and epidermal inclusion cyst. Recently, we have experienced a case of pilomatricoma diagnosed by aspiration biosy. The smear of the aspirate revealed anucleated "ghost" squamous cells, basaloid or basophilic squamous cells and nucleated squamous cells, which lack nuclear features of malignacy. These findings are consistent with pilomatricoma.

고환백막에서 발생한 평활근종 1례

김형윤,조성태,이영구,김기경,박흥원,양익,Ik Yang 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.5

소아의 직장에서 발생된 단일 선종성용종(isolated adenomatous polyp) 1례 -세관융모성 선종(tubulovillous adenoma)-

김제우,송준영,이해경,윤혜선,양익,심정원,정기섭,김호근,Kim, Je-Woo,Song, Jun-Young,Lee, Hae-Kyoung,Yun, He-Sun,Yang, Ik,Shim, Jung-Weon,Chung, Ki-Sup,Kim, Ho-Keon 대한소아소화기영양학회 1999 Pediatric gastroenterology, hepatology & nutrition Vol.2 No.2

Isolated rectal adenomatous polyp without genetic background is rarely found in children. A 4-year and 5 month-old girl was admitted for intermittent bloody stools lasting 4 months. A $1.5{\times}1.2\;cm$ sized rectal polyp was found by air contrast barium enema. Endoscopic polypectomy was performed without complications. In histopathologic examination, it was found to be a tubulovillous adenoma. Typical radiologic, colonoscopic, and pathological pictures are presented.

고관절 주위 골절 노인 환자에서 대퇴골두 연골의 변성

장준동(Jun-Dong Chang),유제현(Je-Hyun Yoo),이상수(Sang-Soo Lee),심정원(Jung-Weon Shim),김창영(Chang-Young Kim),권순억(Soon-Eok Kwon) 대한정형외과학회 2006 대한정형외과학회지 Vol.41 No.2

목적: 고관절 주위 골절이 있었던 노인 환자에서 대퇴골두의 관절 연골의 변성 정도를 육안적, 조직학적, 면역 조직 화학적 소견을 통해 평가해 보고자 하였다. 대상 및 방법: 고관절 주위 골절로 양극성 반치환술을 시행 받은 65세 이상 환자 중 수상 전에 고관절부 동통없이 보행이 가능하고 술 전 단순 방사선 사진상 퇴행성 변화가 없었던 30예를 대상으로 하였고, 평균 나이는 79.7세 (65-94)였다. 육안적 소견은 술 중 적출된 대퇴골두의 체중 부하부위 3구역(전상, 중상, 후상방) 및 비체중 부하 부위 1구역(하방)에서 시행한 후, 총 4구역에서 연골하골을 포함한 관절 연골을 채취하여 Hematoxylin & Eosin 염색 및 Safranin O 염색을 시행하여 조직학적 변성정도를 분류하였고, Ⅱ형 collagen 항체를 이용하여 면역 조직 화학염색을 시행하였다. 결과: Outerbridge 분류에 의한 육안적 소견은 grade Ⅰ 이하가 82.5%였고, Mankin 등급에 의한 조직학적 소견과는 유의한 상관 관계를 보였다. Mankin 등급에 의한 조직학적 소견은 24예(80%)에서 경도의 변성을, 나머지 6예에서 중등도의 변성을 보였으며, 각 구역별 변성 정도는 모두 평균 5점 이하로 경도의 변성을 보였다. 체중 부하부위와 비체중 부하부위 간의 변성 정도에는 유의한 차이가 없었다. Hollander 등의 분류에 의한 면역 조직 화학염색상 결괴는 grade Ⅰ 이하가 28예(93.3%)로 대부분 정상 또는 경미한 변성을 보였다. 결론: 고관절 주위 골절이 있었던 노인 환자에서 방사선적으로 고관절부의 퇴행성 변화 소견이 없는 경우 대퇴 골두 연골의 변성 정도는 대부분 경도의 변성을 보였으며, 부위와 상관없이 전반적인 변화를 보였다. Purpose: To evaluate the incidence, grade and extent of the degenerative changes in the femoral head articular cartilage in the elderly with hip fracture through gross, histological and immuno-histochemical studies. Materials and Methods: The study examined 30 femoral heads obtained from patients over 65 years with no arthrosis by radiograph, who had undertaken bipolar hemiarthroplasty due to hip fracture. The mean age of patients was 79.7 years and the study examined three weight bearing zones (anterior, middle and posterior) and one non-weight bearing zone (inferior) of each femoral head. Results: The gross findings showed significant correlation with the Mankin grade for each zone (p<0.05). Twenty four cases (80%) showed mild degeneration according to the Mankin grade and the others moderate. The mean Mankin score at each zone of all femoral heads was 5 points, which indicated mild degeneration. No significant difference was found between the weight bearing zone and the non-weight bearing zone (p=0.75). The distribution of type Ⅱ collagen antibody stainabilities mainly showed normal or mild degeneration (93.3%). Conclusion: Degeneration of the articular cartilage of the femoral heads in the elderly with hip fracture and no arthrosis by radiograph was mostly mild, and showed generalized changes regardless of the zone.

외이도진주종을 동반한 측두골골종

박일석(Il Seok Park),전승식(Seung Sik Jeon),심정원(Jung Weon Shim),홍석민(Seok Min Hong) 대한두경부종양학회 2015 대한두경부 종양학회지 Vol.31 No.1

An osteoma of the external auditory canal(EAC) is an uncommon benign tumor. If a canal obstruction occurs, ear fullness or conductive hearing loss can arise. But, the association of an osteoma with a cholesteatoma is ex-tremely rare. Therefore, we report a case of a 35-year-old female patient with osteoma of temporal bone that was complicated with EAC cholesteatoma.

오래된 문제, 또 한번의 시도 : 사회복지실천론과 기술론 교육에 관한 교수 및 현장전문가의 인식

김미옥 ( Mi Ok Kim ),장수미 ( Soo Mi Jang ),정익중 ( Ick Joong Chung ),전종설 ( Jong Serl Chun ),심정원 ( Jung Weon Shim ) 한국사회복지연구회 2014 사회복지연구 Vol.45 No.4

이 연구의 목적은 한국사회복지실천교육의 핵심교과목인 사회복지실천론과 기술론이 당면하고 있는 주요 문제들을 진단하고, 향후 개선방향을 논의하고자 한 것이다. 이를 위해 의도적 표집방법을 활용하여 현재 실천론과 기술론을 강의하고 있는 교수 및 현장경력 5년 이상인 전문가를 대상으로 초점집단인터뷰 및 온라인조사를 실시하였다. 연구결과, 현재 실천교육이 당면하고 있는 문제는 실천교육 교수 및 현장전문가 모두 두 과목의 경계가 명확하지 않은 점, 많은 학습내용에 비해 짧은 교수시간 등으로 현장에 적용 가능한 충분한 학습이 되지 않는 점이 제시되었다. 문제의 원인으로는 교수와 현장전문가 모두 실천과목임에도 불구하고, 이론중심의 강의가 이루어지는 현실을 지적하였다. 이에 대해 교수들은 일부 현장경험 없는 실천교육 교수의 역량문제, 현장전문가들은 강의전달식, 외국사례중심의 이론 강의, 자격증 중심의 얕은 교육을 문제의 원인으로 제기하였다. 이에 대한 개선방향으로는 두 집단 모두 공통적으로 현장성 강화를 강조하였다. 다만, 교수들은 이를 위해 교수방법, 교재, 교과목 지침서 등이 중요함을 제시하였고, 현장전문가들은 가치와 윤리에 대한 기본교육 강화를 통해 현장과 클라이언트에 대한 진정성을 가진 인재가 배출되어야 함을 강조하였다. 이 연구는 실천교육의 수요자 및 공급자 측면에서 사회복지실천교육의 현실을 심층적이고 다각도로 탐색한 점에서 향후 실천교육의 방향 설정에 중요한 기초자료를 제공하였으며, 이를 토대로 실천교육의 실질적인 과제들을 논의하고 있다. This study aims to assess issues in pedagogy of the two core courses in Korea`s social work practice education: Theories of Social Work Practice and the Skills and Techniques of Social Work Practice, and to explore ways to improve them going forward. Using purposive sampling method, focus group interviews and one-line survey were conducted with a group of professors currently teaching the aforementioned courses, and social workers with 5 or more years of field work experience. Both the professors and the social workers agreed that the core problem with current pedagogy of the two courses in question come from unclear boundaries between the two courses, as well as the tendency that too much content being crammed into limited course hours. They also displayed mutual concerns with these practice courses are taught with too much focus on theories rather than focusing on more practical knowledge that are more useful in field practice. In addition, some of the professors believed that many instructors lack field experience, making them inherently unqualified to teach these courses adequately. On the other hand, the social workers pointed out lecture based narrative teaching style and excessive use of foreign case study as major problem, in addition to the shallow depth of knowledge transferred, focused only on getting students pass the certification tests. Both the professor and the social worker groups agreed that improving practicality of the course content is the right direction in enhancing the effectiveness of these courses. To this end, the professor group pointed out the importance of teaching style, quality of content, and course guidelines, while the social worker group insisted that basic values and ethics must be stressed in order to nurture practitioners with sympathy and sincerity when dealing with real-world clients. The significance of this study comes from the fact that the issues and possible solutions were explored in depth from both demand and supply sides of the educational content, and it is expected to serve as an important exploratory study that would accelerate enhancement of social work practice education in Korea`s unique social context.

담낭용종으로 진단되었던 황색육아종성 담낭염

홍은경(Eun Kyoung Hong),장명준(Myeong Jun Chang),강경우(Kyeong Woo Kang),전용철(Yong Cheol Jeon),이명석(Myung Seok Lee),김우중(Woo Joong Kim),심정원(Jung Weon Shim),이영철(Young Chul Rhee),정수영(Soo Yeong Jeong) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.4

Xanthogranulomatous cholecystitis is an uncommon focal or diffuse destructive inflammatory lesion of the gallbladder. It is characterized macroscopically by yellowish tumor-like mass in the wall of the gallbladder, and microscopically characterized in the early stages by a large number of foamy histiocytes and acute inflammatory cells, and in the )ater stages by increasing fibrosis. It has been usually mistaken for gallbladder cancer and often seen with stones. A case is presented in which a 59-year-old woman with clinical gallbladder cholesterol polyp was found at surgery to have a edematous and thickened wall of gallbladder, multiple black pigmented stones and 3 x 0.5cm sized yellowish mass on gallbladder bed which was confirmed later as xanthogranulomatous cholecystitis, pathologically. (Korean J Gastroenterol 1996;28:582 - 586)

자궁의 악성 혼합 뮬러리안 종양 1례보고 : a case report

심정원,조혜제,고일향 인제대학교 1990 仁濟醫學 Vol.11 No.4

A case of malignant mixed Mu¨llerian tumor (M.M.M.T.) of the uterus is presented. Malignant mixed Mu¨llerian tumor (M.M.M.T.) containing both epithelial and stromal component is subdivided into two groups, homologous or carcinosarcoma and heterologous or malignant mixed mesodermal tumor, by the histologic finding of its stromal component. Relation with previous pelvic irradiation in M.M.M.T. is well known. A 62-year-old female patient visited Sangye Paik Hospital for her routine check-up, and pelvic mass of double man's fist size was found on rectal examination. She had been given pelvic radiation therapy three times about two years ago, for invasive sguamous cell carcinoma of the uterine cervix (stage IIIb). The Specimen by subtotal hysterectomy, showed a polypoid mass, filling the emdom etrial cavity and the cut surface of this mass disclosed smooth myxoid fish-flesh appearance with multifocal hemorrhage and necrosis. Microscopically, the tumor was mainly composed of sarcomatous component with minute adenocarcinomatous component. Cross-striation, which was demonstrated in the PTAH stain, was rarely present in the malignant, pleomorphic stromal cells.